Introduction to EGFR inhibitors

[@tusharkush7]

The mutant receptor does not act like becaons for TKIs. TKIs bind with high affinity only to mutant receptors while they also bind wild type receptor with less affinity causing side effects.

[@poonamnaphade1605]

How to manage adverse effects of EGFR inhibitors like paronychia or skin lesions?Thank you .

[@thebiglagovski139]

Thank you ! How long does it takes for tumor to develop residence to EGFR inhibitors ? Months?

[@florianthomas7852]

Tarceva shows a median of response until resistence of 8 months in lung cancer with active egfr mutation.

[@maisoonazzam8830]

Thank you

[@prithvirajsinhgohil9584]

Is TKI also affact other organ when tumor spreads from lung to spine?PLZ ANSWER I NEED TO KNOW BADLLY.

[@logitechmk350]

Same question

[@ayudiahmayasari1182]

Yes,as long mutation is positive

[@PaperakuZ]

gave me cancer