Is This Allergy Medicine Unhealthy?

[@DoctorMike]

Go to ground.news/doctormike to verify the source of your information and see through biased reporting on health, medicine and more. Subscribe through my link to save 40% off unlimited access.

[@meryembenkhayi]

❤ okay😊

[@BrandelSaundh-e6f]

@@meryembenkhayiyup doctor mike is the best doctor ever better then other doctor in the whole world 🌍

[@bluetinsel7099]

You also have to look at interactions with other meds that are being taken, combining certain meds could also be an issue. If it’s taken alone it could have a different effect.

[@BrandelSaundh-e6f]

@@bluetinsel7099 do you think he is a really doctor 👩‍⚕️

[@Alaskaspetkangaroo]

could you react to kpop idol diets? Some are really extreme

[@theraven3554]

Benedryl, because you can't sneeze if you are unconcious.

[@vladimirmihnev9702]

Yes but you also can't run from the hat Man! And he usually goes after people on benadryl, at least that is what I have heard. I was totally clean when he showed up 😅 not fun not even a little bit!

[@undercoverjihadi9252]

It's hard to sniffle when ants are crawling up to your brain through your nasal passages.

[@effmltalks]

AAHAHAHA

[@LittleMew133]

LUL

[@Arcturus218]

To be fair that is true lol

[@oscarwildin8143]

As someone with anaphylaxis allergies, Benadryl has literally saved my life on multiple occasions, by buying me a little time to get an epi pen. Seeing this video title had me like :0 . I’ve had many allergists, including ones that were literally top of their field, and all of them Swore by Benadryl. I feel like we’re not talking about the fact that Benadryl is super important for people with severe allergies.

[@AD_AP_T]

This is so surprising to me: diphenhydramine is rarely used for that in Aus, and is specifically recommended against because the sedative effect can make it unclear what's the drug and what's the allergy in an emergency. Cetirizine is used instead, or sometimes fexofenadine.

[@EPfruitbooter]

Same - but what actually is it about Benadryl that makes it better for severe allergic reactions compared to other allergy medicine?

[@okcoolbro3]

​@@EPfruitbooterBenadryl works faster within minutes where other allergy meds can take up to 1-3 hours to work. So if in an emergency aka your throat closing benadryl will work faster but obviously you will have to be monitored during it because of drowsiness. Also an epi is still recommended and usually a trip to the hospital or doctor right after. As someone with a several allergy same benadryl has saved me a couple times. That's why I always carry my inhalers, benadryl, and epi with me because my lungs and body don't like air sometimes. 😂

[@okcoolbro3]

​​@@AD_AP_T Many recommend it here because it works faster than other forms of it. So while ya you'll be drowsy af, at least you can breathe enough to get an epi or call for help.

[@ghillies4life]

Then your risk-benefit ratio has changed. It doesn't make Dr Mike's video wrong.

[@adritisengupta]

This series of TRUTH OR SCARE should be an international show on TVs and Radios for people to know more and be aware. Congrats Mike, you have one more hit series with excellent work. We want doctors like Mike.

[@xm8553]

It is lol. Anyone can watch it anywhere in the world, and it’s on a free “network” (KZbin). The problem is that there’s so many other videos out there and the people who need this info the most probably aren’t looking for this info

[@birbanimationsfan9502]

these videos feel slightly scripted (it's a bit obvious he's reading from a teleprompter). They aren't as fun or interesting as freestyle ones he usually does.

[@AdultingsHard]

Always listen to your DO and PCP, but if your immunologist tells you to eat benadryl due to an illness that necessitates administration. Listen to them, over the PCP... (I have a mast cell disease and Benadryl works best on my "flare ups".) Luckily I do not need to take it often and hopefully one day, I find a better option.

[@jeanaprewitt9658]

What the world needs is for children, instead of being given busy work, to have required classes on critical thinking. It's too late for most adults. Kids need to learn to see things from different angles and learn to require legitimate verification before accepting "facts" or dismissing "fake news."

[@yanelisalmira4680]

​@@birbanimationsfan9502that has no impact on the original comment

[@yippykiay13]

As someone who has talked to many doctors over the course of my nearly lifelong struggle with chronic insomnia, I can tell you: doctors need to do better. The only doctors that ever took me seriously just put me on drugs MUCH worse than Benadryl, even after I told them I’m not looking for a quick fix, I’m looking for a treatment. Why is it so hard for doctors to take insomnia seriously when it is detrimental to the lives of the people who suffer from it????

[@tanyakilbane7636]

Some people are sociopath. That is why. Just in it for the money

[@shelbylabass285]

I’m in the same boat as you with chronic insomnia for a good portion of my life as well and I unfortunately I take multiple pills including diphenhydramine to try to get some sleep. Without it, I doubt I would sleep much, if at all. I agree with you, doctors are not much help with this and some of the other meds mess me up pretty badly with some awful side effects. It’s hard to not be sad hearing this because I don’t have a choice.

[@amykathleen2]

Have you ever tried CBTi (cognitive behavioral therapy for insomnia)? According to my doctors, it’s considered the first line and best treatment option for people who have insomnia, as long as their insomnia is not a symptom of another underlying medical condition.

[@lynbaker]

Benadryl is the only medication that works for my issues. The new antihistamines don’t touch my symptoms. Having said that, I have taken Benadryl everyday for over 30 years at bedtime. Plus, I take other medications like this for gastric issues. In a word, I am screwed.

[@supercalafra]

Even people who smoke daily aren't guaranteed to get cancer. In fact, the risk is lower than you might think considering the scary ad campaigns. You're not screwed, but you are probably at an increased risk if there is a causal link.

[@AdultingsHard]

I am told by my doctors to eat Benadryl when im having a Mast cell disease flare up.. If it wasnt for Benadryl i wouldnt be alive. I hope he puts in a note early on, before someone that isnt well versed, ups and stops taking this medication and gets sick or worse because they stopped taking Benadryl because someone on youtube suggested they dont.

[@evad687]

I’d reach out to companies researching this sorta thing and offer yourself up as a case study or as a data entry

[@vibrantgleam]

@@supercalafra Smoking is still bad though. Many other risk factors.

[@felixrowan646]

You aren't alone in that sinking boat. Honestly, if this is the cost of getting a good nights sleep I'll take it.

[@Moon_x_sun]

FYI for people living in denmark (maybe other European countries) Benadryl here contains a different active Ingredient named acrivastin. Diphenhydramine is in benylan tho wich can be bought in pharmacies but it has a no driving warning attached to it. So for anyone who have taken benadryl it’s not the same as the American

[@vickithomson4470]

Other variants use cetirizine hydrochloride as well. I find it does not work well and tend to take chlorphenamine maleate (piriton)

[@brendatomlinson]

I googled and acrivastin is not available in the USA. It was discontinued in 2020.

[@juliav.mcclelland2415]

I abused benadryl as a sleep aid back in college. I'm doomed. Hopefully never smoking and having a 101 yr old grandfather with no mental decline will balance it out.

[@supercalafra]

You're not doomed. Even if there is a causal link the odds are still likely to be in your favor that it didn't cause much harm.

[@melanieluver4eva]

did you ever see the hatman

[@john-wx7gr]

what if you, hypothetically, were also an alcoholic with a family history of heart disease and dementia. asking for a friend

[@justinjalenleetiller]

the best you can do now is to get into alcohol

[@juliav.mcclelland2415]

@@supercalafra Thank you!

[@sommer447]

This series is so so important I hope Dr. Mike is putting them all in their own playlist for everyone in years to come.

[@multieyedmyr]

My mom abused it to sleep for years. She would take half a dose but has been doing so for decades. Is now showing signs of dementia, paranoid audio and visual hallucinations. Everyone is talking about her, stalking her, zapping her with lasers from their phones that cause her pain. She’s always been a rock in my life. It’s hard to see.

[@MBT372]

How old is she now?

[@evad687]

Delirium is an effect of high doses of DPH, and can basically cause long term symptoms if misused. People that overdose on benadryl often report seeing hallucinations for weeks or months after, even if they haven’t taken it again.

[@Imzadi]

This is so scary. I had no idea. I’ve been taking it as a sleep aid for over a year! 😮 How long did your mother take it?

[@kari34b54]

@@multieyedmyr Are you sure it was only the Benadryl? I hope you brought her to a psychiatrist or therapist.

[@Jackson-qi4rw]

I'm going to be honest it's not the benadryl that's doing that

[@Familylawgroup]

Considering I was just in the ER in for issues with Benadryl and my other medicines that combined to reduce my breathing, I find it fascinating that you are addressing this topic. I was taking it to try to control unrelenting itching from eczema flare up.

[@thesunlightguardian]

I'm only a minute in and THANK YOU. I have some people say stuff like that they take a sleep aid, allergy med, and tylenol pm because "it's evening." They don't realize they are triple dosing on a med and they SHOULDN'T double up on allergy meds because they only took one

[@justahugenerd1278]

That and also it's not normal to need a sleeping aid to begin with. You should be talking w your doctor about this, especially because so many sleep issues can be fixed with lifestyle changes

[@PinkRose0910]

People should learn to read the package directions with the Warning labels. It’s not that hard to read first before taking.

[@thesunlightguardian]

@PinkRose0910 I actually understand not reading all interactions and such, but to not even know what the ingredient is...insane

[@Unknown_Genius]

@@justahugenerd1278 Exactly. Medication as a sleeping aid (especially on a constant basis) is a last resort when everything else fails. I e.g. have to take an aid for it, as I can't fall asleep, sleep through or even feel tired on occasion without it (sometimes I can't even sleep when taking the aid, yay - helped me a ton to actually get sleep tho so I'm not complaining), obviously we tried a lot of things previously (including but not limited to changing lifestyle aspects, reducing screen time especially in the evening and so on). I also don't know why people are so persistent on medication as sleeping aid out of choice without even talking to doctors (if freely available in the region they live in), all of them have the potential of addiction, overall making it a vicious cycle to get rid of - not to mention the side effects some of them may have (the one I take e.g. is usually being used in a quite a bit higher dosis for schizophrenia, so something you'd normally not want to even play with if you don't absolutely have to as it still maintains a small potion of its normal case use effect).

[@snaifhassnan6348]

186

[@rain73ful]

As a person with many food and environmental allergies, Benadryl has been a life saver for me. Using it has helped me to avoid using my Epi-pen many, many times. When you use the Epi-pen, you usually have to stay in the E.R. for a few hours to be monitored for a "rebound effect", which can happen in anaphylaxic reactions.

[@carolcline2830]

Mast cell activation syndrome?

[@OlrunEclipes]

Fun fact: benadryl is the main drug we use for chemotherapy reactions. We use a IV form and tablets. It is fast acting and(keep in mind given with many other drugs) works best for a allergic reaction. We do require a driver because iv has even more drowsiness side effects. But the fear about benadryl doesn't help. Chemotherapy works against cancer. But it is tough if the body, and certain drugs, while they work against the cancer, are highly reactive. People are already scared of chemotherapy, we can't have them being afraid of the pre-meds as well. I work in a hem/onc infusion room

[@MrMikk532]

Just about to say something similar to this! I have MS and get Benadryl plus a steroid for my infusion premedication. I'm already worried about cognitive function and don't enjoy the drowsiness side effect as someone who struggles with fatigue, but I understand that I don't abuse benadryl or use it as a sleep aid. All medication should be used as indicated, at the lowest effective dose, and when no lifestyle changes can fix the issue. I was shocked when I heard my own roommate used it as a sleep aid NIGHTLY! I hope the sudden media attention doesn't scare away legitimate use, and hopefully brings more attention to further studies to understand long term impact on its use

[@yettykitty4893]

Speaking of IV Benadryl, one time I received this before an endoscopy in addition to Versed and one other medication that I can’t recall. The fast IV push of the Benadryl sent me into an indescribably horrific full blown panic attack!!! It was easily the top most distressing moment/feeling of my 52 years on this planet ! We had to re-schedule the endoscopy in the OR with an Anesthesiologist and they used propofol. I don’t recall any of it. The second and last time I got IV Benadryl was when I was having an allergic reaction to Clindamycin. IV Benadryl was one of a few medications I received. Once again I absolutely spiraled into a panic that there are no earthly words for! I will never allow IV Benadryl into my veins for the rest of my life! I certainly don’t take the OTC pills either. I get severe insomnia, restless legs and magnified anxiety. Does anyone know why I react to Benadryl this way, especially if it’s a fast IV push?

[@PinkRose0910]

@@yettykitty4893No dear. Did you ask your doctor? Everyone’s body chemistry is a little different. Maybe it interacted with another medication in a way that messed with your brain’s chemistry? I’m not well versed on panic attacks though.

[@professional.commentator]

My mother used to be on chemo and the worst drug for her was Benadryl. It got so bad that she thought she was going to pass out and the nurses had to switch it out for an alternative.

[@pseudoruu]

​​@@yettykitty4893this actually ended up happening to me, unrelated to chemo. i'll never forget the IMMEDIATE disorientation, and to date it's some of the worst anxiety i've ever had. i felt like i was gonna ɗ¡é. i remember being given anti-nausea meds beforehand but i really doubt it was interacting with the benadryl. i asked the doctor about it, "oh, well sometimes you can get dizzy if the meds get pushed too fast." absolutely not, dude... if that was true i would have experienced it at some other point in my life. i tried looking it up myself when i got out of the hospital, and i did see a few other people mention it happening to them as well. this is basically just a long way of saying "same, idk" so take from it what you will 🤷🏽‍♀️ i just know that me and benadryl will never stop being enemies lol edit: i remember my mom also got anxious when she was given benadryl, so maybe we're all just built different lmao

[@creeperyellow]

As someone who takes benadryl for allergic reactions, the sedation is a lifesaver to recover from serious incidents

[@gradyrector6752]

I am a Pharmacy Student and in one of the first otc drug class we learned is to not recommend Benadryl (Diphenhydramine) to patients over the age of 65 and under the age of 12, also to not take it more than a week.

[@T_T-T_T]

Do you mean more than once a week?

[@69n420]

What about 2-3 year binge

[@gradyrector6752]

@@69n420 I would not recommend doing that.

[@Anthony-hu3rj]

@@T_T-T_T It's implied, obviously. Errata Happens.

[@snaifhassnan6348]

79

[@kitkatwaffledeath]

Hi! I am allergic to mosquitoes and their bites. Not deathly allergic, but I puff up about 2x more than a regular irritated bite (Pediatrician). So, this video was really helpful to get me to school on time without being too tired to function, or too itchy to function. Thanks, Mike!

[@tamicoil7069]

I use Benadryl because it works better than rhe newer ones. I've tried several , and keep coming back to Benadryl because it works best, despite making me drowsy.

[@chronophobiasdelirium]

Nice to see someone else like me!! Don't feel bad about it, stay informed always! :) ❤ Have a good day

[@legzfalloffgirl5148]

I used to use it because it's inexpensive compared to other brands

[@whitneysanders6996]

It works best for me too

[@jj96432]

if u have recurrent allergic rhinitis, nasal steroids are probably a better choice

[@parley1994]

Rather be sleepy than miserable.

[@jerrywood4508]

I stopped using diphenhydramine both for sleep and as an antihistamine when I read it was sometimes associated with restless leg syndrome. I had been experiencing increased restless leg, which was driving me to desperation. I stopped the diphenhydramine and I reduced my experience of restless leg by at least 90%. Let me say that I'm a great believer in the power of placebos, and that might be what's at work here, but I don't care.

[@aliciat2532]

It gives me restless legs too! Drives me nuts

[@lorisewsstuff1607]

My son and I are allergic to pork, specifically an enzyme pigs make but humans don't. I can tell you, Benedryl works better and faster than other antihistamines when I'm having a reaction. My son's reactions are more dramatic than mine. He's been hospitalized several times. Every time, the ER gave him intravenous Benedryl in conjunction with epinephrine to stabilize his condition. Having a major reaction is stressful and the sleepiness is helpful in relieving that stress. The last benefit I can thing of is there is a topical version of Benedryl that's readily available. It's great for mild reactions that just cause a rash. I can smear some on the rash and go on with my day. What does concern me about the anticholinergics is that I take Ropinerole for restless leg syndrome. I think it falls into that catagory. I will have to look into this. Thanks for the info.

[@japanpanda2179]

Yeah, anticholinergics can definitely make restless leg syndrome worse.

[@AdultingsHard]

I have to eat Benadryl every once in a while for my Mast cell disease "flare ups" My doctors tell me its perfectly fine for me to do. Luckily i dont have to eat it very often. I wish Mike put in a note for specific circumstances where people need to eat it......

[@ammlseri5769]

Ropinirol is a dopamine-agonist, anticholinergics (specific antimuscarinergics) are used to treat specific movement disorders, usually those caused by decreased levels of dopamine (such as in Parkinson’s disease or people using antidopaminergic drugs for psychiatric disorders). Unfortunately can’t give information on why RLS responds to dopamine agonists but is worsened by anticholinergics

[@ksc743]

@lorisewsstuff no offense but why don't you and your son just stop eating pork, like people who can't eat peanuts?

[@justinjohnson4278]

I think if you are using it as an occasional thing to combat large reactions as opposed to daily use, I bet you’ll likely be fine

[@sarahmascara]

As an educator, I love the way you're addressing critical. thinking skills! Especially in this world of conspiracy and disinformation campaigns, it's so important people learn. how to distinguish fact from fiction.

[@Lalaland_lady]

I heard about the study. And was concerned because I took Zyrtec daily for allergies. My allergies are chronic. I also have a lot of fatigue and mental fogginess. So I decided to stop taking Zyrtec, even though it wasn’t in the study. I Think it was a good decision. I have a lot more energy during the day. My mental faculties seem clearer. I do use a lot of Kleenex now, but that is a small price to play for possibly delaying or avoiding dementia. I am a 62 year-old retired nurse. Thank you for your show Dr. Mike.

[@milanprolix2511]

The active ingredient in Zyrtech is Cetirizine which is a second generation antihistamines. I think it does pass the blood brain barrier (not sure) but it is so much more specific to H1 receptors (the true target of antihistamines) than first generation antihistamines that is almost does not interact with neurotransmitter receptors (dopamine, acetylcholine, serotonin,...). It is specific enough to not exhibit anticholinergic effects. Although it might make you slightly more drowsy, it is (at least in Europe) much more affordable than third generation options and widely available.

[@RyanMorash]

@@milanprolix2511 Cetirizine does pass the blood-brain barrier, but only slightly

[@donnadrane4977]

Maybe allergy shots could help you.

[@vickiethompson9245]

For sinus allergies, try local honey. It can help decrease your symptoms.

[@bobbi-jochoudhury2467]

Search the connection between gut health and allergies and fix the issue from the root then you can take less Zyrtec

[@patrickobrien5311]

Dr. Mike, my wife has Ehlers Danlos Syndrome (EDS). It is difficult to find good info on the condition and it seems to affect everything in the body. It is also a fairly interesting topic. Could you do an episode on EDS? (I'm sure my wife would be open to speaking on her experience with you if that helps too).

[@stephaniem8278]

My best friend has EDS too. I would really appreciate a video on this topic as well.

[@GraemeMarkNI]

My lung doctor tells me that asthma increases dementia risk. You’re always balancing the risks of the medication with those of the disease itself.

[@supercalafra]

Good point. Autoimmune conditions may be the link to dementia, rather than the medication people take for it.

[@AdultingsHard]

This is a great comment. I have to take Benadryl every once in awhile for my Mast cell disease flare ups. No other antihistamines work for my flare ups Like Benadryl does other than a handful of pills.. Like you said. Its a balance, and luckily i dont have to eat Benadryl often.. nor do i have to eat a hand full of pills often.

[@cheyennepulsipher5448]

I'm doomed😂 I'm asthmatic and use Benadryl for severe allergic reactions (non-food related)

[@kari34b54]

Well, I am screwed if my allergies don’t kill me first.😂 But take Benadryl or die of allergic reaction? I’m still taking the Benadryl.

[@lanabahn9735]

I just watched trust me bros craziest drugs videos and I feel so knowledgeable knowing exactly what Dr. Mike is talking about

[@63Reed]

I always forget Benadryl can make some feel drowsy. There is one instance where Benadryl helped me fall asleep. It was when I experienced “Hell’s Itch,” a form of sun poisoning. It wasn’t until got relief from the Hell’s Itch, that my mind was able to calm down, that I was able to fall asleep. For context, I was experiencing it for hours that day. The possible side effects I have noticed are nothing, hunger, or irritation, but never drowsiness. In fact the times I have taken it, the irritation results in difficulty falling asleep.

[@JaneMiller0101]

Does not make me sleepy. Helps a lot when my nose won’t stop running.

[@aliciat2532]

It used to make me sleepy. Now it makes me fidget like a meth head

[@doxfie.]

1:10 because if you have a strong allergy the newer antihistamines don't do sh*t. you can be so legarthic/sleepy from the allergy that diphendrymine is your only option to function normally, it does make you awake (paradoxically) with all the cognitive side effects obviously (for which choline somewhat helps)

[@chase5436]

When I was being treated for severe depression, the nurses would give me liquid benadryl to calm me down. Getting the IV put in would give me crazy panic attacks and the benadryl was the only thing that would calm me down.

[@MM-pv5tp]

Why tf would you need an iv for depression?

[@Seth9809]

Understandable.

[@DobbysStinkySock]

Was given an antihistamine for depression, hydroxyzine, and it made my anxiety and depression worse, caused suicidal thoughts and panic attacks. Was crazy. It's actually insane how bad the side effects can be for some people when the brain is affected

[@NK-pr9xy]

​@@MM-pv5tpSevere depression can present with psychosis for some. Depression as a disease is more than feeling "sad".

[@jenanne31]

Thanks, Doctor Mike! I regularly take Benadryl as a sleep aid. Perhaps it's time to rethink that! Love your content.

[@alexiagonzalez279]

I love this content. As a medical student it is very useful and interesting. In fact, the video on BMI was my starting point to begin my research to present it at my university symposium this year. Thank you very much, doctor.

[@EasterEdwards]

I've been waiting, another upload from you!

[@lauratopliffe8179]

Every Sunday at 10 am ET.

[@leruetheday377]

My doctor told me to take diphenhydramine for my vertigo and severe allergies. It works!

[@nataliesue2485]

Benadryl drowsiness only effects me for the 4-6 hrs that it works. However, any 24 hr allergy med will make me drowsy for the whole 24 hrs. So I use Benadryl and/or Sudafed (the one you get from the pharmacy). I only take them at night. Because even the Sudafed makes me drowsy. I have to rely on EmergenC, hot teas, cough drops and essential oils for the daytime.

[@ML-dk7bf]

You know what's worse than Benadryl drowsiness? Dealing with the after effects of hornet venom for days when I didn't have it on me.

[@WhatsBliss]

I’ve had trouble falling asleep my entire life. For a period in my teen years I was using Benadryl fairly regularly to fall asleep. Fortunately my doctor turned me on to melatonin when I was 16 (and luckily my psychiatrist gave me more info on how melatonin works). Between a super low dosage of melatonin and better sleep hygiene I now don’t use any other sleep aids.

[@professional.commentator]

When my mother was going for chemo, the nurses gave her Benadryl through the tubes and she felt a lot of heart pain from it. She said Benadryl was worse than the chemo drugs themselves. The nurses eventually had to switch it out for an alternative.

[@evad687]

yeah, it can definitely stress out your heart. people that OD on it can get torsades de pointes

[@marinesniper1012]

Benadryl in IV form is extremely potent and is really best administered diluted. I usually dilute in 20 ml of normal saline and push very slowly. Sounds like it was given through a port which leads right to the heart. When given peripherally and un-diluted, it burns like you couldn't imagine.

[@professional.commentator]

@@marinesniper1012 Oh wow. Well that just shows those nurses were lacking some training or awareness. 🙃

[@Giavekz]

Im so sorry your mother went through that... hate to say it, but that sounds like malpractice

[@hopeparker5288]

I had a heart attack after just taking Benadryl and I didn't take it often or for many seasons. Only when my symptoms were really bad.

[@rileyluver16]

I would be curious to see the correlation between anticholinergics and pre-existing conditions such as EDS. Because they know that things affect us different when there is a pre-existing condition

[@nicole07700]

This video isn't to scare people, but rather help people understand Benadryl. had a severe migraine and was given benedryl, toradol and magnesium at the ER. They said the benedryl enhances the cocktail of meds. I was exhausted when I was leaving to go home. It was horrible.

[@PunmasterSTP]

I like how when antihistamine action occurs in other medications (like psych meds still on patent), it can be talked up as helping with sleep and staying calm, but if it's just generic diphenhydramine then it "disrupts sleep architecture"...

[@aethylwulfeiii6502]

Psychiatry is literally the lack of knowledge of the neurological system. We don’t know what’s wrong so here is a bunch of toxic pills. The lack of diagnostic testing for medical diseases in psychiatric hospitals is disturbing.

[@PunmasterSTP]

@@aethylwulfeiii6502 I agree it's disturbing. To be fair, it makes sense to me that there would be a lack of diagnostic testing because the mind is just such a complex machine and we don't really understand it. If trying to treat an issue comes down to trial and error and a doctor isn't sure something is going to work, as long as they are upfront about the potential risks and benefits, I think trying different meds could be worthwhile. But there's just such a potential for people to make outrageous and unsubstantiated health claims and put people in danger for profit.

[@forthewinberly]

I had dystonia/tardive dyskinesia for almost 15 years and have MCAS. Soooo many anti-parkinsonian medications and antihistamines, including Benadryl. My doctors all have me refusing any medication that can potentially cause a movement disorder on file, and I do my best to reduce stress and avoid anything that I know trigger my MCAS.

[@luanawilchek644]

I've been talking Benadryl for over 50 years. Doesn't make me drowsy.

[@drdabb]

Because of the sedative and mind-altering effects of diphenhydramine, it is not recommended to give to children because there is increased risk of mortality. It’s recommended that you give them Claritin, Allegra, or Zyrtec and can give double the recommended daily dose for acute allergic reactions. On the flip side, kids can also get super hyper while taking diphenhydramine, which may be due to the brain-involving aspects of the medication.

[@Idk_Shinobu]

Watching Dr.Mike while currently at a hospital is oddly satisfying to me 😅

[@justahugenerd1278]

You doing okay?

[@Idk_Shinobu]

@@justahugenerd1278 yeah i had a blood clot a few days ago and it started swelling but I’m fine (I shouldn’t be getting them at my age tho so I’m still concerned)

[@SilverScale.]

​@@Idk_Shinobu Hope you're all the way better now and nothing scary potentially in the future!

[@Idk_Shinobu]

@ thank you! 🙏🏾

[@Here2Enjoy-b8z]

1:25 we use the benadryl liquigels. We cut open and apply the medicine directly on the sunburn area or allergy area (ran out of cartizone or something and tried it this way and it worked fine in our case).

[@elgibby5]

My name is actually Charlie G so I was a bit spooked at 3:05 when I saw my bias report that I never knew I made. But in seriousness, great video, well-researched and easy to understand.

[@nanispisspot]

damnn😂

[@sparklefairykitten]

Hmmm. I've been using Benadryl to help me sleep every night for the past year. I was already having doubts about continuing, but this video really makes me think I should stop. The problem is I don't know what else to try. I take melatonin but it doesn't help as much as it used to. Thats why I initially added the Benadryl.

[@LuckyPigeon1111]

There are people who purposely OD on Benadryl. Yikes!

[@beepboop9848]

so they can see the hat man

[@melavery9210]

Man, I used to do that in my younger years. What a messed up way to live.

[@RubyMc-v4i]

⁠@@melavery9210yes me with night nurse in my youth…

[@Ahov]

I overdose on LSD, DMT, weed, shrooms etc

[@keeferChiefer]

@@AhovMaybe DMT but everything else no you don’t, not even close.

[@theunwantedworld1]

It’s saved my life more than once especially going into anaphylactic shock from food allergies.

[@chickenskink1]

So grateful for these debunking videos!

[@courtneyisaseagull]

I really appreciate your breakdown on this topic, Dr. Mike. Thank you for the informative video!

[@coyoteinthepool]

Sleep is a freaking puzzle, man. Utterly brutal problem.

[@londynleslie9944]

I’m 15 years old and usually take Benadryl for sleep, but after watching your video, I plan to stop once I recover from this cold. I really hate colds; I feel like I can't breathe. Could you please make a video about colds? Like how to get over it quickly and what you can NEBULIZE. Thank You!!!

[@carriehollyland3596]

I take Benadryl as just one part of my allergy treatment course. I take it to specifically not only help me with an allergy flare but to also help me sleep during that allergy flare. Meaning I only take it when my allergies r flared and I only take it at night because I know it will knock me out and I am relying on that to help both treat my allergies as well as help me get some sleep at night during that flare at the same time (due to my allergies preventing me from being able to get a restful night's sleep). During the day however I use a different one, I use the non drowsy allergy meds (prescribed by my doctor) instead. I also use creams for skin allergic reactions (I suffer from more than one type of allergy). And I also am currently getting allergy shots to try and help actually cure me of the allergy (and so far it seems to be working).

[@AdultingsHard]

I hear ya. I have a mast cell disease and this is all par for the course for me on some days. Mostly through avoidance i dont need rescues and topicals though. Unfortunately i do have to eat benadryl every once in awhile to fight Mast Cell flare ups. Luckily not often, but its either one benadryl or a literal handful of new age antihistamines to get my flare up under control. I would rather save my liver and kidneys the issue of possible toxification though. One guy above said it best. Its a balance. Asthma can cause dementia and benadryl stops asthma... so if you need it... well drat, but it some cases its a give or take.

[@Kitkatattacksssss]

I feel ya, during pollen season I break out in hives when birch and oak pollen are bad on top of it triggering respiratory issues with my asthma. Benadryl is the only drug able to calm the reaction, I wouldn’t be able to sleep let alone function without it. I used to see an allergist before insurance wouldn’t cover it anymore and my allergy panel is terrifying. Allergy shots were helping but like I said insurance. I’m on a few different types of allergy medicines year round that fluctuate how many I have to take by what’s in season. My doctors are well aware of what I take and understand in my situation I have no other option. Benadryl is not optional in spring and late summer.

[@brendatomlinson]

I will only take Benadryl as a last resort usually when allergies are affecting my eyes when they’re puffy and itchy. The effects of Benadryl lasts me at least 24 hours, usually into a second day. The box warning says not to take if you have depression. I do have depressed symptoms the day after.

[@BertieMiner]

secondopinionfromai AI fixes this (AI Medical Reviews). Indeed.

[@bethg7026]

When i get a migraine, diphenhydramine allows me to sleep for a solid 8-12 hours. I have EDS and unmedicated my sleep is fairly disrupted, and jsnt enough to allow my body to reset itself and break the circulatory issue causing my migraine. So for me, its a lifesaver due to its side effect.

[@shanthoshamadhavan2631]

Doctor Mike Strikes again with a BANGER of a video.

[@olivialoreto]

I love this about Dr. Mike so much that he is so real with us.. like he doesn't act like some god who hasnt made any mistakes and actually accepts to certain things it's so human of him... Thank you Dr. Mike!

[@melavery9210]

I took Benadryl every day for almost 10 years until I read an article and contacted the doctor doing research. She told me to get off it immediately.

[@SomeoneIusedtoknow-s1f]

The person doing a study trying to prove their case, when all evidence is currently anecdotal at best and currently cannot prove a cause ESPECIALLY with how many autoimmune diseases and other chronic health issues exist that could be the actual root causes of dementia.... Is obviously going to tell you to get off it. They're biased, and they're speaking from a place of bias, especially without current evidence and proof, and especially without being ABLE to prove its not underlying conditions causing people's dementia. Youre saying you listened to a biased doctor, who is trying to prove something is causing something else.... When the majority of chronic Benadryl users have underlying conditions beyond normal allergies. Doesn't say much.

[@elizabethb9521]

Another amazing and informative video. I appreciate the clearly non biased evidence of both sides and that he just opens up the conversation for his viewers to learn more about the topic and research more on our own. It’s scary because when I was little, I was recommended Benadryl to help me fall asleep as I had severe ADHD and insomnia/nightmares. It was the only thing that worked at the time, but as the years went on, my nightmares and drowsiness became too severe that we stopped it. I am now weaning off my current sleep aid that I’ve been taking since I was roughly 16 years old (I am 24 now) - Trazadone. And wouldn’t you guess it, trazadone is prescribed as an off label sleep aid (it’s actually an antidepressant). Very interesting stuff. I hope Dr. Mike continues to cover more medications and possibly sleep studies as well! Thanks again for the informative video!

[@jewel65]

Trazedone gave me crazy dreams & massive cotton mouth. Now that I have high blood pressure, heart failure I can't take it.

[@Thommadura]

I am interested in what YOU think of cooking food in an air fryer - which is basically a convection oven with a faster fan. They do crisp veggies pretty well without using oil for cooking. I have been making Potato Fries in mine without any oil added -(although some use a little spritz of oil) .

[@aimeetorres323]

Cooking with plastic….

[@amir.r1639]

​@@aimeetorres323😂its thermodynamics not plastic

[@mainefobfan]

I live on Zyrtec for my allergies and when I skip a day because I might have forgot, I know it. Been taking Zyrtec so long that I needed a prescription for it 😅 Always I love that it’s nondrowsy but affective. Year long allergies club allergic to dust.. dustmites 🙃

[@mainefobfan]

But I’ve only taken Benadryl My allergies have been really bad and I needed to sleep.

[@livinglifeblessed1]

I sneeze so many times in a row when I have an allergy fit 😂

[@Jennifer-nz2ss]

I take it too. I'm allergic to everything 😢

[@readtheroom831]

Year long allergies club unite! 🫡🤧

[@kayleelamonica1600]

I've been watching your videos for years just for fun, probably since middle school. Now I'm more than halfway through nursing school and all the science explanations make more and more sense to me lol. Just wanted to say thanks for making these videos!! They're super interesting and inspire me to provide the best patient care I can :)

[@Aziza-qk5tj5ji6x]

I love all the information about Doctor Mike and I really like his personality❤❤❤❤

[@donnadrane4977]

Long time allergy sufferer here. Benadryl is the best anti histamine out there for an allergic reaction. If I only have mild symptoms, I will take a Claritin or Allegra, but for the more severe reactions Benydryl is best.

[@LisaAlizaZips]

My friend who takes benadryl everyday just asked me if benadryl was healthy to take often now I can send her this video

[@orcapilot-o8n]

Twice a day during hayfever season, once a day otherwise.

[@6000countingdown]

Her best bet is to visit her GP or an allergist so she can ask the question with the specifics of her circumstances. My mother has a genetic anomaly that requires she take several antihistamines of different types (H1 and H2) in addition to monoclonal antibodies on a daily basis simply to function. The specifics of you friend's circumstances matter, and that's something that can't be answered on a KZbin video.

[@LuisaD93]

I’ve taken it when young for allergies and I can say that without a doubt I’ve felt less cognitive the next day and finally realized it was the Benadryl. When I stopped taking it altogether the symptoms cleared up and haven’t had any episodes of feeling lost since. I use loratadine now.

[@Malaikamuskan-v5z]

Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.

[@xx_-love-mags354]

Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!

[@BenjaminCanales-nn9gi]

Yes, steve_porassss. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.

[@xx_-love-mags354]

Is he on instagram?

[@ejmabrothers6743]

Microdosing helped me get out of the pit of my worst depressive episode, a three year long episode, enough to start working on my mental health.

[@BenjaminCanales-nn9gi]

Absolutely, his offerings extend to global delivery, prioritizing complete confidentiality for individuals valuing their privacy.

[@LabCat]

I use Benadryl specifically for its hypnotic / sleep effects when I'm in an insomnia bout. But I don't use it for allergic reactions, as the only thing that affects my allergies is Sudafed. I'm a documented high metabolizer of most drugs including opioids, so I'm definitely an outlier, but for me, it has its benefits.

[@anarey-oktay2683]

As someone who’s highly allergic to mosquito bites, Benadryl helps me sleep through the night without the itch waking me up.

[@jonathantran7102]

I'm... Not sure how to feel about this LOL Why not just use a mosquito net?

[@NancyW726]

My husband, who was diagnosed at age 53 with Fronto Temporal Dementia, was born in 1956 and had extreme allergies starting as a young child. He was put on strong antihistamine drugs like benadryl and was on them his whole life. He changed to the newer type of antihistamines like Claritan when they became available. I am convinced those medicines like benadryl caused his dementia - because he was on them consistently for so many years.

[@ItsMeNJC]

I’ve been taking diphenhydramine and promethazine HCL for years for insomnia. This video has opened my eyes - I thought they were entirely harmless, being available OTC without a prescription. Thank you.

[@Slurrberry]

Ignorance really is bliss huh? I do a deep dive into any substance i take, be it recreational prescription or just otc. Also you must not be in the US because promethazine is prescription only and since its 1/2 of codeine cough syrup (aka Lean) they only prescribe it in minimal amounts

[@JKHTX]

We can get a lot of drugs otc in the US that are prescription only in other countries or not available

[@AdultingsHard]

Depends on the situation. I have to eat antihistamines for my mast cell disease and Benadryl is the only one that can pull me out of a Mast cell flare up, other than eating a handful of newer antihistamines. Luckily i dont have to eat benadryl often but without it i could literally be dead right now. I hope Dr. Mike puts in a note so people dont just stop eating it if they NEED TO.

[@0nly0NE.]

I'm not sure there is a single medication out there that is entirely harmless. Everything has potential side effects and some of those side effects can show up with long-term use.

[@GmmBeast]

If a medication has no side effects at all, it's not real. Any medication that actually works has side effects, some more severe than others. Always ask your doctor or look up the side effects!

[@stephaniem8278]

Unisom soft gels are diphenhydramine, but the tablets are doxylamine succinate. I am glad I saw that and got curious because it led me to do more research and it turns out doxylamine is a stronger sedative than diphenhydramine. I only just now realized I shouldn’t be taking Unisom every night (my doctor seemed to be okay with it? She even told me I could take both in the same night). I have only taken it for five months, but I will exercise more caution and use both medications less frequently from now on. Thank you for the work you do, Dr. Mike.

[@crystalgaming12]

3:25 skip ad

[@jacquelinemilom4164]

I been taking Zyrtec for years anyways. Last time I took Benadryl was when I broke out in hives recently. I guess it’s good I rarely take it. Love your truth or scare videos.

[@KathleenPatterson-u6y]

I've been told not to take it. I have COPD.

[@DrippiBean]

cool

[@vidhoard]

Another potential causation is that people who have the conditions that require anticholinergic medications have a higher risk of dementia for some reason.

[@MichaelHorstmann]

Do this for black mold! Everyone on tiktok and Instagram is saying its the cause of all their obscure ailments. Is it that dangerous? Do people need to detox from it? Or is it just another allergen.

[@joemck85]

At least if it's that kind of black mold, it absolutely is nasty stuff. Apart from the allergic reaction to the spores it makes mycotoxins that affect you.

[@Unknown_Genius]

Yes, black mold is toxic, especially if it's one of the more toxic sorts - the mycotoxins can cause damages on multiple organs (lungs, neversystem and so on), not to say it's generally poisonous an if you got it in your home it should be taken care of properly asap. In fact, here landlords here absolutely have to make sure that appartments are clean of it, if there is cases it'll have to get removed and afterwards it'll be tested if it comes from wrong ventilation (essentially error of the party living there), construction damages on the house (which have to be resolved immediately if it's the case) or just an unlucky case that may happen - which also goes to the degree of landlords actively having to lower rent if issues occur.

[@falconinflight6235]

Excellent insight presentation

[@monkeyflower3851]

I seem to be really sensitive to antihistamines. One Benadryl will make me a zombie for at least 12 hours. What's weird is Claritin is even worse for me. One Claritin will make me an unproductive human for a good 24 hours. So I just avoid antihistamines completely unless I'm having some kind of allergic reaction that's really causing me problems. Normal seasonal hay fever, I just live with. It's not debilitating, just uncomfortable. If I do feel like I need some help, I take half a Benadryl. That seems to reduce the allergy symptoms just fine, and doesn't zombify me.

[@alphakowaclips]

That's side effects, not allergic reaction 😅

[@evad687]

Have you tried fexofenadine, like mentioned in the video? That’s an anticholinergic side effect that’s separate from the antihistamine effect

[@cnurenasue]

I took Benadryl when it was prescription. I was allergic to everything including my own bacteria. I took allergy shots for years. Once, I was given shot 10 times above the dose. I broke out in head to toe hives. I was told to take Benadryl and get to the urgent care as soon as possible. Today, I only take Benadryl for hives.

[@Personall-v6n]

Benadryl has never made me sleepy. I don’t know why, I just don’t react to it that way 🤷‍♀️

[@barbaravyse660]

Same here. Even narcotics given in the hospital make me doze off for a couple of minutes and then I’m up all night long!

[@Jennifer-nz2ss]

I've taken it for 64yrs. No effect. We are used to it?😢

[@MomtoaFullHouse]

My daughter and I both have no sleepy reaction to Benadryl, although it does reduce the histamine response, so that's good! With my daughter she was actually unable to sleep until it wore off. Long night for her!

[@pinkbigfan3845]

Ground News now DOWNLOADED. I LEARNED A LOT. THANK YOU SO MUCH DOCTOR MIKE. ❤❤🎉🎉😊

[@Exvinnittyy-CC]

W Mike fr, love this guy.

[@amytran7464]

The way you explained everything makes sense! Thank you for the video!

[@goodnotgreat1746]

Unhealthy hmmm I don’t know. But a vessel to meet the hat man…definitely

[@Russkellington]

The shadow people beckon.

[@sopiegut]

bro already forgot the video😭🙏

[@eschelon.videos]

Class of O'9: The Flip Side reference

[@TheTripleAce3]

​@@eschelon.videosbest part of that game right before one of the worst.

[@Kaenightowl]

I only take Benadryl when I’m in the ER with a severe migraine episode, never for allergies. The doctors in the ER usually prescribe it with Reglan/Torodol, and Zofran. When you’ve been awake for several days with a migraine bc you are in need of sleep anyway.

[@PhrygianDominant292]

Hey Mike! Amazing video and very informative! Could you please make a video about long term finasteride usage for hair loss, would be really interesting to watch.

[@maryhamric]

There is a small study out there that showed that Benadryl was efficacious in preventing leg cramps at night. As a result, I have taken it most nights for the past year and have had no cramping (when before it would happen every three weeks or so. VERY painful). But this makes me rethink my strategy.

[@RiverCrockett-in7bg]

Maybe you could try magnesium instead.

[@maryhamric]

@@RiverCrockett-in7bg I have. Doesn't work that well except when I actually have a cramp. It's not a good preventative for me, at least.

[@RiverCrockett-in7bg]

@@maryhamric Sorry to hear it, Mary.

[@jlaurelc]

7:10 There are only better options if the other options work. 😭

[@stephaniem8278]

Right? Loratodine increased my insomnia and made my nasal passages so dry. Cetrizine works most days, but if it’s windy or there is any pollen at all it’s basically useless. Fexofenadine also dries out my nasal passages and doesn’t seem to work if my nasal passages are blocked even a tiny bit. Oxymetazoline works great but can only be used once or twice a week. At this point I think my weather guide should come with an allergy medicine roulette wheel. Lol

[@ryanrafanan2852]

Thank you Dr. Mike for helping me be aware of Benadryl. I've been taking it to help me sleep at night bc melatonin just doesn't work for me anymore. But I'll def ask my primary care doc for an alternative.

[@may]

We love you Doctor Mike!

[@AdultingsHard]

Indeed, many many years of loving doctor Mike. I dont think anything Dr. Mike could do would make me hate him. One of my favorite things about him in the past is that listens to people when they cross analize his fact sometimes and fixes problems if he makes them too!

[@nikkilove4584]

I take Claritin everyday but not for sleep. I hope that one is okay! It helps me a lot.

[@Jelly.Fish1212]

Can you react to more hockey injuries? Love these vids!

[@yonimortier]

Thanks ! Taking diphenhydramine as sleep aid sometimes. Taken with from the US 🙈. It’s also an active ingredient in ‘Dormidina’ freely to get in Spanish pharmacies.

[@wheeliegirl1630]

Kaiser hospital in Irvine CA would give me Benadryl in my IV and I hated it. The last time the nurse did not even tell me he was giving it to me. I would have told him not to. And why? Why give it to an ER patient? To shut me up and make me sleep? I disliked the sudden onset of drowsiness that made me feel like I was falling into spiraling tunnel.

[@syrena911]

Why did you go to the ER?

[@heathercole9851]

I have MCAS, and benadryl is the go to in the hospital for major allergic reactions. I used to take remicade, a very potent IV medication, and I was allergic go it. They'd do IV benadryl and IV steroids at the same time to prevent the reaction. When my face swells shut due to an MCAS reaction, the only thing that touches it is massive doses of steroids and benadryl, plus Zyrtec. Benefits and risks, always talk to your doc about the benefits and risks of meds. For me, benefits far outweigh the risks, but they may not for others.

[@cluelesshh]

Hey. My dad has a chronic illness, and i'm not sure what- but tonight he collapsed, hit his head, and passed out slumped over his desk on the ground, while throwing up. My mom called the ambulance and I did my first chest compressions on him. I was so shaky but I managed. Then the ambulance arrived. I don't know if he is okay. I am 13 years old, but mature for my age. Please help me pray for him. EDIT: He passed away.

[@lf4061]

So sorry sweetheart. Stay strong, the memories of the time you had and the things he taught will always be with you. Do not be afraid to share your feelings, others may understand.

[@maritoh.6710]

I'm so sorry for you! You did everything you could to help believe me when I say he loves you for trying so hard and he's proud of you.

[@Preinstallable]

I'm sorry for your loss. I will pray for your father's journey to the sky. 🕯️

[@catherine8770]

Praying for you and your family. They must be proud of how brave you were in the face of danger. May God comfort you as you grieve.

[@huuthangduock10a77]

As a student, Dr Mike makes my med studies become an interesting journey. Randomly pickup knowledge that save my time ❤

[@paulprovenzanotelejug7877]

Dramamine for seniors on a cruise should be evaluated

[@ngcf4238]

I have never been on a cruise but that certainly does sound like a bad situation to set yourself up in. I would assume the concern is falling off / falling down on the cruise ship?

[@paulprovenzanotelejug7877]

@@ngcf4238 no, most Dramamine brand is now meclizine, a first gen antihistamine linked to memory issues like Benadryl

[@alexbireta4668]

AFAIK, dramamine is just diphenhydramine with a caffeine-like stimulant to combat the drowsiness, the anticholinergic properties of the DPH is what reduces nausea

[@paulprovenzanotelejug7877]

@@alexbireta4668 most Dramamine has been changed to meclizine. They do sell the original formula still. But at airports I only saw the meclizine.

[@billythao8669]

Havnt taken benadryl for years. Was my go to previously due to the effectiveness for severe seasonal allergies. I just wear a mask now. 90% effective.

[@Uncle_Smidge]

My useless superpower is an immunity to the drowsiness of Diphenhydramine. Found out on accident after I used it for an eye rash and drove myself to the clinic, as bright-eyed and bushy-tailed as ever. The doctor joked that he wanted to put a biopsy of me under a microscope. 🤭

[@dayeti6794]

Same here. Doctors don’t believe when I say it doesn’t make me drowsy, it makes me more alert.