Jeff Volek, PhD -- Discussion on Ketogenic Diet for Dyslipidemia & Metabolic Syndrome

Jeff Volek, PhD
Professor
Department of Human Sciences, The Ohio State University
Jeff Volek, Ph.D. Dr. Jeff Volek is a registered dietitian and professor in the Department of Human Sciences at the Ohio State University. For the last two decades he has been performing cutting edge research elucidating how humans adapt to diets restricted in carbohydrate with a dual focus on clinical and performance applications. His work has contributed to the existing robust science of ketones and ketogenic diets, their use as a therapeutic tool to manage insulin resistance, plus their emerging potential to augment human performance and resiliency. This research indicates that that well formulated ketogenic diets result in substantial improvements in insulin resistance and the myriad of cardio-metabolic biomarkers associated with metabolic syndrome, including favorable changes in fatty acid composition and saturated fat metabolism, cholesterol and lipoprotein profiles. He has also performed seminal research on a wide range of dietary supplements (e.g., creatine, chromium, whey protein, caffeine, carnitine, HMB, etc.) that can augment performance and recovery. He has accumulated an enormous amount of laboratory and clinical data as it pertains to biomarker discovery and formulation of personalized, effective and sustainable low-carbohydrate diets. His team is currently exploring the role of nutritional ketosis induced by diet and/or supplements to: 1) reverse type-2 diabetes, 2) alter gut microbiota, 3) favorable impact tumor metabolism and health outcomes in women with advanced breast cancer, and 4) extend human physical and cognitive capabilities in elite athletes and military personnel. Dr. Volek has secured several million dollars in research funds from federal sources, industry, and foundations. He has been invited to lecture on his research nearly 200 times at scientific and industry conferences in a dozen countries. His scholarly work includes 300+ peer-reviewed scientific manuscripts and five books, including a New York Times Best Seller.

[@chloe7seven22]

Thank God for our Dr. Tim Noakes here in South Africa. He also talks very highly of you. All I can say is this: I have type II (A) Heterozygous Familial Hypercholesterolemia. Both my sons inherited the disease. My mom is the carrier and she is now going onto 87. She only went onto meds in her 60's and immediately could not tolerate statins so then went onto fibrates, now on nothing. BUT, my sons I fear for. My eldest son recently had quintuple bypass surgery very hastily (had NO heart attack, so his heart muscle is normal. Didn't know quintuple bypass existed. Thoracic surgeon had never done this on such a young person. So I went onto keto with my 13 - 14 total cholesterol and 2.? trigs. After a month (BUT I never stopped taking fibrates low dosage) - everyone waited for me to drop dead. The fibrates could never get me lower than 8.2. My GP phoned and said it was as if my results did not belong in my file. My trigs were now 0.7 and total of 6.3 (NEVER since birth had it gone lower than 7.5) Thank you for this talk - I think Keto is the biggest breakthrough of the modern time.

[@123ofd]

305 total cholesterol / Hdl 150, vldl 12. Yay. Almost 60 and I'm happy with my ratios...great talk. Thank you!

[@michellemcquade2550]

This was very helpful for understanding the science behind the fat adapted keto life. I was able to reverse metabolic syndrome, type 2 pre-diabetes, high cholesterol, MS symptoms by changing my body to eating only real food low carb then hCG and I now live LCMPHF lifestyle as well as losing 88# and keeping it off for 6 years. I am blessed every day to be able to help others change their health destiny (as well as their clothing size) every single day at my weight loss clinic. Thanks for spreading the word. I will be recommending this video to my clients.

[@LordJasonKing]

Lcmphf?

[@amplifiedhealthnow7100]

I just want to say thank you Dr. Jeff Volek for your work and for validating my lifestyle. I don't feel I will ever have to defend it or question it ever again.

[@toddstuder7388]

I follow everything that Volek presents on. I've been on a ketogenic diet for about 9 months and it has had better results in all areas than I could have ever believed. I expect that I will be on a ketogenic diet for life, but there is so much variation in what is promoted for ketogenic diets. The basis of my is whole foods (largely all non-processed). Thanks so much Jeff....

[@carrollhoagland1053]

Congrats ... I agree ... nice to eat butter again ... and of course greens and bacon ... just have to find grass fed stuff ...70 Going On 100

[@bru1015]

Todd S, you go girl!

[@krazikrafter4516]

Todd Studer is

[@wishnudwimarendra3682]

how's your uric acid serum todd? is it high after at least 1 year on ketogenic diet?

[@alphacause]

Thank you for the upload. Jeff Volek always provides fascinating presentations.

[@alexpeikary]

Thank you for the upload.

[@WahineInTN]

Recently got a blood panel done. Told my doc that I recently lost 40 lbs from Keto diet and IF. She asked is was eating butter, sour cream, etc. I said absolutely. She was horrified. Then my results came back…everything normal. She had the “ I don’t get it” look on her face. I’m sure she was expecting my ldl and triglycerides to be off the charts bad.

[@Jefferdaughter]

Volek seemed not to understand the first question, about limiting food intake to a certain window of time per day. This is often called 'intermittent fasting', but the word intermittent does not indicate that this fasting happens within a 24 hour daily cycle. Dr. Mercola calls this 'peak fasting', and recommends that people eat within a 6 to 8 hour time period each day, which results in a 16 to 18 hour daily fast.On a very low carb high fat diet, this becomes pretty easy to do, a 'painless' way to help our bodies to burn fat.

[@carrollhoagland1053]

Ref Dr. Panda ... TRF, Time Restricted Feeding, and the Circadian Rhythm clocks all bodily functions ...70 Going On 100

[@lindamcneil711]

He is pretty aware of it... you are listening to one talk of 20 years of work.

[@leahlandi143]

I want him to review my bloodwork, after being on Keto for a few years. He looks a lot deeper then regular Drs.

[@presentlyhappy]

Love the luxurious food idea!

[@ChangeMatt]

I'm struggling with 16:1 (omega 7) which I assumed was good because it aided insulin sensitivity; Jeff's saying its a marker for the opposite - anybody any clues?

[@almacolic]

I get up at 5 am just to watch this.

[@protoword10]

Ja nisam, ali da sam morao, rado bih!

[@gigisgiftofgab]

early bird catches the worm

[@SamuraiBatgirl]

What was asked at about 44 minutes? I couldn't really understand her.

[@sharpienails]

Wonder what sugar companies will try next , because of people catching on about Toxic sugar. Maybe put fat back in . But if they do it surely won't be the healthy kind ! More veg. oil & corn junk ..

[@ReeImagined]

I'm with you, sharpie. This country uses the cheapest, nastiest fats obtainable, because all you have to do it read the labels on all products. It's all about profits. We have to make all our own foods now. And make our own choices.

[@sharpienails]

I know Right .. Then you have the organic food prices Crazy expensive , even if people want to eat healthy :( Well that's why they make the Junk cheaper , to keep us sick . So the DR's & Drug companies can make money on us . Like a Bad "soap opera" I picked a Name for it .. "As Monsanto Turns The World " Ha ha ha

[@paulam1596]

What did he say about saturated fat and Macadamia nut ?

[@chetroman6196]

The point he was making is that Palmitoleic Acid is not very prevalent in the foods we eat, except in Macademia nuts, i.e. there are higher amounts of it in Macademia nuts. He doesn't make a judgement whether you should eat them or not. The reason he points this out is that since we don't eat foods high in Palmitoleic Acid and, since the liver uses carbs to create Palmitoleic Acid (lipogenesis), then high amounts of Palmitoleic Acid in our body is a good marker of insulin resistance or carb intolerance. And that higher proportions of Palmitoleic Acid found in our body are associated with: o Obesity o Hypertryglyceridemia o Inflammation o Metabolic syndrome o Type-2 diabetes o Coronary disease o Hear failure o Incidence & aggressiveness of prostrate cancer

[@paulam1596]

+Chet Roman thanks Chet .. I eat mac nuts as one of my fat bomb through the week ..( although I know Stephanie Person don't recommend it) .. So I wanted to see what he had to say about it..

[@zoemelvin1850]

5 years keto 💪💪💪😁😁😁

[@vegetablepolice]

Bacon and butter? Guy is a lunatic lol. You can do plant based low carb, much healthier in my opinion. Backed by science ;)

[@carrollhoagland1053]

Sorry, there is no science to support you idea, veggies are good, but not enough for health ... 70 Going On 100

[@vegetablepolice]

Carroll Hoagland There's plenty. Diet and cholesterol levels: www.ncbi.nlm.nih.gov/pmc/articles/PMC3603726/ www.ncbi.nlm.nih.gov/pmc/articles/PMC1764970/ www.ncbi.nlm.nih.gov/pubmed/17364116 www.faseb.org/portals/2/pdfs/opa/11419_faseb.pdf www.ncbi.nlm.nih.gov/pubmed/10704618 www.ncbi.nlm.nih.gov/pubmed/16904539 www.ncbi.nlm.nih.gov/pubmed/21122648 www.ncbi.nlm.nih.gov/pubmed/16250264 www.ncbi.nlm.nih.gov/pubmed/1534437 www.cspinet.org/nah/pdfs/covermay2014.pdf www.ncbi.nlm.nih.gov/pubmed/24484612 www.ncbi.nlm.nih.gov/pmc/articles/PMC1312295/ www.ncbi.nlm.nih.gov/pubmed/313701 www.ncbi.nlm.nih.gov/pmc/articles/PMC2125600/ www.ncbi.nlm.nih.gov/pubmed/7019459 Eco Atkins study www.ncbi.nlm.nih.gov/pubmed/19506174 A saturated fatty acid-rich diet induces an obesity-linked pro inflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome. www.ncbi.nlm.nih.gov/pubmed/19828712 Effect of a single high-fat meal on endothelial function in healthy subjects. www.ncbi.nlm.nih.gov/pubmed/9036757 A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. www.ncbi.nlm.nih.gov/pubmed/15983191 Effects of a high-fat meal on pulmonary function in healthy subjects. www.ncbi.nlm.nih.gov/pubmed/20165863 Low-carbohydrate diets and all-cause and cause-specific mortality: two cohort studies. www.ncbi.nlm.nih.gov/pubmed/20820038 Lipotoxicity: effects of dietary saturated and transfatty acids. www.ncbi.nlm.nih.gov/pubmed/23509418 Low insulin like growth factor in vegans. www.ncbi.nlm.nih.gov/pubmed/10883675 Heart disease risk factors predict erectile dysfunction 25 years later: the Rancho Bernardo Study. www.ncbi.nlm.nih.gov/pubmed/15093875 Erectile dysfunction prevalence, time of onset and association with risk factors in 300 consecutive patients with acute chest pain and angiographically documented coronary artery disease. www.ncbi.nlm.nih.gov/pubmed/12932937 Development of Symptomatic Cardiovascular Disease after Self-Reported Adherence to the Atkins Diet. www.andjrnl.org/article/S0002-8223%2809%2900452-0/abstract Reduced risk of colon cancer following vegan diet www.ncbi.nlm.nih.gov/pubmed/1552366 Pollutants found in meat: www.ncbi.nlm.nih.gov/pubmed/18410965 www.ncbi.nlm.nih.gov/pubmed/9504980 www.ncbi.nlm.nih.gov/pubmed/15833488 www.ncbi.nlm.nih.gov/pubmed/21106919 www.ncbi.nlm.nih.gov/pubmed/21195558 www.ncbi.nlm.nih.gov/pubmed/17450232 www.ncbi.nlm.nih.gov/pubmed/21364465 www.sciencedirect.com/science/article/pii/S030881460700221X Methionine is dangerous: Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment. Guess what's high in sulfur containing amino acids? Animal products! www.ncbi.nlm.nih.gov/pubmed/22342103 www.ncbi.nlm.nih.gov/pubmed/21836027 www.ncbi.nlm.nih.gov/pubmed/18252204 www.ncbi.nlm.nih.gov/pubmed/18789600 www.ncbi.nlm.nih.gov/pubmed/15955547

[@heathermcmullin5071]

Vegetable Police u r crazy

[@Jefferdaughter]

Some commenters are obviously lacking sufficient cholesterol, Omega 3 fatty acids, B12, and other key nutrients for optimal health and brain function, eh?

[@carrollhoagland1053]

Indeed ... but anything is better than the SAD, which referenced high carbs ... there is NO known Carbohydrate Deficiency Disease, whereas this is not true of Fats and Proteins ...