Skin Adnexal Tumors 101: A Basic Approach for General Pathologists

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Күн бұрын

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@JMGardnerMD 3 жыл бұрын

Excerpt from "Dermatopathology Pearls for Head & Neck / Oral & Maxillofacial Pathologists" (full video: kikoxp.com/posts/6020). See our free paper for more info: pubmed.ncbi.nlm.nih.gov/30638401/. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

@harshagajjar2889 25 күн бұрын

Thank you Dr Gardner for practical insights and approach.

@wolpumba4099 4 ай бұрын

*Skin Adnexal Tumors 101: A Basic Approach for General Pathologists - Summary with Timestamps* * *(**0:17**) Categorization:* Skin adnexal tumors can be broadly categorized as: * *Sebaceous Lesions:* Tumors showing sebaceous differentiation (presence of sebocytes). * *Sweat Gland/Duct Lesions:* Tumors exhibiting sweat gland or ductal structures. * *Hair Follicle Lesions:* Tumors with features suggesting origin from or differentiation towards hair follicle structures. * *(**1:28**) Key Histological Features:* * *Sebocytes:* Identified by clear, sharply circumscribed vacuoles that often indent the nucleus (presence of lipid). * *Sweat Ducts:* Sharply demarcated spaces or tubules within the tumor, sometimes lined by a distinct layer of cuboidal cells. * *Hair Follicle Tumors:* Often composed of blue basaloid cells with peripheral palisading, accompanied by a characteristic, more cellular stroma. Presence of papillary mesenchymal bodies is a strong clue. * *(**8:52**) Examples of Tumors Discussed:* * *Sebaceous:* Sebaceous hyperplasia, Sebaceous adenoma, Sebaceoma, Sebaceous carcinoma. * *Sweat Gland/Duct:* Poromas, Hydroadenomas, Spiral adenomas, Cylindromas, Syringomas, Sclerosing sweat duct carcinoma (Microcystic adnexal carcinoma), Syringocystadenoma papilliferum, Chondroid syringoma. * *Hair Follicle:* Trichofolliculoma, Trichoepithelioma, Trichoblastoma, Pilomatricoma. * *(**41:17**) Important Diagnostic Considerations:* * *Malignancy:* Recognizing features of malignancy such as cytological atypia, infiltrative growth patterns, and atypical mitotic figures is crucial. * *Overlap:* Adnexal tumors can have overlapping features, making diagnosis challenging. * *Clinical Correlation:* Clinical presentation and history are important for accurate diagnosis. This summary provides a basic overview of the content covered in the video. For a more detailed understanding, it is recommended to refer to the full video and the accompanying paper mentioned in the description. Remember, this information is for educational purposes only and does not constitute medical advice. I used gemini-1.5-pro-exp-0801 to summarize the transcript. Cost (if I didn't use the free tier): $0.12 Input tokens: 30598 Output tokens: 970

@AK-ct8bb Жыл бұрын

Thanks Dr. Gardner this was really helpful in understanding and preparing my presentation on approach to skin adnexal tumor. Your research paper also very useful. I highly recommend it.

@kellyparmer67 Жыл бұрын

My sister had an adnexal skin cancer of a sweat gland around the ankle. Taken off over 15 years ago. She was told it is extremely rare.

@nicolagray6812 2 жыл бұрын

Thank you from dermatology registrars (residents) at Stellenbosch University in Cape Town, South Africa!! 🇿🇦

@JMGardnerMD 2 жыл бұрын

Thank you for the kind words! Sending my best wishes to you and all of the registrars at Stellenbosch! I hope to visit South Africa one day!

@swathij4417 Жыл бұрын

Hello Dr. Jerad, I'm a pathology resident from India and I find your videos very useful. It's mostly self-directed learning here but you teach me a lot! Thank you so much! Could you please add some points about the clinical and gross appearance of the lesions too (with pictures) so we can correlate with the histopathology? Thank you!

@JMGardnerMD Жыл бұрын

Thanks for the kind words. I try to add clinical and gross path when I can. But for my short video clips (which mostly come from my rapid review sessions for my derm residents where i try to cover 25 cases in 1.5 hours) there just isn’t enough time to go into those details. I have some gross and clinical pics listed on my Kiko index. Just search those pages for “gross” or “clinical”. Will be adding more in future: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

@swathij4417 Жыл бұрын

Thank you very much for taking the time to reply! I'm honored! I'll check those out, Thank you again! 😁