Diabetic nephropathy - Mechanisms | Endocrine system diseases | NCLEX-RN | Khan Academy

[@jacquelinecook5613]

My oldest son is in his early 20's and he has type 1 diabetes. But thank God for this piece of article kzbin.infoUgkxVYhghKWmrUgXARZ_ydZTvmmcrw5L0I5i At first he thought he had the flu and was lying down on the bed for three days until his sister took him to the hospital. They took his blood and it was 600. What I do not understand is how he could have gotten it, since no one in the family has it. But he is winning the battle now. This is good stuff.

[@fayyazyounus1585]

DM causes hyaline arteriosclerosis in the efferent arteriole causing increased filtration. Very well explained. Thank you

[@HabibUrrahman-vy6dh]

So basically what you are trying to say is that's responsible for Hypertension?

[@mariac7394]

Thank you for going into great detail!

[@lifeofachristiannursingstu9498]

Thank you so much. I finally understood after a week of reading and lectures.

[@marconeill2229]

Clearest explanation of CKD and its cause! Thanks! Would love to see your "powers of explanation" used to outline the latest research into reversing CKD or better treating it? (eg SGLT2, GLP-1 etc) - the current explanation of which I find impenetrable as a lay person!

[@annawright4545]

Thank you, so much. To me it was clearly hearable (in reference to another comment bellow) and I do appreciate that you did not gotten lost in details you have presented in other VDOs (about the damage mechanism).

[@drhouse9801]

the reason for efferent arteriolar vascular lumen narrowing is not vasoconstriction , it is hyaline artriolarscelerosis

[@KloiKoch]

Thank you for this great detailed explanation! Even for me, who is not a medical student, it is easily understandable!

[@bishal-kd2jq]

Thank you so much i finally understood the concept 🙏🏻

[@holkangel]

This is a beautifully done, clear, concise and well illustrated. Thank you. I do have some critique still - I could barely hear you. Also, I think you did not really explain the pathological changes which happen in the arteries and arterioles of the kidney (as in the lesions of these)... some lesions which lead to glomerulosclerosis? Or maybe you did but without the nomenclature which is used? :(

[@aleksandarmirchev5792]

hi everyone ,if anyone else wants to discover what is a kidney disease try Franaar Healthy Kidney Formula (do a search on google ) ? Ive heard some super things about it and my brother in law got cool success with it.

[@ygatesatellite4964]

Not certain about the points made but ,if anyone else wants to uncover disease of the kidney try Franaar Healthy Kidney Formula (do a search on google ) ? Ive heard some amazing things about it and my m8 got amazing success with it.

[@yasminfaria170]

Dominique রবিদৃনাহ সঃগিত

[@georgiosantonopoulos7893]

Appreciate Video clip! Excuse me for the intrusion, I am interested in your initial thoughts. Have you thought about - Trentvorty Perfection Kidney Theorem (Sure I saw it on Google)? It is a great one off guide for improving kidney function without the hard work. Ive heard some pretty good things about it and my buddy at very last got great success with it.

[@zeinabghamlouch9920]

Very well explained and illustrated, thank you so much this was really helpful

[@RoshanLovesall]

Very Clearly explained the concept. Really Good. Continue the good work

[@haythemayachi3384]

this is eactely what i was seraching for !! thank you very much :DD

[@danielatomescu3487]

hey ,if anyone else wants to uncover natural cure for chronic kidney disease try Franaar Healthy Kidney Formula (just google it ) ? Ive heard some interesting things about it and my brother in law got excellent success with it.

[@sergioescalona62]

Cheers for the Video clip! Apologies for chiming in, I am interested in your thoughts. Have you heard about - Zeyames Wonliver Breakthrough (do a search on google)? It is a great exclusive product for discovering the simple way to end diabetic nerve pain and neuropathy without the normal expense. Ive heard some super things about it and my work colleague finally got amazing results with it.

[@borafrusciante3328]

Great video, good explanation, but i could hardly hear her voice :(

[@sandeshsharma3560]

his tune

[@theelitenurses]

Use captions

[@agoogleuser4354]

It's a guy...a very effeminate guy.

[@brudforce]

Please provide literature source for activation of RAAS in diabetic nephropathy!

[@Ledeluz]

I'm really scared since I was diagnosed with dm and checking out what will my end game if it really get worse. I know it's my fault but I really want to fight since I didn't achieve anything in life yet and I'm already 34. I hope I can finance continually my medications to avoid these complications.

[@leavinoneday]

Wow I really like how u explain

[@jalalalakhras4113]

Thank you very much man,, very very helpful

[@arunanirudhan1812]

Thank you very much for this mind blowing information.I have one question.....you described about RAAS,its mechanism is vasoconstriction in efferent arteriole when there is renal perfusion right..Then why it’s get activated during increased glomerular filtration¿

[@fahadafridi8173]

Watch at 7:10 he explains that the etiology is not known but they think it might have to do with the fact that hyperglycemia some how activates RDA system

[@annawright4545]

I see you have asked this 3 yrs ago - but I am here just now and taking a chance to have a reason "speculated" out on it: perhaps this is a defensive mechanism where the kidneys choose the less worse scenario by trying to stabilize the post glomerular (afferent) blood-pressure and to "push back" against the increased filtration. This - if I think of kidneys as organs actively regulating the hydraulic side of the main blood pressure. AND/OR: it is a direct and swift way to flush out excess glucose (since the Renin is triggered by high blood sugar in a direct and immediate short circuit in the kidney).

[@HabibUrrahman-vy6dh]

@@annawright4545 the basic question that I have is how does hypertension develop from diabetes mellitus although he mentions it as saying that it's a comorbidity ?

[@sbusobantu1490]

Thank you so much

[@jean.lucstrack8706]

Brilliant explanation

[@PaulusLeThien]

Thx! Very well explained!

[@sopiaahmad7795]

thanx for advice,God bless you

[@skasifali8627]

It is very helpful 😍

[@Habe111]

This is peeeerfect, thank youu

[@clairemonaghan9684]

Fantastic! Thank you!

[@university2775]

Please increase ypur volume while recording. Despite being on maximum volume on both headphones and speakers, your videos can be hardly be heard more often than not.

[@lifeisbeautiful7047]

Perfect 👏👏👏

[@Haipha99]

wonderful. thank u

[@HafizahHoshni]

Your videos are very helpful. Thank you :D

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[@Zenith00011]

Can someone please explain why there is a decreased renal perfusion when there is hypertension? Thank you.

[@sreynethpav2365]

best working .and i would like to see diabete neuroparty .can you make it?

[@josejoao1621]

Amazing!

[@unknownperson-pt7bf]

How a wonderful video 🌹🌹

[@abeera6812]

What a wonderful video*

[@ofitlhileruxralenyena1230]

perfect.. God bless you.. this is exactly what I was looking for

[@samzu9626]

hi thanks alot . why do GFR decrease in the stages of DKD

[@pou2965]

Amazing🔥

[@memobayomi]

Brilliant

[@kishoremazumdar2004]

I think RAAS reponds to low blood pressure. It leads to constriction of afferent arterioles not efferent arterioles so that it can decrease the GFR and maintain the volume of blood and can subsequently maintain the blood pressure. You have explained RAAS increases GFR. Can you elaborate a bit

[@deephc]

yes

[@ronnynoneofyourbusinessgoo7892]

You are too fast man!!! Speed controls on youtube app SUCKS. Google is the 👿 destroy them

[@agoogleuser4354]

This video would be great if the voice was louder by 200%...

[@valsartanay7117]

Thanx 🫶🏻

[@somewherealone226]

Perfecto 👌

[@CarolynDenison]

I wish I haden't sen this. My doctor called my husband today. I'm waiting for them to call me. I missed his call earlier. Blood work a few day's ago. I have all the symptoms of stage 5 kidney disease. Having extreme pain in my back, and can't stand up. I got a bad bad feeling something bad is up. I'm going to bed.

[@nishey94]

Carolyn Byrd did you find out what it was?

[@binitamakhim9905]

You are not connecting your explanation to the diabetes.... I was expecting how hyperglycemic state metabolism causes changes in microvasculature

[@mateuspereira3802]

Great video, but hearing the narrator whispering was sorta annoying.

[@Safestreet]

Did anyone hear him say "efferent arteriole" -twice??!

[@donraquel]

😮

[@D3cker1]

You can speak up to the mic you know??

[@leo-lj1to]

you don't talk about AGE

[@drtanveerahmed3373]

Not clarified properly...

[@sandeshsharma3560]

im thankful for the video..but this is not a makeup tutorial man..just sayin

[@anastasia.2007.]

The lecturer almost whispers. What's the point of speaking in such a quiet voice? You don't want to wake up your neighbors?

[@kabitapun6437]

LOL. I can hear him though :D

[@azersamaali2016]

Thanks for the Video! Forgive me for the intrusion, I would love your thoughts. Have you tried - Chireetler Avoiding Diseases Rule (search on google)? It is a great one off guide for learning how to stop kidney damage minus the headache. Ive heard some unbelievable things about it and my buddy got amazing results with it.

[@Valentina_-lw9ui]

Winner of a video, been searching for "how does diabetes increase risk of heart attack?" for a while now, and I think this has helped. Ever heard of - Piyatalie Breathtaking Precedence - (do a google search ) ? It is a great one of a kind guide for discovering how to get rid of type two diabetes minus the normal expense. Ive heard some unbelievable things about it and my co-worker got excellent results with it.

[@ronnynoneofyourbusinessgoo7892]

And you are too quiet too

[@stephenokwori1882]

My heart just keeps thanking you and thanking you Dr Igudia for all you have done for me, you gave me your words that you could heal any sickness or disease, thank you for permanently curing me of my diabetes disease you are amazing.

[@salikusmani4665]

Why do you update videos with so less volume? Plz dont upload them and spoil our mood....