Diabetic Nephropathy - Nephrotic Syndrome - Kidney Pathology

[@MedicosisPerfectionalis]

🌯 Endocrine Pharmacology Course: www.medicosisperfectionalis.com/products/

[@GustavoDantas]

A. Mild to moderate vasoconstriction of the efferent arteriole (angiotensin II) increases glomerular hydrostatic pressure, resulting in increased filtration across the glomerulus. This resulting increase in GFR also increases the clearance of creatinine, since the amount of creatinine that enters the urine is approximately equal to the amount that is filtered across the glomeruli.

[@husnainakhtar9222]

really enjoying my nephrology, mediocosis gives the perfect base, where my lectures & lessons in clinic complete the knowledge!

[@MedicosisPerfectionalis]

Thank you 🙏

[@lululewiss2063]

Thank you so much I was struggling to understand the lecture YOU SAVED THE DAY DOCTOR !!

[@MedicosisPerfectionalis]

My pleasure 😇

[@nikolamarkovic4845]

Hey, i got one advice for you. What about most common series. I found out pretty hard to find all most commons in one place and that term is pretty helpful. For example, you on hematology you can say most common cause of anemia, most common cause of low mcv, most common high mcv, most common cause of splenomegaly etc. Liver - most common cause of jaundice, most common cause of chirosis, elevated alp, elevated ast, ggt...

[@MedicosisPerfectionalis]

Great idea 💡

[@nikolamarkovic4845]

@@MedicosisPerfectionalis tnx, i mean you rarely find all most commons in one book, so it would be helpful if you could see it all in one place

[@MedicosisPerfectionalis]

I really appreciate you! Thanks for letting me know!

[@MedicosisPerfectionalis]

👨‍🏫 Nephrology Playlist: kzbin.info/aero/PLYcLrRDaR8_d7bEi4DvucO73N4N_1vvPk

[@josephakalonu1052]

Great job Dr. Medicosis I believe it is "Kimmelstiel not Klimmesteil. Keep up the good work. For the question, A

[@zainabalkshik4258]

higher than normal bc increase GFR so clearance increase. awesome way of explanation, thank you!

[@amalahmed5198]

Wow i get happy when i see notification comes from you channel

[@MedicosisPerfectionalis]

Thank you so much, dear :)

[@bekalumolla9173]

Great doctor From africa,Ethiopia

[@MedicosisPerfectionalis]

Thank you!

[@ghinacharafeddine]

Thank you from the bottom of my heart 💜

[@MedicosisPerfectionalis]

Thank you from my left ventricle!

[@user-ec1uy8jl3i]

Amaaaaazing !!❤❤❤❤❤Thanks you so much ❤

[@MedicosisPerfectionalis]

My pleasure 😇

[@KADETUL9]

Why is efferent arteriole affected in diabetic nephropathy and not afferent arteriole?

[@darshma8733]

i think because of angiotensin 2 activity on the efferent arteriole which make him more constricted

[@jean.lucstrack8706]

Transcription correction... Schoenlein Henoch purpura (1,59 ) Wegener synd (2,05) Aorta ( 2,37 ) Kimmelstiel Wilson nodule )3,55 ) osmotic (6,42 ) osmotically (6,50 ) Kimmelstiel Wilson (7,16)

[@AqsaSadiq-x6x]

Answer is A... Correct me if i am wrong .. Bcoz In diabetes,, NEG of efferent arteriole before the afferent causes the hyperfiltration and result in increased clearance of Creatinine..

[@drSJV]

Excellent video, thank you! ✨

[@MedicosisPerfectionalis]

My pleasure 😇

[@chrisrambo8142]

Well I think it's important to add I'm type 1 diabetic and have been since I was child. Diabetes will not cause any complications whatsoever if you keep your blood sugars under control and you don't get high blood pressure

[@mohammedamir7197]

Brillant pro Extra ordinary as always

[@MedicosisPerfectionalis]

Thank you ☺️

[@medicoexams6383]

Wowwwwww sooo precise 🙏

[@mohamedelhayek5789]

I love u bro .. u r a great doctor

[@MedicosisPerfectionalis]

Thank you so much 😊

[@TanTan-ch3vq]

Can you explain why the thicken basement membrane but a protein leak? It seems doesnt make sense, thanks

[@idea4022]

Thanks medicosis ❤

[@jolitrisha-vn6ms]

Hello! May I know which book you based your information on?

[@ajay997]

Nefrosave tablet used to treat Diabetic Nephropathy

[@alessiamelis7863]

Awesome job! Thank you so much

[@MedicosisPerfectionalis]

Thank you 😊

[@amarachikimberlyemeribe798]

When it's non enzymatic glycation in first aid and I'm wondering if he is throwing shades 😎😁 I always look for your video on any topic . Thanks

[@MedicosisPerfectionalis]

Haha 🤣 No, I am not throwing shades at them. I just saw this mistake made so many times by professors!

[@ng623]

@@MedicosisPerfectionalis "throwing shades" 😂

[@sohaibtorab4348]

Please ineed to know the mechanism by which mesangial sclerosis leads to protinuria

[@tiffanywelchhomesteadnmama5524]

What about taking Ozempic for the diabetes, hopefully leading to positive overall results?

[@zmzm.osman001]

A) Higher than normal. THANK YOU

[@drjoj9512]

Great explanation thank you so much 🌹🌹

[@MedicosisPerfectionalis]

My pleasure 😇

[@Yan-pg1rs]

Hi Medicosis, I have a question from MRCP that glomeruloslerosis happens in long term diabetes when HbA1C is normal as well, and apparently is the most common complication, could this be explained by hyperperfusion injury, or what is causing it?

[@berkesolak9985]

please more nefrology videos

[@MedicosisPerfectionalis]

Ok!

[@NesreenSari]

Amazing

[@helengauthier1382]

what is this sludge on the kidneys that causes diabetis

[@MedicosisPerfectionalis]

???

[@tausiftaz1000]

Your qualification Sir? Or you internist or resident?

[@MedicosisPerfectionalis]

Neither!

[@haochenvlogs]

@@MedicosisPerfectionalis😮😮 so you are just a medical teacher & a full time medical scientist? 😅

[@rekhakadam6393]

Brilliant. Thank you 🙏🏻 Higher than normal

[@MedicosisPerfectionalis]

Thank you!

[@ervayldrm4165]

what's the correct answer

[@john.the.beloved]

Higher than normal, because GFR is higher than normal.

[@paralleluniverse7581]

Perfect 👌🏼

[@احمداحمدالال]

Please if l use empagliflozincan I us ACE inhibitor

[@pratishthaojha9724]

I think there will be no change in Creatinine clearance.

[@cabdullahbihi1902]

Higher than normal since the GFR is increased.

[@Hiba-jq2ug]

Thank you so much,you are agreat doctor.💚💚 How can i find your papers?

[@MedicosisPerfectionalis]

Thank you so much 😊, Hiba! My notes are available to download on my website: www.medicosisperfectionalis.com/

[@centurytreehealtheducation3871]

Thanks for EVERYTHING, but especially the renal benefits of ACE inhibitors. Knew they were good for your kidneys, but now why. A big deal!

[@alexandraalexandru1669]

Awesome!

[@noorekhudagroup995]

Normal because of in early stages creatinine not increases

[@DoctorlifeinAustralia]

Hey you dont have GIT lecture dont you?

[@MedicosisPerfectionalis]

I have a short “hepatology” playlist.

[@napulse]

Dry water exists)))) water is not always wet 😉

[@haochenvlogs]

interestin

[@Nigan3]

هذا الحجي الزين ،دماغك vip

[@sarah_bahowerth]

The answer is A

[@MedicosisPerfectionalis]

Why?

[@sarah_bahowerth]

@@MedicosisPerfectionalis actually doctor I would change my answer to B, cause I misunderstood the question. What I know is when we affect GFR and become low the creatinine clearance become higher then normal. But what happen in diabetic patient they affect glomerular by VC efferent thus increasing GFR more than normal which ig going to do the opposite and lower the creatinine clearance. What I dont understand is with renal failure that could be caused by prolonged uncontrollable sugar in blood causing hypertension etc. the creatinine would be high. However, I am going with B :,)

[@abody14200]

كل مارحت مكان حصلت الضمير قدامي

[@MA-dd9dd]

My hero

[@MedicosisPerfectionalis]

Thank you 😊

[@Albayuki]

A?

[@MedicosisPerfectionalis]

Why?

[@Albayuki]

@@MedicosisPerfectionalis توكل على الله و خلاص يا باشا

[@sohaibtorab4348]

You surely egyptian man answer by luck

[@hamzataha8718]

Answer is A

[@skyberg1017]

I think when you’re trying to make the video shorter it reduces the quality of the lecture. :/

[@devanshimehta7416]

The answer is d) no change

[@doctorsmile4746]

the answer is B

[@deepalsgian6392]

6:30

[@rehabmohamed7120]

My answer is b

[@shrivardhanborse]

May i know your name doctor?

[@MedicosisPerfectionalis]

Just call me “Medicosis” please 😊

[@haochenvlogs]

@@MedicosisPerfectionalis ok, Don't Tell us your name... but I would really want to take a Fan Selfie with you😊.. I will travel from 🇨🇳 to 🇺🇸🎉

[@tiktokjhakas1708]

Ans:less than normal

[@Travel_t4]

A

[@nourelemam2625]

👏👏

[@MedicosisPerfectionalis]

Thank you 🙏

[@ManpreetSingh-pd9rb]

Wahta

[@viswajakkam9655]

తెలుగులో చెప్పు రా ప్లీజ్

[@khurshidahmed9219]

Hey, Can you please chamge your kiddish way of talking with funny type voices and sometime using foolish words . Also using so much different colors in your slides and so frequently jump from 1 corner to another . To be very honest it does not look nice. Any thing in excess is bad. Be normal. These things make abnormal

[@phython124]

As he mentioned, it is a short review video. Be grateful that the video is available to you for free. Being rude is not "normal".

[@kateskeys]

🌟🌟🌟🌟🩻I would rather have MEDICOSIS diagnose 🩺me than any of my doctors. Just learned my PC had his licensed revoked for God Awful reasons. 👍🏻👍🏼👍🏽👍🏿thank you for these interesting, informative and sometimes hilarious videos.

[@deiaarahman3101]

A