[TALK 12] Structural Biology 2.0: Crystallography - Dom Bellini

Structural Biology 2.0: Crystallography
Speaker: Dom Bellini, MRC Laboratory of Molecular Biology, UK
2024 Introduction to Biophysical Techniques
The LMB X-ray Crystallography Facility offers instruments and expertise to help LMB researchers who succeeded in obtaining crystal hits to collect X-ray diffraction data of good enough quality to solve the structure.
In this video, Dom details the crystallographic project workflow from sample quality, crystallisation, crystal soaking, crystal harvest, to in-house X-ray and synchrotron data collection data, processing and structure validation. He also discusses the impact of prediction programs like AlphaFold and cryo-EM on structural biology and compares the utility of X-ray crystallography with NMR, cryo-EM and AlphaFold for different targets.
The X-ray Crystallography Facility is run by Dom Bellini. Read more about the facility here: www2.mrc-lmb.c...

You can find more videos from the LMB 2024 Biophysics Techniques Lecture series here:
• Biophysical Techniques...
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