C-Reactive Protein (CRP) | Inflammation | Acute phase reactant

[@soufianeelhabachy8171]

CRP is a marker of inflammation c protein is an inhibitor of factor 8 and 5 in the coagulation process c peptide is a chain of amino acides produced in beta cells of the pancreas , it comes from the clivage of proinsulin .

[@MedicosisPerfectionalis]

Excellent

[@timlee8823]

Don't get crp test is you had a vaccine, injury, cold,etc. Wait until you feel OK to get accurate results

[@newdaV1D001]

@@MedicosisPerfectionalis You refer to CRP in your video as an "active" compound of the immune system, hence the "reactive". Therefore and for my understanding, and from what I can read in the literature, CRP is far from a mere "biomarker". It can be used as one, but the classification is wrong by your own statements in the video. TroponinT is a biomarker, as it is part of cardiomyocytes. It is released into the blood stream after heartmuscle damage and can be measured as a sure indicator of myocardial infarction and dying cardiomyocytes. CRP in contrast is a pentraxine, just like antibodies, and has the capability of detecting "foreign to the body", as you said, like bacteria, and non-physiologic, like necrotic cells. Even further it is able to not just recognize necrotic, therefore already dead cells, but also dying cells (that may become necrotic and would be posing a threat to be body in the future by becoming septic), that still have the capability to regenerate. Wherein lies the problem of CRP not being able to differentiate between already dead and gone cells or cellmembraneparts, bacteria and not yet dead cells. COVID-19 was the best example for a viral infection, with a massive uptake of CRP-Synthesis right before patients with pneumonia would ventilators and eventually died later on. The publication here descibes the active role of CRP in the cause of illness and cell damage. I highly recommend it: www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.630430/full

[@benwearne542]

Your sarcasm helps me remember everything

[@MedicosisPerfectionalis]

Awesome 👏

[@holden2966]

C peptide is a component of preinsulin, which binds two alpha chains of insulin molecule. C peptite test is done to differentiate type 1 DM from type 2, because c peptide is available in the body only if there's endogenous insulin secretion

[@DurdyD91]

This is the first vid I am watching from this channel and I am only 7 minutes in and I already love this guy! Funny and educational! Defo subcribing. Thank you!

[@MedicosisPerfectionalis]

Thank you so much 😊 I am honored! Can you please help me by sharing?

[@jayking2762]

Agree 100%. he is humorous and very educational. 2 thumbs up!

[@ibrahimbashimam9149]

this is hilariously educational

[@MedicosisPerfectionalis]

Awesome 👏

[@cabdallahcabdallah4717]

@@MedicosisPerfectionalis is crp 10 normal with thyroid problem? Thanks and Esr 7 mm

[@sanjanathapa8078]

@@MedicosisPerfectionalis जकगजजथकगकगकगंकगंदजथ

[@chuckhoffman8680]

@@MedicosisPerfectionalis😅😅😅😅😅

[@aimz_med]

CRP is an acute phase protein C peptide is part of the proinsulin which is cleaved off before release Protein C is an anticoagulant in blood 😊

[@ShamuAdism]

greetings from Indonesia im a HLAB 27 autoimmune patient, have a high number in my CRP been diagnosed since 2002 , love this channel

[@lilchadzy121]

Currently in the process, still awaiting my hla b27 results but it turns in my fam. My crp was moderately high and my symptoms are looking like ankylosing spondolitis. Hope you're doing well!

[@aprildooley8457]

"I will diagnose you on your crp..said no doctor ever" except my husband's rheumatologist. BTW, he was bit by a tick, his ANA was 1:40, and she prescribed Methotrexate. I said no, no, no prescribe him doxycyline. 3 days on doxycyline and he went from bedridden to ready to go dancing.

[@yasseral-ghabra9518]

C-Reactive Protein is acute phase reactant / Protein-C is innate anticoagulant / C-peptide is a part of preinsulin

[@MedicosisPerfectionalis]

Cool 😎. How would you differentiate between fictitious hypoglycemia and hyperinsulinism?

[@ahmed621989]

@@MedicosisPerfectionalis in hyperinsulinaemia, c-peptide is also elevated, but not in factitious hypoglycaemia

[@MedicosisPerfectionalis]

What if the patient with fictitious hypoglycemia is abusing sulfonylureas instead of insulin. How would you differentiate between fictitious hypoglycemia and hyperinsulinism due to tumor?

[@yasseral-ghabra9518]

@@MedicosisPerfectionalis Levels of C-peptide

[@MedicosisPerfectionalis]

How come?

[@Nat524Ricci]

I love your videos. But also, knowing your love for complex conditions, I would LOVE to know your thoughts on my lab results! I am a very complicated and rare individual, and am finally getting the proper health care that I’ve needed for the past 15 years. Keep doing what you are doing - your passion radiates though your videos and I appreciate the stable and confidence source of knowledge that you share!

[@MedicosisPerfectionalis]

Hey! You can send me an email: [e-mail]

[@Nat524Ricci]

@@MedicosisPerfectionalis awww! Thank you! I will. 💜

[@MedicosisPerfectionalis]

Thank you 🙏

[@dknc7393]

@@MedicosisPerfectionalis I think you said you are "no doctor" and I understand the "liability", but I've been trying to help my mom with her unintended weight loss the past 2 years and then I stumbled across your channel. I have learned and ordered tests outside that her medical doctor would not do or don't have and they could not find out why and reported as idiopathic weight loss. Seeing this other person's request, I wonder if I can also send you some lab results to get to the bottom of the mystery. I greatly thank you in advance. ❤ 🙏

[@MSmusic65]

So good. I love this. Subscribed because you are educational and funny. Those boring teachers at uni just lost their job to you!

[@MedicosisPerfectionalis]

Wow 🤩 Anna, you are the best! Thank you so much 😊

[@SalilTV]

This is edutainment at its best ! Great video - explanation as well as graphics ! Thanks.

[@MedicosisPerfectionalis]

My pleasure 😇

[@yakuphan]

bro i really enjoy a lot of your lectures. both learn the stuff really well and laugh hard at your jokes and imitations. keep up with good work brother, thanks a lot. i mean it.

[@VKell]

Love it :-) I am BSN-RN and currently taking FNP. thanks for the info. you made the lecture fun.

[@dawnmarcelisbendig2667]

I have learned so much from your videos. I am trying to be more active in my health care dealing with my connective tissue disease and your videos have helped me understand my lab results. Thank you.

[@MedicosisPerfectionalis]

My pleasure 😇 Keep fighting the good fight! Good luck 🍀

[@18ignat]

CRP and ESR are not markers of INFECTION BUT OF INFLAMMATION! Just a reminder :) Great video, cheers man!

[@sabasiddiqui429]

But infections cause inflammation, right? In tuberculosis there is inflammation because of infection. So it can be both.

[@user-sq3ls6sj7i]

​@sabasiddiqui429 inflammation is more general, not every inflammation means infection

[@lyzeldyan1507]

information and sarcasms? ICONIC DUO

[@prashantgupta2766]

I need video on antibacterial antibiotics

[@isabellopez6755]

Oh what a great video! I also love Latin! Thank you for the videos !!!

[@Photoguy15]

Listening at 2X speed to you is hilarious ;)

[@MedicosisPerfectionalis]

😂😂😂

[@subashp9663]

Great explanation

[@MedicosisPerfectionalis]

Thank you 🙏

[@gelsayedpt]

To the point man, love how you make it ssssso ssssssimple

[@MedicosisPerfectionalis]

Thank you 😊

[@jayking2762]

Excellent, style, and delivery, bravo!! you are very gifted!

[@MedicosisPerfectionalis]

Thank you 🙏

[@1rrrrrrrrrrr544f]

I love the opening theme

[@MedicosisPerfectionalis]

Thank you!

[@JK20..]

The intro of the video is on point😂😂😁

[@haqzahoorul]

Wonderful teacher. 👏👏👏

[@MedicosisPerfectionalis]

Thank you 🙏

[@mohemmedmohsen3225]

Maaan, I love these videos

[@MedicosisPerfectionalis]

Thank you 🙏

[@faridaakbari7591]

Heeeey! I think, it's first time that i watch your channel it was outstanding and motivational! Loveed! Subscribed🧡

[@MedicosisPerfectionalis]

Thank you 🙏

[@tiazadobbs7475]

Mine was 3.30. Icu for pneumonia and two pulmonary embolism. Thank you Covid.

[@proborini7001]

i'm not a doctor, but i need this video as a medical product application in marketing, so i love you. because the other video is confusing for me, ❤❤❤

[@suzana.h.h]

Amazing 😍

[@MedicosisPerfectionalis]

Thanks!

[@debbiegorsalitz1539]

You are amazing! Thank you.

[@MedicosisPerfectionalis]

My pleasure 😇

[@leonardops09]

Hahaha gracias amigouu gringou, love from Peru! Great videos!!!

[@ahmedtzaki4476]

‏‪3:49‬‏ By the way, I have found some difference between pneumonia and pneumonitis! "Pneumonitis (noo-moe-NIE-tis) is a general term that refers to inflammation of lung tissue. Technically, pneumonia is a type of pneumonitis because the infection causes inflammation. Pneumonitis, however, is usually used by doctors to refer to noninfectious causes of lung inflammation." (- Mayo Clinic)

[@mariocesarbenitez5552]

Thanks so much

[@MedicosisPerfectionalis]

You're welcome!

[@ysllin9635]

well done and so entertaining at the same time ! good partner for quarantine! LOL

[@MedicosisPerfectionalis]

Thank you so much ☺️ Stay safe!

[@zach110]

This guy is HILARIOUS! Haha keep up the great work!

[@MedicosisPerfectionalis]

Thank you 🙏

[@lenaalsaleem3769]

I loved your explanation, keep up the good work!

[@MedicosisPerfectionalis]

Thanks 🙏

[@kaitsaratan]

My PCP seemed to get jealous today that my naturopath ordered c reactive protein. So they ordered ESR. This made me laugh

[@thelostvoicedieverlorenest8487]

You are a genious! and you help me with analyzing the problems Covid creates.

[@MedicosisPerfectionalis]

Thank you!

[@davidcobb7047]

I needed this information. Loved it.

[@daph9843]

i love your hilarious approach HAHAHA thank you!

[@MedicosisPerfectionalis]

You're very welcome 😊

[@simonbreidert5683]

Great! Would love to see more about preventive biomarkers!

[@MedicosisPerfectionalis]

Like what?

[@simonbreidert5683]

@@MedicosisPerfectionalis in-depth mechanisms of all pro-inflammatory markers and maybe how anti-inflammtory cytokines counteract.

[@DoniyorToraqulov-pl6pk]

Great i love your channel

[@منىعبدالخالق-م2ذ]

Thaaaaanks for your usual amazing explanation 🌸🌸🌸🌸

[@MedicosisPerfectionalis]

My pleasure 😇

[@dimaria8029]

So much thanks🙏🏼😊

[@MedicosisPerfectionalis]

My pleasure 😇

[@MA-dd9dd]

Very informative

[@MedicosisPerfectionalis]

Thank you 🙏

[@nasrinrastegar980]

Man you are fantastic!

[@abc_cba]

9:25 that was the girliest voice I've heard ! Funny :) thanks for the videos.

[@DrReginaldFinleySr]

Great video. Thank you for sharing!

[@MedicosisPerfectionalis]

My pleasure 😇

[@rachelx1379]

Thank you for the video very informative as I had no idea what it all meant! I’ve just had a blood test & my CRP is 5.57. No fever or pain etc. Heart disease and strokes in my family so have made an app with my gp.

[@MedicosisPerfectionalis]

Making an appointment is the right decision...Don’t think about lab result without thinking about the whole picture.

[@sphesihleidentical2334]

your jokes makes me enjoy and understand your lecturer " shup-up"

[@MedicosisPerfectionalis]

Wow 🤩 Thank you 😊

[@manarsmaan2624]

losing your mind right now is better than losing 🤣 in the test . I agree

[@MedicosisPerfectionalis]

😊😊

[@drmukeshpatel1348]

Best video nice teaching way ever..really appreciate

[@MedicosisPerfectionalis]

Thanks, dear :)

[@NiRioMas3]

“I hate myself” 🤣. Nice video. In Latinamérica we say “traUma” 🤓

[@krystalceballos6916]

love this😂 !! thank you.

[@MedicosisPerfectionalis]

My pleasure 😇

[@susannahwhite7561]

Excellent!

[@shahabuddin6149]

Great lecture thanks alote sir

[@MedicosisPerfectionalis]

My pleasure 😇

[@kcc531]

I enjoyed watching this so much. You're hilarious mate.

[@MedicosisPerfectionalis]

Thank you 🙏

[@alaamincr]

thank you so much , it's amazing, very helpful in learning and refreshing medical memory , it's great way to get both basic and advanced med knowledge , the best way to be addicted with CME . excuse me I've a question : CRP : its role in the evaluation and monitoring disease activity , or flaring of SLE ? because we have been learned that high CRP in SLE (only SLE ) means there's a possible comorbidity or infection and we should rule out it ?!, or the negative CRP in SLE means nothing ? may you give me your explanation and opinion ? thanks

[@alaamincr]

the age of patient divided by 2 plus 5 =the normal range of ESR , so do you agree with me or it's not accurately method ?

[@joshuamaluegha2946]

this helps my thesis for graduation hahaha

[@MedicosisPerfectionalis]

Good luck 🍀👍

[@elianastone7124]

"Go to hell bacteria!" Love this video, educational and engaging! Keep up the good work!!

[@radouanek7708]

Does CRP also rise in response of viral infections/ viral induced inflammation ?

[@partomeraji3084]

U R amazing. I'm not kidding.

[@MedicosisPerfectionalis]

Thank you 😊

[@jimenabenitez8181]

You're amazing.

[@MedicosisPerfectionalis]

Thank you 😊

[@deepashriramesh51]

Hello sir,lots of love from India,your videos are absolutely amazing. Just one doubt, crp Half life is 18h right?

[@intuitknit]

Could the obstetric complication be preeclampsia? In that case their is supposedly inflmmation in the placental attachment blood vessels.

[@victoriamattiello7090]

I love your intro and your videos, thank you!

[@MedicosisPerfectionalis]

My pleasure 😇 Thank you so much for watching!

[@chrismallory1167]

I met active lipid at Purdue. She was 235 lbs

[@fatawa242]

Great 👌

[@eliascorrea8573]

Great also for immunology! go watch the video and stop reading comments.

[@MedicosisPerfectionalis]

Haha 😂

[@shrisharma7355]

That's super informative and you're really witty. :D I was wondering, what does it signify when esr levels don't fall down post covid recovery? I've been tested positive twice since last year. And ever since that, esr and CRP levels never returned to normal range. I'm not facing any physical discomfort whatsoever. Yet the readings. Should I be worried?

[@CaptainVelveeta]

I'm no doctor but no, you shouldn't be worried. There are all kinds of labs that may read high but are not treated because the patient is asymptomatic. Throw in the fact that we know nothing about how Covid-19 works, lives and plays, as long as you're not symptomatic then there's no need to worry. I would, however, advise increasing activity to strengthen the lungs. That's always a good idea regardless of the condition.

[@shayaan7860]

You are a great lad!

[@MedicosisPerfectionalis]

Thanks

[@dr.labanizaman55]

You said half life of CRP is 7 hours but in Davidson it is 18 hours. Could you pls clear the confusion??

[@waadalramoni5690]

OMG i love you man😂❤️❤️❤️❤️❤️

[@MedicosisPerfectionalis]

:)

[@umamaheswari6699]

Nice sir.. Moreover we are looking forward to some of the microbiology topicss

[@itsqueenbeautiess9552]

My CRP Value is : 1.70 mg/dL My labs Standard Range

[@TheseAreShapes]

Just got tested at 65.7 mg/L - yes I wrote that right! 😱 hopefully my doctor will explain it to me

[@MedicosisPerfectionalis]

Best of luck! Don’t jump to conclusions based on one lab test! Talk to your doctor!

[@piaakasyapa]

What was the result and treatment you hve taken...tell me

[@TheseAreShapes]

@@piaakasyapa ulcerative colitis- prednisone 40mg daily

[@TheseAreShapes]

@@MedicosisPerfectionalis yes, if you're curious the result was ulcerative colitis

[@paulg9229]

@@TheseAreShapes for how long do you need to take?

[@lajwantishahani1225]

Love your video and subscribing to learn more from you. My CRP report today had the value at 7.35 which I get is high but not too high, but while the report doesn't seem to cover ESR other parameters like creatinine and uric acid are high, and for the first time cholesterol is all over the place. Previous tests have reported some injury to the kidneys. Could you please explain that to me? Btw, I recovered from Stage Zero bladder tumor almost five years ago. Will be doing my pelvic ultrasound within a week so hopefully that can throw some more light so that I can get a better handle at how to clear this new inflammation. Or did it ever go away?

[@GoodFilmStudio]

1:21 Ain't things other than proteins like katecholamines, androgens, T3, or Platelet ACTIVating Factor also active?

[@rawanalzehair4714]

Hello sir , thank u so much, I have question, Is CRP increase in both viral and bacterial?

[@musangilaiebalanga6040]

The 3 are different and are not correlated. C peptide is the remaining product after insuline is realised from the storage center in pancreas. It insulin is linked with c peptide while on storage in the pancreas. Protein c is bleeding factor

[@anaraquelmendoza4087]

Hello friend, firs of all great video. I would like to know if C- Reactive Protein, Quant is the same?

[@sujatasood9991]

Thanks for v .good video I am 32 plus and diagnosed with ibs along with celiac since one year now in the month of this March my crp was 14.80mg/L and lymphocytes 3.50 (X10A3/uL) plz do reply is it dangerous sign as i feel continuous cramp inspite of all precautions of eating but doctor did not told me any thing ?

[@dragnsmeldy3566]

I am a minor, still in high school, so if I sound like an idiot, please forgive me. For around a month now I have been having intense pain around the nerve root near t6 or something like that, and the pain has been moving. I have been In a lot of pain as I breathe, sometimes the spots it hurts to breathe change. In the last week, I have been experiencing unexplained nausea and vomiting, which has been a nightmare. In a very recent blood test, it was shown that I have inflammation and/or high crp ( I don't believe they told us the exact number though) and my doctor has ordered an MRI with contrast. We still haven't been called back for the appointment to be made, but it has been approved by the insurance company. I am honestly a bit overweight, and I do have hypothyroidism, which is being treated, but everyone is telling me it is not my fault. I'm scared in all honesty. Do you have any advice for me and what I can do to help the stress of it all?

[@MedicosisPerfectionalis]

I think you should listen to your doctor; Do the MRI and wait for the results.

[@dragnsmeldy3566]

👍

[@oneseeker2]

Viral Pericarditis? Pleural Decisions in lungs? Dr could have seen this in X-Ray!

[@Chowanana]

How does it cause the classical pathway of the complement to activate?

[@cherrrriii]

why did u mention "Quelling reaction"? couldnt link it to the definition 😭😭

[@HadleyandRachelrun]

What if you always have a high CRP? My CRP is check about every three months and is always high. When does the acute inflammatory marker become a chronic inflammatory marker?

[@trustinalqadir2982]

Nice vedios. And method was great. Today my Mother's ESR IS 25mm/1hr. And Eosinophils 08% I am confused to which Dr we should consult.She is sleeping to much.drowsiness feeling is also please suggest me

[@arifmarwat5973]

Please correct cystic fibrosis is autosomal recessive not Dominent

[@davidcunningham2984]

very funny. would love to see you cover more general health topics such as heart disease diabetes covid 19 etc.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@Scrubsandscreens]

Difference between crp and crp quantitative

[@gregd4391]

What is ESR is normal, but CRP is 13. Is a higher CRP expected for a high-level, competitive power lifter?

[@fahmeedatasnim2175]

Thanks 😂

[@MedicosisPerfectionalis]

My pleasure 😇

[@fatemaabbas1861]

Hi interesting video thankyou for educating us. Just a question im a female 30. My ESR was just by 2 points high at 22 but was recovering from a cold. But CRP was normal 2.2 Does that mean anything?

[@mjrosales5986]

Is this dangerous? I have 30.18 crp

[@sillypantses]

Would using DHEA lotion put people at similar risk to the contraceptive pills?

[@ghizlanet8276]

first thank you for your video !! but i got a question. Are cancers always accompanied by an increase of CRP? because cancer progress is generally silent, the cardinal signs of inflammation are not always there.

[@MedicosisPerfectionalis]

Good question! Not always

[@b.i.k.i.b.i.k.i]

@@MedicosisPerfectionalis Gotta say I loved your video! I chuckled… I never chuckle whilst watching medical videos 😄 If I may ask, can a person with a CRP result of 1 have cancer? TIA You have a new subscriber 👍🏻

[@rozacielo7792]

love your informative videos ... but please do slow down , its not easy understanding you when you speak so fast. Thank you

[@MedicosisPerfectionalis]

Thanks-dear-for your feedback

[@runalong]

You can click the little gear/cog setting button on KZbin, and adjust the playback speed to .75 or .5 x and that will slow things down 25% or 50%.

[@manjup1807]

CRP test is Negative. What it is showing? Please explain