The Cholinergic Receptors

[@mayam6680]

Every time he says "ISN'T THAT COOL" I find myself grinning while nodding enthusiastically like what the hell! This is SO cool! I can't believe how much I used to hate that shit when they actually make a lot of sense! Just THANK YOU! You're my hero ❤

[@sharonife9994]

I know right. ...so damn cool

[@bjarnij3782]

Your videos on receptors has been HUGE for me! Thanks so much.

[@jaimiedraper]

This is the first video on these receptors that actually helped me. Thank you so much!

[@chariscourtney2577]

This is the best summary video I have found so far for cholinergic receptors. THANK YOU!

[@biggiggles08]

This is really helpful. I was quite confused when I first learned this in class, now I'm studying for step 1 and the language had be SUPER confused. For instance, people using the words anticholinergic and antimuscarinic interchangeably with parasympathetic inhibition - when in fact they aren't the same. This video really helped me to understand what the differences are between those - it all has to do with the different sub-types of receptors.

[@MedImmersion]

I'm glad I could help Lomo!

[@placebiak]

you are like... THE HERO !

[@nomsyemmanuel2717]

F

[@danishlone3441]

Indeed

[@regankhadka4631]

One of the best channels for medicine.

[@ShawnKim314]

I almost cried... so... perfect. Thank you very much for making this lecture.

[@MedImmersion]

Awww - I almost cried at your nice comment... I'm a resident right now guys so I'm sorry that I don't have time to work on medimmersion. Hang in there, school is over before you know it!!

[@rpgdream9700]

u sir are FRIKKING BRILLIANT!!! dude that was 1000% times better than my boring as hell lecturer DUDE, all my love

[@MuthoniMinaKimani]

Thank you so much for this! Thank you!! You've really helped me, I have been struggling with these concepts for s long and now that I finally get it I feel a lot more confident about my finals, thank you so much

[@nethus1635]

Thanku very much! I have been searching for this kind of video for a quite long time. Annnd I finally found it thanks to you sir! I wish you stay healthy and make this kind of videos in future too.

[@scottgenereau1512]

Yeah, this lecture was the shit. I am studying pharma right now for my NCLEX exam I am taking soon, and I am too lazy to just memorize without understanding therapeutic/side effects of medications without at least trying to understand WHY they exist. Videos like this really hammer home concepts that allow me to understand and not just memorize side effects, etc. I feel like much of the nursing text spits out terms that we just don't have enough time to delve into further. I have a problem with that. (I have OCD) I loved the diagrams for the PNS and SNS systems and the nerve innervations. Explanations were super clear. Even as a nursing student, I did pick up on the 'Chromotropic' error, haha. I am just not content to know the basics, I need more because it scares the shit out of me in a good way that my knowledge of this stuff is gonna help me to better communicate to providers to increase patient safety. Thanks.

[@MedImmersion]

+Scott Genereau - Good luck dude!

[@masihmasihmasih]

hahaha lolz i thought you wrote "Yeah, this lecture was shit" i was like da hell this is good hahah

[@valentinanikolic1272]

Scott Genereau

[@dollarking9641]

Ur comment is too long

[@nrcg2317]

Goodman & Gilman's the pharmacological basis of therapeutics has an excellent description of the autonomic nervous system and how drugs function on it. You won't have to memorize. This cannot be memorized. You have to understand the logic.

[@marwamokhtar8469]

This is the most informative and interesting pharmacology lecture I have ever heard! Thanks alot!

[@71jimee]

You do a great job putting things together and making it make more sense! Thank you for your time building these videos!

[@MedImmersion]

You are very welcome!

[@shahinshahsavari1275]

Nailed it! Shoulda watched this the first time I learned all these. I think I won't forget.

[@johnh6093]

OMG! this lecture saved my life!!!!!!

[@michaelleonardo8193]

You're videos are AWESOME! I'm really learning a lot!

[@sahel600]

Sir, you're a life saver and a great instructor

[@ravigwankhede]

Excellent explanation and elaboration. You made it so interesting. Thanks

[@jeniferzabala7538]

Thank you so much! I feel that seeing your videos is a good invest of time.

[@Lizzy900-p3h]

I wish I found you earlier! You are the best! Thank you so much!

[@huwguyver4208]

Great work mate, this is way more helpful than my lazy Pharmacology lecturers.

[@MedImmersion]

Good! I'm glad you like it. Stay tuned for more mate! : )

[@forehead411]

i mean...dude YOU ARE AMAZING!!

[@Duckguts1]

Best lecture ever...made things so easy👍👍

[@Marc-hs5ye]

This is the best video ever. Thanks

[@virgilnanaquewitung2272]

Awesome video man, you sure clarified so much clutter!

[@muhammadhuzaifa8649]

awesome man . very detailed and easy explaination .

[@lucilaalvarez4095]

Best video on this topic and ive watched all of them! Thank u! 🙏🙏🙏

[@hamnakhan4483]

these lectures are just awesome but i need others too e.g., indirect adrenergic agonists or adrenergic antagonists etc

[@oanhpham1137]

thank you!! it provides simpler and more perspicuous explanation than my books

[@MedImmersion]

oanh phạm You're welcome Oanh!!

[@shimadavari4501]

thank u so much for all useful videos .do you have any videos for cholinergic antagonist or agonist?please

[@habibibrahim4748]

the fantastic vedeao i got today, easy perfect ,i hope more and more or all pharmacology

[@karaprzybyla]

Fantastic! Any chance there are printable notes to accompany this lecture?

[@bowenlim1691]

You are the best, true life saver...

[@ravykiran8928]

just awesome......!!!!!!!how can u be so cool while explaining lecture....

[@MedImmersion]

It's easy. I wear sun glasses, a bath robe, and Nike sandals over my socks while listening to vanilla ice, and bobbing a pipe from my mouth. After that, the "cool" just flows like a harpoon daily and nightly

[@ravykiran8928]

as expected.....lol

[@miralepaulsen9891]

You are a fantastic teacher!!!!!!

[@MedImmersion]

Mira le Paulsen Thanks Mira! Good luck in school.

[@hollyozioma]

You are an amazing teacher. Thank you!

[@randayousif8887]

OMG!! this is awesome 😍 thank you

[@davidvarela6020]

excellent in every respect! thanks so much

[@videosofmikey]

This is fantastic well done!

[@rahulbasu9779]

Great videos ! I have a much clearer understanding of the receptor functions now thank you. Could you possibly make videos regarding Gi and Gq proteins please?

[@jaquelinemanuel5716]

You're a great teacher! Thanks!

[@MedImmersion]

+jaqueline Manuel - No, you're a great student!

[@MedImmersion]

+jaqueline Manuel - No, you're a great student!

[@mohammadkamal6073]

You must replace our professor!! Great work!!

[@moustafahassan7386]

just superb !

[@mohammadteimoori6614]

so nice …. so cool ...good luck

[@sarahparker9583]

Great lecture, thanks for your help!

[@pratibhagupta8816]

I see your video first time and it's really cool😅😎😎,

[@podcastersedge6757]

can you please make a lecture on multiplicity of action of Ach...?? it will be a great favour

[@kcaiquee]

You made it simple and helped me a lot!! thanks

[@ThaoLe-tn7cq]

Great job! It's really easy to understand and memorise. Thanks a lot

[@doczak69]

Great work ...thanks for the pain taken to explain it so well

[@MedImmersion]

Thanks doc!

[@luketwaits5998]

Dude, you rock my world! Thanks so much!

[@MedImmersion]

+Luke Twaits Your welcome!

[@goodmorningsomalian5514]

Doc if you can send us the link for your slides that will also help thanks

[@pierrejade]

very pedagogic explanation!!!

[@princessvega13]

Amazing video, great job at simplifying some tough concepts.

[@calendar53]

Thanks a lot. Where can i get a link for the image of receptor's chart? Thanks

[@KKurtz215]

What is the link to the diagram? I don't see any description posted. Thanks! Great Video!

[@monikarao882]

Awesome video. Thank you very much...!!!

[@Shubham-pt8rv]

Brother can you plz give the link to download that images of shit of sympathetic and parasympathetic, which you explain

[@amhareiner]

This Veterinary student thanks you!!!

[@MedImmersion]

You're welcome Jacqueline! Good luck in school!

[@mariadurek298]

really really good lecture! thank you!

[@AsoourE]

Again, really helpful!

[@tanunit]

This is really helpfull thank you so much sir

[@faypapa3794]

keep up that good work! Thanks so much

[@sonalparmar1870]

Does muscarinic receptors are also found pre synaptically

[@ashishbhensdadiya3078]

Pls upload video of cholinergic agonist and antagonist

[@biswajitnath804]

Great one bro...

[@cinderellaalmatrooshi797]

Thank you so much! I finally understand!

[@sausagebobgrett3401]

damn, you are better than any teacher i ever had..

[@skarpengland]

Is it safe to assume, that since ALL preganglionic neurons are cholinergic, ALL postganglionic neurons have nicotinic receptors on them?

[@rokayaoubi845]

it's great thank you and please complete the rest of mentioned drugs

[@MedImmersion]

+Rokaya Oubi - Definitely! I'm working as fast as I can! Good luck in school!

[@merrymeridian9372]

How nicotinic receptors facilitates the rest and digest?

[@johncadillac2005]

Excellent Presentation

[@Theotherguy256]

thanks doc,you have helped me on this,thanks allot.

[@gloriousgod]

Really good video man!

[@nellyhoffman6194]

Thanks Doctor ! :) You are the best :)

[@chmith27]

chronotropy, not chromotropy. great lecture.

[@MedImmersion]

Yeah, I need to fix that! Thanks!

[@zachfertas8690]

quand le sage montre la lune , l'imbécile regarde le doigt.

[@nellyhoffman6194]

You are 100 % true bro

[@nellyhoffman6194]

Stupid shit THis was a great lecture

[@chmith27]

which is why i too said, "great lecture". but what the heck is wrong with helping correct a tiny error but one that could be confusing (there's chronotropy, dromotropy, and then chromotropy gets thrown in there now)? this was not a criticism, and not stupid shit. it was minor shit. very minor. but that is a common thread with commenters on the internet- they take things too personally. this guy does a great lecture, and i think i watched severall other flawless lectures. now he can make this one flawless. wtf is wrong with that? maybe you took offense because you have thin skin or something?? she or he took it appropriately as it was intended- to be HELPFUL.

[@ginggyuniverse8371]

Thanks Joe.... U realy awsm... Pls upload more and more....

[@anomalyp8584]

Thanks for the explanation! I've noticed you said 'chromotropy'. Please note that it is 'chroNotropy'...it's about the tempo. Thanks again!

[@MedImmersion]

Haha! You're right! Thanks so much!

[@user-ul9pv8fu2i]

Thank you this is soo helpful 👌🏻❤️

[@maheshtanay]

After taking brahmi, shankapushpi for one month my memory is weak and cant able to sleep deeply. Need help.

[@emiliciousize]

omg!! You should be my Pharm professor.

[@mahrukhzaidi2440]

Superb❤

[@jpeachessss]

Dude you’re awesome!

[@ArwaAbu]

Thank you so much for this!

[@louis424]

hi joel, so nicotinic receptors find themselves presynaptically for both adrenergic (SNS) and muscarinic (PNS) neurons. Why does nicotine (as far as i know) have a generally stimulating effect then? i understand it's because they trigger the adrenergic neurons, but do they not also trigger the muscarinic neurons?

[@miraikaisar386]

+lou ovcm Well nicotinic receptors are only excitatory (muscarinic can be either excitatory or inhibitory) this is why they have a stimulating effect. And well, nicotine ONLY stimulates nicotinic receptors not the muscarinic ones. Now yes, ACh stimulates both; however, you're asking about nicotine only. In this case it wouldn't affect the muscarinic.

[@louis424]

hi, thank you for your answer. from what i understand, nicotinic receptors are found upstream of both the sympathetic (adrenergic) and parasympathetic (muscarinic) systems. What I'm understanding, but may be wrong, is that both these systems require presynaptic nicotinic activation. so i understand that nicotine, binding to the nAChR upstream of the adrenergics will activate the sympathetic system, but I don't understand why the nicotine binding to the nAChR upstream of the muscarinics would also activate the parasympathetic.

[@jerejh3]

+lou ovcm hi i'm a just year 1 medical student so correct me if i'm wrong :) everything u said was correct and nicotine actually does stimulate both the SNS and PSNS. This is why smokers sometimes feel more active but in other times very relaxed depending on the extent of which nervous system was stimulated more. Did a little research and I think this is known as Nesbitt's paradox

[@MedImmersion]

+Jeremy Chan - Cool! I didn't know that! You da man!

[@louis424]

you're a champ, thank you

[@lizardoblivion]

Thank you for the clarity! Very helpful, indeed:)

[@MedImmersion]

Good, I'm happy to help!

[@doctorsara8247]

Perfect lecture !! Thanks alot :)

[@educationalservices2518]

great lecture

[@emansaber1358]

you are amazing.. thank you so much

[@mashthekashmj4337]

anybody got the link to the diagram he showed??

[@ItendshereXiii]

this is more than awesome many thanks :))

[@DudeWhoSaysDeez]

So what does smoking do? You get nicotine. So does that attach to your parasympathetic nerves?

[@goodmorningsomalian5514]

Thanks man you helped a lot

[@deekshithadanthuluri9247]

loved it !!!

[@olanahgray658]

Hey I'm having trouble finding the link for the print outs. Can you tell me where they would be?

[@MedImmersion]

I'll put them in the description as soon as I get a chance. Thanks!

[@olanahgray658]

Thank you very much!!! Also, your videos are very helpful. Im a first year pharmacy student and I was completely lost when it came to the topics of the receptors so thank you very much for taking your time out to do this.

[@ned9819]

Sir I Salute you.Thank you.

[@MedImmersion]

Haha! Roger that dude! Thanks!

[@baraakareem4783]

really great and helpful thanx

[@MedImmersion]

You're welcome!

[@shehzadimubarika4769]

Thank you so much. great Lecture

[@MedImmersion]

Glad I could help Shehzadi!

[@shehzadimubarika4769]

+Med Immersion Thank you once again!

[@siddhantjain7353]

Shehzadi Mubarika

[@anumumair6669]

y u said heart has nicotinic Receptors please explain !!