Melanocytic Dermpath Basics: Immunohistochemistry

[@JMGardnerMD]

A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

[@tamilarasirenganathan8243]

Thank you so much. I have learned so much from watching all these lectures. Great help. Really appreciate. Now I am more confident when I am looking at melanocytic lesion.

[@Nicollas16]

Which IHC stains I like for different scenarios: 2:06 S100: 9:30 Melan-A (MART-1): 11:45 HMB-45: 13:17 SOX-10: 16:11 Lentigo simplex: 18:20 Lentiginous nevus: 27:17 Dysplastic (Clark's) nevus: 30:39 Melanoma (lentigo maligna type): 50:14 Melanoma in situ vs melanocytic hyperplasia in sun damaged skin: 58:11 Melanoma in the dermis (metastatic pattern): 1:11:04

[@JMGardnerMD]

Thank you!!!!

[@pathologygeek7360]

You can get a great Dermatopathology review course of 15 lectures from the Oakstone institute or payloads store: m.kzbin.info/www/bejne/gJ6xnJiohJh3ibM store.payloadz.com/details/2573416-movies-and-videos-educational-dermatopathology-oakstone.html

[@JMGardnerMD]

Also check out my videos on melanocytic nevus basics (kzbin.info/www/bejne/oHy9daSAmt9soNk ) and melanoma basics ( kzbin.info/www/bejne/bn-Teo2QpatrqtU ). And be sure to read the disclaimer in the video description above.

[@Woffle8340]

7 Foot rats, rats along his rats. when he calls your rats, it all fades to rats!

[@pavelboico9283]

Today our pathologists recommended PRAME to differentiate melanoma. Is it useful marker?

[@JMGardnerMD]

Yes I like it a lot. It’s not perfect but can be very helpful in select cases. I had no experience with it at the time I made this video which is why I didn’t include it.

[@janiranavarro]

Thanks Dr Gardner for this video!! Super helpful and educational!!

[@sevtaptolaman4812]

Thanks very much!These videos make me change my perspective

[@franciscosimental4930]

Dr jerad: why does "melanoma in situ" not appear in the histological classification of melanoma? It seems to me that it is a term that is not widely accepted because it does not meet defined criteria, does it?

[@JMGardnerMD]

It’s not a histologic subtype. It’s more like a stage. It just means melanoma that is confined to the epidermis and hasn’t invaded.

[@franciscosimental4930]

@@JMGardnerMD thank you

[@gabrielaacuna4036]

Great!!! Can't wait to watch it! Love your videos! Thank you so much :)

[@zhengxiaomin3638]

Great! It is exactly what I am looking for. Thank you, Dr. Gardner

[@johnfazio2892]

Great review of melanoma IHC. Very helpful.

[@arkarhtoo7797]

Thank you. It’s a very nice lecture. I learn a lot from your videos. I have a question. In case of margin assessment for melanoma in situ, can PRAME be a better way of assessing than other markers?

[@JMGardnerMD]

I haven’t tried that but I think it would be difficult to use in that way. I see PRAME stain background melanocytes sometimes especially in sun damaged skin so that would Make it hard to use for margins I think.

[@goharrehman7710]

the green stain is from grssing

[@evelyne7071]

You’re a really great teacher !

[@paulo4856]

Thanks, Jerad.

[@luisfernandocardenascardon8100]

Great video!!!

[@harimartinez1039]

Thank you ☺

[@AhmedGamalPost]

Thank you

[@jennah19]

Thank you!!!

[@MauriceMQLD]

I honestly can't thank you enough for what I've learned from your videos. You have demystified many concepts in dermpath for me. Greatly appreciated.

[@JMGardnerMD]

Thank you! Such a nice compliment.