Microbiology - Helicobacter Pylori (Ulcer)

H. Pylori common cause of ulcers
/ armandohasudungan
Support me:
/ armando
Instagram:
/ armandohasudungan
Twitter:
/ armando71021105

[@emmanuelndaba8296]

Now watching this videos makes me emotional 😭 Today I’m watching as a medical doctor, started watching his videos about 10 years ago in premed degree (BSc) and medicine. You are amazing and loved. Lots of love from South Africa 🇿🇦

[@boopbeeppp]

Inspiring! Kudos to you, Doc!

[@TheCrabbyLeo]

If 50% of people naturally have H. pylori in their gut, how does the urea breath test differentiate the results of an actual infection vs natural occupying bacteria? Is there a certain threshold of tagged CO2 being exhaled to be considered "positive"? I assume the natural H. pylori produce their waste products regardless of infection status

[@tawfiquesoboyejo2353]

This is literately the best thing I've come across in a while

[@medicstudentscucms3142]

em. I think there is a correction here. the mucus is produced by the epithelial cells itself. There are no goblet cells in stomach lining

[@armandohasudungan]

you are right that is a mistake on my part. cheers!

[@rbhattacharya3631]

FOVEOLAR CELLS

[@letsomethingshine]

Both goblet cells and foveolar cells are epithelial cells. Most mucus in the stomach is produced by foveolar cells. In the lacrimal glands, mucus is synthesized by acinar cells instead. But goblet cells are found in abundance in the respiratory tract, intestines, and eyelid conjunctiva. ~ "goblet cell" at Dorland's Medical Dictionary ~ Guzman-Aranguez, A; Argüeso, P (2010). "Structure and biological roles of mucin-type O-glycans at the ocular surface". The Ocular Surface. 8 (1): 8-17. doi:10.1016/S1542-0124(12)70213-6. PMC 2847370. PMID 20105403. ~ Histology image:11303loa from Vaughan, Deborah (2002). A Learning System in Histology: CD-ROM and Guide. Oxford University Press. ISBN 978-0195151732. - Digestive System: Alimentary Canal: fundic stomach, gastric glands, lumen"

[@lucutes2936]

Oof

[@jolinejoline2471]

@@armandohasudungan HP infection ->acute gastritis which can go in 3 directions, one of which is atrofic gastritis of the body (it can manifest in gastric ulcers or metaplasia). If it develops into Metaplasia then some of the stomach cells get replace by Goblet cells.) proceeding towards -> Displasia ->Adenocarcinoma .

[@epicsuper6775]

I am doing the Helicobacter Pylori treatment now, and now I know why I am taking the proton pump inhibitor pantoprazole. Thank you very much for this very good explanation.

[@xian.1352]

How is it going with you? Bdw ppi will lower hcl, ph will be more alcaline, digestion of food will be harder. Malnutrition will be worse. Also pylori will have an easier environment to live in no? Why do doctors prescribe ppi then?

[@xian.1352]

I also heard that h pylori makes you produce less HCI, so that’s why ppl get acid reflux, bcs low HCI makes the esophagus to remain open. I heard that.

[@xian.1352]

It’s quite hard to understand. People have different opinions, it makes it hard for you to know what exactly is going on, and what to do...

[@epicsuper6775]

@@xian.1352 I googled these info out and hope they are helpful. The pylori triple therapy (clarithromycin, amoxicillin and pantoprazole) first kills off pylori bacteria in 7 days or 14 days. However, the lesion of stomach ulcer is still there even after this triple therapy. In order to heal the lesion, you continue to take the PPI pantoprazole because without PPI the stomach ulcer will agitate normal cells to produce excessive stomach acid and hence to worsen the lesion. For me, after finishing the 7-day triple therapy, the doctor asked me to continue to take PPI pantoprazole for 6 months, then I will be back to the hospital to check the presence of pylori. I have finished the 1st month of PPI. I think it works because my stomach ache is now much milder than before.

[@PankajRajput-cv5rw]

​@@epicsuper6775how are you now❤

[@ramraja7796]

I am not in a Medical profession but your explanation was almost understood and has given me insight on what is H.pylori, Well done, this is the best Video for non-medical minded persons like myself, Thank you Armando.

[@davidpotter3777]

Thank you, just got out of the hospital. Your illustrations and explaining of this bad bacteria is very good, you are an artist also.God bless you and your family Aloha

[@solidname9085]

Did you recover from h pylori?

[@momaldonado3248]

@@solidname9085I just got diagnosed with it. I got a 14 day med plan for me. I’m half way thru and alrdy feel better.

[@ayeshagotgifts7753]

@@solidname9085 did you recover

[@raphaelmalpica401]

Not even the First Aid for USMLE explains this how you do, phenomenal video!!! This made things so much clearer!!! Gracias!!!

[@sanjeevshrestha2441]

Can you pplease tell me the name of medication

[@sanjeevshrestha2441]

Can you please tell the name of medicine?? Reply me

[@aryanpandey2576]

Sanjeev Shrestha amoxicillin and omeprazol

[@sitihajar6488]

finally get the picture on how h. pylori cause ulceration. really helps. thanks!

[@nadaglgl5651]

Seriously your way of explaining is on another level ❤

[@DEMCarnage]

Thank you so much for that explanation... my mom was just diagnosed with H pylori and stomach cancer. This video really help me understand her condition

[@223froggyfun]

How is your mom doing now ?

[@amahlemasondo7857]

Bro how is your mother?

[@pavanpabbireddypavanpabbir1897]

hi bro how is she now?

[@ShazmanDaShiznit]

All your videos are great and really help me get through my PBLs (problem based learning) in medschool. The anatomy and physiology is explained better than how my lecturers teach it and simplified which is convenient. You are extremely talented and I really admire your work. When will the website be finished, do you have any idea? Because your artworks and mind maps are very good and visual photography like this tends to stick into my head quite well! Well done, have a great continuation

[@mariyahahmad5387]

Same reason that makes me watching this video.

[@macdoniaski7955]

I don't comment on videos but since I watched few videos of yours,is like taking you to be my personal teacher.......homie you really break things down,once small thanks for the video👌👍

[@user-tu3sx4rd7r]

Excellent and wonderful content. We thank you and I would like to add that there are natural things that are excellent and very effective in eliminating them, such as licorice, cauliflower, cabbage and turmeric, as well as garlic immersed in olive oil, which give great results.

[@user-Red5hield-exp0ser]

You have to think of H Pylori for what it is. It's an overgrowth of a bacteria that we already have to try and combat whatever problem is happening within our bodies. Not being angry with it is the hardest thing to start with, but it's the key beginning steps to overcoming this life changing bacteria. I had to go onto quadruple therapy, which was *TETRACYCLINE, METRONIDAZOLE, PEPTO BISMOL, and OMEPRAZOLE* Triple therapy failed twice for me. You have to lower the amount of HP bacteria to healthy levels. I lost 40 lbs in weight due to this bacteria, but I prayed every day, I tried to think of it as my body was trying to overcome whatever was happening by increasing the HP to compensate, and I took the harsh antibiotics which temporarily raised my liver ALT levels. You can do it the natural route but it is very expensive!! Key things to remember: 1. Think positively (you will beat it) 2. Pray to our creator and saviour. 3. Avoid sugar, gluten, and dairy until it's gone. 4. Take the quadruple therapy or all of the required expensive supplements. 5. Refer back to number *1* Good luck, and God bless 🙏🏻

[@MrWallpie]

Long term use of PPI in H. Pylori infection is associated with atrophic gastritis which is one of the primary risk factor for gastric cancer. Otherwise great video thank you.

[@WishesRT]

YOU ARE THE BEST TEACHER SRSLY

[@smartDoctorsclub]

💯

[@leenahmed147]

Amazing explanation, you put everything so well and made it so simple to understand. Greatly appreciate it, Thank you so much !

[@StevePhillips]

This is excellent and so much fun learning; The substance sulforaphane, which occurs in broccoli and cauliflower, has been proposed as a treatment. Though most doctors I understand will prescribe antibiotics as you mentioned along with 2 other medications.

[@thewingmakers161]

Interesting because both of those are man made vegetables

[@StevePhillips]

@@thewingmakers161 I never knew that. I thought they were natural.

[@Cleopatra-en4ye]

Perfect explanation! Thank you!

[@Ryan-jv9se]

This guy explained h pylori so well.. explains some seemingly contradictory things about the bacteria.. very well done

[@ananyasampath827]

Thank you! This helped me understand what my tummy is going through!

[@CarienvdW]

This was very helpfull as all the articles make this so complicated, but with the drawings it suddenly becomes very clear. Great video!

[@henryphilippeaux3566]

It's criminal that this video doesn't have more views.

[@elizagal7451]

Got me through the place I didn’t understand which was how/where all that extra stomache acid comes from with an ulcer. Thank you

[@joannabarcikowska6409]

Antibiotics are safe? As I need to decide how to heal it

[@EACHONETEACHONE09]

But why would you want to add in a PPI to reduce discretion of HCL when it’s HCL acid that keeps H. Pylori at bay. The bacteria can only grow in an Alkaline environment.

[@renupathak4442]

Excellent delivery, facts, diagrams and so too the point. Great

[@zeenadthomas6818]

Exquisite drawings! Wonderful explanations!

[@user-sw6hl1dd2x]

More than amazing.. Love you Armando for ever you are a life saver

[@cynide89]

Excellent! Very informative. Diagnosed with h.pylori yesterday after weeks of nausea, cramps and bloating. Starting treatment with 2 antibiotics and PPI, so hopefully not an antibiotic resistant strain.

[@gracehaward5330]

That's so sad to hear you are still suffering from this same situation . Am feeling for you right now, I know of a doctor who can help you get rid of this. He also help me from this same situation , He can also help cure yours permanently

[@pavanpabbireddypavanpabbir1897]

@@gracehaward5330 hi who is the doc?

[@pavanpabbireddypavanpabbir1897]

@@gracehaward5330 hi who is the doc?

[@PankajRajput-cv5rw]

Doc name and address

[@jennyli7749]

Great video...it’s made so much sense to me now about the damage done by H pylori

[@Shak0M]

Awesome video. I love how you teach actual mechanisms and how your videos are not that mainstream to grab likes from maintenance guys or hairdressers. This is proper medical channel for people in this field of work, and well It's been said but I gotta repeat simplicity and unimaginable good visuals take it to the top. Keep up the good work!

[@JoseFernandes-bp6rc]

This was exactly the kind of video I was looking for. Great explanation and presentation. Thank you!

[@Qatadah93]

so taking ppi alone will neutralize the acid, but when your stomach become to alkali, the h pylori is easy to attach into stomach cells thus increase in more hydrochoric acid and inflammation. so better to seek dr to treat more if u got some gastric issue in stomach

[@navaneeth_us]

Top-notch conceptual correlation, beautifully crafted and articulated video. This video is like an oasis of water for a lonely traveler that's been in the desert for far too long.

[@Nuroseed]

watching this currently in nursing school. Congratulations future me, we did it!

[@r0mediddy]

I was diagnosed with this recently after constant burning in my stomach. Antibiotics cleared mine up and I stopped eating raw seafood. So far so good.

[@r0mediddy]

@@LakshmiPoojitha definitely follow up with your doctor. You may need other treatment for the ulcer itself. Also, watch your diet and make sure you’re eating cooked whole foods, and fresh drinking water. Good luck!

[@gilbertotrevino7725]

@@LakshmiPoojitha i hope it goes away with medicine

[@bobbymaxx6457]

@Aluru Lakshmi Poojitha how are you...did you cured from ulcer

[@r0mediddy]

@@LakshmiPoojitha Glad you’re doing better! It’s almost been a year for me and doing much better. I get triggers here and there but only lasts a few hours and maybe 1x a month. Much much better than before.

[@skatedd2451]

I suffered from this condition for 30 years of absolute hell at the age of 49 someone had the foresight to realise what I had and now I'm 61 life has never been better thank god to the Australian scientists actually done the right thing and won a Nobel Prize for it God bless you or Satan which ever 1 you prefer?

[@skatedd2451]

, 😎

[@enaaggarao2799]

AWESOME I LOVE THAT YOU TAKE YOUR TIME TO MAKE THESE EDUCATIONAL VIDEOS!

[@2013Queen]

I share your videos with nursing students you explain in such detail! Great videos.

[@UzTibbiyot]

Easy to digest lessons.Big thanks. Personally I'm waiting more and more from you especially clinical pharmacology

[@elirancohanim8134]

The video is great I would have add the parietal cells and the H K ATPs pump , love your explanation, made it visual for me

[@geidirodriguez3581]

Thank you so much for this video! It was so easy to follow! ❤🎉

[@divanaindah7266]

thank you so much for making this video, really help me as pharmacist student

[@praiseayodele2616]

This is just the best explanation out there for peptic ulcer

[@231MasseyFerguson]

I'm having it bad this evening. So tired. The burping/belching/major diarrhea/stomach making lots of weird noises/hurting under left rib cage & it's real tender when I press where it hurts. I can't leave the house because of this. So miserable I don't know what to do. Please give me the cure to make this go away.

[@tmemore]

Great explanation, so if so many people have it, why only a few develop disease? What makes h pilory to damage some but not others?

[@dakotagreenglovess7134]

Right now, I am being treated with antibiotics for Helicobacter pylori, and I feel very bad. This video helped me to complete the treatment.

[@ReshadSherzad]

PPI is taken to create an alkaline environment for the H.Pylori so it can undergo mitosis, in this state, it is most susceptible to the antibiotics.

[@darkdreamer7592]

I heard that they can't survive natural enviroment from other website.. hence having alkaline enviroment is killing them.. Which one is true?~ can I have your reference?

[@theresageiger584]

@@darkdreamer7592 it crates it

[@Casey_Ezaziel]

Best lecturer ever. Thank you so much for explaining this

[@dromulbaninemohebbi4603]

Ulcers occur in the stomach but can also occur in the duodenum, but why are they more common in the stomach?

[@lisa-azrabroad4137]

WHY? you have a beautifully designed bacterium for a very niche environment, which has been around for a very long time. What is its reason for destroying the epithelial cells? What does it gain from this, except negatives, increase immune response and acid content, both detrimental to the bacterium's existence. Also why do so many people have H.Pylori, especially high populations in developing countries and not suffer from GI ulcers? Last point, why is there a high prevalence of patients successfully treated for H.Pylori infection then later going on to suffer with GORD? Maybe H.Pylori is not usually the gremlin in the gut but is made that way by, modern diets, lifestyle or possibly auto-immune reasons.

[@raypalomarez]

I tested positive for H pylori. My Dr. prescribed me Omeprazole, metro Nidazole, and Tetracycline. I'm in zero pain, but I still have lots of bloating. My liver results are good my colonoscopy was normal. I'm thinking I'm going to need to visit a gastroenterologist. It doesn't matter if I eat greens and water only, I still get very bloated. I look like a blowfish after eating or drinking anything. The only positive about cutting out carbs and sugar is weight loss.

[@michaelchristopher3227]

Did they give you a reason for why this happens? My father is in the hospital with this thank you!

[@lizzielonglegs1980]

Thanks for this easy to learn video for quite a complicated subjected to try and grasp for the normal non medical layman/woman! I am waiting tor H PYLORI tests to come back, have had gastritis, ulcers and severe back pain . thankfully using some super enzymes before my meals is helping a lot with my symptoms :)

[@0ddddduck]

Can I ask what type of enzymes you were talking about here? I hope that you have found some answers and have got some relief and healing!

[@johncooper7242]

fantastic explanation thank you for producing this video . clear and concise easy to follow with enough detail to explain but not confuse .

[@paragjindal428]

Can you send the white board screenshot of whole video at last

[@isaacchase564]

Tbh it looks like a animated prezi template and not a real time lapse drawing they used these to sell enlargement pills back in 2010 lol

[@diegomoretto6413]

you simply explained to me in 10 minutes of video what I was looking for in several pages of the pathophysiology book. Tks, you were amazing!

[@SuperBeetox]

Well explained, simplied visualization. Perfect presentation! Please make more!🙂

[@kawtharabdul-gs9oq]

It’s the most wonderful explanation I’ve ever seen ,,✨♥️

[@user-vv6cb9vo7d]

there are no goblet cells in normal gastric epithelium. The appearance of goblet cells in gastric epithelium is an indicator of potential malignant progression toward adenocarcinoma.

[@abdullahalazzawi5077]

Hi, I just wanted to ask - How is H. pylori is able to break down the mucus layer that is covering the epithelial cells which then allows HCl to leak through? Thanks, great video otherwise.

[@daniellefrank1332]

So good. Exactly what I was looking for. Thanks that was so clear and aesthetically pleasing to look at :)

[@waugaure2113]

I love all your videos they are very easy to understand with those artistic diagrams. Keep it up

[@pau6710]

well, this stimulates my brain to learn more, even though english is not my native language, thank you so much

[@mrmeach1967]

5:46 CagA and VacA can cause leaky gut.

[@Hydroxy-yc5fk]

Hallo, die Magenschleimhautentzündung oder auch Gastritis genannt, kann schnell chronisch werden. Dann ist die Versorgung mit Magnesium, Zink und B12 gehemmt. Das hat massive Auswirkungen auf die weiteren biologischen Vorgänge im Körper. Es gibt 3 Formen der Gastritis. Die häufigste G. ist der Heliobacter Pylori, der die Schleimhäute angreift. Es kann dann nach und nach zu Tumoren führen ( Ulcus ). Die tunnelblickäugigen, evidenzbasierten „ Weißkittel“ kennen da nur Medikamente für Symptompfuscherei und machen alles viel schlimmer. Dadurch ( PPI / Antibiotika usw, ) wird der nitrosative Stress gefördert, B12 kann nicht mehr aufgenommen werden, die Mitochondrien werden geschädigt usw. Wer schon PPI nimmt sollte, muss dann schon B12 spritzen !!! Die Magensäure ist ja von Mutter Natur aus sauer gemacht, da Bakterien abgetötet werden sollen. Kommen PPI … Magen nicht mehr sauer, Bakterien im Darm und die Infekte des Darmes kommen automatisch. Das Problem bei den PPI ist, das vermehrt Gastrin gebildet wird. Die Magenwände verdicken und es kann zu gastrinbildenden Tumoren kommen. Die Frage hier ist auch, ob Sodbrennen da ist ??? Der Heliobacter, der die Magenschleimhaut angreift, braucht auch Energie. Dafür braucht er ein spezielles Enzym, die Urease ! UND diese kann durch Vitamin C gehemmt werden ( in der Magenschleimhaut ist 30 x mehr Vit C als im Blut ). Insofern ist die Entzündung ein Vit C Mangel !!! Das kann man mit Vit C als Calciumascorbat und Vitamin E regeln. Dazu die Ernährung anpassen (Pflanzenstoffe wie Alliin im Knoblauch ), nichts Gepökeltes, Geräuchertes, Nitrate in Salaten … ) Absolut wichtig erst den D3 Spiegel mit den Cofaktoren hochfahren, damit der Stoffwechsel in Fahrt kommt ( ausserdem kann der Körper dann seine antimikrobiellen Peptide gegen Viren, Bakterien, Hefen und Pilze bilden), dann die Vitalstoffe, die dir durch die viele Chemie verloren gegangen sind. Bei Fragen …

[@tureckij]

Great videos Armando. I want to suggest my logic here for treating HPilory bugs. However I dont have medical degree, but typical treatment against the bug is counterintuitive. My logic is following. If HCL level would be normal, which is the case for healthy person, bug would not appear and survive in the stomach. I dont believe HP penetration through the mucus can be very quick. So surrounding medium have to give bug a chance to do the job effectively. When ulceration is present, for what ever reason, bug in this case, body is increasing HCL production to protect surrounding tissues and blood stream (I suppose?) from bacteria's. So in my opinion introducing anti acid agents is incorrect. Antibiotics are indeed killing bugs, but its like atom bomb, which is wiping all around, even good bacteria's. So there is nothing to protect the stomach anymore. What should be done I think, is introduction of proper probiotics, correct diet (sulfur containing and alkaline foods with correct composition of spices, proper water with highly negative redox level, good fats - technically they should protect open ulcers from harsh HCL, besides polyphenonls might work against the bugs) and exercises (you need good blood oxygenation). All this should be much easier and much more effective. What you think?

[@zenithironside7864]

I wish this question would be answered especially because that is my concern too and I want to treat it in myself the best way

[@MegaDjspike]

@@zenithironside7864 you got tested for h.pylori?

[@Yoa-er5hs]

@@zenithironside7864 Vete al canal de metabolismotv de franksuarez. Allí encontrarás la respuesta y hasta te contestan. El fué un médico naturista.

[@Noface678]

@@zenithironside7864 did you treat it without antibiotics. I was diagnosed today even tho my symptoms have started to diminished I was still prescribed medicine and I don’t want it to f up my intestines.

[@nareshsapkota]

good explaination but isnt it? antrum( only have pyloric gland ) produces only gastrin in secretion which will induce parietal cell( produce only by oxyntic gland present in fundus and body part of stomach) to produce hcl??? your explanation is quite contradictory , am i wrong??

[@karenbaldry8096]

Thank you so much. Excellent explanation.

[@betzy94]

Thanks for the great explanation. I just got diagnosed with this for the second time and the side effects of antibiotics is killing me ;(

[@raspbrrypie9335]

I hope you are clear and feeling better now!

[@roxcyn]

Feel better!

[@betzy94]

@@roxcyn thank you! I am again on antibiotics for the third time!! Let’s hope this is the last time 🙃

[@roxcyn]

@@betzy94 - I have had them twice and I know the feeling.

[@barbaraosei7955]

Thank you

[@Elinlois1]

Excellent - very helpful for my ANP exams -thank you

[@azlxx9868]

THANK YOU SO MUCH!! This is so helpful!

[@hellenloureiro7801]

Obrigada! O vídeo foi muito bem feito, parabéns! 😊

[@trillionsam2428]

Seriously hellen?

[@laurenx3626]

Amazing explanation, well done 👍

[@ghazwanalmobasher6253]

can i ask you how the histamin act on the pyloric cells

[@doctorofmedicine1113]

Urea breath test can came + ve as H.pylori is commensal..... Any way thanks to u

[@triciacaballegan6076]

My mother is doing a treatment right now but he still very sick😭🙏

[@roxcyn]

I hope she gets better.

[@LotusLumiere888]

Does it thrive in acidic or alkaline environment? Thank you for such explanation! 🙏

[@jehgelo]

Omg This is very helpful! Thank you

[@debbietaputu9530]

Brillant video, confirmed my understanding in the text that im reading.. Thank you

[@annanepunda2569]

Amazing... you make life a whole lot better for me!

[@ub6ib9kc]

Thank you - that was actually super brilliant!

[@RoxaneSmith123]

You are a great teacher. Thank you

[@trinhhien6567]

thank so much for your chanel.highly easy to understand😍😍😍😍

[@jacquelinedelacruz9783]

PERFECT!! I LOVE IT

[@andreagranata4405]

excellent explanation

[@VanillaAttila]

Can Helicobacter pylori cause a low Neutrophil count?

[@anjalachaware742]

fantastic , things easily explained. Thanks

[@AhmadSalman1]

My exam today! Thanks so much for this!

[@UmmSalyama]

The best explanation I love this drawing

[@richatgreenday]

Thanks for the explanation of H-pylori

[@lilbaby123ist]

thank you for this video. it really helped with my exam

[@gayleswellness2225]

Uease turns urea alkaline---lowering the acidic environment of the stomach----less stomach acid--impairing the digestion and absorption of vitamins and minerals--leading to symptoms.

[@ranibabybaby9159]

nice presentation

[@victorfigueroa2934]

Thanks your videos are the best

[@frederiquel7022]

Hi! I just wanted to know if you'd ever consider creating a book with all of your full drawings? Instead of or in addition of selling them one by one? :)

[@jddasadia]

Best channal thnks I passed out many exam by watching ur videos... Thnks alot sir for ur video's

[@gimmeakissbro]

+jay Dasadia Oh god Armando what hypnotization are you inducing through these videos?!!?

[@DC-qk7hx]

Extremely helpful, thank you!!