Intermittent Fasting: A Fast Heart Death?

[@BenderRodriguez-yn1cl]

I’ve eaten within an 8-hour window for years, and am now dead.

[@KotobukiGirl]

Did you write as succinctly in life?

[@BenderRodriguez-yn1cl]

@@KotobukiGirl [curtly] yes

[@andrewnorris5415]

This is his bot that he paid an AI corp to continue spreading his views after he died lol

[@MoonBeams777]

lol I actually laughed and it snapped me out of my mindless scrolling through the comments. I thank you 🎉

[@teliph3U]

Funny joke but I think people using anecdotes in scientific arguments have already lost the argument.

[@luiggiluiggi9023]

Also worth mentioning the survey data collected is of several years but they did not concluded these people were fasting by looking at the responses of every single day of those years, they only chose 2 days (yes only 2 days) of 15 years (5000+ days) of data and based on those 2 days they concluded these people were fasting because they skipped breakfast or ate only during certain hours, only using this as a reference to conclude fasting caused health problems is strange, it should be more rigorous. Especially since they don't know what these people were eating when not fasting, regardless of anyone's opinion on fasting this conclusion is weak at best. Authors themselves commented these results could be caused by the diet and not fasting, reverse causality. So these headlines make no sense.

[@tammyjoma]

But how can they deduce the 15-year results from a two-day sample? I really don't understand how this could possibly be considered accurate. There seems to be a discrepancy between this video and the strange way of doing the study. I saw another video by a doctor who was skeptical because of that brief 2-day window. I admit I am confused about whether to take this study seriously and the assumption that people are dying at a higher rate because of intermittent fasting as opposed to many other factors. Is there not a plethora of studies affirming intermittent fasting? Another example of studies contradicting each other. Which one is it?

[@Fallenangel_85]

Having participants with an average BMI of 30 really scews the results into the direction of Overeating. If they actually included only people with "normal" meal sizes of below 1000 kcal they'd get vastly different results.

[@mrslnj]

I just assumed the results were due to poor diet quality of people who do IF. All my friends who do IF live on coffee, cream, steak and low carb tortillas. It’s shocking IF was only linked to heart disease.

[@Brukner841]

yeah makes sense

[@user-no2mz9hl4f]

The shocking thing is that many (most?) people actually think those foods are healthy.

[@NapaValleyVegan]

I IF simply because I am almost never hungry in the morning. When I do finally eat my first meal, it is a healthy WFPB vegan diet. Tho I can see how IF can be used by folks with eating disorders or other unhealthy relationships with food.

[@gabl1459]

And don’t forget the eggs and bacon

[@Vind1ctus]

I eat WFPB vegan often doing 17 to 20h daily fasts depending on how busy. It works well enough but I wouldn't consider fasting any where near as impactful as WFPB or especially exercise

[@autumnember7]

Hey Mic! Therapist here: I wanted to correct your comment that bingeing and purging is bulimia; this is a common misconception. Anorexia also has a binge/purge specifier. If someone is bingeing and purging, and have a BMI under 17, they would likely be diagnosed with anorexia with said specifier. With a BMI above 17, they would likely meet criteria for bulimia.

[@mickilicyes5399]

Interesting, thanks for the info!

[@AstonAcademia]

I spotted this too. Otherwise everything else spot on. Great video. Believe Binge Eating Disorder is known as BED.

[@MictheVegan]

Good to know, the message of the video is that there is always nuance and I missed it here lol. Thanks

[@Authorthings]

I did not know that. Thank you!!

[@abbigailcarr2725]

For me I showed signs of binge/purge type anorexia but had a BMI above 17 and what I called a binge apparently like didn’t qualify in terms of sheer caloric numbers so I was dx’d with EDNOS

[@sharonknorr1106]

When I first got into intermittent fasting it was through a group, "One Meal a Day." What bothered me was that the folks doing this were often eating huge, saturated fat heavy meals after fasting for 16 to 20 hours. IF helped me to lose weight, but I did try to keep my meals fairly balanced and healthy. While I do think that long ago this is how we often ate, being forced to fast during times of scarcity and then chowing down when it became available. But often that food was foraged vegetables or berries or fish/game whose meat was relatively lean. Those following OMAD were instead eating foods full of fat and sugar.

[@zencone]

The study is useless imo. Between the confounders, variables, and known unknowns the only thing you can conclude is that you can't conclude anything from this. Nothing to see here.

[@respectkindness-oj6xz]

less meals are reasonable if portions are the same, not compensating with additional quantities

[@Microplastics2]

Hi Mic, love your work - been a vegan since I was 14, I'm 18 now, I fell into the trap of excessive protein consumption but after reading quite a few studies I've realised that I was eating way too much and that (despite what I thought) too much protein can be harmful (and that in general people overestimate how much they need). Could you possibly make a video on protein consumption (and the risks of overconsumption) since the literature is a bit unclear and difficult to wade through? In any case, thank you for all that you do.

[@ryanwellington7493]

If you're eating plants for protein there is no too much because of their poor bioavailability and amino acid distribution

[@tomgoff7887]

Studies seem to show that in humans high animal protein consumption is associated with higher mortality while high plant protein consumption is associated with lower mortality. Animal studies though all seem to suggest that low(er) protein consumption leads to longer life although higher protein consumption was associated with higher reproduction rates. A low protein to carbohydrate ratio was associated with the best results. The ratio delivering the best results (in mice) is similar to that in the traditional Okinawan diet associated with longevity. In humans low carb diets also seem to be associated with higher mortality.

[@kwimms]

If you eat whole foods, you don't have to worry about "protein." It's all fake... foods do not break down into these fake little groups such as protein and fats and carbs etc... foods are whole and must be eaten so... preferably raw.

[@fromeveryting29]

@@ryanwellington7493Those claims have been widely debunked in terms of relevance to human nutrition.

[@elephantintheroom5678]

No-one has answered the question on my mind which was whether the "fasting" was associated with later bedtimes or less hours of sleep. Sleep has such a profound impact on heart attack rates.

[@Fallenangel_85]

That's a funny correlation, why do you think it would affect that at all?

[@Conversations-o7n]

It 100 pct. Effects my sleep negatively

[@Conversations-o7n]

@@Fallenangel_85 circadian rythm all of our organs have a biological clock...

[@Fallenangel_85]

@@Conversations-o7n Sleep is a special topic and everybody is different. For me, my last meal is around 20:00 and I have no issue going to bed that way. It's even bad for me if I eat after that since I'm used to sleeping when my digesting is no longer very active

[@respectkindness-oj6xz]

​@@Fallenangel_85not resting enough while doing constant physical work

[@VeganGorilla555]

Wow, I'm stunned by this. I never eat breakfast simply because eating that early in the morning make me feel nauseous. I'd like to see a study where they test Vegans and intermittent fasting.

[@veganlyncat]

Same. I don’t even begin to feel an appetite until 4-5 hours after waking. 👀

[@fromeveryting29]

Same. I’ve tried so many times to eat breakfast but I just can’t get through the meal. I have no appetite right after waking. I eat 2-3 hours after waking. But I also eat pretty much right before bedtime at midnight, too. I get a lot of quality sleep :)

[@MattAngiono]

Same here. I drink some chai until about 11 or 12 and don't feel hungry at all. Then I have my huge vegan breakfast and wait until dinner. And rarely snack! No dessert either!

[@Anne-ub1nq]

I used to get so much nausea if I ate anything in the morning. But I realized my body just wasn't used to eating at that time, so I had to train it for a week or two to get my body to realize that it was time to release all the biological digestive signals to prepare for the meal at the new time. (Insulin, Ghrelin, etc.) Now I eat a massive oatmeal fruit, nut and seed breakfast everyday and I feel terrible if I don't eat breakfast. The body just needs time to adjust to the new schedule, just like you train your sleep schedule. 👍

[@user-no2mz9hl4f]

I wonder what the results would look like if the subjects ate a whole food plant based diet (or even just a plant based diet) and ate breakfast & lunch, rather than lunch & dinner.

[@TheVigilantStewards]

me too

[@benjaminwingchun9665]

Better

[@MattAngiono]

Sounds interesting. There's a huge amount to parse out here. Eating vegan seems to matter more IMHO

[@rachelgoodkind6545]

Thanks for sharing. I have been a whole food ethical vegan for many years and fully believe in intermittent fasting using healthy whole foods. I think the problem is that some humans may gorge on tons of food at meals, or/and eat the wrong food. Some IF fans only in a 4 hour window. I do not know how they get enough calories, however... We humans do not like to feel deprived. I am a personal fan of an 8-9 hour window of healthy meals and not eating after 4pm. I also read one study that stated most Americans eat regular meals plus snack several times a day.

[@dawert2667]

This finding makes sense to me. I have been in a lab studying ageing in a model organism, nematodes, for 2 years. It seems clear that hormesis, the beneficial, lifespan-increasing effect of minor stress like nutritional stress (fasting), only seems to appear in early developmental stages in the animals, while the same stress kills adults faster.

[@andrewnorris5415]

Seriously stressing nematodes in the lab - is probably rarely reached in humans though. Most humans self regulate. They know when they get excessively cold or excessively hungry. You may have to be a masochist to push yourself that much. Whereas nematodes - can be easily pushed to the limits - and often are in the lab. It's natural being older they will more likely die when pushed to such extreme limits.

[@tsurutom]

Exercise works via the same principle and is clearly beneficial to humans during all stages of life. I'm sorry, but they're nematodes. Study results with rodents or even monkeys often can't be replicated in humans, so claiming this finding to "make sense" because of worms is just aggressively unscientific thinking.

[@leftyfourguns]

Longevity can be directly linked to caloric and specifically protein restriction. Time restricted eating (AKA intermittent fasting) is one of the easiest ways to limit calories

[@vicaya]

Why did you ignore the fact that the

[@jovotszebb367]

He always ignores facts that doesn't fit his agenda. Why are you surprised?

What do you mean by posting this? What is the effect on his conclusions?

[@Custodian123]

Yeah the study has massive flaws.

[@JavedAlam24]

​@@jovotszebb367You sound ridiculous, you clearly didn't watch the video and just react posted when you saw a comment you could jump on. He has no agenda with regard to intermittent fasting.

[@jovotszebb367]

@@JavedAlam24 omg you're so right, I'm sorry for being ridiculous.

[@axalius572]

Yes, I'd dismiss the study. Not snacking until right before bed will not give you a heart attack, period. EVERYONE I know who fasts intermittently does either high fat (you basically have to fast, because the meals are so hard to digest) or skips breakfast and then slams a big meal with a bunch of refined carbs just before bed.

[@lemonstealer2902]

I don't understand how you can't eat in a time window. If I eat before bed I will have stomach aches. My eating window is around 10-12 hours but I sleep 8 hours. Do people eat 24/7?? Everyone does a some form of "fasting" in my opinion.

[@axalius572]

@@lemonstealer2902 Exactly. I eat dinner at 6 and breakfast at 9, so that's 15 hours of non deliberate intermittent fasting. If I eat before bed, it disrupts my sleep. But that is supposed to increase my likelihood for a heart attack??

[@KotobukiGirl]

I've been intermittent fasting for almost a year now. These studies could scare me into having a heart attack!

[@deepakhiranandani6488]

😊

[@samo_sibela]

I've been intermittent fasting my whole adult life and am now 50 and in good health. I have been eating predominantly plantbased diet though.

[@KotobukiGirl]

@@samo_sibela Good on ya! I gave up meat many decades ago and became vegan about four and half years ago. So I think the fasting is serving me well. I'm glad it works for you.

[@sandralison7584]

I didn't even know that 8 hours count as intermittent fasting. As I simply don't like to eat when I am not hungry. And I am only hungry after a minimum 8 hours. I never knew that I was " fasting". I was simply only eating when hungry. And eating something earlier was uncomfortable.

[@samo_sibela]

@@sandralison7584 same.

[@Vezmus1337]

I'm very much into fitness culture. The people most likely to do short window intermittent fasting are: Sumo wrestlers, bodybuilders, ketogenic dieters, and very obese people trying to crash diet. Fasting causes stress, stress doesn't cause fasting. I guarantee it has nothing to do with people working "stressful jobs" or whatever, that's pure speculation.

[@pattheplanter]

I have always been a big fan of eating.

[@lashedbutnotleashed1984]

You must get over that nonsense. Eating will kill you.

[@Stardust713-y6e]

😂😂😂😂😂😂😂😂😂😂😂😂😂😂

[@johncrondis4563]

The study on people that skipped breakfast having more CV risk also smoked more than the rest of the groups and had the highest BMI. Studies on this stuff really need track people eating healthy diets with exercise and no obvious risk factors: do whole food vegans (or maybe for the sake of population size mediterranean) who are physically active and dont smoke or drink have greater risk than those that eat more often? Does meal size and saturated fat play a role? Majority of the people I know that intermittent fast or just only eat within a small window or skip breakfast, usually drink tonnes of coffee, smoke, drink a bit, and are eating processed stuff quickly, and definitely not vegan.

[@andreasrydstrom9112]

Hey Mike! Great video again! About the stress hypothesis: My experience is that some people do like you suggest Mike - eat all day when they are more stressed, some lose appetite (and don't self-soothe with food) so they eat less and at fewer occasions. So my guess is that both types are in this study and the "ledd than 8 hours"-group probably picks up a bunch of the latter. About the "better study because of unintentional IF" - I guess it would depend on how well they control for food quality. If they could do that with great certainty it is a nice natural experiment, otherwise there's a big risk that they also had poorer quality of their food. Another factor which seems important to denote is which time of day where they eating. If there were a lot of shift-workers like Gil suggested, and they had their eating window late in the day or even into the night, their circadian rhythm probably were worse off as well. I would love it if a bunch of the participants of the Framingham Heart study did IF for a long time. That would be super interesting! ;D Thanks again! Cheers from Sweden

[@GreenTea4Me]

Great show! I thought it was really funny that when you were talking about the vitamin supplement , a commercial popped up for "30 beef sticks for 30 dollars". The timing of that was funny!

[@woody3307]

LDL vs Fasting There is probably no A1c type test for LDL levels to show long trend LDL levels, but recently I have discovered that fasting will increase LDL. In the same way that eating a few bananas can briefly raise the blood glucose level and yet be perfectly healthy and normal in a primate we must keep in mind that at some point in the fasting there is a proven increase in LDL of maybe up to 30%. My guess is the increase corresponds with autophagy and is part of the repair process, but is this rise in LDL really indicative of damage or long lasting? Not likely. We have seen plenty of research on the benefits of fasting. It would be most interesting to see how transient the LDL rise can be or a graph of LDL vs hours since eating with a strictly whole plant diet. Currently the pre lipid test advice is that fasting is not necessary for lipid tests if I recall correctly. One wonders if fasting may actually skew the results temporarily upward but without harm to the patient..and possibly benefit??? Again, I'm just guessing and quoting McDougall...but "It's the food!" In a control environment eating the exact same whole plant foods and calories WHAT should we expect in our testing and long term results. Obviously, our primate cousins forage and eat mostly in the earlier part of day and are not up late at night stuffing calories watching TV..unless they are zoo chimps eating pizza, and they don't live too long. In humans there has been a LONG tradition of monastic practice in Asia of eating only til noonish on foods donated for alms, and before modernization there were many long lived healthy monks. Nowadays, in Thailand there is an obesity crisis among monks. The eating window the same, but I have seen the locals making merit bringing them burgers, fries, oily fried foods and soda etc and the monks are now dying of diabetes and heart disease at a very young age. Looks like the faithful are actually killing the young holy men with kindness and would do better giving them rice and beans and vegetables as in the old days!!

[@xCooler88]

Only I can hear is maybe, maybe, maybe, maybe, maybe, maybe, Not pear reviewed. But it is in the news already. Absolutely disgusting.

[@StephenMarkTurner]

An obvious confounder is terrible diets, both before and while doing time restricted feeding. Personally, I stop eating in the early evening, but leave it at that.

[@tsurutom]

They claim to have controlled for those.

[@StephenMarkTurner]

Well, I guess I will continue to listen to the commentary on this over the coming months. @@tsurutom

[@FreedomPhilosophyTV]

Spreading fat intake across more meals will help to reduce the peak lipid concentration in the circulation.

[@HoboGardenerBen]

I'm tired of survery studies being spread around the internet. Without actual research finding a cause, all this does is frighten and confuse people. This kind of study should stay within the research world, help guide research to find causal stuff that is worth sharing with the world.

[@andreae.]

Unfortunately people need the clicks, and anything that sounds counterintuitive will get them... who cares if it leads to harming people? (the Time magazine butter cover should land someone in hell, but probably all it did was increase revenue)

[@HoboGardenerBen]

@@andreae. Yup

[@tofutuesday]

Pet peeve: you can never actually skip breakfast. Breakfast literally is "break the fast" that you were on as you slept. So your first meal of the day is always breakfast whether you eat it at 8 AM or 4 PM, or whether you have pancakes or a sandwich.

[@wildrice8199]

That's not how the word is used. Words can often have a technical meaning and a colloquial one. I would say 99% of the time breakfast is used to mean a meal in the morning. If it's after that, we refer to it as lunch, and if it's in the evening we refer to it as dinner. You will get more puzzled reactions by saying you're having breakfast in the afternoon or evening, than you would if you said you're having lunch/dinner respectively. So ultimately we can't dictate language and how it evolves.

[@bengilkes7676]

Intermittent fasting is not done specifically to lose weight - Mic is making a lot of assumptions today.

[@sandyn7710]

Plenty of people do it specifically to lose weight. I'm sure you could probably find 100+ videos right on KZbin by searching something like "intermittent fasting for weight loss."

[@bengilkes7676]

@@sandyn7710 I agree with you, I'm aware that some people do it to lose weight.

[@akhusal]

Intermittent fasting was unheard of when this study started twenty years ago. Only 400 were intermittent fasting compared to 20,000. Smaller groups have wider variations and when you adjust for many factors the pool of people tested gets smaller and smaller. Plus the starting age was about 40 when heart attacks are very rare. They looked only at two days on average, who knows what happened in the remaining 15 years.

[@VeganLinked]

What were these people eating? And it would be cool to control for a time of day. But also in the context of sleeping patterns. Like Dr Greger has said, eat breakfast like a king, lunch like a Prince, dinner like a pauper. But that can be done in an 8-hour window without having to overindulge.

[@VeganLinked]

Or can it?

[@NickSBailey]

I'm going to reserve judgement until more info comes available, one thing is intermittent fasting shouldn't mean binge eating lol I can't face breakfast never have been able to have it, I.F always seems to give me a clearer head and more energy when I stick to it so I will be disappointed if all this is true, I'm hoping it's some anomaly such as people combining it with keto or carne which are both terrible in the long term

[@harrynac6017]

I did intermittent fasting for yeaears. Not that I ever heard of it, I just felt better by not eating through the day and stuffing my face after work in the evening. "For me every day is Ramadan," as I would like to call it "apart from drinking water and coffee with milk".

[@VeganLinked]

Are you really skipping breakfast when ultimately you're breaking the fast. What exactly makes breakfast different? Eating before 9:00 a.m.? And then getting a little infrared. I think maybe we digest earlier in the day better. But if someone was simply eating whole plant foods, a well-planned variety, and not gorging, why it would matter if they ate within an 8-hour window versus a 10-hour window or 12. Maybe it's indicative of being more active. I wonder what other lifestyle behaviors these people have in common. Is anyone going to tell us what they were eating?

[@KotobukiGirl]

I'm vegan and purposely intermittent fasting. Test me! Test me!

[@trinityangel666]

It would be nice to know what these people were eating. It’s funny how that information was not given. I m guessing they were not vegan.

[@VeganLinked]

@@KotobukiGirl 😂

[@lightningbug276]

IF took my blood pressure from 188/90 To 135/ 80

[@clairbear1234]

Do you think that the kinds of thing you were eating changed? Or your physical activity?

[@xDomxMagicx]

Was this the only thing you did or anything else? And how long do you fast?

[@xcast1]

Via weight loss, changed food types, added exercise / sleep ... ? Or nothing else changed than eating time window?

[@lightningbug276]

I ate Whole Foods, which cut my sodium 🧂 level way down. I cut out caffeine except one cup in the morning.

[@lightningbug276]

I have mobility issues, so I did seated 20 minute workouts.

[@A_Lee87]

Looking at the population of IF eaters it is no surprise, because a lot of sick and fat people do IF for it's (supposed) health benefits and weight loss

[@Marchgirl329]

I don't get the concept of skipping breakfast. As long as you have a first meal SOME time during the day, that's breaking the fast, as in "breakfast". I am up for 2-3 hours before I eat, so does that mean I'm a breakfast skipper?

[@wildrice8199]

If it were 4 hours yes, only 2-3 is borderline. The concept is skipping an early morning meal, assuming you follow a standard "sleep at night" schedule.

[@rod7944]

eating early breakfast meals is a scam brought to us by big cereal @@wildrice8199

[@ambers.]

Thank you! So useful!

[@andrewnorris5415]

It resulting in - 1) eating too much in one meal, 2) eating more overall and esp saturated fat (due to skipping breakfast). Makes most sense - as we already know these are risk factors.

[@tsurutom]

Maybe. You don't know, and neither does anyone else. If we weren't so exceedingly bad at guessing the right answers, we wouldn't need science.

[@bengilkes7676]

It's a good job that one study doesn't negate all the others that say the opposite then.

[@andrewnorris5415]

@@tsurutom as I said, it's what makes the most sense. The other factors, while possible perhaps, are not proven either for or against and could equally be true or untrue in my view

[@gitrdone3770]

Another good video Mic. In case someone hasn't brought up this source on "intermittent fasting", has anyone looked at the years of research at Loma Linda University? The Seventh Day Adventists have been eating within a 8 to 14 hour window for a few generations. In the beginning it was (and is) by scriptural prescription. Adherents still follow this schedule pretty much but most SDA's are no longer plant exclusive (vegan). Dr. Hans Diehl spent his professional career working at Loma Linda U to better understand the ups and downs of the way SDA's live. Considering that the SDA's have over 200 hospitals around the world their data is a more macro perspective than most. I unwittingly began eating a

[@rexmundi9691]

Research into IF in the future is going to be so confuzzled thanks to keto diets, as it is super big in that community. Good luck to anyone trying to untangle that mess.

[@justcarineinparis]

I skip breakfasts, I am just not hungry in the morning, but my meals are on the smaller side (compared to what I see my colleagues eat) and I have banned oil from my cooking. I feel pretty safe 😊 Thank you for sharing the information, Mic ❤

[@f-mon]

If you go to Nutrition Made Simple's YT page the first pinned video is an interview with a doctor who claims you can eat 42 eggs a day and it won't raise your cholesterol levels. Pretty sure their channel isn't a reputable source.

[@woody3307]

Amen...didn't take long more than 2 videos to figure that out.

[@NB-lx6gz]

Oh no... I thought he was reliable source

[@cherylchilds7025]

That’s Dr. Gil Carvalho’s channel-his video’s are excellent, it’s all about the science and explaining these studies-I think he’s great!

[@Vezmus1337]

I sometimes watch his channel for the information he covers. The information is good, but a lot of what he says is personal opinion. Read the information yourself and come to your own conclusions. Not even doctors are without bias.

[@tomgoff7887]

It has long been known that, once dietary cholesterol intake reaches about 400-500 mg per day, any extra dietary cholesterol will not raise blood cholesterol levels. That's how the egg industry knows that, if it funds scientists to investigate whether egg consumption raises blood cholesterol levels, the reserach will find that the answer is "no" as long as they use subjects who are already eating plenty of meat and dairy (ie most Americans).

[@classicgameplay10]

It depends on what meals you skip. If you skip breakfast and eat big meals at night, it is bad.

[@cainen6355]

We also have to take into account that almost universally we see a decrease in appetite in people with serious and terminal illness. This could be a major correlation showing up in this data (if they didn't adjust for it). So it might for example not be accidental intermittent fasting but could also be a symptom manifesting in people with a terminal illness that is about to kill them, which could partly explain these increadibly high mortality rates.

[@aNaturalist]

A couple of years ago I heard Dr. Valter Longo (longevity doctor) say on a podcast that no benefit on longevity was found for the 8 hour feeding window, but the 12 hour window appeared to correlate with longevity.

[@mdwithspirit]

Yes, I agree. We need to investigate further is the point. What isn't recognized is the adrenal/cortisol component. Fasting all day pushes adrenaline and cortisol you do feel better. Eating a lot of fat/meat pushes adrenaline (and damages testosterone levels). Going vegan and substantially decreasing your caloric intake also pushes adrenaline, so ppl feel good initially but crash or lose all their hair. Going carnivore, runs the adrenals and some people feel great. Cold plunging, cryotherapy, and hyperventilation can also run the adrenals and make ppl feel euphoric. Others, with weak adrenals, feel horrible on it. If you're running on adrenaline from IF, you're gonna feel good. And you can keep this up for a while when you're young. But as you get older, the toll on your body from constant cortisol/adrenaline is worse. People saying they've been IF for a while and are ok, is like people snorting cocaine for years and saying they haven't died from it so it's ok.

[@sectionalsofa]

According to Dr Will Bulseiwcz, Plant based GI doc, the microbiome needs a rest and that TRE has a positive effect on the microbiome.

[@HenchHerbivore]

He had also said to me that it can have a detrimental effect and that faster for 24hrs could kill off all beneficial bacteria as they are very short lived. Maybe it depends on the length of fast?

[@Aki-wq6xh]

Good point

[@RoughNeckDelta]

@@HenchHerbivore Yeah, the 24-48 hour fasts never made sense to me because in this period the body hasn't switched to famine mode and will break down protein for carb burning

[@sectionalsofa]

@@HenchHerbivore The positive TRE fasting period he referred to was the standard 12-16 hour fast (most of which is during sleep)

[@ceidrenv387]

He doesn't recommend fasting because it harms the microbiome. Also, he's now a spokesperson for that muffin company (white flour, eggs and all) so I don't take what he says seriously

[@silence1869]

Most of the people I know who eat in a narrower time window skip breakfast, eat a light lunch, followed by two candy bars and pizza and mozzarella sticks for dinner.

[@vioheubach3112]

That sounds very healthy 😁

[@peter5.056]

It entirely depends on what you're eating, not when you eat it. You can't have heart disease if you're living purely on lentils, sweet potatoes, and broccoli, IF or not.

[@annoyedaussie3942]

Also how much you eat. Although less likely it's possible to get fat on beans and potatoes. Under eating is also dangerous. You see some of those malnourished raw and fruitarian vegan types they're heart attacks waiting to happen also.

[@peter5.056]

cardiac arrest from malnourishment, is an entirely different story;)@@annoyedaussie3942

[@bengilkes7676]

Can you name a few that have had heart attacks? Or are they all waiting and waiting for years and years?

[@kwimms]

Only meat heads get heart attacks...

[@TonyMyth]

You can certainly have heart disease eating carbs

[@holographicbreathing]

I have done several 9 day dry fasts feeling wonderful and cleared lyme Disease

[@tamcon72]

This mystified me because I thought the science of intermittent fasting was showing moderate benefits. Hope the researchers go back to examine this issue in a more serious way. Thanks for posting, Mic!

[@lafamillecarrington]

I have been trying a time-restricted eating schedule - by skipping breakfast - and haven't noticed feeling any health benefits. Porridge for breakfast tomorrow!

[@jeffg4686]

I always feel better when eating less. That says something. I eat dried mushrooms a lot when I feel like I need to lose weight. the oyster mushrooms are supposed to be good for weight loss (as well as carnatine and berberine)

[@riverbeee9643]

I'm cherry picking and giving anecdotes, but there's a lot of 30 year old pharmacists having heart attacks and a lot of them are working 12 hour straight without meals.

[@YevKS]

Do not ignore this abstract (different from what a study implies). This abstract is here to remind you that science has become a political tool. And a convincing one at that. But the only thing that applies to you specifically is what you do and how you feel daily. Not what a study says.

[@MagnusSohlberg]

First! No but really, thanks for making awsome content. Will make sure to watch this one thoroughly!

[@gsmusic2009]

When I fast, I actually eat once in that day so I actually fast for 20-24 hours after that!!! I have never really done the 16:8 the way they say where you might eat a ton of food in an 8-hour window!! If I fasted for 16 hours, I still would eat that one meal only and then fast! Thats actually how your gonna lose weight along with exercise!!!

[@sandralison7584]

I was fasting 8 hour windows without knowing that people call that fasting. I wasn't simply hungry enough to eat something. Should I force myself to eat more often? I often can't eat breakfast because its too early in the morning. Most of the times I am not hungry at all in 8 hours. Why should I eat when I am not even hungry?

[@anonimogonzalezperez4951]

the same, I tend to not be hungry at least 12 hours each day, sometimes more. All my life. How can that be bad in any way.

[@MattAngiono]

I think generally it's 16 hours of NOT eating (8 hour eating window) that is considered ketosis or ketogenic and IF

[@nuke291]

this isn't about what you SHOULD do, it's about numbers and it seems like eating all within 8 hours has some things to be concerned about. Your question is like saying "Why should I do exercise when I don't even want to?" xd

[@maximborodyuk3773]

People with

[@sleeplessmax]

I definitely unintentionally did this when i was working a lot, ate no breakfast because my day started early, no lunch because work gets busy or i forget to bring food, and would be too tired to eat when i would get home. So terrible

[@MrQuarksy]

The study in question is low grade data of course. But... the other more reliable studies show a very significant trend showing that skipping breakfast and condensing the eating time frame might be causing more harm than good. I normally skip breakfast, but I will change that idea from now on....because the logic is pretty strong. I've known of cases where people have large feasts like Christmas and have died on boxing day, and that danger is also well documented. The body purposely sends people to sleep after a huge meal, so as to preserve energy and avoid strenuous tasks that might potentially blow the system! Speading things out may be a wiser choice.

[@bastianelken7125]

8:47 "25000 calories over

[@adiohead]

That's me! 🤰

[@v.a.n.e.]

it's probably a mistake. it should be 2500 kcal.

[@plaru5194]

What are your thoughts about 24 or more hours of fasting?

[@agadooska]

What is breakfast? Is it a meal eaten at a certain time of the day or is it a meal eaten a certain amount of time after waking up?

[@dionysusnow]

There's this thing called the sun, it come up every day and your circadian rhythm is attuned to it.

[@agadooska]

​@@dionysusnow The definitions in the scientific papers are inconsistent as to timing and energy content of 'breakfast'. So I'm not sure why is your comment so passive-aggressive?

[@seitanbeatsyourmeat666]

It’s breaking a fast. So it doesn’t matter when, it’s when you break your overnight (sleeping) fast. Technically, if you don’t like to eat when you wake up, “lunch” is actually your breakfast. It’s just a word indicating a behavior

[@agadooska]

​@@seitanbeatsyourmeat666I used to think that too, but I think most studies define it as the first meal max. 2 hours after waking up and before 10 am. But then there is the issue of energy content: if I have white coffee does it class as breakfast or does it have to be more calories, etc. It's one of those things that you think are obvious until you try to define it or do research on it.

[@agadooska]

​@@seitanbeatsyourmeat666but it makes sense linguistically, of course!

[@erastvandoren]

There were a number of "studies" lately binding CVD mortality to all (un)possible causes. All, but one. And I'm not allowed to say which one.

[@jaypalnitkar4400]

Analysis Paralysis. I started IF since 2017. Alive after 7 years 😊

14:35 On the other hand, the less than 8-h window people have the highest tobacco smoking consumption, and in addition, that group also has the largest percentage of black people (23.2% vs. 8.0% overall), the smallest percentage of white people (50.2% vs. 73.3% overall), the highest average BMI (29.9 kg/m2 vs. 28.7 kg/m2 overall) with the highest standard deviation (0.6 vs. 0.1 overall), and the second largest percentage of men (54.8% vs 50.0% overall) only smaller than in the more than 16-h window people (59.0%).

[@andreawisner7358]

Guessing they're dying from taking diet pills and caffeine to avoid eating.

[@hampopper3150]

Since we are on the topic I ate over 6000 calories today and I feel like a god thanks to seed symbiotic!

[@michaelmackey754]

Great video! Thanks! I totally agree. I wake up in the morning and make a big plate of carnivorous vegetables for breakfast, and repeat throughout the day. (fiber is my number one focus and in my world is the (king)

[@Johny40Se7en]

This study sounds so disorganized I don't even know where to begin... First off, why haven't they done a large study on intermittent fasting with a large number or people in different groups to compare if this is the case with a whole foods plant based diet, or is it only corpse and egg munchers, and dairy guzzlers, pescetarian and keto diet? Also lifestyle habits. It would have been way more broad and in depth to do that. Wouldn't surprise me if one or more of those researchers were funded by big pharma to skew the results. 12:30 that's an important bit of information. Shame all of it wasn't as on point as that.

[@deepakhiranandani6488]

I wish the peers had reviewed: Dear peers, please review. Thanks. 🙂. Lots to digest in the video, somehow; probably I shall watch it again reducing the speed. Takeaways for now, for me: another caution on skipping breakfast which I do and on balance shall continue to do but thanks for the cautionary reminder; and heavy meals - albeit fibre rich no sos whole food fully plant based ones - which i shall act on. The thing is, I find my cooking, even without salt, so very delicious, that I eat till I'm stuffed. BMI ok but still, shouldn't eat quite so much at one go. Well thanks, a good video which i shall watch again. I did watch and read some reactions to the study report saying it was self reported and standard diet so not that important, so it's good you gave it a fair hearing, so to say.

[@CheryelHutton]

I can't remember the stats, but there is a major increase in heart attacks on Thanksgiving because of the heavy eating in one meal.

[@freerkteunissen7478]

Great video. Again. Thanks. I have a question. is the presumed higher death rate among people who do TRE or intermitted fasting maybe caused by or linked to exercise. If you have eaten to little or to much you might not have the energy to excercise.

[@VirtueMastery]

Hmmmm..... I skip breakfast and eat 2 meals a day. 75% of the time I eat the same thing (for finances and ease) 950 for lunch and 1200 for dinner. Lunch is a protein dring and granola, oats, strawberries and almond milk; Dinner is 1 kg of potatoes and 100 grams of vegan cheese (20 grams of saturated fat). Now I don't know what to think of this...

[@josephlogan7639]

Interesting, I know that I don’t eat the healthiest when I am in an IF, doing my best to put in healthy foods first but it takes time to find a system that works for me. It is an ongoing learning process. Being vegan is not a guarantee that your diet will be healthy as there are so many vegan options but it definitely helps

[@honsten]

Been doing IF 16/8 since 2016 but not into low-carb or keto stuff, just whole food but with some animal products in the mix. Generally very active and doing it all for the telomeres and autophagy than weight management. Alarming study but didn’t control for diet or lifestyle so I’ll happily continue doing the thing that was considered fine for millennia.

[@steveherridge8965]

You've brushed over your right hand side hair bit. Well done

[@TooManyChis]

Yes, I am a little leery of some of these claims these “experts” are touting about intermittent fasting. I tried it for about 2 weeks and I did lose weight but felt like crap. It did not make me feel energized, quite the opposite.

[@lifeisagift5627]

I always crave fruits when i am fasting. I never crave anything fatty or cooked.

[@hugomarquez3189]

Hi Mic, great job as always, but I have a bone to pick with you about your Complement ad. It’s just not remotely true that you pay more buying the vitamins separately, and I think you know this. 50/month plus another 10 for shipping would be 3 times more than what I pay for my multi plus DHA/EPA (I get 90 pills). Let’s keep it honest. I have nothing against the company, they sell a good product, but they cost more when compared to other options.

[@coloredbymaia6476]

A lot of people who do IF eat cheeseburger’s during their 8 hour window! That is probably the reason

[@Tonimadroni]

So what about someone who eats only lunch, snack, dinner, only eats a whole food plant-based diet, and eats around 2000 cal a day?

[@lorezyra]

HUGE TYPO at 08:45, Should be "2500 calories over

[@Babesinthewood97]

I always thought that it’s the food, exercise and sleep that’s important. Not when you eat. Btw I tried IF for a while. It made me GAIN weight, because I tried unhealthy foods I would never eat otherwise.

[@janefreeman995]

Dr. Longo has claimed that eating in shorter than a 13 hour window in the long term can be hard on the gall bladder.

[@bengilkes7676]

Why?

[@erastvandoren]

Actually, not only that, but also fatty acids elevation in blood.

[@JosefK2275]

Mic, researchers are not placing enough attention on the gut and heart connection which may not be at all related to cholesterol, artery hardening or even heart disease, and no effect from fats/carbs ratios or whatever. I believe many heart attacks are due to a mechanical/ pressure effect on the heart (you did mention this by passing very briefly). Research Roemheld syndrome as it relates to this.

[@northerncoloradotransparen1454]

now the keto/carnivore fantasies can blame their health issues on fasting

[@Edge2177]

Intermittent fasting on a standard American(or chinese) diet is definitely going to be associated with heart disease.

[@godemperormeow8591]

I don't know how I am able to keep working 8 hours a day. These stats look rough. Man, can't wait until half my co-workers drop off like flies.

[@annala2956]

8:46 3000 cal over 12 hours and 25000 cal over

[@mrwizzardknight]

How about you tell us what kind of NONE cultivated plants ARE all totally safe for humans to eat? Cuz obviously all the food you get from the supermarket is all cultivate! 😝😂 And maybe just for a while! Cavemen MIGHT have been herbivores to begin with but damn right not long after that they REALLY liked eating meat! XD

[@TangoMasterclassCom]

As always, your video of a new study analysis is by far the best! Best research from you, lots of new valuable information, and as usual: presented in such an entertaining way. Big fan here!

[@suicune2001]

Thanks!

[@Sukidezu]

Thanks for the dissection; seems like the 3 meals a day happened naturally to avoid heavy eating

[@BigIndianBindi-jy1cz]

i like waiting until the end of the day to eat. if i eat during the day, i get tired/depressed lose motivation and enthusiasm. food is soo bothersome to me. i just leave it for the end of the day so i can eat, and sleep through those symptoms. I have great bloodwork.

[@tsurutom]

How anyone can get tired, depressed and lose motivation after eating an apple or a handful of grapes is beyond me. Maybe you need healthier foods. Your "symptoms" are a much better indicator that something's quite wrong than any bloodwork, which will always be very superficial, because a non-superficial one requires more cost and effort than most people are aware of.

[@BigIndianBindi-jy1cz]

@@tsurutom Thanks for shaming.

[@pavlinahrebackova3000]

That is not good. Food is fuel for body and if you are tired after it, there is something wrong. Have you checked with doctor? Organs? How is your stomach doing? Also food alergies and intolerance? Level of histamine? Please take good care for yourself 🍀

[@BigIndianBindi-jy1cz]

@@pavlinahrebackova3000 I have a dysregulated nervous system from CPTSD (lots of childhood trauma, abuse and neglect) it's just how my nervous system formed, always in fight or flight. and its bothersome for me to eat unless I can rest afterward, and I don't like resting during the day because I like to stay busy. My skin and bloodwork and poop are normal.

[@truthbetold6496]

Every time something comes out, at first its WOW and after no no don't do it. Once again i read this study it makes no sense at all, depending on what you eat during your window, and how can not eating cause heart issues.

[@laura-loves-god]

I personally don't go along with the intermittent fasting vibe. I think that people like most other living creatures are best suited to grazing - eating little and often. Eating one meal, two meals or three meals a day can put quite a heavy burden on the system. And, where did we get this eating meals idea? I guess the same people who brainwashed us into thinking we need to eat only at mealtimes are the ones who claim that 'snacking' between meals is bad....who says?

[@allencaruthers867]

For most of human history, people didn’t have the money to eat multiple times daily, let alone eating every day. I really doubt fasting today would be so troublesome for people’s systems to handle it. Even the Bible comments that fasting is a good thing. I’ve eaten once or twice a day for most of my life since I have been working.

[@philddlesticks]

shorter eating window = binge eating, bigger meals

[@JordanPike]

Thanks Mic! Was really excited to watch this.