7. ChIP-seq Analysis; DNA-protein Interactions

[@hainesjw]

If I hadn't just spent 30 years in storage (yes, it is THAT much of a playground of info theory), I'd probably be jumping into Computational Biology! Thank you so much!

[@alminasocial2676]

Thanks for sharing your talent with us.

[@SJG7590]

This is wonderful. I love this!

[@komaldolasia8251]

Too good, just loved it, explained nicely

[@rosannainturri8092]

Very good and very interesting... the research now needs of this.. free knoledge for all people from different countries.. to go on

[@jingqinluo7493]

Very nice course on ChIP-seq

[@mrpope1941]

What an awesome lecture!!

[@Cfx45321]

Very interesting !!

[@yingeddi2008]

The protein-DNA cross-link is random? The protein has to be of interest, right? I am a bit confused by the PPT showed here. There are triangles and squares.

[@luisvalesilva8931]

The crosslink step is not selective. The protein of interest is targeted later using a specific antibody to pull down the crosslinked protein-DNA molecules.

[@djalitanaful]

thanks for sharing. very helpful

[@水韵-e5i]

Can anyone please tell me what is the function or how can we get the function of p(rn | j) =emp((-1)^Sn * (rn -bj))? Do we get the emp function by fitting a distribution to the observed reads distribution of single binding event? or we have a general theoretical model for this emp, like a certain distribution can explain this event well in theory? is it related to the type of protein we are studying?

[@ginnyli2913]

around 31 min, the iterator i should be m right?

[@jadecheng7483]

Can anyone tell me which software was the professor talking about? Thanks!

[@mitocw]

This course uses the Python programming language. See the course on MIT OpenCourseWare for more details at ocw.mit.edu/7-91JS14. Best wishes on your studies!

[@xiaoxuedeng474]

Great Help!

[@neilmarkim4704]

it's very useful ~

[@naeemtajjak6738]

Please any one can send me Urdu translate lecture of chip sequence

[@ravikshatri555]

C Mc

[@johnstillman2935]

did that girl at 34:21 say does it " like" tell you anything about the actual topology ? " like " I guess there are even morons at MIT