Mitsunobu Reaction - reaction mechanism and experimental procedure

[@NerdyG-v1g]

Thanks for the detaild explanations ;)

[@JadeLivao]

Thanks for the clear and informative video! Great explanation of the Mitsunobu reaction! The detailed breakdown of the mechanism and experimental setup is really helpful for understanding this complex process.

[@NROChemistry]

Glad it was helpful!

[@davidc1450]

You did not have any problems with triphenylphosphine oxide and doing flash chromatography. I usually had to remove that first...by recrystallization of the oxide. There was no ZnCl/methanol method yet.

[@naidasaid7507]

I want to synthesize the ganiothalamine and in my protocol, I have a step where I need to make the mitsunobou reaction. I need more information please.

[@naidasaid7507]

Hello! Can you tell me how much réactifs you used? I mean the quantity of each réactif.