Mk's exam secrets S1E7 (Pediatrics)

[@kelvinmwansa6839]

1. Extra Pulmonary TB 2. Chest Xray, Gastric lavage sputum mcs and Gene xpert 3. Caseous and Granuloma 4. Rifampicin, Isoniazid, ethambutol, pyrazinamide, floroquinolones, injectables and corticosteroids

[@DrMK7]

Awesome

[@fortuneharrison167]

1. Hodgkin lymphoma or Atypical mycobacterial infection 2. Lymph node biopsy, FBC and differentials, geneXpert MIB/RIF 3. Reed sternberg cells Or granulomatous infiltrations with AFB 4. HL - MOPP , TB- RIPE

[@DrMK7]

have you considered disseminated TB/Extrapulmonary TB

[@solomonngoma4787]

1. PTB 2. Gen xpert , sputum culture and microscope , urine LAM , CXR 3. Glanuloma cell 4. Rifampin , isoniazid , ethambutol , parazinamide.

[@DrMK7]

Okay great! Would you consider disseminated TB? Also Hodgkin lymphoma?

[@rachealsiampolomba4294]

Thank you very much, this is very helpful 😊

[@mwakamichelo1873]

Bonus Question. 1. Pulmonary Tuberculosis 2.- GeneXpert -Chest X-ray - Urine LAM 3. Epithelioid cells -central necrosis -Wegeners Granulomatosis 4. Rifampicin, Isoniazid, Ethambutol, Streptomycin.

[@DrMK7]

Awesome Would you consider Hodgkin’s lymphoma?

[@mwakamichelo1873]

@@DrMK7 definitely a brain opener. The symptoms actually do align with Hodgkin’s lymphoma. I would just get stuck on the commonly used drugs.. 😅😅

[@DrMK7]

@@mwakamichelo1873 Yes it does align and you would be stuck on the drugs 😂, also on your diagnosis, why not disseminated tb in view of the Adenitis, heparin shaky and cervical lymphadenopathy?

[@mwakamichelo1873]

@@DrMK7 ohhh.. I limited my diagnosis at pulmonary TB🤔 Disseminated TB it is, right?

[@DrMK7]

@@mwakamichelo1873 yes you did, miliary tb I would have been more inclined to agree perhaps cause it’s a form of disseminated TB Also look up on “Pel ebstein fever” and then tell me if you’ll reconsider or not

[@evaristokunda7668]

Thank you so much

[@DrMK7]

You're most welcome

[@macphersonphiri7711]

I would suggest that in the near future, answers should be written in the comment or description session.

[@DrMK7]

In the later episode the answers where displayed on the screen..

[@yamikanindhlovu4803]

Dr MK 7.. could you please shade light on why sickle cell was matched with gangrene?in the question with the table..

[@DrMK7]

The sickle shaped RBC have tendency to block blood vessels and this can lead to ischemia and therefore gangrene

[@allanchisoya2460]

Dr MK 7, so I read that "meningococcemia" causes meningitis and complications such as "gangrene", deafness, etc. Also that due to autosplenectomy that occurs in "SCD", pts are prone to infections from "encapsulated bacteria" What do you think, with regard to the info you gave on the table?

[@mulengaduminga8577]

What would you see if a lymph node biopsy is done on one with disseminated tb? What is the histopathological appearance?

[@DrMK7]

Caseous necrosis and TB granulomas

[@namakau2985]

notifications gang

[@DrMK7]

Always 🤝🤝🙌🏻

[@namakalamwanahamuntu6605]

Thanks Dr. Mk. I think 1. Military TB 2. Chest x ray, genexpert, if cough is productive sputum AFB, LFTs nd U/Es, FBC w/ differential and HIV test. 3. Caesous necrosis and granuloma. 4. Rifampicin, pyrazinamide, isoniazid nd ethamubol. But I have a question, can we also consider Non hogkins Lymphoma? I think it may also be a lymphoma 🤔

[@DrMK7]

Lymphoma will have a similar presentation, clinically it’s what we consider next if we treat them for TB and they fail to respond, additionally lymphoma has Pel Ebstein cyclical fevers similar to to those of malaria and in the question there is a history of them being treat for malaria

[@namakalamwanahamuntu6605]

@@DrMK7 so in this case, which is the diagnosis?

[@DrMK7]

Disseminated TB is more likely

[@namakalamwanahamuntu6605]

@@DrMK7 thankyou so much Dr. Mk

[@seductive6702]

Excellent 🙌

[@DrMK7]

Thank you 🙌

[@mulengaduminga8577]

What would you see if a lymph node biopsy is done on one with disseminated tb? What is the histopathological appearance?

[@DrMK7]

Casesous necrosis and granulomas