Mucopolysaccharide Storage Disease Type I: Hurler, Hurler-Scheie, and Scheie syndromes

What is mucopolysaccharidosis type I? Mucopolysaccharidosis type I, or MPS I, is a rare genetic metabolic disorder caused by deficiency of a lysosomal enzyme required to break down mucopolysaccharides. The disorder presents as a spectrum ranging from severe forms, classically known as Hurler syndrome, which are associated with life-threatening complications, to attenuated forms, classically known as Scheie syndrome or Hurler-Scheie syndrome.
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[@Aasha383]

I am 17 and i carry this same genetic... My brother passed away at 6 years old he was one out of four kids in our family to contract this condition. Thankyou for sharing this video.

[@forextrading938]

Hello which type of mps do u have. My child is 3 year old. She diagnoses with same mps.

[@Nothing-mg8fm]

Is your child okay or not? Have you found a cure? ​@@forextrading938

[@Nikkif1013]

@@forextrading938 you can be a carrier and not show symptoms. I just found out I’m a carrier and I’m 37. I have a son who’s perfectly fine. It’s when two parents have the gene is when a child is more prone getting it.

[@easymedicinebytmd8247]

got my genetics exam tomorrow so this comes in handy! Thanks!

[@josephde-zordi7324]

Excellent synopsis of a complex condition

[@osmosis]

Thanks, Joseph! 🥰

[@saaratsathoo8366]

You taught better than my biochem teacher

[@aminplaysshit]

thanks a lot, I got to present it tmrow and thats all I need😍

[@user-vv6ig6gn9w]

Thank you! I have just one question- so these mucopolysaccharides are produced and broken down by the same cells ? Does that mean that when the cells have produced and secreted these molecules in extp they break down the rest that are not needed?

[@vickyanand6468]

mps- produced by endoplasmic reticulum and processed modified/released finally by golgi appratus. degraded inside- lysosomes

[@sagarboss2004]

Thanks

[@yaseenabed1397]

I have two children having the same symptoms and health problems and the need to guide and guide to diagnose their condition from I am Iraq

[@balanchaevtukuncho3660]

Perfect

[@renad5517]

Thank you guys

[@hrujulshah9430]

Does this usually cause hepatomegaly?

[@potensvita]

thank you

[@wijdanalmaymuny6617]

Thank you very much

[@osmosis]

Most welcome! 😊

[@rymarodrigues181]

شكرا جزيلا

[@thathsarahettiarachchi6152]

Thanks ❤️

[@Worldkeepers]

Its heparAn sulfate (not heparin)

[@deepwithin6517]

Thank you amazing.

[@osmosis]

Our pleasure! 😊

[@racchurachu7227]

My sister daughter suffering from this MPS 1

[@sarojinisahoo.p]

Hi..i hv same problem with my son.... What z age of the daughter?

[@Nothing-mg8fm]

Did you find a cure or not? ​@@sarojinisahoo.p

[@shahanavm8097]

is she okaay?

[@shahanavm8097]

is she ok now? my child is having mps 2

[@jayantighoruimaji6681]

My 2 year 2 month daughter also suffering from this MPS

[@muhammadjunaidali769]

Awesome

[@shenbas7306]

Please find the medicine for this.🙏🙏🙏🙏

[@sonnyliston-tyson]

thank you for this work

[@osmosis]

You're welcome, Luka! 💕

[@medicoUsamaNaseer99]

Informative ⭐ Ja zaa k Allah

[@user-mr4jb1iv5h]

Sophan allah Thank you so much

[@osmosis]

Most welcome! 😊

[@ahmeddhari2271]

Alph 1 iduronidase

[@yaseenabed1397]

لدي طفلان لديهما نفس الاعراض والمشاكل لكن لحد الآن لم يتم التشخيص😔 انا بحاجة الإرشاد والمساعدة

[@Nothing-mg8fm]

وجدت علاج ام لا؟

[@yaseenabed1397]

@@Nothing-mg8fm لا للأسف لازالت المعاناة

[@Nikkif1013]

Hey genetics testing done.

[@yaseenabed1397]

@@Nikkif1013 No, it is not, because it is expensive and not available in my country, Iraq

[@Nikkif1013]

@@yaseenabed1397 it’s available in the US. Idk if some insurances here covers it. I just had genetics testing done last month and my insurance didn’t cover it, I have to pay $1,800 now out of pocket.. in the long run it’s worth it to know. It showed I was a carrier of Hurler type 1. I have a son now who’s healthy and fine. Just because you’re a carrier doesn’t mean you will pass it on.

[@lequadone]

Eat an organic whole food plant based non OMG

[@tunnelunderoceanblvd777]

early uwu

[@racchurachu7227]

My sister daughter suffering from this MPS 1

[@Nothing-mg8fm]

Is she okay or not? And did you find a cure?

[@Nikkif1013]

That’s sad. I’m sorry to hear. Hopefully you caught it early.