My Personal Experience: 1 Year of Taking SAMe

[@franknorton4529]

I appreciate this video so much man. Hard to come by much information on SaMe. I enjoyed watching your video all the way through. I started taking it a week ago as someone whose never really taken a supplement like this but have needed one for a long time, for feelings of anxiety, depression, low energy levels etc. I have only had a good experience thus far, boost in energy, productivity as well as not feeling as overly sensitive or influenced by sensory stimuli which seems to be helpful. It seems to be the boost I needed thus far. Great resourceful informative video man, well done. Dropped a sub, keep it up.

[@TheAnxiousResistance]

Thanks so much for this comment! I appreciate it a lot. My experience with SAMe sounds pretty similar to yours. Its good stuff and more people need to know about it. Thanks for the sub! More content coming soon.

[@TheAnxiousResistance]

Thank you for your thoughtful comment, and I'm thrilled to hear that you've found the content helpful. It's really promising to hear about your early positive results with SAMe - increased energy, productivity, and a lessening of sensory overwhelm are all potential improvements many seek when they begin taking the supplement. In managing conditions like anxiety and depression, it's crucial to note that everyone's experience differs. Yet, it's encouraging to hear that you've found something that seems to be working for you. Thanks again for your subscription and support; it's much appreciated. I'm committed to delivering informative content on a regular basis. Don't hesitate to share any topics you would like us to cover in the future. Stay tuned for more videos!

[@Keep-on-ok]

I use to have really bad anxiety where I had restless legs and could not stay seated on an airline, which is so dangerous. I follow Dr. Eric Berg and he mentioned that vitamin B1 got rid of his restless legs. I tried it and the effect was really amazing. I now take Benfotiamine daily.

[@for_your_health_drangus]

thank you for your honest and thorough review of this supplement / medication. There are countless 90 second videos of people just telling us Sam-E exists without any personal long term experience or information. As someone who struggles with both depression / anxiety and has tried many supplements and tries to balance their benefit / side effect ratios, this was very helpful

[@ronjacobs8041]

It's very important to take the methylated forms of B6,B9,and B12 while taking sam-e. Thanks for sharing your experience with sam-e 🙂

[@danielleschmidt8555]

Can I ask why? I’m about to start taking it

[@jeremywebster6850]

Hey man, I just wanted to let you know that I appreciate you! This video has been really helpful for me, and I will definitely check out more of your videos. I love hearing people's person experiences, no matter what that is. I'm glad you're feeling better buddy, keep up the good work!

[@barbaraannscarlet7885]

Thanks for this. Heard about SAMe, ages ago, forgot about it. Am Not wanting to take antidepressants for too many reasons. Have struggled with depression since a late teen. Am 65 , active, working, otherwise super healthy! Looking for natural supplements, have tried mushrooms, Medicinal and Psychedelics.They help for sure. Medicinal are gross to take every day ( powder form) Psychedelics micro dose kind of helpful, Heroic doses help for awhile... Recently discovered Niacin is hugely beneficial. Took 500 mg 1st try. Waay too much, flushed huge, BUT I had a great elevated mood day. Cut in half, works great. Also recently started taking Ashwaganda 2x a day. Tincture. Am feeling better. Will check out SAMe. Thankyou again!

[@TheAnxiousResistance]

You're welcome! It sounds like you've been exploring some great natural options for mental health support. SAMe can be a helpful addition for mood and overall mental well-being, so it's worth giving it a try. Just start with a low dose to see how your body responds. Niacin, Ashwagandha, and even medicinal mushrooms can definitely play a role too-it's all about finding the right balance for you. Psychedelics, especially in microdoses or guided settings, can offer benefits, but keep in mind they aren't a fit for everyone and often work best alongside other supportive practices. Glad to hear you're feeling better-keep listening to your body and prioritizing your mental health! You've got this! #TAR

[@Lisa-qg7vc]

I really appreciate this video. I just watched one on this topic with very little detail and it was all just warnings of the dangers of taking it and that is frustrating.

[@TheAnxiousResistance]

Your support means a lot! I'll make sure to keep creating informative and detailed content for you. It can be frustrating when other creators take a hopeless perspective on certain treatments.

[@Keep-on-ok]

I take 400mg of SAMe daily with vitamin B6, B12 and folate. Just started taking it about a week ago.

[@TheAnxiousResistance]

Thank you for sharing your experience! It's always helpful to hear how others are benefiting from certain supplements. I'm guessing it's working pretty well for you then?

[@intermilan6202]

@@TheAnxiousResistanceHi, Thank you for your video! - I have Anxiety & Depression & I’d like to take SAM-e… But my only concern is that I’ve read that it may cause Anxiety…. Did you experience any Anxiety whilst taking SAM-e? Would highly appreciate your feedback - Thanking in advance! 🤚

[@karolinaciucias664]

How are you doing now? Any improvement?

[@Keep-on-ok]

@@karolinaciucias664 My findings. My leg, foot, knee and hip pain was caused by Zolpidem that I had been taking for 3 years. Once I stopped the Zolpidem, I took supplements for nerve pain. Acetyl L-Carnitine, R Alpha Lipoic Acid, Omega 3, Turmeric and NAC. I also started taking Lithium Orotate which really helps with sleep. I no longer take the SAMe but I do take B vitamins and folate.

[@Keep-on-ok]

@@intermilan6202 Try lithium orotate. It’s great. Remember people flocking to the warm water mineral springs? It’s the lithium orotate in the water! It really helps and it’s just a natural mineral we all need.

[@summerlake356]

SAM-e is available without prescription in the EU. On Amazon, Naturitas and serious health food shops.

[@summerlake356]

Maybe it is in the UK that a prescription is needed to buy SAM-e. Else the information you gave about the EU is wrong. I bought the 400 mg strength from multiple EU vendors.

[@TheAnxiousResistance]

Thanks for the updated information. That's nice to know that it's actually easier to get in most of the EU.

[@jennarentz]

I can confirm that in Spain you can get it online from iHerb, Life Extension, Amazon… 👍🏻

[@ammanmai]

Does it work in severe major depression? Do I have to take b12 or b complex? And L methylfolate also together with SAMe

[@nerdbamarich2063]

Thank you as always for helping. I really appreciate you.

[@TheAnxiousResistance]

My pleasure! Have you ever looked into this one before?

[@gif24gt60]

If u cant take methylated b vitamins and want to take sam-e, will taking sam-e with folinic acid and hydroxycobalamin still help reduce homocysteine and peevent any elevation of it by same-e?

[@summerlake356]

I reduced homocysteine from 18 to 10 in approx two months, with SAM-e and methylated B vitamins. Was not aware of the anti- depression properties. Also take Choline, to reduce homocysteine quickly.

[@nancy4366]

I take Az***dus brand. I don't work for the company. 800mg 2x a day without food. I take it for my joints and for mood/anxiety. This has REALLY helped me. It's even helped my sleep! Highly recommend!

[@RJay121]

How well does it work on yur joints. I just started hoping DAMe will repair cartilage from early osteoarthritis in my shoulder that started 😊

[@Dayercast.]

What about TMG with sam e do you have any idea

[@teamplayer1634]

See dr Nicole Cain (ND) video on samE.

[@teskay4469]

Thanks for sharing! I am also on prozac and want to try adding a little SAMe.

[@Kesmeseker122]

You shouldn‘t antidepressiva with SAMe without asking your doctor it can make the serotonin syndrome

[@alexanderkarpenko]

hey man! I'm glad that i found this channel...currently trying to take SAMe as the european version called GEPTRAL (which is actually supposed to be a liver supplement) BUT IT WORKS right away...it gives me great feeling of calm and kinda happiness....I started enjoying little things and feeling great in general (even with my low BMI I see how my weight starts gaining even if i eat the same amounts)....BUT BUT BUT SAMe gives me stomach aches....and it kills me....cause I want to take it. Anything you can suggest maybe? should i try different forms maybe? or it wont matter since its the same medication? maybe some alternative?

[@TheAnxiousResistance]

Hey! So glad you found the channel and that SAMe (GEPTRAL) is helping with your mood and energy-it’s great to hear about those positive changes! Stomach aches can be a common issue with SAMe, but there are a few things you could try. First, consider taking it with food to see if it’s gentler on your stomach. Some people also find that lower doses cause fewer side effects, so you could start with a smaller amount and slowly increase it as tolerated (speak to your doctor about this). There are also enteric-coated versions of SAMe designed to dissolve in the intestine instead of the stomach, which might reduce irritation. Lastly, alternatives like methylfolate, NAC, or a high-quality B-complex could be worth exploring, as they support similar pathways in the body. Be sure to talk to your healthcare provider before switching things up. Hope this helps, and take care of yourself! #TAR

[@alexanderkarpenko]

@@TheAnxiousResistance Thank you so much for your respond and tips for fixing the issue. By the way, have you tried SAMe as a shots OR IV?....cause we have GEPTRAL here in liquid forms. my doc mentioned it might fix the issue with stomach cause it would go in the system avoiding GI track

[@beccabean5770]

Thank you for your review. I have recently been learning about neurotransmitters. I read a very eye opening book on how our food directly affects our brain. The Craving Cure & The Mood Cure by Julia Ross. She has 300 research articles & books linked in the Craving Cure alone. She explains how our food system was altered in the 1970's resulting in obesity, diseases, and moods. Our proteins that come from animals fed corn/grains are cancelling out some of the amino acids we need for building blocks to our health. I highly recommend them.

[@ceptember.]

If you liked that book then you'll love Nutrient Power by Dr William Walsh if the mental aspect of more of interest

[@beccabean5770]

@ceptember. thank you so much for the recommendation. I am looking more into the mental & brain health aspects. I just saw my library has the book so I added it to my list.

[@petaloka1]

Thank you for the excellent video!

[@MSS-vw3bi]

Always supplement methylated B12 and B9 with SAMe - Important !!

[@teamplayer1634]

Why?

[@Keep-on-ok]

Move to Arizona! We have lots of sun! I use to live in western Washington state and the weather there is very depressing. I have to have sun!

[@TheAnxiousResistance]

Arizona sounds amazing! I need that sun in my life too! I've often thought about living there.

[@dhawalkothari8425]

I want to use sam-e for anxiety . What dosage is good for moderate anxiety ? Does it increase anxiety ? What is your recommendation

[@TheAnxiousResistance]

I would start low at 200mg and then work up slowly over weeks. Move up to 400mg after 3 weeks and so on. Do this until you either have bad side effects or get relief from your anxiety.

[@PandaLAG]

Thank you for sharing your experiences...I like Life Extension. They're energetically coated & a very good supplement company.

[@Florida_Mollie]

Your link shows the 200mg unavailable. Are you still taking the 200mg and if so what brand? I’m concerned about brands being counterfeit. I’m also concerned about insomnia so I definitely want to start at a low dose.

[@scottwebb9758]

Have u thought about upping the sam e dosage and quitting the ssris ?

[@Dethofdezire]

Thanks for sharing ❤

[@robertt251]

Have you had your Vitamin D levels tested? Low Vitamin D is associated with seasonal effective disorder.

[@valeriecullins302]

Add a good amount of vit. D to your regiment and a little ashwaganda. About 10,000 milligrams of vitamin D.

[@allisquires7008]

Must correct here, Mcgs or IU

[@LRBP]

How are your levels of vitamin D? Maybe the winter (low sun exposure) is affecting you. Low activity also increases overthinking and rumination. Whish you the best!

[@aprildennis6087]

You're actually supposed to take 800-1600 mg per day for Depression. I started at 400 and went to 800. If you can't sleep take melatonin, or listen to meditation.

[@boomerang0101]

“Listen” to meditation?

[@highlytenacious7608]

I’ve seen some recommendations to take it in the morning to mitigate insomnia

[@Mr.Deko86]

I first took sam-e 15 years ago to help with some dark times. It definitely helped take that constant edge off and calmed my racing thoughts enough to evaluate my situation and to pinpoint activators or "triggers". I was diagnosed with depression and I was scared of the side effects which is why I tried sam-e. Long story short, I found my main cause and broke up with her. Within a month, I felt a huge improvement. I think that many of our issues have a mental/emotional root cause but we choose to ignore it or simply do not realize it.

[@intermilan6202]

@@Mr.Deko86- Hi, Thank you for your comment! May I ask if your Brain felt happy on SAM-e like some antidepressants do?

[@Mr.Deko86]

@@intermilan6202 greetings. I don't know that I would call it happy, but I'm calm. The things that normally trigger me are not phasing me at all. Better for me than taking an ssri(horrible experience years ago). So far so good. I'm also exercising, which helps greatly. Are you taking sam-e as well?

[@The_New_Abnormal_World_Order]

I'm on day 11 of 1600mg and I can't feel anything. Might it start to work soon or does this mean it doesn't work on me??? I don't want to buy any more unless I know it's going to work, because it's ridiculously expensive.

[@TheAnxiousResistance]

That is a pretty hefty dose. I would recommend adding an L-methylfolate supplement as well before quitting. SAMe catalyzes the reaction but if you don't have the proper building materials for the reaction to occur, it's not going to help you. I've done a video on L-methylfolate here: kzbin.info/www/bejne/j32qoWWip8h7aLs

[@khurram3616]

Thanks brother Allah bless you and your family brother

[@AngeLEyes8100]

Can Sam e raise blood pressure?

[@MFLA1999]

It did to me. I read somewhere that potassium will balance it out. Like drinking coconut water if the sam-e raises it.

[@ceptember.]

Undermethylators are intolerant to folate. Look up Dr. William Walsh's work on brain biochemistry

[@Oshri_Sabag]

Thank you for this comment, It’s very important to let people know about Walsh Institute work abut Methylation issues and mental health.

[@ceptember.]

Absolutely! I've benefited MASSIVELY from all of his work. Just this week, I started taking an active form of GABA that he recommended and I can't believe that my lifelong insomnia is finally cured! And my anxiety has lessened, joint and muscle pain is a lot better, and I think I'm starting to have some energy. I had no idea I was this GABA deficient, that most forms of GABA don't work, and that it could affect my muscles this much. Biochemistry should be the foundation of the whole healthcare system @Oshri_Sabag

[@ceptember.]

@Oshri_Sabag Dr. Walsh saves lives. I'm soooo happy to hear that you understand how vital proper methylation is

[@TheLastAndFutureDay]

Did you get any stomach upset with this brand?

[@TheAnxiousResistance]

Occasional diarrhea and gas, but some immodium clears it up for me. No stomach problems though 👍🏼

[@916nene]

Buddies your depression and anxiety is not mental in your case is sentimental and spiritual depression You should see a physic medium They might help with a cleanse I was just like you and I got a cleanse and I never experienced depression m on anxiety again, also staying away from social media helped me and being social never stay at home unless to sleep and rest

[@TheAnxiousResistance]

Thank you for sharing your perspective and experience. While spiritual practices and lifestyle changes can be helpful for some, it’s important to recognize that depression and anxiety are complex mental health conditions that often benefit from evidence-based treatments like therapy or medical support. If someone is struggling, I’d encourage them to consult a licensed mental health professional-support comes in many forms, and finding what works for you is key. Social connection and balance with screen time are great tips as well. Thanks for being part of the conversation! #TAR

[@ImPureBlood]

Ever heard the saying TMG = poor mans SAM-e

[@TheAnxiousResistance]

I've actually never heard of TMG until now. I'm looking into it! Expect a video on it in the future. It's a very interesting supplement. Thanks for bringing it to my attention!

[@AatmapremAarya]

Check, you may have MTHFR mutation as methyl donors ease your anxiety.

[@TheAnxiousResistance]

Thanks for sharing this! MTHFR mutations can affect how the body processes certain nutrients linked to mental health. If you're curious, talk to a healthcare professional about testing and whether methylated vitamins like methylfolate might be helpful. Take care! #TAR

[@selinamelody8]

Have you heard anyone who took this while breast feeding

[@ІгорРябенко-н3ю]

How much you cost? Say your price

[@AA-qf9hm]

Please do not take this shit, if you are not diagnosed with depression. This is truly one of the most terrifying supplements I’ve ever tried.

[@pathforwardcreatives]

How so?

[@TheSuccessEngineer]

Why ?

[@teskay4469]

I read SAMe can trigger mania in people who are bi-polar... so that could cause a nightmarish experience...

[@Kesmeseker122]

Why

[@pathforwardcreatives]

@@Kesmeseker122 I didn't take this, but when I took GABA it really messed me up for like 2 weeks. Felt really really off mentally. There was like a delay in my visual perception. Hard to articulate. The best thing for depression/anxiety isn't supps like these. Best thing is working out and taking stuff like ashwagandha and l-theanine. Also, I use nicotine pouches which helps too. Neuro enhancer, but just don't want to overdo them.

[@jacobiani-js]

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[@TheAnxiousResistance]

Thank you for your comment! If you’re referring to resources or treatments I mentioned, they’re shared to help spread awareness and provide options for those seeking support. Your mental health is important, and I hope the video was helpful! If you have specific questions, feel free to ask.