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Myeloproliferative Neoplasms are clonal hematopoietic disorders caused by genetic mutations in the hematopoietic stem cells that result in expansion, excessive production and accumulation of erythrocytes, granulocytes and platelets. This video will discuss three MPNs which are Chrnic Myelogenous leukemia, Essential Thrombocythemia and Chronic Neutrophilic Leukemia.