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What's puzzling researchers studying Parkinson’s disease? Yoland Smith, PhD, Division Chief, Neuropharmacology and Neurologic Diseases, Emory National Primate Research Center discusses this with John J. Foxe, PhD, director of the Del Monte Institute for Neuroscience at the University of Rochester. Smith seeks to understand the pathophysiology of Parkinson's and characterize changes in the synaptic plasticity of the basal ganglia in normal and pathological conditions. With more than 250 peer-reviewed manuscripts, Smith is a prolific published who is also a senior editor at the European Journal of Neuroscience. He is also passionate about mentorship and discusses why people should have a mentor throughout their careers.