New Medication Approved for Polymyalgia Rheumatica!

In this video, Dr. Diana Girnita, a double certified physician in Rheumatology and Internal medicine, discusses the newest medication just approved for patients with Polymyalgia Rheumatica (PMR). She covers the most common treatment for PMR, the process of tapering down medications, and explores the latest approved treatments that may benefit PMR patients. Learn about the recommended dose for Prednisone and potential side effects of steroids. Dr. Girnita also explains the use of steroid-sparing agents like Methotrexate and newer agents like JAK inhibitors and IL-6 inhibitors. Discover the benefits of Sarilumab and Tocilizumab, two IL-6 inhibitor medications, in achieving remission and reducing relapse rates in PMR patients. Explore other potential treatments and their risks and find comprehensive information to make informed decisions about PMR treatment. Tags: Polymyalgia Rheumatica, PMR, PMR treatment options, new PMR medications, Prednisone, steroid tapering, Sarilumab, Tocilizumab, IL-6 inhibitors, Methotrexate, JAK inhibitors, PMR treatment side effects, PMR relapse, Rituximab, TNF alpha inhibitors.
#polymyalgiarheumatica #polymyalgia #treatmentplan
Chapters
0:00 - 1:23 Intro
1:23 -1:44 What is Polymyalgia Rheumatica or PMR ?
1:45 - 2:13 What is the most common treatment for Polymyalgia Rheumatica PMR ?
2:14 - 3:28 What is the recommended dose for Prednisone ?
3:29 - 4:36 Steroid Side Effects
4:37 - 5:21 Relapsing of Refractory Polymyalgia Rheumatica
5:22 - 6:26 New Treatment Approved for PMR Polymyalgia Rheumatica
6:27 - 8:13 Other Treatment Options for PMR (Tocilizumab, Rituximab, TNF alpha inhibitors)
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👩🏻‍⚕️ About Me: Dr. Diana Girnita is a distinguished, double board-certified physician specializing in Rheumatology and Internal Medicine. Holding a Ph.D. in Immunology and having completed rigorous training at Harvard and other top-tier institutions, her expertise in rheumatology is unparalleled. 🎓🏥
🔬 Rheumatologist OnCall, a pioneering platform offering cutting-edge, integrative rheumatology care to democratize access to specialized healthcare. 🌐
🎯 Dr. Girnita's unique focus on Rheumatoid Arthritis (RA) allows for personalized, multi-disciplinary treatment plans beyond pharmacotherapy. Integrating nutrition 🥦, physical activity 🏋️‍♀️, and stress management techniques 🧘‍♀️, Dr. Girnita aims to empower her patients to live fuller, healthier lives. 🌱
⚠️ Disclaimer: This video and its content are for general informational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Views expressed in comments are those of the individuals and do not reflect the opinion of Rheumatologist OnCall. 📜
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Thank you!
Dr G

[@timmurphy3609]

One other problem with long term prednisone is potential adrenal insufficiency. Your cortisol level could drop which makes you feel worse than the PMR. The cause of low cortisol levels is also the cure.....more prednisone. They can't give you a hormonal test until your down to 5 mg. Its a very frustrating dilemma.

[@user-hn9iw2we6x]

It hasn't been officially diagnosed but I'm 90% sure I have PMR. 73 y/o retired physician. This talk was hugely helpful thank you!

[@rheumatologistoncall]

Glad it was helpful!

[@rheumatologistoncall]

Let me know if I can help you with anything

[@momajugy1]

As a dr. Which new medicine do you think is the safest way to go?

[@nonnalovepriceless]

Yes docter I have this and also fybromyalgia I hope there are new treatments coz I’m in so much pain ❤ Thankyou dr

[@rheumatologistoncall]

hang in there!

[@tessmoks3434]

This is great! I was diagnosed with this and I've seen several doctors here in Virginia and they have no idea what that is even though it's in my records from my Dr I saw in Maryland. He was top notch and as of 2 years ago was offered a position at the N I H . I however became allergic to big dose 25 MG dosage of prednisone when I was given it for my severe inflammation. My face turned red I couldn't breathe my face and eyes swelled. But ive those little boxes of steroids where you take 5 one day then 4 then 3 etc and never had a problem.. so I don't know. All I know is I'm not taking those again. I had severe head pain too. I wish you practiced in Virginia. I've been fighting this stuff for 15 years

[@rheumatologistoncall]

Thank you for sharing your experience! It's frustrating when doctors don't have the answers we need. Hang in there, and I hope you find the right solution soon.

[@williammorton2621]

Dr great summary of PMR .I had it and was treated with prednisone which helped greatly but I wish I was offered some of the newer meds that you mentioned during the tapering process. I wish I could have seen you.Keep up the good work.

[@rheumatologistoncall]

Thank you for sharing your experience! I'm glad to hear that prednisone helped you, and I appreciate your feedback on the newer meds.

[@agvision09]

Is your PMR gone after being treated with prednisone? Thank you.

[@cathybarber357]

I was just diagnosed this morning. I’m 59, which took my docs by surprise.

[@rheumatologistoncall]

I'm sorry to hear about your diagnosis. Stay strong.

[@EricSmith-pj2vu]

5:24 thank you for your video, it gave me hope that I can continue to work with the right treatment.

[@rheumatologistoncall]

thank you for watching

[@mirjana182]

Hello, l would like to ask a question. I have fatigue, reccurent pericarditis, light proteinuria(180), and amiloid s in blood that is high. Reumatologist, imunologist tests are negative except from ANA. I stay out of breath easily, had cosacki virus earlier. Could all this be because of autoimun reccurent pericarditis or it is because of reuamtologist problem. Thank you in advance.

[@rheumatologistoncall]

Thank you for sharing your experience with us. It's important to seek medical advice from professionals to get a proper diagnosis and treatment. Wishing you all the best in finding the answers you're looking for!

[@nelaandradr3978]

I have been on predisone but my body can only take max 5mg predisone. I start vomiting and have severe reactions like rashes. I was also given 28 injections, 12 of cortisone ( neuro did not tell me which one) and 12 of botox. It helped a bit with the movement of my right arm but i now have lower lip inflammation. And my upper right side of my gums and sinuses are swollen. I take xefo 4mg, have come down from 8mg but when it wears off i am in the same pain. Last week i had conjuntivitis in my right eye. It is my right side that is affected. My right side of face, neck and shoulder. I have tried solumedrol but my body could not take it. I have been referred to a rhuematologist but she can only see me in july. I have tested positive for ankolosing spondylitis.

[@rheumatologistoncall]

Thank you for watching my channel!

[@mirjana182]

Hello, l would like to ask, could Colhicin affect testing for reumatology diseases. If someone takes Colhicin and has to do testing for most reumatology diseases, could Colhicin affect testing? Thank you.

[@rheumatologistoncall]

NO! that will not affect the labs!

[@hillarymcconnell]

Should you taper the prednisone if the pain is still present before taking meds?

[@rheumatologistoncall]

It's always a good idea to consult with your doctor before making any changes to your medication regimen. They will be able to provide you with the best advice based on your specific situation.

[@robinrasmussen647]

Have there been any studies on creatine’s effect on PMR?

[@rheumatologistoncall]

not usually affecting kidneys!

[@LorySmith949]

I started taking creatinine for muscles because I thought it would help my weak muscles. Does it cause kidney problems? Funny my BUN creatinine was high 29. Doc thought it was from inflammation from pmr.

[@user-fb3fd1zs9e]

What cholesterol medication can you take instead of Statins?

[@rheumatologistoncall]

There are several alternatives to statins that your doctor can recommend based on your individual needs and health condition. It's important to consult with a healthcare professional to determine the best medication for you.

[@powertrip1050]

I'm 56, have PMR - since Feb last year...dropped to 7.5mgs prednisone so far, after starting on 17.5mgs...thank goodness for cortisone..At the start, I went 3 months thinking i somehow strained" myself. Idiot. 😄....should be done by end of year.

[@rheumatologistoncall]

Keep pushing through, you're making great progress!

[@nelaandradr3978]

Lip biopsy was positive for chronnic inflammation. They not sure if it is sjorgrens. The doctors have no clue here. My right shoulder stiffens everytime i dont take my xefo.

[@rheumatologistoncall]

I'm sorry to hear that you're going through this uncertainty with your health. It can be frustrating when doctors don't have all the answers. Hang in there and keep advocating for yourself.

[@Cguin]

I wish you lived in Canada❤ . I have had chronic pain and weakness since about 23 years old. My muscles and tendons/ ligaments right down to the bone it feels. Blood tests have always shown inflammation. I was told by on GP that I had fibromyalgia but was never sent to a specialist because of the years it would take to get in. I also have severe spinal stenosis and I am waiting my 5th back surgery. I am good for approx a year then it starts over growing bone and spondilythesis or/ and retrolythesis. I am 55 yrs old and would love to live a pain free day🥲. This has affected my quality of life and caused severe depression. I have had bld work for runaround arthritis and my dr says I don’t have it but have osteoarthritis. The muscular pain is so extreme . If I lift or do even minor strenuous tasks the next day or 3 rd day is very debilitating for long periods of time. I am lost and have no answers. Can you please give your view on this ?Thank you so very much❤

[@rheumatologistoncall]

look at Dr Andrea Furlan Channel, she is in Canada and she can help you! kzbin.info

[@Cguin]

Thank you soooo very much ! U r amazing ! Usually people don’t answer messages but you do ❤️ God Bless🌈🙏❤️