Newly Diagnosed Stage 4

Рет қаралды 17,420

Күн бұрын

Пікірлер: 105

@ThePCRI Ай бұрын

Timestamps: 0:42 What are the different stages of prostate cancer? 2:58 Does the location of lymph node metastasis affect staging? 3:58 Does the number of lymph node metastasis affect staging? 5:06 Does Gleason grade have any bearing on staging? 6:53 How do PSA levels present in those with stage IV cancer? 7:24 How many stage IV patients respond to hormone therapy? 7:52 What category of hormone therapy has the biggest impact on PSA reduction? 9:12 How should patients who are concerned about side effects approach hormone therapy? 11:03 What does stage IV prostate cancer mean for the average patients lifespan? 15:07 What non-hormone therapy treatments are advisable for stage IV? 16:51 In what context is spot radiation usually used in treatment for stage IV cancer? 18:26 What is the difference between "cure" and "remission"? 19:44 Alex's conclusions

@MySteamChannel Ай бұрын

I have stage 4 prostate since 2 years ago...hormone, fasting & diet are my go to's for now...best wishes to everyone from Australia.

@Johnadele28 Ай бұрын

You're doing great, add Ivermectin and Fenbendazole protocols for even a better outcome.

@leonardoalonso6107 24 күн бұрын

⁠⁠@@Johnadele28Hi please explain about this protocols!!! I would like to know more!!! Same here stage 4 trying to have a alternative treatment

@Johnadele28 24 күн бұрын

I'm treating my PC right now and just opened a substack page to make it public. My goal is to help and participate to divulge these alternatives cure possibilities (thousands x cheaper) that no oncologist will talk about. You can follow the link and spread the word.

@KennyBillings-sy1mg 5 күн бұрын

I follow a similar routine and/or regimen. Try to keep my BMI under 24. Focus on getting good sleep, and gut health, Stay very active and Lift weights And also get a sauna 5 to 7 times a week and the cold plunge during the winter months every morning. Keep my dietary protein levels less than 20%. Try to limit my animal, fat and protein. Not afraid of carbs as long as they’re not added sugars in various products.

@umerramey8531 5 күн бұрын

@@Johnadele28 kindley guide my father 75 diagnose PC with PSA 122

@davegillteam Ай бұрын

My psa was 700 on February 2022! I have 4 walkers and 1 wheelchairs in my garage. lol. Then I stated Xtandi and Lupron, my psa is 0.1 right now!! I lift weights 4 to 5 times a week week. My energy is 100x. I sleep 7-8 hrs. I stopped eating, had a little meat anyway. I make and drink 40 ounces of juice everyday!!! I was weighing 90 Lbs on February 2023. Now I’m at 140 Lbs! Amen to my God JESUS! And you guys, I’ve been listening to your videos for 2 years and really kept my mind positive!!! Thank you for all of your help!🙏🙏🙏

@tonyesimaje8003 6 күн бұрын

How did you go about it, please get back to me it’s urgent

@umerramey8531 5 күн бұрын

Kidnley guide

@victorwong1435 Күн бұрын

How long did you take Xtandi and Lupron to get your PSA down to 0.1? I am newly diagnosed with metastatic prostate cancer.

@raydecampos7327 Ай бұрын

PCRI, I can’t thank you enough for your informative videos and support. I was diagnosed with stage four cancer at age 60 and now at age 64 after radiation and (Lupron) hormone therapy I am basically cancer free. I want to stress to others in my position and at my age that throughout their treatment they need to work out with weights and stay as active as possible. I had some complications early on and was not able to, and I subsequently paid the price. Also talk to your radiation specialist’s about radiating your nipples so that your breasts don’t grow. I now have to work extra hard to try to get my body back to where it should be. Again, thank you to PCRI for all you do. Couldn’t have done this without you. I still watch your videos as part of my ongoing recovery process. You are an invaluable gift! 💜

@christined2495 Ай бұрын

My husband was diagnosed stage 4 with spread to lymph nodes by the prostate 6 months ago, he is on hormones ,and just finished 44 days of radiation, his PSA is 0.1 He feels fantastic, has no more fatigue, a few hot flashes but that’s the only side effects . So glad his treatment is over and Blessed he is feeling so well This channel and the Good Doctor has been so helpful and informative when he was first diagnosed, we were able to weed through two not so good specialist , and found a wonderful hospital where he received 100% the best care

@victorwong1435 18 күн бұрын

Congratulations on the quick recovery. I was diagnosed last month with (metastasised) prostate cancer.

@christined2495 18 күн бұрын

victorwong1435 there is so much they can do for prostate cancer now, and the hormones according to which ones the side effects aren’t as devastating as they used to be. One of the drs on my husbands team said that five years ago it would have been a different outcome for my husband, so a lot has changed in five years with treatments. I wish you well and I wish you a swift recovery., I do know that we prayed and are still praying, I have heard never underestimate the power of prayer. The team of drs was amazing, it took my husband 5 months to find the right doctors.. we couldn’t believe how some Drs are so behind in the times, my husband insisted on the pet scan and two doctors wanted to just operate. Thank God for this channel

@j.polishboy4871 Ай бұрын

Stage 4 since 4/23 w/ a 44 psa. Six treatments of Pluvicto & Hormone therapy have been my treatments to date. My psa has been holding steady at 0.02. I feel great. Living life on my terms. God is good!

@dryhumour11 Ай бұрын

Can you detail where you got the treatment - Pluvicto & Hormone therapy thanks

@j.polishboy4871 Ай бұрын

Froedtert hospital in Milwaukee WI. The Pluvicto was part of a trial. It is FDA approved presently as a drug of last resort. The trial i was on wanted to see what happens when you give it to newly diagnosed metastatic prostate cancer patients who have had no previous cancer treatments. Best of luck to you brother.

@victorwong1435 18 күн бұрын

@j.polishboy4871 Wow! Congratulations on your quick recovery. Yes God is good.

@roberthuff3122 21 күн бұрын

🎯 Key points for quick navigation: 00:05 *🎗️ Newly diagnosed stage 4 prostate cancer means the disease has metastasized, but multiple treatment options are still available.* 01:11 *🧩 Prostate cancer staging differs from other cancers, using risk categories (low, intermediate, high) instead of stages 1-4.* 02:33 *⚠️ Stage 4 prostate cancer includes distant metastasis beyond local lymph nodes, often to bones.* 03:41 *🗓️ Prognosis in stage 4 cases depends heavily on response to hormone therapy rather than number of metastases.* 06:15 *🔬 PSMA PET scans improve detection of metastasis, potentially changing treatment plans by verifying whether the disease is truly localized.* 07:24 *🧬 Hormone therapy is highly effective, with around 50% of patients achieving complete remission.* 08:43 *💊 Combination hormonal treatments are now standard for stage 4 prostate cancer due to their effectiveness.* 09:38 *💪 Side effects of hormone therapy are significant but manageable, often less severe than those of chemotherapy.* 12:23 *🕰️ Survival predictions before hormone therapy are inaccurate; patient response to initial treatment offers better insight.* 13:34 *🔄 Numerous treatments exist beyond hormone therapy, including immunotherapy and chemotherapy, which can significantly impact outcomes.* 16:11 *🔍 Spot radiation for oligo-metastatic disease (few metastases) shows promise, especially with advanced imaging techniques.* 18:35 *⏳ Remission is an undetectable PSA for extended periods without therapy, which can indicate a potential cure after 5 years.* 19:31 *⚔️ Prostate cancer with oligo-metastatic disease can achieve extended remissions or cures, often underappreciated in oncology.* 20:48 *📚 Educational resources like combative manuals are valuable for understanding and navigating treatment options for advanced prostate cancer.* 21:24 *🧬 Identifying if immunotherapy is an option can be crucial for advanced prostate cancer treatment.* 22:21 *🎗️ Hormone therapy is effective for many, with some managing symptoms or achieving remission long-term.* 22:34 *🧠 Side effects of hormone therapy, such as loss of sexual interest, can significantly impact mental and emotional well-being.* 23:03 *⚖️ Balancing survival with quality of life is essential; prioritize personal activities and relationships.* 23:59 *💊 Discuss medication options with healthcare providers to maintain sexual health during hormone therapy.* 24:26 *📋 Writing down quality of life priorities can guide discussions with healthcare providers and support groups.* 25:09 *🤝 Support groups are invaluable resources for patients undergoing hormone therapy and can assist with maintaining hope and quality of life.* Made with HARPA AI

@hatemfarhat5489 Ай бұрын

I have stage 4 prostate cancer since 2021..... second generation Hermon & fasting, Mediterranean goody ( diet. ) are the same as you my , also to go for now . I'm blessed. Best wishes from Lebanon.

@korosetatoo4903 4 күн бұрын

Just recieved PET Scan report from Urologist and whilst most pc like 95 percent still in prostate there is a spread just starting on the edges heading for lymph node. next step is radiology to discuss treatment options like radiation and or hormone therapy. Im at that part of the journey to work outthe best treatment options that minimise side effects and working on reducing PSA readings. I have not experience any related symptoms related to my 3A stage and praying the right pathway will be walked. Stay positive and love thy neighbour. Thanks to Dr Sloth and lovely presenter

@philgriswold2133 23 күн бұрын

I believe that this is one of your best videos to date. Alex, your closing was informative and heartfelt. You guys seem to answer every question I have and some I didn't even know to ask. Powerful resource, that you for all you do.

@PatB415 Ай бұрын

My Husband diagnosed @ 77: Stage 3, Gleason 8 & 9. Each round of Hormone therapy bought him 15 mos of life extension each time. At 83, Stage 4, he failed ChemoTaxotere at # 5 of 6 treatments. Gene tested result: BRCA. Received 5 treatments Proton Radiation + 5 mos Talzenna Parp Inhibitor, which drove his Hemoglobin down to a critical 6. The 2 pts blood transfusion drove his PSA up (continuously doubling up to 160's). 2nd round of Talzenna (lower dose), but same result. With another 2 pts blood transfusion, he's back on Chemo (every 3 wks: Jevtana + Carboplatin, and 5 days: Proton Radiation again). He's now 84 & while fatigued, Dr says he's responding well. If this doesn't work, he'll progress to Pluvicto. Trust the process, exercise, diet. I also now pray to a cancer Saint.....Saint Peragrine ! Thanks Dr. Schoz & Alex for keeping us well informed & prepared for the future!

@victorwong1435 18 күн бұрын

I admire your husband's gallant fight with cancer and his triumphs. I am 78, recently diagnosed with metastasised prostate cancer. Have done MRI, bone scan, CT scan. And Biopsy soon. Could you please give me advice on your or your husband's experience? Please let me know if you prefer to write to me in private.

@basileglof3775 Ай бұрын

Respect and thanks to the team at PCRI. I also recommend a book by Dr.Leonard Coldwell , it's called the " The only answer to cancer." You can find many usefull tips and what supplements you should boost your body with. But tankyou to Alex, she has so much empathy for us suffering men.

@daveh893 Ай бұрын

As always, your comments are very helpful. I have been relying on hormone treatments for 5 years and I respond very well to them. My urologist wants me to go for radiation treatments but I don't see the need since I have responded so well. I am also concerned about the side effects of the radiation.

@ronoster2 Ай бұрын

That is interesting. I have had several radiation treatments over 12-14 years and never had any side effects-until this week. I had a second spot radiation on a lymph node two days ago and have a little pain at the location-not bad but it's there. I have three more treatments and I am going to ask my doctor if that is normal and how fast will I recover. I have resisted hormone therapy because I want to avoid the side effects. I am 75 and fairly active: I swim, ride mountain bikes, and coach wrestling (on the mat) as well as walk a mile or two each morning. I have a friend who got Lupron treatment and is suffering from hot flashes still after a year. In 2011 I had 44 expernal radiation treatments over 8 or 9 week period. No side effects at all. About two years ago I had two brachia therapy HDR radiation treatments. I little more invasive and a little short term pain but no side effects. Based on my experience, I would not worry about side effects from radiation but talk to the doc for more info. Good luck, pal.

@davidf9630 Ай бұрын

I have a question… I have stage four prostate cancer and HAD over 100 metastases on my skeleton… as well as my lymph nodes…I have been on a ketogenic diet for 18 months now and I have less than 10 metastases and my lymph nodes are clear of cancer. My question is how impactful is my diet in regards to my cancer? I don’t seem to get a straight answer from anyone in the medical field, except for the occasional diet MAY help but there is no clinical evidence.

@kristinag1610 Ай бұрын

I hope someone replies to you on this. Diet ? Fasting?

@nelsonoliva2119 Ай бұрын

What treatment have you received so far? or are you saying keto has helped reduce your cancer volume? Also do you eat red meat , pork etc as part of your keto diet?

@Mark_Lacey Ай бұрын

David, I'm in the same boat, Stage 4, same extensive mets. Over 12 months most of my bone mets have gone and I've gone from palliative SoC to spot radiation on my prostate and pelvic lymph nodes. I was keto for 9 months before diagnosis so pretty sure that a keto diet won't on it's own prevent PC. I am still keto but I am a great believer in combining SoC with metabolic therapy and have been researching and implementing some of Tom Seyfried's protocols. Got my final spot treatment #28 today. Good luck mate.

@basileglof3775 Ай бұрын

@@davidf9630 Get a book of Dr. Coldwell, he has answers how to fight all Cancers. American Oncologist worked in Berlin Germany. He heals patients by over 90%.

@peterschenk2352 Ай бұрын

Have you been on ADT treatment while on the ketogenic diet? I also have stage 4 and using diet and fasting among other things but struggle getting my ketones up and wondering if my lupron injections are impacting my ketones.

@indydude3367 Ай бұрын

1806 PSA in March 2023. Yes 1806. Following ARASENS protocol. Today, PSA is .046 and I feel fantastic. Not out of the woods yet though.

@edg531 10 күн бұрын

Keep trucking, brother. One day at a time!

@MrFreeze3007 4 күн бұрын

Damn mine was 1200 and I thought it was super high

@tomswoverland Ай бұрын

5 years with stage 4 Gleason 8 no long term remission but still going on. It goes away but as of yet comes back right away. Tired of the continuous treatments. Had 4 spots just targeted in September waiting for results in December not looking forward to more treatments since I have had most. Don’t know if I want to do chemo again and I have had a total of 50 radiation treatments a few targeted treatments isn’t bad but I started off with 44 treatments not much fun. Dr Kwon has been my Dr after I finished the 44. Good luck to all.

@edg531 Ай бұрын

Hang in there, Tom. Wishing only the best for you!

@af31ns 25 күн бұрын

That's a rough road you've been traveling. I don't think you could have a better doc that Dr. Kwon. Keep fighting, all the way to the end!

@victorwong1435 18 күн бұрын

Yes, keep up the fight. God bless you.

@Wayne-yq4xl Ай бұрын

A really relevant and superb video for my stage 4 . Thanks

@jeetujeet27 Ай бұрын

Unfortunately my father prostate cancer is very agressive. It compressed his spinal cord and he is now paralysed below waste ...it's very cruel disease, all of this happened in 8 months only. Prayers to everyone who is fighting 🙏

@af31ns 25 күн бұрын

😪

@Skwarek-wp8dc 9 күн бұрын

Have a look at dr Campbell's videos : fenbendazole and ivermectin...

@ThePCRI Ай бұрын

Combination Therapy: Chemo, Hormone Therapy, and Radiation For Advanced Metastatic | Mark Scholz, MD: kzbin.info/www/bejne/jKPHipeto9Ken7c

@CancerTherapy Ай бұрын

We find solutions! Guy Tenenbaum, Stage 4 cancer Survivor for 6 years.

@jabster58 6 күн бұрын

Can you do another segment on ...is prostate cancer fatal

@mmazkoory3628 Ай бұрын

Thanks again Dr Mark and Alex for this very wonderful informative episode about prostate cancer and its therapies.

@carladerenzy3674 Ай бұрын

Enlightening discussion. I was/am Stage 4 metastatic. PSA was 525. Now 0.1. I'm on Nubeqa and Orgovyx now for 19 months. No new cancer. Had 6 Lutetium infusions. What's your educated view on the possibility of my going off these ADT's and continuing (forever) with my strict dieting exercise? I have built muscle, body fat is 8.7, and all blood work is good. The drugs I'm on are costly also. I'm feeling better than ever, btw.

@af31ns 25 күн бұрын

With stage 4, I don't think you can ever get off the ADT. Why would you risk letting the cancer grow? When it's contained in the prostate, you could, but not when it's throughout your body.

@cyrillekounde8395 11 күн бұрын

Amazing video! Great content😊

@jeanetteshaw5177 Ай бұрын

Thankyou for this very very informative video which answered many of my questions.

@andrewrobertson4061 18 күн бұрын

I have met. prostate cancer for six years. Had biopsy of lower abdominal lymph node -because of stage 3c melanoma- which showed Small Cell Cancer. I haven’t heard or read anything about it being related to prostate cancer. Any reliable info would be great. Medical team on wait and see.

@ThePCRI Ай бұрын

Bone Metastases & Spot Radiation For ProstateCancer | Mark Scholz, MD: kzbin.info/www/bejne/ZmKXgGd8bpxkq5I

@trevorhoskins7643 24 күн бұрын

Trevlrhoskins from trinidad.i had had stage 4 b prodtate cancer

@trevorhoskins7643 24 күн бұрын

I am not on any drug for th last 5 years

@victorwong1435 18 күн бұрын

@@trevorhoskins7643 God bless you.

@ACTIVEPAIR Ай бұрын

Another superb video, thanks 🙏🏽

@ethimself5064 19 күн бұрын

Thought I would mention that - Choosing Supplements For Prostate Cancer - Needs a update

@fredlevinssr3021 Ай бұрын

I seen my doctor and he wants to schedule me for an imaging appointment. My PSA dropped from .5 to .3. He thought it would be lower. He thinks there might be a piece of my prostate that was left behind after my surgery. I didn’t want to wait until another PSA test because if there’s any part of my prostate remaining I want it taken care of as soon as possible. I understand that if that’s the case the possibility of radiation treatments would be the next possible step. Is it possible to have another surgery to remove what’s left or would radiation treatments be the best option? I look forward to seeing each of your presentations!

@mohammadomarkhalid6684 17 күн бұрын

I find these videos very useful and would like to have your opinion on my case. My psa was 48 and scans as well as biopsy indicated that I had a high risk prostate cancer with Gleeson number 10, stage 4, metastasized in bones. My doctor started hormone therapy (lutrate injection and aberatrone tablets). My psa came down to 7.8. Within one month or so of starting the harmone therapy, my oncologist started chemo (docetaxel), and after first dose, my psa has come down to 2.8. My question is whether the approach taken by my oncologist is correct or not. I am 66 years old with good health. Thanks in advance.

@andrewharms2460 Ай бұрын

Please do a talk about Titan penile implant.

@thomashall9641 9 күн бұрын

I had a Coloplast Titan installed in 01/2024 along with a REEMEX Adjustable sling for incontinence. I had both of these installed at the same surgery. I had my first adjustment to the sling this past August and my incontinence has improved by 90%. Now back to the IIP, I am very happy with the Titan and would recommend it to anyone who is beyond hope for natural erections. I have the original pump, (not the One-Touch), and I am satisfied with it now at age 67 but feel it might be more difficult as I get into my 80's. I am planning to beat my Oligometastatic prostate cancer and live to see my grandchildren age. Again, the Coloplast Titan brings me back to as close to normal as possible. Good Luck with your journey!!

@thomashall9641 8 күн бұрын

Dr. Paul Perito has a KZbin show "Meet the Penis" that is very informative. I had my surgery in Chicago at University of Chicago. I will try to answer any of your questions

@reklovjj 12 күн бұрын

While looking for reasons why Red and white blood count

@ThePCRI Ай бұрын

Advanced Prostate Cancer Presentation By Dr. Eugene Kwon: kzbin.info/aero/PLHj3V3RB2V-gMK9TMMGa-OwKp9K4D7TEB

@shus5787 Ай бұрын

Good interview

@ThePCRI Ай бұрын

Treating Side Effects of Hormone Therapy | Mark Scholz, MD: kzbin.info/www/bejne/e5Ddi2CifJuYm7s

@trevorhoskins7643 24 күн бұрын

After 5 years my psa is 0.069.i had 56 radiations and 5 chemos.a negative psma was attempted.the prostate gives off some psa every 3 months.i had started with o.o18.what should i do when the psa reaches 0.1

@ThePCRI Ай бұрын

Genetic and Germline Testing + Q&A | Brian Helfand, MD: kzbin.info/www/bejne/oWXPiKWGl7NpnLc

@alexandrealmeida6278 Ай бұрын

I was recently diagnosed with pc gleason 4+5 with 5 positive pelvic lymph nodes, they say not curable, is that correct? Nothing else, only 5 lymph nodes.

@af31ns 25 күн бұрын

While not curable, I would not delay getting radiation treatment on the pelvic lymph nodes to minimize your cancer. Once it spreads further, radiation might not be an option. Early, effective treatment is your best chance of many more productive years.

@1958zed Ай бұрын

Maybe I'm the exception that makes the rule, but every time you so confidently say "We know that Gleason 6 does not metastasize," (5:09), I cringe. I was diagnosed 14 years ago yesterday at age 52, and the first sign that something was amiss was a palpable mass felt on my prostate. My PSA was 5.0 ng/mL and 11 of 20 cores on my biopsy came back as positive. I was given a Gleason of 3+3. Under your guidelines, I would have been a candidate for active surveillance with a Gleason 6, but I went ahead and had a radical prostatectomy. The pathological Gleason was upgraded to 3+4. Was the biopsy Gleason incorrect? Who knows. My post-surgery PSA remained undetectable for 54 months, and then it came back but it rose so slowly that we watched it. It took 6 years to get to 0.2 ng/nL. At that point, we opted for salvage radiation therapy (SRT) with concurrent androgen deprivation therapy (ADT; six month dose of Eligard). The SRT failed and now, 27 months after the end of SRT, my PSA is up to 0.69 ng/mL, tripling in the last year. I meet with my team Thursday to discuss what's next. BTW, two PSMA PET scans taken at PSAs of 0.22 (before SRT) and 0.37 (after SRT) were inconclusive. Again, I cringe when you say it doesn't metastasize at Gleason 6, because 14 years later after RP and SRT, my PSA is very much alive, well, and increasing. Maybe one more PSMA PET scan at my current level will show that my original Gleason 6 has, in fact, metastasized.

@alliaj1 Ай бұрын

Your biopsy failed ...i have two pathologic biopsy opinions: one have more "3", second have more "4"😊..After RALP 4:3 (4-70%).

@Mari-su3nv Ай бұрын

He is referring to a true 3+3 . Unfortunately many biopsies that suggest that level actually includes some 4 .

@donnavanclarke5453 Ай бұрын

What you have is a biochemical recurrence, that is not the same as a metastasis (spread to different parts of the body).

@1958zed Ай бұрын

@@donnavanclarke5453 One of the frustrating things about prostate cancer is how squishy terms and definitions can be. The National Cancer Institute defines metastasis as, "The spread of cancer cells from the place where they first formed to another part of the body." My prostate-the original location of the cancer-has been gone from my body for nearly 14 years, but we know that the cancer remains and continues to grow. In the strictest interpretation of that definition, you would have to conclude that it's metastatic. But, you're right. In the prostate cancer world, they like to use BCR as sort of a transitionary category between the original cancer and metastasis. "Yeah, your prostate is gone, but the cancer is likely still somewhere in your pelvis, and that's close enough to where the prostate used to be so we won't call it metastatic." I even saw a medical oncologist say that even if it's in your lymph nodes below your navel, it's not metastatic. If it's found above the navel, it's metastatic. And, yes, the National Cancer Institute does specify that formations of new tumors elsewhere are what makes things metastatic. In BCR, we're dealing with microscopic cells who-knows-where in the body so those aren't technically "tumors." But it's still cancer. I know it's all semantics, but from my perspective as a patient, they took out the prostate where the cancer was located. The cancer is still there when it shouldn't be. It's metastatic.