Special Senses | The Phototransduction Cascade

[@HappyLife693]

Six years later and it is still the best on the internet.

[@lividcoffee1962]

You are literally better than all of the professors in my University

[@iceeyhound3866]

Same experience here. It's frustrating and kind of disappointing. This guy is incredible!!

[@Minnie123.__.]

I can't believe I just watched this 42 minute lecture and was engaged the whole time. You are such a great teacher. Thank you so much!

[@ManirBuhariAbbakarAssada]

THE WAY YOU BREAK DOWN ALL THESE COMPLEX ANATOMICAL STRUCTURES INTO SIMPLER FORMS TO FERCILITATE EASY UNDERSTANDING ... ... ... IT'S TRULY AMAZING !!!

[@nadimsheikh]

Never heard a better teaching tutorial - fantastic, crystal clear or as we call in Urdu "Sheesha"

[@kayshaa]

Hehe

[@danielbleykhman1251]

This is extremely enlightening. I can't believe it took me until Neuro to finally watch this (already took Histo, Physio, and Biochem and no professor could make this clear for me).

[@erikmortensen2987]

Hey man, great content! I did find this particular video somewhat lacking on the topic of ON/OFF bipolar cells (in respect to cones) as well as center/surround field ganglion cells. I think this is a central topic to tackling peripheral visual processing and should at least be mentioned if not explained in detail

[@subashchandrabowse2926]

Amazed at his fluency and knowledge on Transduction cascading..

[@burhanco]

Possibly the best video out there that explain vision physiology and phototransduction in particular. Very thorough and virtually a whole chapter in a video. More power!

[@Susamammut123]

you always save me before every single exam- thank you so much for all the effort you are putting into your lectures!!!

[@shuraymsudaysi4925]

Am medical student from Somalia And this video and all ur videos helped me alot. am very grateful for u, thanks Dr ninja. Keep going

[@rileswain]

Taking an intro to neuroscience course and this answered every one of my questions. Thank you so much! Somehow my textbook forgot to mention "why" and "what" happens after the photoreceptors become hyperpolarized. Confused the hell out of me. Now it makes so much sense thanks to your video. Keep up the good work! I look forward to watching your other videos!

[@justjayden642]

You are a well “versed” educator, and incorporate a lot of really useful techniques to make the information absorb easy peasy!

[@Dr-AI]

I really enjoyed your joke about the cells not being bi-polar

[@thesurgeonsanatomy]

Which cells???

[@tejasvisakhamuri1380]

36:28 - The Recap Thank you so much, watching your neurology series, and they’re really helpful.

[@sumitdhingra1619]

thank u baby

[@prajwal_1402]

Thanks

[@menatollasoliman]

As an optometry student, we thank you GREATLY. Incredible, in depth, yet precise. Thank you so so much for this!

[@victoriafarasat4267]

I hope you know how much we all love and appreacite everything that you do. You truly are the ost amazing person on the planet

[@edita3775]

Thank you a million times! Finally, I understood! Trying to learn from my textbook and watching the material provided by the instructor is like walking in the dark tunnel and seeing no light. Just got overwhelmed with all those words on the pages and pages of information, and having no clue what they are trying to tell me. Finally, I get it!! Your videos are a blessing, especially for the ones that study from home and try to make sense of the whole small details in a&p!

[@חויצרפתי-ס8ג]

This is the by far the best explanatin I found in the web for phototrunsduction, it is all so much clear now and I thank you for that!!!

[@morgan2852]

honestly dude you are the best teacher ever. these videos are a game changer.

[@nicemovie1000]

Thank you for this video! You speak so clearly that I can speed it up and go over the video again quicker as a review.

[@elizabethbiddle6313]

So grateful for these videos, especially as a visual learner. Thank you so much! Imma buy me some gear!

[@yenismarcabrera2309]

From the bottom of my heart, God bless you! Thank you for helping me understand what I've been trying to make sense of throughout a whole semester at optometry school lol this and other videos. All your videos from ALL the subjects ROCK!

[@yasaminkh8164]

I'm a psychology student and I watch your videos.Because you cover everything and explain it so well that I can understand it easily.Thank you.

[@srijanap.193]

The way you make the things simplier is just awesome . It's really helpful. Thank you so much😊

[@NinjaNerdOfficial]

+seaz katty so happy we were able to help!

[@Odonta7]

Thank you ...This is mind boggling not just from the process itself and how all this has been determined but how it happens fast enough from I understand as essentially diffusion and how it all evolved most probably from a developing light sensitive area on single cellular organism many millions of years ago. Extremely interesting! Pushing the imagination to the limit and beyond!

[@678uio]

Hey professor I dont know tyis comment will reach to u or not but im just wanna thanks u from all my heart as u do extreme and extreme hard work for students like us who completely rely on u, May Allah be pleased with you

[@mkfoote]

thank you for saving my life in midterm season. this is a great contribution to youtube!

[@alhanoofs8128]

man u explain in simple terms , sequence and u recap to make sure the viewer keeps on tract . which is absolutely amazing . big big thanks !!

[@ForTheLoveOfCows]

My professor is not interacting with our online class so these videos are so helpful to me. Thank you for taking the time to explain things in detail. You really make it easy to follow. Great job!

[@woillusion123]

I'm a vet student and man, this was the finest explanation of this much difficult topic I ever heard. Even well paid profs are not able to break this down so comprehensible.

[@norfede93]

Wow! That´s all I can say. None of my classes in University have been as understandable as your video. Props to you and thank you very much!

[@barbaradonohue4822]

You have no Idea how amazing you are. Seriously. Extremely gifted.

[@giantblob7075]

YOU'RE A GOD SEND - you teach me more than any textbook and lecturer! Thank you so much!

[@frankwm1988]

Your lectures are fantastic! They are detailed yet so clear. Thank you very much!

[@jakephelps4766]

its crazy how much better I learn from some people on youtube more than college professors paid tens of thousands of dollars to get an education from....gotta love it

[@kearley8792]

Amazing presentation, Mr. Ninja. I have watched many of your videos to better understand the materials I'm learning in school. Your presentation and mastery of the subject matter is far above any professor I've had. Thank you!

[@janhavipatil1041]

This was extremely helpful... i can finally understand this process thanks to you .. u simplified it so well thank u so much ... i can't believe this is available for free ❤

[@ahmetbal7948]

i love it!!! I dont even understand how 40 minutes pass.

[@Emily-zx8ld]

You are the only reason I am surviving my neuroscience class right now. Thank you so so so much!!

[@yusra5833]

i want to cry and thankyou and i just want to personally meet you just to say that your efforts and hardwork really matters to us ..thankyou . thankyou so much

[@navisingh9394]

your videos are insanely useful and informative, and easy enough to follow. Thanks and never stop teaching.

[@p.raghuraj2022]

i am addicted to ur way of teaching complicated topics,hats off sir

[@londesimuchimbajnrmd9688]

Preparing for my resident exams,your video sir has been really helpful

[@nicolemumbamarwo595]

Couldn't ask for more... you're the reason why I'll pass my exams... thanks to the moon and back

[@manalemad1589]

how could it be this perfect

[@ridah4419]

Im sorry i dont have a job to donate but i honestly can't believe that GOLD like this is free of cost for students to access. Thankyou.

[@Psil33t]

i like your videos, but i think in this one you missed some stuff... like differentiation between on and off cells and i think for the sake of understanding it would be better to say that rods/cones usually inhibit bipolar cells (with large amount of neurotransmitter) and when light inhibits them, it allows for signal to be transmitted (rather than to say that small amount of neurotransmitter excites the post-synaptic cell). Basically when the thing that inhibits something gets inhibited, the something can create APs. (A - light) --I (B - rods) --I (C-bipolar) = (A) --> (C) --I is inhibition, --> is stimulation Also, it's worth mentioning that horizontal cells and amacrine cells create the lateral inhibition (inhibit light transmission to neurons close to the neuron being stimulated) which improves resolution/acuity keep on trucking!

[@nuggets974]

exactly

[@wolverinezapper88]

Light hyperpolarizes the photoreceptors and they stop releasing glutamate (should have never said, "a little bit of glutamate" very confusing). Which frees the bipolar cells from inhibition, allowing them to release neurotransmitter glutamate onto the ganglion cells. The retinal ganglion cells then transmit signals to the brain via optic nerve.

[@matheuskeocheguerian8734]

@@wolverinezapper88 Well, im confusing now, because images from books show that the releasing of glutamate is decreased, not stopped.

[@k45p3r13]

@@matheuskeocheguerian8734 You are correct. Even when photoreceptors are light saturated, there is some glutamate release (also known as spontaneous miniatureEPSCs or "minis"), most likely induced by spontaneous opening of presynaptic calcium channels.

[@alieskandari633]

Thanks so much for the fantastic quality of the contents. You educate better than instructors both in Iran and the US. ❤

[@laurabalogh6174]

Hello! This is awesome! I am a second year medical student, and this just made my day! Thank you :)

[@angelunar]

Your channel is amazing!! Please keep posting. If I wasnt a student and/or had at least some disposable income I'd love to become a patron. But for now, a thank you is all i could do. :)

[@dr-usman-pak]

The way on which you are giving the lecture i am speechless about that sir❤

[@chandnisingh8707]

Simply wow! Great! Love from India 🙏✨🇮🇳🌹

[@migueltacos1610]

Incredible video. Thank you, sir! Your excitement makes the video be fun to watch. You da man!

[@Aditya_Prabhune]

I am just so happy watching this. This makes the topic seem less tough and more understandable

[@fc_Neny]

Here 6 years after and this is still the best!

[@ninica35]

I love your videos...I am almost to become opthalmology specialist and am studing for final exam, I find your videos easier to study than my books.

[@christinesingleton4413]

I wanted to learn about the function of my eyes and this video helped me i know you love what you do you explained everything Thank you for educating us about our eyes

[@lamarhammond5976]

You are amazing thank you so much! It would have taken me days to understand the mechanisms you described, but you explained it so well in 42 minutes! You are the best!!

[@nandinisharma847]

All your videos are outstanding, filled with plenty of information, easy to understand and retain for a longer duration of time... I wish I could get a common like button to hit all at once.. I have not come across even a single that I did not like or could skip watching. Great work done!! Please keep doing what you are doing... Your work is exceptional. (Kindly make videos on biochemistry and more of org-chemistry as stuff overlaps). Look forward to watching more

[@daniellameighoo8151]

Thank you so much, i am a year one Optometry student and this video covered basically most of my content

[@nishokaramcharan4379]

I have an exam in 5 hours and this man single handedly helped me pass neurosciences

[@prahalord]

Is it just me who watched this video on its entire 42 mins without a break or is there anyone out there

[@progamerz6738]

I watched it at ×2 so i guess its 22 min then

[@jaycims_012]

😊😊😊😊😊😊 ​@@progamerz6738

[@salmaetman5869]

Very thankful for the great work of the whole team

[@medicophilic_girl794]

Thanks for being there for us .

[@melipasanin9126]

Thank you so much for putting so much effort into the videos you guys are making!!! Highly appreciated!!! 🙌🏼 You just made me not hate the vision pathway which I was trying to understand since yesterday! So thank You.

[@tiacrouse390]

Your videos are way more helpful than my physiology professor.

[@sarawithanh6146]

thanks a load for decorticating complex content into easily grasped info

[@gehnatrivedi6686]

May be you aren't aware but indirectly you are working for a good cause thank you ninja nerds you are my saver

[@brettlee6211]

Hey I’m a Manchester Med student and could I ask for you to come by one day and give us all a lecture at some point? Honestly because your lectures are a 100 times better than the crap we’re given over here

[@princemorgan915]

The recap is the best thing ever 😊

[@ogieborosamudiamen5070]

Reading the phototransduction in my book really made my head wanna explode..this video actually made it very understandable or palatable.. Thank u and continue in your good work.. God bless u

[@kendraabdullahi]

You’ve outdone yourself once again!!!

[@naynay3174]

I think this man took that Limitless pill! Wow THANK YOU

[@n2med]

This was by FAR the best explanation of phototransduction; comprehensively reviewing this entire segment from my neurology class nearly 2 years ago. I can't thank you enough for taking the time to make, edit, and post this video!

[@hardwaybutbetter4687]

i am mozambican, and i love your videos ,, thank you brow

[@goodthings6020]

Just watched this as I was curious as to what happens to a photon in the eye, not a medical student, still understood it. Good work

[@shaegonzales6018]

Amazing video!!! This has been incredible and allows me to understand fully the content!!! Thank you all.

[@vidiia]

I'm studying photoreceptors for an assignment at uni and this has been a really informative and engaging video. Thanks loads.

[@IslamK1959]

Excellent presentation and accurate explanation.

[@minoshchib1414]

"PhoTOtranSducTioN" is a lot i can't belive you drew the whole thing out!! Mashallah brother 🔥🔥🔥

[@Redheadedlady55]

~That was amazing to watch this young man explain the complexities of the human eye.🙂

[@thuyminguyen4372]

Thank you for saving me in Optometry school!!

[@josetrujillo738]

Ninja Nerd Online University (With Professor Murphy!) -- A blessing to humanity

[@tommytorres6335]

This is my favorite youtube channel

[@DC-qk7hx]

You sir deserve a medal for this. Like you, I finished the video with a "holy crap" too. but thank you!

[@hridoymojumder7016]

amazing video. your video is really understandable. I am an optometrist student and I watch your all ophthalmic related videos. Each video is so nice keep it up sir

[@keerthana_mahi8172]

Thanks a lot Dr. Zach It all makes sense now to me 😇😇🙏

[@Mmmyea645]

You deserve 1M more subscribers!!! Your content is invaluable and helped me so much thru uni :)))

[@harshitgupta2471]

you really make the locdown productive,love you loads

[@annamalinowska8183]

thank you Professor Zach, because of this video I passed the exam :D

[@angelmercado1014]

Great video man. I was sure to subscribe. One thing though.. I would emphasize that when the rod cell takes part in hyperpolarization, it becomes less positive or negative RELATIVE to the outside of the cell.

[@jagparmar707]

You are too good. So organized. Thank you very much.

[@juikaiwang]

Thank you for such a wonderful lecture. Best Christmas gift this year!

[@leenbeida1880]

This is incredibly helpful, and btw your enthusiasm is priceless 👏🏻👏🏻

[@stormykook]

absolutely wonderful lecture on phototransduction. thank you for that!!!

[@ughsirius]

THANK YOU SO MUCH ZACH

[@A.Hemashreeanand]

U are really really so Great sir...🙏!!! Very complex topics into so simple one 🙏.. ..sir !!not only in one subjects ....you are rocking in all the subjects🔥 ...sir ..real ninja warrior 😎sir!! With great respect from india🛐...💥

[@robertjonasson2527]

I love your lectures! There are no analog systems in the body. Our brains are massively parallel biologically driven digital processors! Our 5 senses are peripheral systems feeding into it. In your Special Senses lecture you illustrated the wiring diagram of the focus and iris servo feedback loops which are critically damped. I love your series!!!

[@AsmaAlshaykhi-tw4zm]

Always his board like work of art ✨!!!