Reproductive System | Fertilization

[@awokesamuel4068]

Sir, you are the best ever, sir please don't stop uploading videos, we all Nigerian medical students are impressed to have you, you are a blessing to all medical students of the world, please keep uploading much of embryology videos, like, respiratory, urogenital,cardiovascular, nervous integumentary ,and musculoskeletal system development, embryology of ear, eye, head and neck embryology, and finally birth defects and signaling pathways and molecules, like wnt, hedgehog, fgfs etc

[@samirnacer9206]

This comment aged well

[@noorullahahmadi1465]

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[@vidyamishra7738]

@@Nature_r-n6v nice

[@lalanram2570]

Hh

[@victorokiemo]

5 years has passed....wonderful

[@aasemahsan]

9:24 Changes in sperm for fertilization 1) *Capacitation* -Cleans head -Increases motility 2) *Acrosomal reaction* 3) *Fast block to polyspermy* 4) *Slow block to polyspermy*

[@dr.chris8]

I'm in my 6th year of medical school now. I am watching this to refresh my memory and I just can't help it but smile at how much I used to watch your videos back in the day. Thank you bro ❤

[@cymerkincaid1707]

I'm watching this 6 years after production and it is amazing how far Ninja Nerds have come❤

[@גלעדצביאלי]

I don't usually comment on videos, not even on those I like. But you deserve some thumbs up man. Thank you so much!!

[@زهراءحسن-ذ4ل]

this comment is actually funny

[@muhammaddewanggaputralaksa7850]

I Agree with u man, he deserve it

[@mariaaguilar9622]

9

[@aanandkumarclass5703]

@@mariaaguilar9622 ajwal kya hai

[@medstudding2760]

כן אהה הוא אחד מ הטובים

[@lahbabiyoussef6911]

didn't attend embryology class this semester, now im getting more knowledge of the course than i would have from my professor, your are truly a hero. Big thanks from Morocco.

[@HorebVillena]

you’re

[@HorebVillena]

you

[@ሳሙኤልኤርትራዊ]

Honestly, you are the best educator I have ever seen in my life. Keep the good job and I wish you all the best in your life.

[@cosmictask781]

I've watched dozens of fertilization discussion. This is by far the most thorough. It helped me digest all the other information. Thank you, thank you.

[@vijethaaneesh7472]

Summary- Changes in the sperm- 1. Capacitation- alteration in glycoprotein and seminal proteins that coat the spermatozoal head. Occurs in the uterus Increases motility 2. Acrosomal reaction- The sperm has specific protein that bind to the zona pellucida receptors ,ZP3. Upon binding, acrosomal head opens releasing acrosin and proteases. This creates a hole in zona pellucida. 3. Fast block to polysperny- As the sperm touches the cell membrane, Na+ influx occurs . 4. Slow block to polyspermy- Smooth ER releases Ca2+ ions which activates lysosome to fuse with the cell membrane of occytes. Hydrolytic enzymes are secreted causing degradation of Zp3 proteins and hardeining of cell membrane.

[@muhammaddewanggaputralaksa7850]

I have to pay 1.800 dollars for attending the med school per semester, and here i just got lectures for free... Thanks a lot zach and team, i love you guys, god bless you all👍

[@haku0103]

Outstanding. One of the best medical videos here in the web!

[@NinjaNerdOfficial]

+Dan Co thanks man I really appreciate it

[@haku0103]

Haha studying female repro in med school right now. Honestly, your presentation contains so many details i missed just by reading the books. Superb drawing btw! You also seem like a master speaker of the subject, this truly is a gold video. Thanks man!

[@shyla2smoothneighbors32]

Dyan🤙🤛🤛✊👊✌👍🙌🙏🤘🤘

[@shyla2smoothneighbors32]

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[@shyla2smoothneighbors32]

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[@shiv117vikas6]

This guys is one of the best medical teacher in the whole world !!

[@hanoonradwan4874]

you made medicine so much easy on me. You're vids are my best friends while studying

[@TrulyBelieber]

I love how you add a lot of details and still make everything really understandable, thanks :)

[@NinjaNerdOfficial]

+Victoire We try! Thanks for watching!

[@fayyoosh7870]

That’s how great and technical he is ! ❤️

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U gfc

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[@sonamhitendre8561]

This guy is legit the best lecturer ever! It all makes sense with you. Thanks so much!

[@shahabuddin6149]

Love you sir,,salute your hardworking,,you are amazing teacher of the globe,,I just pay fee to university not absorb a single words from university,,I am copying your every lecture and remember,,you are my ideal teacher,,God blessing you,,more than 100 students I spread your lectures and daily consouling,,abundle of thanks

[@johnaitidis4805]

God I hope my professors explained like this in their lectures. Your videos save my ass once again 😂

[@asyfaakhairani6929]

Best medical channel ever!! Sir, you really helps medstud like me ☺️🙏

[@amarachiobua9055]

You just have a way of making these topics easier and more understandable. Thank you so much sir. You're helping a lot of people☺

[@marylowman6040]

These videos are a lifesaver with distance learning. Thank you big time.

[@Ls-er3ts]

I would not be able to understand or pass my exams and studies without your videos. Thank you so much you are our hero.

[@dearestmedico7297]

this is the best embryology lecture I have ever seen. Sir, the lecture was too good with all the details of enzymes and differernt secretions.My concepts are crystal clear after watching your video. Thanks!

[@xBRx100]

my thanks to you, here from Brazil. you are an amazing teacher. Deserve all the thumbs up and monetization that is possible to have

[@jeniferbekee5705]

As a nursing student, i read wide and versatile like am a doctor (though is my wish).... You make it easier and gracious to learn more.... Thank you. 🎉

[@quratulainabbasi5512]

What a way of teaching ..you make me understand each and everything just simply without wasting time.. best way of teaching👍

[@bonsyboom4531]

this is the only channel that i actually waant to remind me to hit the like button at the end of the video

[@Dimma_aniemeka]

I just understood this concept in less than 30 mins. Take your flowers🌹🌺. I use to hear of Ninja Nerd before I became a medical student. I'm glad to learn from you sir.

[@oyamatoayei4497]

Im indonesian and there are other who admire your work, i personallu very much thankful for all of your video sir, i must say your effort is pretty much appreciated. And im planning to donate some of my work on your patreon

[@banglavet3138]

Sir, salute forever. Love you..... I'm a DVM student.. Again love from Bangladesh.. 😍😍😘😘😘😍😍😍😍😍😍

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This guy does wonders! He is so good at teaching and it's fun to watch! Got a really good grade bc of him.

[@sumayyanaderi5044]

Hello Sir first of all thank you so much, Allah bless you you make videos for free I am watching you from Kabul Afghanistan. you may do not know how helpful are your videos specially when you made all free for student like me who does not have money to pay for learning again thanks a lot we all pray for you and your team have long life and blessed and live all healthy and great

[@hemberry_]

I'm watching your videos alongside my lecture notes and it's ten Times more fun

[@apo6508]

You are my lifesaver. I couldnt understand anything from my professor. Love u from Thai Medical student ❤.

[@matterain]

so far the best vedio explaining fertilisation on a medical level i myself as a post-graduate appreciate your effort thanks alot

[@kironkaijoseph4205]

I lack to express my joy, you explanation is excellent you're the best ever

[@namu_love]

THE WAY HE DELIVERS THE POINTS! you cant be bored at all!

[@mithunraaguld6999]

I have not even completed my schooling but when I see those videos I feel like I am learning true Biology and you are 👍👍👍

[@hassanm.kadhim6980]

حرامات انتهى الفيديو و الله الواحد ميحس بالفيديو من كثر المتعة اليقدمها زاك thank you zach 😍! it was unbelievable explanation

[@suhaibshalan8393]

GOAT prolly the best teacher ive ever seen

[@sofiareis427]

Hey, I'm from Brazil. Your classes help me a lot, I'm in Nurse school.

[@zeelpatel6354]

From india.... i send you a lot of wishes man💐... you are a great professor.... i really appreciate your work

[@asiakhatoon954]

Can't thank you enough, thank you for making it available, you are a superhero a real med ninja 🤗🤗

[@kennethgeorge482]

Nursing student from Kenya am enjoying the lessons.keep it up

[@karanuchege1628]

wow you are the best teacher ever.....i enjoy your videos ,,,thanks a million

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When it comes to Ninja nerd lectures , my video quality increases to 720p ...❤️

[@chetnasingh9970]

U r like blessing for medical student like me u made all content very easy to understand ... It's my request plzz never stop making video ..... Loads of respect...

[@venkateshwarlus8015]

Superb class.This channel is very helpful for students who want to study in depth

[@cynashine4950]

I really admire you sir....u help me a lot going through med school...i really wanna see u in person one day...🙂

[@phinahB]

Wow! One would think it's world war in these bodies of ours. The number of events happening at the same time is insane. Thank you, this is well understood.

[@doni_sinha]

These lectures are really a huge box of gold to me !!!!! Really awesome thanku so much for such a beautiful , amazing explanation !!!!!!!

[@justthabi]

Hi Mr Ninja Nerd Sir, you really teach all of these concepts with so much passion. I am going to pass Anatomy & Physiology because of you.

[@faithd1982]

Helping me get through Anatomy classes one video at a time

[@dilipkumarsharma8651]

I haven't seen such a cool teacher!! It really help to understand quick and kind of grap most of the things.. Yo!! Sir!! Big salute... outstanding lecture.. ever boring topics seem interesting.. when you explain..

[@nicoleortiz2261]

Hey, I love your videos. They have helped me so much throughout my studies. You are honestly a god send

[@ahmadalkaabneh7475]

you deserve the 1k likes but you dont deserve the 7 dislikes, great job man i really appreciate the effort you put into the videos keep making these kinds of videos.

[@Mahi-fp5ct]

Bestest ever!!!! Why i didnt find you in my first year of med school!!!! 😍😍😍😍😍😍

[@mohammadhajjaj6556]

You're the best , and your videos are the best medical videos I've ever seen 💜💜💜💜💜💜💜💜

[@Matti85]

This helps me so much with my medical carrer, thank you so much, totally understand every topic i have watched on here 💗

[@dhritidas9882]

Another topic crystal clear. Kudos to you

[@gapitasarplah5542]

you are the smartest human I Know. You took my through Nursing School

[@mahekshaikh394]

Amazing amazing amazing!!! Great work.. Didn't find this indepth information anywhere on the internet.

[@Rawwr1ful]

The best explanation, so detailed but easy to follow. Thanks so much!

[@raghadmd5106]

perfect... I am an Arabic medical student..and your videos are very simple and useful..thank

[@balablubulaba-tf4pn]

Big thanks to you. From Afghanistan

[@balablubulaba-tf4pn]

❤

[@balablubulaba-tf4pn]

🎉

[@balablubulaba-tf4pn]

😢

[@balablubulaba-tf4pn]

❤

[@jocelynbuttress4651]

Trying to get a better understanding of how this process works, and you blew my mind!! So interesting, and fairly easy to follow and understand! Wow! And... Really easy on the eyes! 😉

[@charlesakhimienmhonan2175]

Thanks for the lecture. It is helping me a lot. The number of sperm that get to the fertilization site is actually about 200, but one usually fertilizes the oocyte.

[@victoriafarasat4267]

You are the best person on this planet

[@moscomillz212]

Your videos are all I watch ....I actually got a B from this lecture in my today exam thanks 🙏 ✅

[@catalinaimbernonvelez8560]

You save all our degrees thankyouuuuu

[@عقيلالعابدي-خ6م]

You are th smartest person in the world at all, love you dude, thank you for your affords

[@yasminhosam5951]

YOU ARE LITERALLY THE BEST. It all made sense and the whole explanation was very entertaining and fun to watch. Thank you so much

[@anjusinha8076]

Thank u bro...For clearing this whole concept in a very easy way...from India

[@kofipapa2886]

This is the first time I am commenting here. Zach, more power to your elbow. And I read that there's no fast-block to polyspermy in mammals. To the contrary it is found in marine invertebrates like sea urchins to ensure that sperms from other species in the water do not fertilize the wrong egg. But hey, I trust you and hope you will respond. I will be over excited to get your response.

[@wajidbashir2342]

Dear, you have a good way to elaborate the complex process of fertilization

[@urmellakumari7410]

your lectures are very very helpful to me😊. Thanks for making embryology easier 🌼

[@joykalenga-m21]

Honestly, thank you so much for your videos Sir. You are truly a blessing. Seriously thank you. You’re a lifesaver🥺. FromZambia 🇿🇲

[@networthassoc2006]

You my friend, have a natural gift/ talent. Keep up the great work.

[@katerinadimitrova-hristova8628]

Благодарим ви!

[@NinjaNerdOfficial]

You are welcome! We are glad you found it helpful! - TG

[@FosterChenga]

You explain and simplify things in a good way... I always understand

[@naveramukhtar1614]

One of the best teachers out there! Kudos

[@Happy-nc9zf]

Daamn bro wen the embryology lec taught this i never really thought fertilization was this mental damn mahn ... U r awesome

[@kaloyanmomchilov3539]

Dude I can't believe I'm just finding your channel. This is amazing

[@tintti6025]

I've read, and my lecturers also told this, that in humans practically the whole sperm cell enters the oocyte. Plasma membrane gets left behind but everything else goes in. I think paternal mitochondria get destroyed so only maternal ones are left, and the centrioles of the sperm cell are inherited by the zygote. There are so many misconceptions and alternative explanations going on about what parts of the sperm cell actually enter the oocyte, and right now I'm too busy panic-studying for my exams to really look into this. Just thought I'd give y'all something to think about and maybe do your own research if you're interested. I'm gonna go with the explanation my professors gave, and hopefully pass my exams :'D

[@nitigya_17]

Can't thank you enough.... you're literally the best ❤️

[@jannatunnahar4084]

Your lectures are very very very helpful Thank you sir❤ Love from Bangladesh

[@chiahsuantsauo8375]

Hi guys, I noticed there is no videos that summarize the physiologic changes that occur during pregnancy? Anyways I hope you Prof Zach can make a video on that. Thank you

[@منتظرعلي-س9و4ع]

YOU ARE THE TRUE HERO ✨✨✨✨

[@paddricnyanzi1942]

This guy just makes everything so easy

[@tattoogreenie]

Your videos are very helpful! I was trying to count how many times you say "actually" but I lost track at about 100. lol

[@elahehahmadizad8999]

tattoogreenie you must see our Histology professor !😕

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You are a real MVP!! I love you!! Don't stop what you're doing!

[@simisolaxo]

Thank you so much for these videos sir. You are literally the best!!

[@waqarnaqsh8275]

Outstanding, ❤❤❤ Respect & love from Pakistan.

[@brendabwalya3696]

Can you please consider making anatomy videos like these please?? You're the best at explaining

[@turningpoint7209]

Love from India 🇮🇳

[@alipasha7645]

Asslamo Alaikum SR,Your lactures are very Great very Helpfull and comprehensive! Your style of teaching is also very great!! Thumbs up for you struggle! Please make lecturers on complete embryology, and Monosaccharide Metabolism, xenobiotic metabolism,Feed fast cycle.

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I am a aspiring candidate for NEET 2025 and your videos really helped me ❤❤

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Respect & love from Indonesiaaa

[@jakecaiola217]

brother, you are special. please dont stop

[@esmmypinkstar]

Thank you so much! You cleared so much stuff for me! My professor let us go over this part on our own and the book was so confusing! 😁

[@EvanTheJust]

I have actually watched the actually first actual seconds of this actual video and I am actually astonished by its actuality. I am being completely actual.