you are the ADHDers dream professor. Thank you for starting by explaining the bigger picture.
@bobcocampo Жыл бұрын
Any update? Can Nitrostat help?
@stanilastoeva24946 жыл бұрын
Amazing presentation! You are the teacher I want to be someday! :) P.S> Cool interior! ;)
@notredox24 жыл бұрын
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@lalibeluladiaz6 жыл бұрын
So helpful!!! you made it so easy to understand and I have to say English isn't my mother language!!! Thank you
@7ryan38 жыл бұрын
very simple but nevertheless very informative you are a fantastic teacher keep up the good work
@PhysiologyforHippies7 жыл бұрын
Thank you!
@lobnaal-temimi24237 жыл бұрын
thank you so much ! from Denmark :) Your approach, voice and explanation methods are pleasant to listen to as well as fun. You are good at simplifying the subject.
@VoidHalo8 жыл бұрын
Interesting video. Interesting channel. Definitely subscribing. Thanks for posting this.
@rogermcturk56824 жыл бұрын
Hello I like your presentation, I was chasing the subject of Nitric Oxide and how it works after reading Dr Esselstyn,s book on reversing heart disease. In the book i got the impression the Nitric Oxide is on the surface of the endothelium this then stops the blood sticking to the surface of the endothelium. You mentioned also about the oxide being released relaxing the muscle to expand the artery and reduce blood pressure. Dr Esselstyn is also in favour of a whole food plant based eating plan to aid this process and mentions it can ease angina, have you read any of his books? I am not promoting his work more i am very interested in this topic, many thanks
@tommyssanderson Жыл бұрын
Hey ROger. -how did the interest go with Dr Esselstyn research & reading? His work is excellent ;-)
@jamesalles1393 ай бұрын
whatabout the vascular endothelial glycocalyx? A shield from direct contact.
@jameswilson92392 жыл бұрын
Nitric oxide should not be confused with nitrogen dioxide (NO2), a brown gas and major air pollutant, nor with nitrous oxide (N2O), an anesthetic.[7] Lol, NOS.... your funny. Nitrous oxide (N.O.S) is not nitric oxide (N.O) Nitric oxide and nitrous oxide are such two compounds. The main difference between nitric oxide and nitrous oxide is that the nitrogen of nitric oxide has the oxidation state +2 whereas the oxidation state of nitrogen in nitrous oxide is +1
@franklincornelius9373 Жыл бұрын
Good info, I like how you just get into the discussion without all the meaningless jabber. We look at a lot videos and most are long with unnecessary stuff, whereas you are short, direct and to the point. Thanks
@victoriaferro85917 ай бұрын
I loved the explanation, thank you very much. Could you make some content about exercise and nitric oxide?
@religypoggs28228 жыл бұрын
Thanks for this video!! I really love your presentation and found it very helpful in understanding my lecture!
@PhysiologyforHippies7 жыл бұрын
You are very welcome.
@hero-gl4zy2 жыл бұрын
I hear That penis pump indeced in the beganning alote of NO so it give some good sensation in the beganning. But due to over negative presure it increase tgf beta indecate inflammation response. In this point is it make the peins numb with lower erection quality. In this point What happen to endothelial linning in the cavensal carpora?
@BecauseWeAreIAm9 жыл бұрын
She is fabulous!!
@kcamillefreeman8 жыл бұрын
+Eating For Acne Thanks :)
@PhysiologyforHippies7 жыл бұрын
Aw. Thank you :)
@catalinharrison75756 жыл бұрын
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@DocAmikable Жыл бұрын
Love you 💯 But still very much interested in the I-NOS & N-NOS effect
@stevem81282 жыл бұрын
You are so sweet and smart I am out of words, WOW bravo !! So blessed by the Almighty God Jesus Christ to have found your video and channel. Thank you for a straight forwad, with pictures I might add video easy to follow and understand. Looking forward to the next👏
@joycemtc9 жыл бұрын
you explained everything very clear !! wish you can upload more videos on the biochemical pathway :)
@Sun-is4bl10 жыл бұрын
thank you! this was super easy to understand although I think it would be worth it to go through the biochemical pathway
@ameenullah35843 жыл бұрын
Plz tell the source maam
@ameenullah35843 жыл бұрын
Source name plzz maan
@H4SAH47 жыл бұрын
This was very helpful! Thank you! Keep up the good work :)
@codonoghue55918 жыл бұрын
Such a fantastic presentation ...I could listen all day. Plus the way you teach the material, it stays in my memory. Thanks a million. Corla.
@kcamillefreeman8 жыл бұрын
+Comhairle O Donnchadha Thank you!
@PhysiologyforHippies7 жыл бұрын
You are welcome!
@nataliehell50239 жыл бұрын
hi, i love the way you explane! can you give me more info on eNOS?
@jameswoodall92613 жыл бұрын
The Hippie thing got me. Content was fine also.
@emilyyy71310 жыл бұрын
Great video, looking forward to more. But I wish you went into a little more detail about the reaction at 5:00. Just a suggestion for future videos :) Thanks!!
@kcamillefreeman10 жыл бұрын
Thanks for the feedback! I was worried that it was getting too long - perhaps in another video :).
@RyanF08009 жыл бұрын
more details on reactions are definitely needed ( as a uni student thats whee the top marks come from) then again description does say basic overview so thank you for clearing up a lot of factors that confused me!!
@kcamillefreeman8 жыл бұрын
+RyanF0800 Will try to get to a more detailed description later. Agreed - those details are important.
@ruffyatutube2 жыл бұрын
I'll bet endotheleum can also stimulate smooth muscle above it to contract that vessel, not just dilate it. During contraction, stickiness or "hold until help arrives" can happen when an underlying toxin is detected by endothelium.
@praveenkumarkhosla94263 жыл бұрын
Excellent beautiful, India
@belindaputriagustia20743 жыл бұрын
thank you for your presentatiot. it's wonderful. i just want to make sure. so, NO has a bad effect for vessel right? meanwhile it can make vasodilate vessel, but it is also make stickiness
@evandermcmillan97267 жыл бұрын
Hi there.I took proargi 9+ and that pm bp was105/65 shrtly after.But next am bp was 193/101.I think I have a problem with the grape seed extract.Got any thoughts.
@JK-qf6qq4 жыл бұрын
Hey, if youre still checking the comments- I do worry about the processes you skipped (eNOS and cGMP effect) and would very much enjoy an additional video! Thanks for the overview :)
@sfgox106 жыл бұрын
Can someone please tell me why chronic weight lifting doesn't damage endothelial cell function due to shear stress? Obviously the paracrine function of NOS in the cell would help, but if you lift weights 4 -5 days a week for 30 years of your life, and go intensely, you'd think that it would damage the cell lining? Any evidence based research on this?
@Rene-uz3eb2 жыл бұрын
So interestingly, the shear stress sensors are cilia using polycystin 1, which as the name suggests is heavy in sulfur. So if sulfur was deficient, you'd expect problems here, especially as ciliary turnover is quite high I recall
@ZippyCoheny7 жыл бұрын
Great video, my daughter has pulmonary hypertension from Pactus Ductus Arteriosis. Thanks for the video. Informative.
@rechargebatteries10454 жыл бұрын
cGMP causes the dephosphorylation of myosin which decreases binding to actin = smooth muscle relaxation
@tommyssanderson Жыл бұрын
This is a great video. -super cool explainer - thank you so much!!
@TamalRoy503 жыл бұрын
Very nice explanation! My question is: do the endothelial cells change their shape during the vasodilation? i.e. does the allignment of the ECs change from along-the-blood-flow to perpendicular to the blood flow during vasodilation? I would imagine having a constant number of deformable cells on the endothelium, that is the case.
@jonahbert1113 жыл бұрын
Rats, I'm not a hippie
@pradeepbalachandran9224 жыл бұрын
is it good for pad disease in legs and calcification in the artery such as arteriosclerosis
@paintinggal13 жыл бұрын
how you teach makes it fun and exciting to learn
@firojmulani74956 ай бұрын
Very clear
@lucilaalvarez50345 жыл бұрын
Thank u so much this was very helpful! 🙏🙏🙏
@MubashraZahoor2 жыл бұрын
❤️❤️
@plamgogbg10 жыл бұрын
Fantastic!
@kcamillefreeman10 жыл бұрын
Glad you enjoyed it.
@bcvthompson8 жыл бұрын
Fab! Love it! Thanks so much for this. :-)
@racheid778 жыл бұрын
awesome video, thanks so much.
@haughem8 жыл бұрын
Hi you mention another video which follows on from this one (covering glycocalyx) - I can't seem to find it on your channel. Is the video still live? thanks :)
@kcamillefreeman8 жыл бұрын
+haughem Hi! I haven't actually found the time to make the glycocalyx video yet. This was a great nudge, though. I'll try to get to it this week or next :).
@arshithgowda87282 жыл бұрын
@@kcamillefreeman looking for your glycocalyx video
@carrollhoagland10537 жыл бұрын
Tx, good job ... 70 Going On 100
@Fun-hb8pg7 жыл бұрын
where is next video? T_T
@MfAvengersPlay7 жыл бұрын
Excellent work!
@rachelchou99918 жыл бұрын
It helped alot thankyou!!
@hayatullahmohamedislam48766 жыл бұрын
outstanding thank you
@mitchellmulcahy99765 жыл бұрын
thank you
@user-ve9xl9uo2c7 жыл бұрын
Thanks
@hondaguy597 жыл бұрын
Good information but her arms waving around during her presentation reminded me of an unattended fire hose.
@PhysiologyforHippies7 жыл бұрын
Hi, Evan. Congratulations! You have won an award for being a jerk on the internet. I absolutely love to hear comments on my videos - which I make on my own time for the sole purpose of helping people - that serve no purpose other than to make me feel bad and/or to make the commenter feel superior. Have a great day, and enjoy your award!