Nobels 2016: How Your Cells Stave Off Starvation

[@ayushvora2346]

Fun to see her getting better as a host.. She took everyone's"expressiveness" comments seriously..Though it's like we're all hyper-hormonal teenagers welcoming the new girl in class.. Give her a break plz

[@SafetySheepRnD]

Yea, she really cleaned up her vocal fry over the course of 2-3 videos which is pretty impressive since that's typically a habitual thing. Kudos to her. I think she'll do just fine on this channel.

[@Capkauna]

i feel like her voice too high at times, even with my phone on medium volume i still need to muffle it so i don't get the spikes. then again, i might be more sensitive to this kind of voice than others, dunno... other than that, sure. i don't really care much ab how she looks or how she moves as long as the info is accurate and well presented.

[@LiftOffLife]

This girls voice is grating. Get a man on presenting you feminist supporters.

[@mfaizsyahmi]

The Nobel Prize Committee literally took MY WHOLE LIFETIME to give him the prize!

[@StormyBro]

Olivia did a wonderful job with this video

[@Tazallax]

Her voice is so relaxing

[@halem6580]

+

[@gracegrass4462]

+

[@TDghf]

she needs to slow down for the idiots like me who cant keep up.

[@jonahbrame7874]

might I recommend changing the speed of the video? click on the settings in the video, go to speed and pick a speed slower than 1

[@hakachukai]

You should put a polarized filter over the camera lens so that it will block the reflected light from your glasses.

[@naota3k]

That's a lot of work to fix something almost no one cares about or notices.

[@hakachukai]

It's not a lot of work at all... and trust me, EVRYONE notices!

[@fireglory23]

Uumm, not me

[@kraakenhex8459]

You're not Hank.

[@robspiess]

You're not Ron...

[@karlsson8439]

you're not Hank too.

[@miloradvlaovic]

Karlsson *you're not Hank either

[@gold22silver]

You're not Patrick

[@SapphireX413]

Is this the Krusty Krab? NO, THIS IS PATRICK

[@ChuckFreeburg]

Best KZbin summary of this. I’m not even done watching but learned so much more. Thanks for posting.

[@phantasm1234]

Can you do one on cerebral aneurysms? I had one rupture at 19 and would love to learn more!

[@sacr3]

Doesn't take much to google it.. I don't think its worth an episode to explain what an Aneurysm is - fairly straight forward, weakened wall gives out, could sit there for life or burst from further weakening.. done

[@JoseGranny]

That would be interesting.

Why not spam? Spamming questions seems to eventually get them answered. At least the question is more interesting than someone's hirsute anus.

[@meinbuch9458]

+Sheldon Robertson Those anus jokes are indeed annoying.You raised a good point though,if Scishow made a video on the cerebral thing then i would've learned more about the human brain,i shall delete my comment.

[@vanrozay8871]

Another interpretation of test results: While teens' brains were more plastic and adept, their remembering the peripheral objects, especially when they answered wrong, suggests they were more easily distracted than the older participants.

[@xxSome3Girlxx]

I missed Olivia. Her voice is so soothing

[@FabledThunder]

I kinda like Olivia.

[@CharlesTheClumsy]

Cri if you liek evrytiem

[@lvennard]

i'll admit, i down voted her at first, i think the nose ring distracted me. but she has made it to the neutral area now, and i am more paying attention to the content of the video.

[@oughtism2798]

I still think she talks a bit slow for educating, but YT has a fix for that and shes a QT so I don't mind.

[@magicbuskey]

ThunderGun2 I like her too. The jewelry under her nose looks like a sparkling booger and is distracting. No offense.

[@healthystrongmuslim]

fuck you, magicbuskey. no offence, magicbuskey.

[@Rhyff]

A professor at my university got the nobel prize for chemistry, so proud :)

[@maaikekaynta5079]

Astvtic groninguuuuuun

[@maithao7805]

_wow _seriously? _congratulation ^^

[@samnassar6182]

Astvtic so you go to utd??

[@danthadon87]

What’s there to be proud of? It wasn’t your achievement.

[@jimbultas]

Another great SciShow episode. Thank you for you're consistent quality. This a plead directed at the editing style. I strongly dislike the super tight cuts that remove any pauses for breaths or at the end of sentences and often start just before the previous one ends. It sticks out to me every time and distracts me from what is being said. I realize I may be a small minority of people who notice that and you can't please everyone. Either way, keep on keepin' on and thanks!

[@Tati11233]

She's improved tremendously in a short amount of time. Good for her.

[@tallatech]

KZbin Comments: The True Meaning Of The Death Of Originality.

[@Kurokodairua]

I just watched the first video she was in. I want more bug stuff.

[@chowtom5174]

Kurokodairua it's bugging you isn't it

[@Kurokodairua]

Chow Tom yeah

[@GuilhermeSilva-uq7on]

i think she's doing great as a scishow host. Keep up the good work guys and gals!

[@Quokkat7]

love this girl, great video

[@crapstirrer]

The best Olivia episode yet

[@patriciaborron269]

I enjoy Olivia's presentations. She gives the information clearly and I like her enthusiasm. Of course, I'm a nerd, but I'm damned proud of that.

[@halem6580]

+

[@jonahbrame7874]

+

[@YBlvr]

Why are people so hung up over what Olivia's wearing??? This is an educational video, not a fashion show.

[@the1exnay]

VL (YBlvr) hating on her appearance has become a meme, so too one could argue is being surprised by the hate

[@dandylionsloth446]

because she is woman talking about science

[@nekotato4581]

I think it's cute tbh, I have a shirt like that....

[@Kube_Dog]

She's a poser. Wearing the uniform she's expected to wear for this role. Poser.

[@CyberNinjaZ44]

You're a great host, keep being awesome!

[@pabloalfaro3768]

Keep your work guys ! You have been doing really well ! I would really like to see more videos about nobel's scientist or just make a little serie about the Nobels :)

[@brisfocus3648]

Olivia is smarter than the sum of all the comments here

[@InvokingPeace]

that's not a big feat... just look at the comments

[@ParleLeVu]

Oh shut up.

[@herilianeria3735]

Bris Focus i have bigger boobs

[@arthurhoseok1028]

Ricardo Neria no one cares

[@danthadon87]

Comments don’t have intelligence. She’s simply a higher achiever than the commentators.

[@lefurrling]

I love Olivia. She's the ultimate nerd girl.

[@VR_Wizard]

Happy science christmas everyone.

[@kiwicolonel6864]

Hey, why are Olivia's glasses still so reflective? I thought she got new ones?

[@Masterpouya]

According the fact that they probably record many episodes at one time, new glasses are gonna be used soon!

[@ssss0094]

I can't believe that no one still haven't won the Nobel prize for discovering CRISPR Cas9 that led to developing genome editing....

[@Masterpouya]

« Time » is the answer, they will eventually get it but not yet cause it's not an « old enough discovery ».

[@bobjones4469]

How long has it been? This guy got his prize 20 years after he published his findings. Guess they have to wait and watch the influence and significance of the discovery first, not to mention that there are probably a lot of other discoveries to access.

[@Master_Therion]

That's interesting that they are figuring out the teenage brain. I hope that someday science will give me a method for keeping those damn teenagers off my lawn! - grumpy old man.

[@daedra40]

Awesome video, and awesome new sponsor.

[@eduAC.]

Great info. I'm waiting for the physics related videos, too. Glad to see more of this host as well!

[@uiomancannot7931]

I like all the hosts...

[@michelenakamura3360]

Finally, someone who has explained this process better than my husband.

[@AHunDread]

The way you wiggle your arms about almost makes you seem like you're doing the robot. Just something to giggle about!

[@michaeldavis6607]

I have hearing loss and usually have to turn the volume to max for most videos. I had to turn it almost completely down for this speaker.

[@theswedishchicken5963]

Great video! I really like this host

[@nerdknowledge2056]

Great job Nobel Prize winners!

[@ozdergekko]

You're such a fast learner. Striatum and Hippocampus still co-operating well ;-)

[@ajaaniajaa]

Can you please do a video on why do we itch?

[@the_feisty_yeti_4101]

that would be interesting, i've always wondered about that.

[@joeyno137]

damn I read about itch in my biopsych book and I'm to lazy to look it up now. as for now, to get rid ( ignore ) of an itch is by pain. scratching it will stimulate the pain receptors which overrides the sensation of the itch.

[@maylien]

Science Christmas, Yay!

[@Kavriel]

I like Olivia, she's doing a great job. What i don't like however, is her glasses, and especially the reflection which is a bit distracting. But i'm nitpicking.

[@Masterpouya]

SciShow team said in the comments of the previous video that she bought new ones with anti-reflecting coating and that she's getting them soon.

[@Kavriel]

Masterpouya Oh really ? Cool !

[@jamieohjamie]

She'd probably look better in contacts. Very few people look good in huge frames and I don't think she's one of them.

[@rofared87]

Down to the lighting folks though, isn't it?

[@Correctrix]

No, it's not down to the lighting engineers. She got cheap glasses without an anti-glare coating. Since she's a host, she should probably invest in a better pair.

[@Kirbynessness]

Uh, no, it's the Science Grammys. lol

[@janedoe9316]

First off I would like to commend Olivia Gordon on her insightful lesson on the 2016 Nobel Prize recipient, Yoshinori Ohsumi. I know that I, personally, was looking to find out more about his work and Gordon did a great job introducing his work and uncovering some of the more intense science behind it all. The Nobel Prize in Physiology or Medicine was earned by Oshumi for his work in cell biology, more specifically autophagy. “During autophagy, a cell transports its broken-down components to a certain area where they’re taken apart, so that their chemical compounds can be reused.” Gordon then goes on to say that Oshumi used this process to backtrack and find out how the science of it all comes together, he identifies the fifteen genes that are crucial for autophagy. I was curious to know what those genes were so I did a little extra research on the topic. I was unable to find the specific genes, but if anyone is able to find them, please respond to me or send me a message containing the information, thank you. On to the next portion of the video, physiology of the teenage brain, was insight to how the teenage brain reacts to rewards, and compares the teenage and adult brain. In the experiment of playing the game it showed just how well teenagers reacted to positive and negative reinforcement. The striatum is the portion of the brain that is known to handle the process of reinforcement, which brings us to the conclusion that when you are a teenager your stream places a larger role in the brain, and lessens when you get older. The teenagers also used the portion of their brain called the hippocampus, which is where the brain handles certain memories. Only the teenagers were able to use the striatum and the hippocampus in combination to help themselves out in reacting. So therefore it is scientifically proven that teens are more likely to learn from their actions when shown positive or negative reinforcement.

[@tamatoashort457]

I'd like to see him explain his own findings about autophagy so that nothing is distorted.

[@infrabread]

The prize for chemistry was given to one of my sister's lecturers...

[@Ptericles]

Does autophagy only happen in extreme calorie restricted diets (near starvation) or can autophagy can happen on a smaller scale during intermittent fasting?

[@bin1127]

OH Hello, never seen you before. Great work on this video!

[@mrpants345]

Olivia is a great host!! Sci show is home to the best hosts in the fuckin game. wow sci show nice moves keep it up proud of you

[@marcr3568]

Question: (Like To Get Seen) what's the deal with rubber pencil phenomenon?

[@ShopTalks]

He wrote this paper in 1993? why did it take 23 years to award this guy a prize?

[@kill100578]

Because the Nobel committee often take time to judge the long term impact of the work and the other avenues of research it leads too

[@piranha031091]

It's science, not journalism. It takes time to be sure whether a paper's conclusions were correct, and to see its true impact on the whole field.

[@VR_Wizard]

+Bertie Wooles This Theorie is nice but only applies to the science prizes. If you look at the Nobel Peace Price you notice Obama got it I still don't know why and now the Colombian president got it. I think they use the price to shape the future by encouraging good behavior immediately to make its impact greater.

[@HBSKATE]

The nobel science committee not the fucking peace prize

[@VR_Wizard]

HB SKATE I know and I agree with the statements made here. I just want to point out that they do it differently with the peace prize and why I think they do so. No hate I like to skate too. :D

[@tarkusd7534]

so... can i reuse my poop too if i hold it long enough while not eating?

[@flatplant]

I don't think many people complained oivia was a bad host, previously it was just the way she dressed in contrast to the other hosts, it just didn't seem too professional, I think she's fine.

[@Endymion766]

So does autophagy help or hurt diabetes and cancer, or do we not know yet?

[@akshitbonkra4934]

I sub'ed to this channel when it had just 200k subs! Im feeling old now!

[@OutputzBeatz]

Have you guys got a link to the paper about the "Teenage Brain"?

[@zachcrawford5]

Wow i've never heard someone butcher the pronunciation of "autophagy" quite like that before.

[@clarencechoo5104]

That's how you're supposed to say autophagy. Look it up.

[@zachcrawford5]

Clarence Choo Perhaps I should listen it up, might be more effective lol.

[@clarencechoo5104]

Close enough *shrug*

[@CarlosTorres-vb5mb]

your first episode discouraged me a bit, because it wasn't very good, and you looked very nervous. However, I think your getting the hang of it, and good job on this episode.

[@mithril1991]

FFS the channel's primordial purpose is informative. Comments about idiosyncrasies of the hoster are irrelevant. This just shows how obtusive and superficial some of you are. Grow up.

[@Zeldaschampion]

I wonder what happens to the sponsors with vulgar names.

[@AlbertaGeek]

Unfortunately, too many teens have been wasting that superior learning power ever since video games became inexpensive and common. Also, they won't stay off my lawn.

[@jaquelineberge217]

I really mean this as a constructive feedback: you guys should really prepare her more for the videos. She should spend some time watching herself going through the script in front of the mirror or after a recording. She used to be monotone, but I guess since the amount of critics she got, she is now trying harder to give her speech a different entonation. The problem is: it got unnatural, like she is trying too hard (A for effort!) Also seems like she doesn't know what to do with her hands or how to gesticulate, hence again why is it so important to watch herself and rehearse more the script. She has gotten better, but she is far off of becoming someone with such good oral prowess as Hank or Michael. It feels like she is an introvert with high levels of anxiety being forced to publicly speak. :( I just feel sorry for her if that is nearly the case. But I guess that if she signed up for the job... she must do it... Maybe theatre classes will help. oh and please, the reflective glasses are so distracting!!

[@alexjordan8838]

Jaqueline Gimenes I agree with you on this. She is getting SO MUCH BETTER but she still has a bit to go. And your comment is not rude or hurtful do thanks for that

[@Masterpouya]

About the glasses: From previous Olivia's video, SciShow team said « What a well-timed question--Olivia is getting non reflective glasses today! » According the fact that they probably record many episodes at one time, new glasses are gonna be used soon!

[@RetroSkreamerz101]

Just a personal theory but maybe the striatum & hippocampus were active in teens bc they use that part of they're brain more. Teens that are school often have to retain more things to recall them later for exams and the like while some jobs may not require that of adults or may not require it as often. This could lead to weakened connections between the striatum and hippocampus so my question: what was the age group of the adult participants in these studies and how long have they been out of a school setting?

[@alexclark9923]

How and why does the wind whistle?

[@lotso133]

I might be wrong but wouldn't the autophagy processes related to a potential solution with protein build up in Alzheimer's disease or other Neuro-degenerative ones ? I mean it's bascially a disturbance in the balance production/decomposition of protein which can't be stopped. Thoughts ?

[@xxxxfatcatxxxx]

So the cells recycle their own waste? I wish humans would act more like the cells they're made out of.

[@MrTheWaterbear]

Eat shit? Great idea!

[@tron-8140]

Don't worry one day we will get it right. Have faith!

[@sad_depressed_weeb4996]

*Moomm Hank wearing Olivia's skin suit again*.

[@Karma8Kami]

Hm... just had an idea concerning piercings after watching Olivia. A lot of people like em, a lot dont, so why not give them practical functions so as to make it more reasonable for everyone. Piercings like that could be used for securing bluetooth headsets and different types of earbuds better for people that are working out, people in construction and other physical labour etc. As for the nose ring I am not quite that clear on what you could use it for to be honest, diabetics and people with health problems might attatch a small sensor that measures their outbreath for different chemicals, thus allowing for health monitors connected to a smart phone. You could have a screw on point for odorizers for people working in or around sewers, nursing homes and the likes where you run across bad odours. I am wondering if you couldn't even make a reasonably small microphone to hang from a nose ring, thus allowing for minimal bumping and that kind of intererence while having it close enough to the mouth to allow for a much weaker receiver than norma, granted you'd need a wind shield for the backside. I donno, makes sense to me if people would find a use for the damn things, maybe it's just me though.

[@sostikathapa7101]

We can drink water or not during fasting?

[@zerorebellion4084]

So basically teenage life is the best time to learn. I should've known it when I was 10 years old so that I've spent my teenage life studying.

[@witeken]

Who is she?

[@stardreamer8996]

Read the description Olivia Gordon

[@JeanPaulHigley]

Can you do something about the lighting please? I find the reflection in Oliva's glasses a bit distracting. Thanks! 😁

[@JeanPaulHigley]

in future videos I mean. 😉

[@Pyke64]

Why do we always use Greek words in science and medicine ?

[@quetzalthegamer]

Makes it easier for professionals to communicate. And it's more efficient to boil down a complicated idea/process down to a word or phrase.

[@notadev1590]

We also like to pay tribute when naming things. In some cases that's a matter of using a foreign word or someone's name as a basis for our word. The ancient Greeks were pioneers in science and medicine.

[@quetzalthegamer]

***** Not a "form" of Greek, necessarily, but partially composed of Greek. Greek, Latin, French, and (Anglo-Saxon) Germanic are the main languages English is derived from.

[@edi9892]

1) For science new words need to be developed 2) and using ancient Greek or Latin, no modern language gets a special treatment. 3) They were the pioneers, thus it's more an expansion than something completely artificial 4) you can see it also as a tribute to the geniuses of the days of yore.

[@Pyke64]

Thanks for the answers, everyone :)

[@MindLaboratory]

so you're saying... the kids are alright

[@dfjshjkd]

nice im slowly losing my ability to learn as efficiently

[@jaimejose1317]

Is it safe to touch Liquid Gallium?

[@zachyoung6537]

Why do I get the feeling that this woman legitimately uses the word "triggered"?

[@culwin]

You seem legitimately triggered.

[@krisanthonysilveira8244]

its basically science christmas !!! :P

[@Ty6260]

Does anyone else hear this like high-pitched grating noise accompanying the video? I cant keep the volume up high cuz it hurts my ears. And no, I do not mean Olivia. Every time the audio dips or climbs my ears are like ooowee

[@tron-8140]

Maybe you have super hearing and can hear sounds other people cant :O or maybe your computers sound card isnt grounded properly...either way it sounds fine on my end.

[@k0r0z1f]

How far are we from simulating the universe?

[@myrdale]

How far are we from stimulating my anus?

[@k0r0z1f]

Benjamin Mosley lol, I hope the clowns get ya

[@alveolate]

does her intonation sound like she's asking questions every sentence?

[@AEther0238]

I thought they meant Cellphones.

[@TaylorPeterson913]

Why is it called au-tof-a-gie and not "auto"-"phagy". The second pronouncement makes more sense to me. You know, like the two Greek words for self and eat?

[@karlsson8439]

being a regular reader of Toriko, I already knew all about autophagy ;)

[@Kavriel]

Legit source of knowledge there.

[@karlsson8439]

well, me saying i know all about autophagy from reading a fantasy manga is kinda like saying I'm a great business man and lose a billion dollars in a single year. #maketorikogreatagain

[@Kavriel]

Karlsson We're going to cook god, it's going to be great, believe me. All the food spirits will tell you, I'm terrific at cooking. The best, even. And do you know why ? That's cause i've more food luck that anybody else. More than anyone else, let me tell you. And then we're going to deport neo, because he's a murderer ... some say he does drug, and i've heard people say maybe it's because he's weak, i don't know but some people say that. We're going to deport him and we'll make him pay for it. Terrific, great, best, believe me *error in asshole simulation* Shutting down ...

[@ATamedBuffalo]

Kavriel uhhh... Hmm... Interesting

[@celinak5062]

+Kavriel that impression was almost to good, you know now I do wonder how he would sound as a demo, lib, green and?... central.

[@henrikmogensen3305]

Shishow can you explain the phenomenon known as "Marie Antoinette Syndrome", which can turn your hair White/silver. It is said to be caused by a lot of stress but can you explain it? :)

[@TrishCausey]

It really is okay to have a beat between sentences. You don't have to edit the sentences so close together. And the speaker needs to learn how to alter her voice pitch so that it's easier on the ear.

[@ELYESSS]

do more stuff about bugs please

[@loganstone8205]

ah-tah-fuh-gee. I prefer auto-fayjee.

[@FootysMaXeD]

I agree, her pronunciation of the word was a little odd sounding.

[@Minty1337]

huh, sounds right to me

[@EdwardDowner]

Especially considering the roots of the word. Auto - self and phagy - eat. That "eat part is also in words like phage, phagocytes. Though that last one throws a wrench in the pronunciation.

[@FootysMaXeD]

Ya, auto like automobile. and phagy like phagocytes. The way she said it sounded just weird.

[@Correctrix]

It's neither. It's /ɔ:'tɒfəd͡ʒi/

[@louisjoseph5368]

What is oldest language in the world?

[@allnewluke1]

Oliva takes forever to talk

[@Jake-kn3xg]

Is Olivia from NYC I bet she is. Tell her I said "Hi".

[@PSPMHaestros]

She's so cute

[@bonniedean9495]

I love that new girl, what is your name?

[@Kurokodairua]

Olivia

[@dbartholemewfox]

My name is Dan. Not sure why you're asking... But Olivia is great!

[@1337watchtower]

READ THE DESCRIPTION

[@marj736]

Agent Colon Rectum

[@equitime77]

Can someone teach how to do different gestures with her hands. I know it seems trivial but it is distracting me from something I wanted to watch

[@ashleyhel]

The teen stuff is fascinating and absolute vital info for educating and parenting. Good to apply to my kid in like 3 years. ahh.

[@walterhartman3636]

I would like to know why some people talk with their hands and others don't.

[@huldu]

The older you get the less you care what other people think.

[@Z325i]

I like your glasses but the position of the lights needs to be changed because it is distracting.

[@Stue-e]

if you are reading, this scroll up and remove your mousewheel, whatever you are looking for it isn't in these comments.

[@CrazyNerdMonkey]

Does that mean starvation is cannibalism

[@1337watchtower]

Saying "Your cells" implies that I am something other than those cells, like a ghost or spirit. The cells are not truly me, I just own them. I label this video dualism propaganda!

[@AnonyMous-pb6nj]

Ayyy physics is coming next go Dawgs