Novel and Emerging Treatments for Schizophrenia Presented by Dr. Christoph Corral

[@noreenquinn3844]

A relative ( in her late 80s) in a nursing home with muscle weakness, loss of speech ( for a few years) and poor swallowing was given an anticholinergic medicine to reduce secretions ( a more recent condition). A side effect of this was she was able to speak again! Magic! Unfortunately after a short while on the anticholinergic medicine her speech got very fast and she got agitated so the medicine was stopped. Perhaps a slow releas form would have been better or a different route of administration?This wasn't looked into. This relative unfortunately died a few months later. Her return of speech wasn't looked into carefully enough we felt. This is often the case unfortunately in a busy nursing home whose focus is not research. Anyway this information may be of use to you in your research. The anticholinergic seemed to waken up the brain, then speed it up too much.. Sharing information across fields of medicine is so important.

[@Lipolimtown]

If you have suffer from mostly negative symptoms ipseity disturbance no thoughts in head and thought disorder (schizotypy) or only anhedonia and all it’s symptoms, not even aware of any positive symptoms would something like Ulotaront work?

[@constantinhaller4391]

Would have yes … sadly this medication failed

[@Roberto11231]

@@constantinhaller4391 They are doing more phase 3 trials for schizophrenia. I believe it will be approved. But it will take a couple more years to hit the market.

[@barbaramartinetti]

I keep hearing references to acetycholine and cholinesterase. I take mestinon for myasthenia gravis, which keeps the synapse point active. I took it during my pregnancy and my son now has schizophrenia. Is there any connection, or would mestinon help or hinder schiz symptoms. I'm a non'doctor.

[@noreenquinn3844]

if alcohol ameliorates schizophrenia symptoms (before it intoxicates and makes condition worse), should researchers look at what receptors alcohol affects? Fish oils in the correct ratio can do similarly from what I know? Also suggest, looking at processing speed generally in the population, as too slow or too fast may predispose a person to psychosis. Slow processing speed seems to facilitate system overload in the brain and the left brain? kicks in semi uninhibited and invents a reality while the system is in overload. People with slow processing speed perhaps need to be identified and taught how to live differently / take precautions in order not to overload the system?

[@noreenquinn3844]

Please also note, by system overload, I mean sensory and / or lack of sleep, stress, or bullying etc..

[@nemo3874]

alcohol mostly binding on GABA receptors and we already have a lot medications (benzos) with similar effect. But the issue that similar to alcohol you can get addiction to benzos, you can get tolerance to benzos and terrible withdrawal effects from benzos

[@c.k.1530]

Treat with anti parasites They have parasites Longterm treatment but they heal I realized it was parasites because her episodes had a schedule One year later family member almost back to normal

[@natalia400]

Can you please tell us how you treated the parasites?