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On the occasion of MIT Prof. Manolis Kellis receiving the Argo Award by the President of the Hellenic Republic, the National Technical University of Athens (NTUA, or Metsobio Polytechnio, often referred to as the MIT of Greece) invited Manolis for a short lecture and fireside chat on AI, Genomic Medicine, and Innovation, hosted by Prof. Leonidas Alexopoulos and Vassilis Papakonstantinou
Outline:
0:00 Introduction by Vassilis Papakonstantinou
2:00 Manolis Kellis - talk overview
5:10 Disease Genetics and Causality
13:45 FTO: Uncovering and Reversing the Circuitry of Obesity
22:33 Alzheimer's, ApoE4, Cholesterol, Cancer, and Immunotherapy
26:46 Single-cell Dissection of Disease Circuitry
36:02 Therapeutics: CRISPR, AI for Molecule Design
39:20 Call to Action: Pharma and Personalized Medicine
40:44 AI for Innovation, Discovery, and Idea Navigation
43:00 Q&A
52:10 Fireside Discussion with Leonidas Alexopoulos
1:29:35 Open Discussion