**OSMOSIS JONES**: a guide on what NOT to do in this ~panorama~

I was trying a different mic position, and it made the audio quality sound yuck :/ so I apologize for that 😔
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Copyright Disclaimer under Section 107 of the copyright act 1976, allowance is made for fair use for purposes such as criticism, comment, news reporting, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favour of fair use.

[@patrice1016]

when I was a child I imagined them fighting inside my body every time I was sick lmao

[@nunyabusiness1471]

Same!

[@KDsage123]

Same.

[@charliebrown3001]

I still imagine them fighting in me lol 😂

[@koatam]

Your immune systems were lame. Mine was robots fighting aliens.

[@hillarityTV]

I STILL do that 😅

[@shootingstarmolly]

*"Big Daddy Thrax is gonna let you have it."* This better not awaken anything in me...

[@marshmallow927]

I didn't realize how erotic that sounded until I watch the video-

[@Artsy2000Pink]

I can't- XDDDDD That sounds so kinky

[@osmanyousif7849]

"Oh yeah.... Choke me daddy..."

[@TheNitpickChick]

Is it weird that I had a small crush on Thrax when I first saw this as a kid? 😅 Like sure he’s an evil virus, and the movie itself did make me a lot more paranoid about germs, but I mean…. That voice and that character design though… 😳

[@shootingstarmolly]

@@TheNitpickChick Nah it's not weird at all, I myself had a crush on him when I was little. He reminds me a lot of Greed from FMA. What can I say? I love villains ❤️

[@arthurwatson2555]

When your subconscious is so bad, it even makes deadly viruses uncomfortable

[@matthewkalasky2891]

"This cat was sick before I even got here."

[@victorconway444]

In terms of biology, the one thing I found weird was the scene where Thrax manually raised the body temperature. It's not the disease itself that causes fevers. The body raises its own temperature in _response_ to diseases, since temperatures ranging from 100° F or higher are less hospitable to them.

[@LostButBroken]

It's because Thrax took over the white blood cell in the beginning, White blood cells use inflammation to fight off infections and that raises body temperature.

[@elainaharber8832]

So if an ice version of Thrax screwed with the hypothalamus, hypothetically, would the temperature go down or would it still heat up like Thrax in his normal form?🤔🤔

[@mckenzie.latham91]

The way Thrax operates is, he infects a host, prefects the time it takes him to disrupt the hypothalamus and set the body to crash and burn from a lethal fever, that doctors can’t fix because he’s taken the amino Acid that allows the hypothalamus to control body temp then leaves before the host dies so he can infect another,

[@nancyomalley9959]

"Chris Rock was on a Roll" Sophia, that the best accidental pun I've ever seen! 🤣

[@seiya.power.awesome.inspire]

Ewwwwww......🤭

[@SophiaPhannn]

Omg I didn't even notice HAHAHA

[@nancyomalley9959]

@@seiya.power.awesome.inspire What's so EWWWW about the post? Just wondering

[@BudokaiTH]

Splinter: She made a funny! HAHAHAHA!

[@seiya.power.awesome.inspire]

@@SophiaPhannn Miss Phan, do Spies in Disguise.🙂

[@mckenzie.latham91]

“This cat was sick before i even got here” that line was actually improved by Lawrence Fishbourne (the voice actor for Thrax)

[@frillydress]

THAT WAS SO CREATIVE

[@Mathewrath]

I bet the "sugar pills that cured cancer because they believe they could" is a burn to homeopathy

[@psyhense]

It's a reference to the placebo effect I believe. Humans have some weird/interesting healing capabilities we don't fully understand yet.

[@babycake3655]

This was what I considered comedy gold when I was younger. Being an adult now....it still holds up 😂

[@FormalFilmsProductions]

I feel that

[@matthewkalasky2891]

I agree. It's surprising that it actually didn't do all that well. Even Chris Rock (Osmosis Jones' voice actor) apparently looked back on it with shame for some strange reason.

[@GooftroopSystem2012]

“What the heck is a u-vula!?” “That little dangling thing down in Frank’s-“ “𝗯𝗼𝘅𝗲𝗿 𝘀𝗵𝗼𝗿𝘁𝘀,𝗴𝗼𝘁 𝗶𝘁!”

[@lumisherbert5682]

frank's. WHAT?!?

[@tornadodee148]

I thought she missed that joke because in the vid she spoke on top of it but now I see she liked your comment so now im at peace. lol

[@mjserrano32]

@@lumisherbert5682 Frank’s pe-

[@davecrupel2817]

"Not THAT dangly thing! The one in his THROAT!"

[@simonnachreiner8380]

@Dave Crupel Don’t judge my friend.

[@majiel2709]

Thrax isn't Anthrax, his a disease called the Red Death, his a fictional disease as far as the medical world is concerned, but his an awesome character, some fan made prequel comic about Thrax called Heart Burn.

[@majiel2709]

In all honesty I have no clue, if you take from the Fan Comic which is a prequal to the story of Osmosis Jones but follows Thrax, he was a Red Blood cell that was infected by another Red Death and became a virus that way. But an educated and calculated guess would be that Thrax was once a cell part of the bodies immune system, not Frank but whoever he spawned from. Anyway my guess is that he was some form of immunity that went rogue like proper person rogue and his biological make up changed with him, cause when the body is in pain when it's sick, it's actually the immune system making you feel bad not the illness, so with that in mind, Thrax may have killed his first host and when he jumped ship, his status officially changed from immunity cell to virus since he was a literal rogue organism

[@majiel2709]

Just a guess on my part, don't take any of it to heart

[@joshuahadams]

He’s based on an Edgar Allen Poe short story called “The Masque of the Red Death”.

[@jessicamcneill2463]

Thrax is an awesome, magnificent villain. Kudos to Lawrence Fishburne voicing this (sighs) vile, viral villain.

[@matthewkalasky2891]

@Borat the Yamato The symptoms, from some of the things I've read, at least, make him similar to Scarlet Fever or hyperpyrexia.

[@BudokaiTH]

I keep forgetting how good and smart the daughter was in this movie. Cared for her dad's health more than he did, at a very young age too. Most girls I knew don't give two shits about their dad's health. Lol

[@_Anna_Demidova_]

"Most girls I knew don't give two shits about their dad's health" well, like they supposed to. dad`s need to look after themselves by themselves, they are adults. yes, the girl in the movie is very good kid, but with very bad childhood. her mother died because of the disease, so she trying care for her dad that selfishly don't give a crap about his health while he is her`s only alive parent. very unhappy childhood of a very scared child.

[@katiebread2805]

kzbin.info1dZIFGOXvhU?feature=share

[@nellislost_]

This movie ran so cells at work could appear

[@Mabra51]

But once upon a time... life did it first.

[@randombro89]

I remember in middle school They made us watch this and take notes in science class as if it were educational LOL. Good times 😌

[@rexcabrera8398]

Yesss but for me it was high school, which is... worse 🤔

[@randombro89]

@@rexcabrera8398 Now when this happened it was probably like 2003 I can only imagine How much the public school system deteriorated since. You’re right that is worse

[@rexcabrera8398]

@@randombro89 they really did us dirty af

[@catzmaniak]

@@rexcabrera8398 same

[@flynn5032]

It’s funny bc actual osmosis has nothing to do with the character or the plot

[@FormalFilmsProductions]

You didn’t show the statue of a sperm cell with the label “our founder” underneath it. that always cracked me up

[@Jason-ir5ig]

And I have just now realized that the medicine was voiced by the guy who did Delbert in Treasure Planet. Neat.

[@realar]

He's also Slim from A Bug's Life.

[@warriormaiden9829]

"All my life, I've been waiting for an opportunity like this, and here it is *screaming!* Go Delbert! Go Delbert!" XD

[@mckenzie.latham91]

David Hyde Pierce, aka Niles from Frasier as well.

[@nancyomalley9959]

The main villain in this movie was voiced by Lawrence Fishburn who was in Contagion about another disease!

[@DJtheBlack-RibbonedRose]

Omg I had no idea he played Thrax ('cause I haven't watched this movie in years); that's awesome thanks for letting me know!

[@TheCrayonMaster]

Hey! Other people have seen Contagion? 😅 I saw it because it was filmed here in town 😁

[@nancyomalley9959]

@@TheCrayonMaster Because of the current pandemic, Contagion has gotten renewed popularity since its release 10 years ago

[@TheCrayonMaster]

@@nancyomalley9959 that's pretty awesome! I hadn't realized that 😊

[@captainteeko4579]

I only think of him as Morpheus in the matrix or Crawford in Hannibal so when I found out this was him I was like SINCE WHEN

[@wolfbane7497]

Corona Virus : " look who thinks he's me he tried to kill someone in 48 hours. I was able to cut that time in half I got 50 chapters in the medical books. "

[@morganspider-manmarvelfan6110]

If they rebooted the Ozzy and Drix TV show, they would have to add COVID-19 as a villain

[@stavv222]

I remember convincing my teacher in elementary school to watch this movie in our class cause it's biology related. It was a great win.

[@CloudsAndCoffins]

Ah yes, the movie that made everyone madly attracted to a virus ^^; Guilty as charged. One of my childhood favorites, I remember watching the VHS so much I broke it...

[@AntonioPlays300]

my sister said she thought the pill soldier was damn fine😂

[@DJtheBlack-RibbonedRose]

After this I feel like Sophia should watch Ferngully (1992). Thrax & Hexxus are bit similar in regards to character and motivation but Hexxus comes complete with a bad-ass song.😉

[@steph4753]

I LOVEE FURNGULLY. I think it’s mostly coz it’s set in Australia and kids movies are never set in Aus

[@cityman2312]

Thrax has a better design, but Hexxus has an even better voice. Thrax does have good voicework too, but Tim Curry is adept at playing silly, pompous villains.

[@trashgoblin8885]

Hexxus absolutely terrified me as a small child, but would still watch ferngully as it was so good

[@steph0711]

@@steph4753 there's the rescuers down under at least.

[@honeybizhy]

This movie is a reminder the fact a lot of people had a crush on Thrax including me. Look if you make a villain with a cool design and voice your bond to awaken something.

[@agathaharkness399]

This was the shii in science class😭this and Bill Nye, anything to avoid work really😭😭😭

[@SophiaPhannn]

BILL BILL BILL BILL

[@agathaharkness399]

@@SophiaPhannn🎵 *Inertia is a property of matter bill bill bill bill bill ny ethe science guy* 🎵 lol😭😭

[@drhall343]

If you're looking for underrated half animated, half live-action movies, The Pagemaster is a gem.

[@camerontroutman1605]

Same thing for the 1st Space Jam movie with Michael Jordan

[@mjserrano32]

“The baddest illness you’ve ever seen” When you put yourself in a fanfic:

[@217BLASTA]

That pimple exploding onto her face will forever haunt me

[@madeleinekhouri1655]

This unlocked a sixth grade memory I didn’t know I had

[@roboticcrabanimations3220]

Same

[@captainteeko4579]

2nd grade for me 🤣🤧

[@Gauldame]

This one made me smile. It was silly. If you want to something similar in vibe but a lot more scientifically thorough, check out Cells at Work. I used excerpts from the manga to help explain graduate level immunology to some students. The anime is pretty good too for that, but you have to be Johnny on the spot with the pause button, and in the books they just have splash explanations on pages.

[@choney1168]

You just brought me back to my childhood!! dang we’re old! 😭😭😭 but they made a show about Osmosis and it was one of my favorite shows ever!

[@stephaniefrost4910]

SAME. I loved the tv show!

[@TheNitpickChick]

Absolutely! Ozzy and Drix was a fantastic show! And genuinely educational! There’s an episode that’s permanently burned into my brain about their human (Hector I think his name was?) getting a parasite from eating some undercooked sausages. From that day on I would always make sure my food was properly cooked because I wasn’t risking that nightmare fuel. lol 😖 I also remember an episode about when Hector was freezing out in the snow somewhere, and Ozzy recommended stimulating his muscles to make him shiver in order to generate some heat in order to keep Hector alive. And if I recall correctly, there was an episode where Ozzy went through mitosis. I remember that being a super weird episode, but I still learned something from it! 😅

[@ellyseramirez804]

I have never watched that movie before, but i have heard how it goes. I find it strange that they keep referencing Anthrax as a virus when it's a bacterium. Viruses are made up of genetic material encased in a protein shell and bacterium are prokaryotic organisms. Also, I can be wrong about this but I don't think Anthrax can alter DNA, it just blocks biochemical pathways. However, despite the inaccuracies, it looks like a cute movie and can definitely teach kids about germs and infections.

[@TheNitpickChick]

As far as I know, the villain just goes by the name Thrax, but he’s not confirmed to be Anthrax. I believe he was a fictional disease made up just for this movie, called the Red Death? The symptoms he causes in Frank don’t really match Anthrax so that’s why I think he’s supposed to be different.

[@ellyseramirez804]

Ah. That would make more sense.

[@NightEyeStudio1995]

I both love and am annoyed with this film, mostly by the gross-out humor. BUT it does have some wit and love put into it. Plus all the puns and jokes... I love'em.

[@jennierainyday3091]

This video literally unlocked an old memory I didn't even know I had.😭I forgot this movie existed!

[@Bitt3rh0lz]

The dispatch cell on phone with Jones calls Thrax "La Muerte Roha", spanish for the Red Death. Fun fact, Anthrax is actually known by that name. It was named that due to it causing massive hemmoraging. It is surprising how much in this entirely underrated movie makes sense and is medically accurate. Thrax being Antrax (its in his name even), the way of infection is perfect (Anthrax is a soilborn pathogen, so Frank eating a dirty food item he picket up from the ground is a good way to get it.) Anthrax does have a wide range of infectious periods until it causes death, depending on what form of it you fall victim to: - Cutaneous anthrax (Anthrax of the skin) being very slow acting and of low lethality - Pneumatic Anthrax (Anthrax inhalation and ifnection of the lungs) Highly deadly and fast incubation - Gastric Anthrax (Anthrax infection of the Gastro-Intestinal Tract, through eating contaminated food), which is both the rarest and most deadly form of Anthrax , so that lines up as well. Frank in this case would mostly likely suffer Gastric Anthrax. I got to give credit to the writing team behind this movie cuz they sure did their research.

[@ryankramer8779]

Correction: it's spelled "roja." H in Spanish is silent

[@TheBlackAntagonist]

16:02 I do NOT remember that face. Good God, why is this movie not in more memes? Blasphemous!!! BLASPHEMOUS I SAY!

[@matthewkalasky2891]

It recently came on Netflix. Don't know if that's triggering anything along those lines, yet, but I'd hope it would.

[@TheBlackAntagonist]

@@matthewkalasky2891 Ah good. They deserve it.

[@KaleFGB]

I will never stop until you watch The Secret of NIHM

[@lilscenechick1995]

Omg that one is so underrated. I understand it's definitely an intense movie for kids lol but it's so good

[@ipsyscipse]

"I just know he's gonna wipe it on his shirt or something. What is he gonna wipe it on- AAAAAAAA" I can't stop laughing; that reaction was pure gold.

[@KingdomheartsII]

The zit erupting was such a classic.

[@lovelilavalamp1182]

I used to be terrified of this when I was little, I think it mostly scared me when going inside the person, but now that I'm older and have dissected countless critters and seen worse stuff, both irl for science and both fictional. Glad to see it again

[@capnjojo5604]

OKAY SO IS NOONE GONNA TALK ABOUT THE FACT THAT 22:11 WAS AN ADULT JOKE THAT TURNED INTO ANOTHER ADULT JOKE??

[@LyraCross]

I am in love with the character design for the Anthrax.

[@saraislfe14]

Yoooo I used to watch this movie every year in health in middle school and in my health class back in my first year in highschool😭

[@kelvin-h]

OH MY GOD I WAS NOT READY FOR THAT INGROWN TOE NAIL FEET SCENE AHHHHHHHHHHHHHH

*"Virus con Dios"* Now that's a one liner.

[@lillordakira9752]

Did you know that the movie was suppose to be Rated PG-13 before Warner bros decided to go with a PG rating ? Most of the swearing had to be edited out and redubbed during post production. For example, the "shortcut" deleted scene Jones was originally going to say " WHAT THE HELL IS A UVULA" instead of heck in the final version. Other deleted scenes involved Ozzy and Drix visiting the Eye as a amusement park called "See World" and an extended version of the nose where Frank was picking his nose.

[@ArcherA]

Can't deny the main bad had a great design

[@skittlesandsoda08]

It's a bit sad, cause like in the animated show (Ozzy & Drix) Frank never really improved on managing his health. If anything it got worse u_u

[@nathanielrodriguez1873]

I think they explained that it was a different continuation.

[@TheNitpickChick]

I thought in the show they were carried by a mosquito to a different human? A kid/teen boy? Am I remembering that wrong?

[@skittlesandsoda08]

@@TheNitpickChick you're right. I was talking about before they got suck up by the mosquito.

[@TheNitpickChick]

@@skittlesandsoda08 ah, that makes sense. I didn’t remember that part of the episode, but then again I haven’t seen the show in over a decade. 😅

[@matthewkalasky2891]

I've recently read an idea that the fever may have given him brain damage, and, therefore, prevented him from retaining any "character development" inducing memories.

[@hi_sayri]

Lmao Drix dancing at that club reminds me of Zemo dancing in The Falcon and the Winter Soldier 😂

[@UnluckyAmulet]

"Big daddy Thrax is gonna let you have it." EXCUSE me?

[@trollipop1867]

In reference to where chris rock went. He did a lot of documentaries some produced by himself too. So he was doing a lot of background stuff before all the voice work in Madagascar. He also kinda got blacklisted for a few years. Also fun fact: because of his role in new jack city there was a time where fans would actually give him crack cocaine cause his acting was so convincing.

[@Zontois]

Looking beautiful as always! I don't remember this movie but I remember being traumatized for some reason 🤔🤔🤔

[@egranger2128]

Thrax was my first cartoon crush

[@eternyti]

Am I the only one who had (and still has) the hots for Thrax? It is not a good sign when you find a dangerous virus attractive 😂

[@udawg34]

This movie is such a childhood classic, I'm not ready for this!

[@matthewkalasky2891]

It wasn't, officially, but it certianly SHOULD have been. (I mean, in regards to the critics, and box office receptions)

[@lifemattersnot]

I cant believe Id never seen the peace in the middle ear poster this is why i watch these videos top quality content

[@Liberperlo]

Loved this movie cuz of the juvenile humor but also love Cells at Work for the action. The best description of Cells at work is "older Japanese brother of Osmosis Jones"

[@henreebee6561]

This is such a creative concept for a movie! I remember loving the show that came after this, Ozzie and Drix, as well.

[@tazm2480]

Dude what a classic this movie is super underrated and I loved this movie so much

[@nataliarobles3815]

Biology students do suffer, i can confirm 😔

[@phousefilms]

Thrax is still one of my favourite villain designs and villains in general.

[@soychidoese]

Check out Doctor Hope's Sick Notes reaction on this movie, he gives a medical analysis on what they got right and got wrong. Otherwise, another good video!

[@juanelo1332]

I have literally been waiting for you to do this movie!! So excited!!

[@silviarueda4344]

you have no idea how long I've been waiting for a KZbinr to react to this gemmmmmm

[@frillydress]

This entire movie makes me so happy, I’ve rewatched it at least 100+ times and it never gets old 😭🙌

[@hotburritoxxx9146]

Keep reacting to old animated movies, I totally forgot this existed

[@Melissa-wx4lu]

I love those movies you always assume were dreams you had fighting a fever when you were a kid. I had the strangest memories that turned out to be from the movie Raising Arizona. Also, Batteries Not Included was a movie I discovered after searching out odd memories I had as a kid.

[@DJtheBlack-RibbonedRose]

Just wanted to say, found your channel in recent weeks & I really enjoy your reactions. 🥰 And this was quite the timely reaction because I myself just caught the new trailer for Spiral too. 👍

[@PopRocksOTP]

sophia is just going on a content stream, and im just sailing with it

[@skullgamer64]

If they made a sequel out of this now it'll be more interesting they might even feature a corona virus as the antagonist.

[@vanessahernandez7605]

OMG Sophia, I thought I was the only one who watched this on their VHS as a kid. Great commentary and can't wait for more to come 🥰

[@RXone2one]

I'm 29, and this was the one movie I remember wanting to go see. Never did but I'm glad to see more than a minute through you're video sister!! Omg I laughed so much with you're commentary. The bessst!!👌🏻

[@coryneff7048]

Ayyyy. Like the leaves added to the background. Also glad to see another Cells at Work fan

[@Pako_equis]

Dang i forgot this movie existed its a good one. One i came across not too long ago that now i consider underrated is James and the giant peach

[@davecrupel2817]

That face Drix made at 16:00 was one of the most memorable faces I've ever seen in a cartoon. That shit was etched into my memory forever 😂

[@finight_bluejosh8238]

I remember watching this movie as a kid and always just assumed it was something I had a dream about, like a dream that seems so real to the point you confuse it for a memory kind of thing xD.

[@EmperorChaos468]

I remember watching this in highschool in biology it supposed be educational or something and I was quoting the movie. I feel like its underrated and so good. As a former biology major I did feel like I was going circles and crazy, I switch for to English now and my stress has dropped compared to before.

[@hazelonnutella9599]

Yass!! Loving the background evolution 💚💚

[@anf9311]

Currently in finals week and battling Moderna dose 2 (ozzy help 🤒..) cant wait to binge your vids when its all over!

[@diamondbaker5331]

I forgot how insanely dark this was

[@matthewkalasky2891]

I know, right? The way the cells, and Thrax, disintegrated? A lot more brutal than I remembered.

[@zaphenath5915]

Yeah, I remember this turned into a show but I definitely thought it was some some weird fever dream I had at 5 that's been hiding in some dark corner of my mind lol.

[@harprabhsangha5177]

Omg what a nostalgia trip. I was so young when I watched this. I also as a kid thought I made this up in my head.

[@patrice1016]

Love the background💕

[@DJtheBlack-RibbonedRose]

Ah, this certainly brings back memories of 5th Grade Science & just being glad we were watching a movie instead of a slideshow we had to take notes on. As well as remembering years later that Bill Murray played the dad and it was probably my first introduction to him in live-action after his work in Garfield. 😆👍 I was born in 1999 and mostly watched Barbie, Disney, & Scooby-Doo content so go easy on me on the last bit. 🙃

[@julianlastname6948]

i remember watching this in school and my friends and i thought the characters were cute😭

[@Vancy_And_Andy]

Loving your work Sophia.

[@unkown34x33]

I was afraid to watch Ozzy and Drix when I was a kid (the Spinoff of osmosis jones) but now as an adult, I watched all the episodes and the movie with more details. it's pretty rad, and Fairly accurate sometimes :) 90's I miss these days

[@agenttheater5]

11:11 He's the Red Death - don't know if that was ever a thing that's supposed to have died out years ago or a name of a disease they've since learned more about and subsequently renamed. In any case, he's planning on being one of the bigger diseases now.

[@matthewkalasky2891]

I think (I repeat, THINK) that Thrax was a fictional disease.

[@glitzdancer]

This is one of the few movies from this time that had an actual good tv series spin off come from it

[@GabrielDalposso]

weekend starts whenever Sophia uploads a new vid :)

[@derekwall5570]

This girls a QUEEN 👑

[@martinacosta3821]

Titan A.E. please, pretty please with a cherry on top hehe

[@lifemattersnot]

Second please.

[@sydneytalks4254]

They showed this movie so much in my elementary school that i thought it was a fever dream

[@OwlKitto]

16:00 😳 *Dear god i hope this won't make me feel Weird in ways I can't describe and...* nevermind it already happened. Why-

[@frillydress]

OH MY LORD

[@ggnicklu]

I THOUGHT IT WAS MY IMAGINATION TOOOO OMGGG This is a trip

[@jessicabluanythingnerdy]

Love your videos! The Pagemaster is a great movie

[@isabellechurchill1391]

this memory was LOCKED away damn, this movies crazy

[@Rose-po2vd]

this brought back a dark memory of 7th grade science class

[@milkmanlol258]

Thank you for this amazing content

[@plainrosiejane]

omg finally someone watched this !! 😭i loved this movie as a kid LOOOL

[@jacksonsd_]

this movie reminds me of the end of the school year/beginning of summer fun times because the last time i watched it was the end of 8th grade when we finished all our work lol

[@LookMyMoonEyes]

I have never seen this movie in english so I didn't know that green bacteria thingy speaks spanish!! I live in Mexico so the movie was in Spanish and there's no leguage barrier in that scene

[@frillydress]

Did Thrax still sound sexy in Spanish 😳 (just curious)

[@jazzyj3059]

Ah this was and still is one of my favorite movies from when I was a kid