Dr. Rob Edwards from San Diego State University describes Pacific Biosciences SMRT single-molecule long read sequencing.
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@habeebshaik69664 жыл бұрын
Such a need and organized presentation. Great composure. Thank you.
@loljoker1274 жыл бұрын
Really well put, thank you making it so visual too!
@jkuo51503 жыл бұрын
Well organized. Easy to understand PAC Bio's data sequencing technology. Thank you!
@jaredbernard15824 жыл бұрын
You're great at organizing and presenting this material. Honestly, I'm even more impressed that you can seamlessly write backwards and inverted! No wonder you're good at teaching transcription!
@christopherhall36454 жыл бұрын
Surely this is sarcastic? Why would they not just invert the image haha.
@mayascull98573 жыл бұрын
@@christopherhall3645 Thankyou for explaining this! I feel so dumb hahaha
@sofianaftalynathan13862 жыл бұрын
Clear explanation and great presentation! Thank you! :)
@she_is_a_hungry_raccoon5 жыл бұрын
GOD BLESS YOU AND ALL YOUR FAMILY SIR
@nom3nnescio3 жыл бұрын
this is science, take your mumbojumbo nonsense away from here
2 жыл бұрын
@@nom3nnescio can you explain to me where the laws of nature come from?
@nom3nnescio2 жыл бұрын
@ by observing what we see/measure of course. Have you ever heard of this thing called science?
@nom3nnescio2 жыл бұрын
@ or do you think your god is real? lol, it's not. It's just your imagination and you probably learned it from your parents. There is milloins of gods recorded, why only yours (out of millions) is the only and real one? Why don't you believe in other ones?
2 жыл бұрын
@@nom3nnescio laws are abstraction of patterns we see in the universe. what i meant was: what makes the universe be ordered, rather than chaotic? Where did the universe come from?
@yarasilva61383 жыл бұрын
This is increíble. Thank you!
@minhthuonglethi98744 жыл бұрын
Thank you very much for videos.
@kareemjeiroudi19644 жыл бұрын
Wow this guy has become my favorite professor 😉
@ewittka100 Жыл бұрын
Very nicely explained. Thanks.
@MrSeonyeongkim4 жыл бұрын
very much thank you sir
@user-gv6bh4wj8i4 жыл бұрын
Wonderful explanation, and amazing left-hand mirror writing!
@ilhambenkharfia68745 жыл бұрын
I got nothing what's the relation between pacbio and phospholinked nucleotide and zero mode waveguide ? And thank you
@SaintNath4 жыл бұрын
Thank you for the nice explanation you saved me a lot of time with summing this up. I have read about a MinION device using electric current for nucleotide detection. In the video you talked about fluorecence. Could you explain the relation for me or is it simply two different technologies?
@microbi02964 жыл бұрын
It's different technology. It's called Oxford Nanopore. I'm learning about sequencing and came across this article about different technologies. I found it helpful. www.sciencedirect.com/science/article/pii/S0888754315300410
@bs7shorts7294 жыл бұрын
Sir, very informative vedio, hepl me distinguished between illimuna and pacbio rsII
@yanjunhuang40793 жыл бұрын
The Polymerase do have the ability to synthesis 1000bp/s, but i have seen many online material said that it is only 3-10bp/s. And it is also very not logical since it will be pretty hard to assemble fragments you described above. So is this really correct or is there technology that control the polymerase reaction rate.
@evoJohn753 жыл бұрын
Yes. The polymerase is slowed down to about 2-3 bp/sec. Much of Pacbio r&d is in modifying polymerase. The description here is a bit off, although otherwise very well done. The whole insert is sequenced each lap around the template, not little bits. There is significant indel errors at single pass accuracy, but they mostly go away with >3 passes