#Pharmacophore

[@Shyamsundar_Ind]

thank you sir..very useful video

[@rajkhunger]

Good one

[@Dockingbydushyanthreddy]

Thank you very much sir

[@bharatsahu7983]

THANKU SIR, I HOPE YOU DOING WELL SIR

[@Rome532]

The best

[@Dockingbydushyanthreddy]

Subscribe and share my lectures with your friends and others feel free to contact me on Watsaap 8919754133

[@Rome532]

@@Dockingbydushyanthreddy I would like to work with you I researching of COVID 19 and. I have important results but I defines valided docking with RMSD my email [e-mail] if you wanti we works together e have a lot big publications let me know so I can send my research e Finished work of Covid 19 I am studying COVID 19 quite 1 year

[@hennysriwahyuni9953]

Hello sir, I hope you are doing well. Could you give me a step-by-step from first how to do pharmocopore modelling and how to make the structure from pharmacophore modelling results? Thank you

[@Dockingbydushyanthreddy]

its already there refer to all my videos u will get the answer

[@Chemoinformatics]

This is a useful video on how to create a structure-based pharmacophore kzbin.info/www/bejne/sH7IenWrgtt-grc

[@yasrafatima5230]

hello sir! hope you are doing well ! sir i don't have an access to generate pharmacophore automatically i have discovery studio installed in my laptop but dont have automatics pharmacophore generation in that . kindly tell me what to do

[@Dockingbydushyanthreddy]

You have to purchase the software ....

[@yasrafatima5230]

@@Dockingbydushyanthreddy but i have this software already installed in my laptop but i don't have access to this feature specifically

[@Dockingbydushyanthreddy]

@@yasrafatima5230 software works with license without license it is restricted usage ....

[@apoorvamkulkarni5737]

how can the pharmacophore be generated only with the protein structure assuming we know the active site residues but have no ligand-protein structure

[@Dockingbydushyanthreddy]

Protein Ligand Complex are necessary to generate pharmacophore when its SBDD; u can do Ligand based with standard drugs that is called as LBDD

[@jahangirahmed9335]

How to make ligand library in discovery studio and how to check error in those small molecule preprocessing steps

[@Dockingbydushyanthreddy]

Contact me on Watsaap 8919754133

[@elainejoytorre2191]

is this ligand-based or structure-based pharmacophore modelling? Having a hard time differentiating the two. Thank you

[@Dockingbydushyanthreddy]

It’s interactive ligand in the receptor pocket ... it comes under the category of structure based pharmacophore model .... if you like subscribe and share my lectures with your friends and others feel free to call me on WhatsApp or email at 8919754133 dushyanthreddy233@ gmail.com

[@Chemoinformatics]

This is a useful video on how to create a structure-based pharmacophore kzbin.info/www/bejne/sH7IenWrgtt-grc

[@saramahrouk2528]

When I try to display a 2D diagram of the ligand in Discovery Studio, I receive an error message saying 'Ligand is not a single fragment' and I don't know what I need to do. I need help to resolve this issue.

[@Dockingbydushyanthreddy]

dear student, u have to make structures with proper drawing tools and structure conversion toll to clear the erorrs

[@veenasukumaren6803]

Sir, is there any validation step required after performing this experiment.

[@Dockingbydushyanthreddy]

VALIDATION IS DONE BEFORE DOCKING

[@AbdulrahmanMSaleh]

Great . Can you send me the liscence of biovia discovery studio

[@Dockingbydushyanthreddy]

It costs 12-25 lakhs in Indian rupees if interested let me know

[@AbdulrahmanMSaleh]

@@Dockingbydushyanthreddy price in dollars pls .

[@Dockingbydushyanthreddy]

Indian rupees varies From nation to nation

[@AbdulrahmanMSaleh]

@@Dockingbydushyanthreddy i know that .so that pls tell me the price in us dollars

[@Dockingbydushyanthreddy]

@@AbdulrahmanMSaleh you may contact local dealers ....I know dealers of India only

[@uzmazeeshan1010]

THANKS FOR EXPLAINING THE EVERY STEP IN DETAIL. I HAVE DISCOVERY STUDIO SOFTWARE BUT CAN'T ABLE TO ACCESS TO ADDITIONAL FEATURES DUE TO UNAVAILABILITY OF SERVER. CAN YOU GUIDE ME IN THIS SCENARIO FOR SOLVING THIS ISSUE, KINDLY PROVIDE ME YOUR EXPERT OPINION

[@Dockingbydushyanthreddy]

Please subscribe and share my lectures to your friends and others who are in need contact me on Watsapp India 8919754133 [e-mail]