Pathogenesis of Atherosclerosis

[@DAR0.V]

I always come back to this video whenever I forget the visuals of this pathogenesis. It is so simple and well created! Thank you!

[@jmjm3882]

Same same watched it in 2nd yr for pathology now 2yrs later for medicine

[@jessicathorpe2855]

If it wasnt for this video, i would never understand atherosclerosis, thank you very much for telling the story of atherosclerosis

[@EthioBelle]

Concise and perfectly animated and narrated, THANK YOU for this incredibly helpful video!!!

[@Linacyrus17]

The video was amazing!!!! Will def rewatch a few more times in preparation for my patho exam! Thank you!!

[@mikaelahetherington7301]

This is brilliant. I've been searching for days for a clear explanation of this... sifting through text books, google and journal articles. In 6:05 minutes you have made it all click. Thank you.

[@physiopathopharmaco4190]

That’s very kind thank you very much

[@keishael5582]

Watched for the first time and u held my attention all the way through. Like your voice and animations. Will share with other nursing student. Not everyone can teach good video. Please release more.

[@MedMicroBioMe]

My exam is in an hour. Thank you for simplifying this and filling in my knowledge gaps.

[@physiopathopharmaco4190]

Best of luck!

[@W_Titan]

This video is so amazing. It makes the concept so easy to grasp. Thank you so much for this masterpiece

[@FolkenSRK]

Good job, sir. I wish my teacher could explain it like you did.

[@mukamarihoamon1377]

I know right......

[@calpolyca]

This man's narration is at the perfect speed to really understand this!

[@kirsten7883]

awesome illustration!! my brain was able to connect all of the dots with the help of the animations

[@GoodNewsForStrangers]

At seems to me that every video I watch has different levels of detail on the same concept and the ones that express the most detail such as mentioning WHY certain things happen as opposed to "lipid just oxidises" and "A blood clot then forms" are the best ones. and I cannot learn and understand concepts that superficially. I have to know the details and this video does a good job of going past the details given in my specific lecture giving me a more understanding which means better chances of remembering! I am set with this. Thank you!

[@fortcastlevgn2368]

wfpb diet is the only thing that can cure almost all deseases of our rich societies,, mostly raw even better (vegsources on youtube,, many doctors explains in detail (dont think that much in detail,, but im too dumb to get it so i hope you can follow their explanations better then i can

[@bio366geethasankar7]

🙏🙏🙏😊

[@adnertga6559]

Who tf picks that kind of username? “ Jihad”.

[@alexx_93]

@@adnertga6559 what's wrong with it?

[@adnertga6559]

@@alexx_93 Take a wild guess

[@heatherwilliams90]

Brilliant thank you, I have been reading a lot but it just didn't make sense to me, this helps so much being able to see it. Thank you

[@physiopathopharmaco4190]

Glad it helped!

[@physiopathopharmaco4190]

Glad it helped!

[@makahhd5530]

well done bro ,I watched 1 hour lecture my doctor and your video only 6 min soooo help me to understant thank you❤️❤️❤️

[@ruchaj1748]

Saved my 30 mins of reading thru the book. Thank you

[@physiopathopharmaco4190]

Awesome thanks!

[@sarahprosecco]

Thank you for such a detailed informative video! best one i've watched on the topic. Subscribed!

[@myrcene22]

This was so helpful! So on point and easily understood. Thank you so much!

[@janaabhilash4577]

Thank you soo much sir ❤️ lot's of love from India

[@madalinaciobanu7583]

Best ilustration from youtube imo

[@malihachowdhury7323]

I clicked like on an educational video for the first time. What a year of change.

[@physiopathopharmaco4190]

Awesome best of luck in your pursuit of knowledge

[@wedeyforyou]

So that’s what my professor meant 😅

[@HAYANMA-cz4of]

I loved this video the animation and the perfect and simple explanation was made it very easy for me to study this topic. I really really wish you could make more such video with this type of clear and simple animations and explaination of o pathogenesis of other disease also it really help us students a lot to study. My teacher actually recommended this video.

[@Flawleras]

The best explaination of ATS formation ive ever watched !

[@anirbanpaulrollno6067]

Thanks sir for explaining the concept in a very nice way ❤️

[@lubnaabdalla9925]

Simple , clear with intelligence way 👌

[@MrAlvarez23]

I just saw your video Sir, it was straight to the point I read the book and couldn't understand it. I took everything u said lmao. Thank you having a quiz on Wednesday for CAD

[@cooker4000]

Excellent. Watched this with my daughter, and it has motivated me not to miss taking my cholesterol medication.

[@physiopathopharmaco4190]

Excellent, that’s great

[@danielzulujr7375]

Thanks,my lecturer couldn't even dream to explain it like this.😂

[@Debt-tective]

So succinct. Great video

[@asadullahkhan3825]

You are amazing! Your videos are incredibly helpful. Such smooth voice and fantastic animation!

[@physiopathopharmaco4190]

Thanks, that is so kind. I really appreciate it :)

[@renatapeters3681]

That was brilliant. Thanks! I saw a photo of cholesterol building up so much that it formed sharp crystals underneath which then cut and burst through the endothelial lining.

[@lourdesdelpilarsanchez9964]

Brilliant explanation, thank you!!

[@jessyn9461]

Thank you so much ! This made me understanding what my lecturer has been teaching all the while 😂

[@nazliidris9052]

Those summary quizzes are the best idea for an educational medical lectures video. Hope to see more of those in the future

[@physiopathopharmaco4190]

Thanks for the feedback; glad it was helpful

[@tiennhat1034]

This video helped me find the answer that I have been looking for the whole time. I even tried to look up but I could barely understand. For example, where do oxidized LDLs come from? Why there are macrophages in the tunca intima? I am so so grateful!!!!!

[@ucchi9829]

Tiến Nhật LDL and other lipoproteins can become oxidized through a number of ways. Reacting with ROS, glycation, binding to proteoglycans, ect. Oxidized LDL in the blood plasma isn’t an issue in this context. It’s only when it’s oxidized in the intima is it a problem. Monocytes will travel through the Endothelial into the intima and become macrophages. OxLDL being trapped in the intima triggers them to come into the intima.

[@joseftraunmueller3844]

Eating too much oxidized polyunsaturated fats, oxidation continues in the body. When ApoB receptors are damaged (by oxidation or glycation), the liver can't identify the LDL any longer, they keep circulating until they crash. To me this is a much more credible description than "too many LDL".

[@AnjorinOmotola]

Omg! This is absolutely amazing! High five ✋

[@dr.m162]

Amazing explanation. Thankyou so much.

[@euscieu4246]

Thank you so much! This is such quality material you’re presenting. Subscribed! Look forward to seeing more of your videos.

[@physiopathopharmaco4190]

Thanks, very much appreciated

[@isabella-rose]

Thank you so much! This really helped me understand the concept before my exam. 🤗

[@physiopathopharmaco4190]

Glad it was helpful. Hope you ace your exam

[@riyaaaaa748]

Wonderful explanation

[@raymondpatricio713]

Very well explained. Thanks.

[@shehamgilani4119]

Wow never understood it so well! Thankyou for this!!

[@belzavmaya]

Thank you your explanation was detailed and very helpful.

[@shimgunawardane4289]

this is just so good, thank you!

[@rabeldas2302]

Best explanation, easy to understand thankyou so much

[@rorangarrowsson2078]

I can't believe this doesn't have more views

[@eugeniostreliaevfilho8904]

TOTALLY AGREE

[@hassanhaidar7302]

Excellent Video.

[@ma_dd]

That was an awesome video! Thank you

[@sangavi.s2588]

Very very useful animation. Keep doing more videos sir❤

[@physiopathopharmaco4190]

Sure 👍

[@tasnimtabassum2088]

Amazing! It cleared up the concept very well. :)

[@ambili.p.p702]

Very nice presentation

[@ALFG65]

Very good explanation and animation. thank you

[@physiopathopharmaco4190]

You are welcome!

[@MaeV808]

😭. Thank you. My prof doesn't do visuals. He does very word dense and lengthy ppt lectures.

[@rethijja3331]

I looooooove your content thank yoooooou I'm so happy that we have you

[@rethijja3331]

I'm here again

[@sumithalder4956]

A very good job guys ....just loved the video ❤️❤️

[@physiopathopharmaco4190]

Awesome, thank you very much

[@janhaviborkar8287]

Amazing explanation 👍🏻👍🏻

[@ayeshaabid1189]

Superb ❤

[@embiembi3435]

Thanks for the video, just wondering can LDL build-up in the artery wall still occur with healthy endothelial cells or do all atherosclerosis begin with damaged endothelium? Thanks

[@LucasSousa-yc4pr]

Thanks, it was really helpful!!

[@physiopathopharmaco4190]

Glad to hear that!

[@هالة-ش3ب]

new subscriber💙✨

[@thecountryboymack]

Fantastic video it really helped explain Atherosclerosis to me!

[@physiopathopharmaco4190]

Great glad it was helpful

[@Poddle_e]

This was so great!!!! thank you

[@sheenacana2386]

THIS IS VERY INFORMATIVE. THANK YOU!

[@cynthialoforte8123]

Such a good explanation

[@eduardoduarte630]

Perfect! Just perfect!

[@rethijja3331]

My favourite explanation

[@marinacagnon1442]

OMG, this is PERFECT !

[@Mohammad-xe2qw]

Good job 👏

[@منارباسلمرادعبدالأمير]

Perfect explanation ✨

[@alexanderschretzmayer6022]

Brilliant Video Thank you!

[@karishmahalai3886]

Short and easily understanding.... Thanks sir

[@physiopathopharmaco4190]

Thank you very much for the comment

[@basmawahab879]

This was great !

[@muaazalizahid3961]

Thank you so much, You Expalined like a pro..🔥

[@bdictjames]

Thank you for that! This is very informative.

[@jayariesgianan3160]

very good explanation

[@goldensparrow4076]

Thank you! It was informative and fun to watch.

[@physiopathopharmaco4190]

You’re very welcome!

[@atwijukireedgar8749]

Amazing 😍

[@peckdec]

Impeccable video

[@alicealice_]

Very concise 👍🏻👍🏻👍🏻 it helps me understand very well ! Tqvm!

[@Kyoze0]

Thank you. Very good explanation

[@physiopathopharmaco4190]

Glad it was helpful!

[@lisbethsalander1723]

Could you do a video on what steps to take to prevent or minimize initiating the process in the first place? This is a worry of us - the senior group. Your explanation is easy to understand- hence the request for you. Thank you so much.

[@MiddletoM]

switch to a low carb diet. This way you minimise the amount of glucose in your system which damages endothelial cells. There are many, many other reasons why a low/no carb diet is beneficial for your health. I really do encourage everyone to do some research on this. Its a very interesting rabbit hole to go down.

[@infj.creature]

Smoking is also a huge factor, if you smoke please quit

[@lisbethsalander1723]

@@infj.creature Thank you for your reply. I dont smoke so that is somewhat reassuring.

[@moreofshalom]

Gr8 explanation. Thnk u

[@physiopathopharmaco4190]

Thanks 🙏

[@iranjackheelson]

1:35 is the atherosclerosis via high blood sugar also identical process or different?

[@Sithu-1112]

Thank you so much ❤

[@dysmayado]

Well explained and concise :)

[@physiopathopharmaco4190]

Thank you Gladys🏅

[@asmaa2786]

Great explanation , thank you 😊

[@htchoco]

tysm! this was easy to follow

[@gmalatraining6235]

Thank you very much for this video

[@garrywelch4041]

There seems to be so little focus in these similar models on the initial irritation and damage to delicate arterial walls. High BG, HT, etc are mentioned but surely the number of irritating sources are much higher in modern living and interact- so the blood flowing through arteries today is like a sewer from the thousands of industrial chemicals in our foods, air, personal products, and inactive ingredients in pharmaceuticals. It would be helpful if these types of models connected the problem with the upstream causes from our industries. The model is very clear about what happens if we dont turn off the poison coming into our bodies. Thanks

[@ahmetkeyan3346]

thank you it was very good explanation

[@physiopathopharmaco4190]

You are welcome!

[@nazliidris9052]

Very helpful video lecture! Thanks a bunch!!

[@physiopathopharmaco4190]

Your welcome Nazli, all the best 🙂

[@infj.creature]

Thank you so much!!

[@parinithamaben4141]

Beautifully explained!

[@physiopathopharmaco4190]

Thank you

[@zakirzak1494]

❤great video thank you

[@dennerdovandojr.8878]

Excellent. Thank you

[@deyatresdewalt5099]

Can we get this man to 100,000 subscribers? This 6 minute video explained 50 slides in my lecture.

[@clemlee4641]

This was so good!! And it helped a lot Thank you!

[@yokeshkaliaperumal2012]

Sir, I salute you.

[@rukhsarq.8612]

Superb explanation... Thank u so much

[@physiopathopharmaco4190]

Thanks

[@ciaramoloney9190]

This is so helpful and explains fantastically what I struggled to understand from my powerpoint presentation. Would you be able to tell me how collagen plays a part here? According to my slides, smooth muscle cell proliferation occurs due to further endothelial damage from oxidative stress from fatty streaks - this then leads to collagen production . Would I be right in saying the collagen forms over the hardened plaque in this instance, and the thrombus attaches on top of it? Or is collagen part of what forms the plaque? Any help would be appreciated! :)

[@sthembisomthembu4183]

the proliferation of smooth muscles and collagen is also caused by PDGF produced by the platelets