Post-Transcriptional Modifications of mRNA

[@Baluwa_]

You must know you have saved my med school life.

[@valeaves]

Cynthia Mali Mine too!

[@AngelA-bb5jl]

Dude I wish I had you as my professor. God Bless

[@junaidhasan8215]

you might just save me from failing my biochem test on transcription and translation. There's no time left to read books so i resorted to listening your lectures, the decision i'll never regret. You have given me hope. Thank you! Keep up the good work!

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How did you do on the test?

[@quintonwilson8565]

Transcription in AP Bio, transcription in microbiology, transcription in genetics, transcription in molecular biology, transcription in biochemistry, UGH!!!!!!!!!!!!!!

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Why doesn't this have more views?? This is great!!

[@emilygreen2436]

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Two minutes into the video and wow youre really good at explaining!

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[@Matt-re4et]

I really enjoy the videos, especially the fact that everything isn't shoved into one video but a series of videos. I'm only in gen. bio. 1 but this is very helpful.

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you are amazing! you know exactly how to explain, and from which points you should start and finish. Thank you a lot!

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[@lawyerdoctor]

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Thanks so much for these videos!! You are a great teacher, and are great at explaining these processes. You are saving my genetics grade!! :D

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Sir I wish u would be my professor 👨‍🏫. U teach so well sir.. Thank you so much..

[@motivationtostrive1216]

God bless you for saving me and the rest of us you are so underated God bless 🙏🙏

[@llennzo]

Exons are expressed intros are in the way. This is a great phrase.

[@mohi7527]

Thanks. I wish you were my professor.

[@renoreno8755]

Great explanation Thank you

[@catherinsebastian8162]

You must know dear 🤝🏻 You are Just Awesome 💕🙌🏻God bless🧚🏻‍♀️

[@thereal7490]

good explanation as usual but the process of splicing is quite complicated and needs to be explained with some more detail thank you

[@mohammedal-hammadi5085]

I appreciate your efforts really, so great lectures, thank you so much

[@kiimi1614]

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Wtf

[@tonuinicholus6395]

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[@smithajohns77]

what a nice teaching""""

[@inesgonzalez2246]

Awesome lecture 👌

[@michaellouis4882]

I have a question. on the last part of splicing the exons, you mention about the poly(A) tail also spliced in the nucleus. And it is also mentioned before that, poly(A) tail aids in the transport of mRNA across the nuclear membrane. So, my question is why the poly (A) tail is spliced if it actually aids in the transport? or is it because its long structure is degraded gradually during the travel? Thanks in advance.

[@andellahypolite]

Clear and Succint! Thank you

[@mostafaali8108]

thanks.very helpful videos

[@samirgeorges2686]

Absolute masterclass

[@epicmoments1964]

Well explained. Thanks🙏

[@adsingh54321]

thank You so much Andrey !!! sir this video is very HELPFUL

[@davidfell9696]

Another excellent explanation!

[@abramovicsta8434]

Absolutely perfect thank you very much

[@zeevgolin2984]

Great videos and very informative ! Thank you.

[@dyoomah17]

Thanks alot 😊 .. what is the thing that is responsible for adding the cap and tail ?

[@AKLECTURES]

You're welcome! Not sure if there is a specific name for that complex but its basically a collection of different proteins and factors that work together to add the poly A tail and cap.

[@jamesfleming4525]

dyoomah17 Cleavage and polyadenylation specificity factor

[@malikid1000]

The methyl transferase is the enzyme which adds the methyl group basically the cap on the 5 prime end. The polyadenylation occurs through binding of cleavage stimulatory factors which recruit cleavage factors which cleave the mRNA. The poladenylations then begins with the addition of adenine residues by poly A polymerase (PAP).

[@adyanwains8443]

HY! I have a question.u said splicing occur after adding caps and tail.but i said splicing before occur then add cap and tail.basically cap meaning protect if splicing after capping occur then cap not protect mRna?am i right or not?plz answer my question.thanks

[@mpc7440]

One little nit-pick, on the diagram of the pre-mRNA, the introns look relatively small compared to the exons. In reality, introns tend to be far longer than exons (I say "tend" because their size varies). Again, just a nit-pick that I think is worth mentioning.

[@astro8149]

THIS HELPED ME SO MUCH

[@adyanwains8443]

I have read many books for this question.but one book writer write first splicing then add caps and tail?

[@aleynaa3420]

can you tell me in what order these processes happen? is it the order you explain in the video? Excuse my English i know it is not good :)

[@instastoriesnupdates3080]

Keep it up sir

[@liopolt0915]

Thx for video, it helps me a lot :)

[@AKLECTURES]

Reza Pratama Nugraha you're welcome! :)

[@mmaking8664]

Can you please describe a coherent order in which to watch your videos, like what to watch before watching another video?

[@MrShaiiix]

AK LECTURES very helpful concept

[@MrShaiiix]

Shallu Chauhan thnxx a lot

[@Kyrani99]

Thanks Good lecture, good explaining. Just please make writing bigger and don't put so much on the screen at once. It makes it very hard to read even on a full screen setting.

[@malikid1000]

Good explanation but would have been better if you mentioned the enzymes involved in each step.

[@hamedhosseini4938]

God bless!

[@AlanRasoulMentor]

hi du have any vedes on chemistory from beginning because am rubish with molecules and bonding stuff, i wanna start from the begging of understanding atoms, thanks

[@prathyushasrinivas5008]

thank you ! it was very helpful

[@manushoganyan6302]

Thank you so much! Very helpful!

[@carolinemangare3071]

Great job

[@nada.h.majeed]

Thanks brother 🌼

[@kanikabhardwaj7719]

thks for clearing thoughts

[@BioAffairs]

wow sir detailed information

[@1028Sukmawati]

What is the difference between gen and exon?

[@colmmcgurk3742]

I could be wrong , but i think you've made a mistake here. The exons are actually the coding regions for proteins! Introns are in fact the non coding regions!

[@mavzai9800]

7:51 Nope

[@geetamahar9940]

Listen carefully ....thats exactly what he said...he is very clear abt what he teach..

[@sarveshamrute568]

Thank you so much sir...😊

[@شهابجمال-غ7ه]

you are great

[@sudeepbiswas6309]

by which the introns are made of??? where it differs from the exons thats why they cant code for translation....???

[@venomart4768]

Sudeep Biswas they basically not going to b translated into a protein. examples of introns are tRNA and rRNA

[@slimanelamia3225]

Thank you so much sur.

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You are the best!!!!!

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Thanx ak

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thank youuuuu

[@ChristlBolongaita]

4:35 Screenshot!

[@crickethub8708]

Great sir

[@goldenboy886]

Thanks

[@tpatnight]

2:06 screenshot

[@anawbs9]

Perfect

[@ChristianKekula]

I have a topic to discuss in class, this is the topic post transcription modifications

[@vikkramvenkatesan8656]

Hello sir is that possible to attach your notes in comment section

[@naomimacharia5609]

Thankyou...

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i wish i were this dude 😚 ALL THESE WOMEN GIVING HIM the thumbs up 🥰 👍

[@dsg003]

Great!!

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Why do I have to complicated stuff like this in high school? 💀 thx for explaining

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[@Indianintrovert]

Basics♥️

[@mazurutazviwana1757]

good

[@AKLECTURES]

Mazuru Tazviwana Thanks!

[@blockbyblock4078]

no doubt he is great at teaching but why does he pronounce "Process" the way he does it ? It's weird ;)

[@GeneticsLessons]

because he is originally from Russia as far as I know.

[@blockbyblock4078]

@@GeneticsLessons Oh! I didn't know that. Makes sense now

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Isn't is amazing how humans have the cognitive ability to learn how humans (and other organic beings) work lol.

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