Preventing Alzheimer’s Disease Using Groundbreaking Diagnostics | Gillian Coughlan

Preventing Alzheimer’s Disease Using Groundbreaking Diagnostics | Gillian Coughlan | TEDxVienna

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Күн бұрын

Alzheimer’s disease is the leading cause of death in over 50-year olds. However, we lack adequate means of diagnosing Alzheimer’s in its early stages, before neuropathological changes have brought on the clinical symptoms. Big data generated using a novel gaming app, together with sensitive and specific diagnostic tests, has helped us to detect subtle yet profound cognitive changes in those at risk for Alzheimer’s disease. This approach holds the promise of detecting dementia early, distinguishing between different dementia types and as a result, providing more personalised treatment options. Gillian Coughlan completed a Bachelor’s in Psychology (Hons) (2009-2013) and a Masters in Clinical Psychology at Trinity College Dublin (2013-2014). She became fascinated with cognitive neuroscience during her studies of cognitive ageing at Trinity Institute of Neuroscience (2014-2016). Gillian then went on to work as a visiting researcher at the Psychology Department of the University of Cambridge (2016) until she started a PhD at Norwich Medical School in UEA (July 2016) under the supervision of Prof Michael Hornberger. She currently investigates spatial navigation as a novel diagnostic marker for preclinical Alzheimer’s disease. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

Пікірлер: 33

@sleepsmartsmashstress740 3 жыл бұрын

The third step for public to take is to push the policy makers to allocate more funds to dementia and aging research given that rates of cancers and heart disease are dropping and there is less need to allocate funds for cancer and coronary artery research although hypertension research must proceed faster than before.

@melt2947 2 жыл бұрын

Books by Prof Dale Breneson, including “Ending Alzeimer’s” discussing reversing it as well. It’s been effective in his patients. I hope this helps someone 🙏

@sophiepauz4266 4 жыл бұрын

Well done Gillian 👏

@sleepsmartsmashstress740 3 жыл бұрын

Computer based testing of visuospatial testing to detect early AD is being developed at Univ of Manitoba in Canada as well. It is very rewarding. I was able to observe that in my mother who got diagnosed with A. D. Even early diagnosis would only delay the progression and death which might take place from another condition but in then end dementia would remain incurable as they are the end stage of brain growth

@kaylenedawnbuteaufitnessbu2282 Жыл бұрын

I'm writing a graphic memoir of how I used my health and fitness knowledge to stop my mother with mild dementia from forgetting me, and it worked. I tricked her off caffeine, then no prescription meds, forced her/tricked her/incentivized her to drink water, kept her away from high fructose corn syrup and other poison, because they made her mean and delusional, and kept her away from gluten. Funny thing is decades ago Dr. Oz said Zocor was causing memory loss and then my mother parroted that to everyone, but later on when she said it to a nurse practitioner during his assessment of a MMSE, he said she was delusional for saying that and this nursing home that I had to fight in probate court for 2 months to get my mother out, used it as a way to imprison her in a lockdown unit.

@suzanneyoung1729 2 ай бұрын

Hello, how can we find someone who can diagnose this aspect of AD risk??

@antonioruotolo6014 4 жыл бұрын

Innovative way to detect alzeimer. Congratulations

@riyavashishtha5228 2 жыл бұрын

CAC Brain Relaxant Churna This herbal churna is prepared from herb Atmagupta (Mucuna pruriens). The herb normalizes the nerve cell functions and supports brain function. It provides effective results in Alzheimer disease as it maintains the overall performance of the nervous system.

@AMindInOverdrive Жыл бұрын

6:40 - It's true about Jeans being a risk factor. I started wearing stretchy pants and my brain activity improved significantly! . . 🙂 just a silly joke to lighten the mood ;-)

@niecek.6473 3 жыл бұрын

Very interesting, it seems it we don’t use it, we lose it. Maybe more seniors should be playing games like this (navigation) eating less sugar in their diet. Eat real foods and Add a little fasting to gain autophagy? 🤔

@mflance7197 3 жыл бұрын

Caretakers at the end time has me shook . Help me tell me .

@kettymanno7256 4 жыл бұрын

They all explain dementia but very little specific ways to combat it.

@hannahholford2250 4 жыл бұрын

yeah i agree

@dotsgrey 3 жыл бұрын

Dementia (not AD-related) is a result of ageing, from the death of cells and subsequent shrinking of the cerebral cortex. There is emerging evidence that yoga is associated with a reduction in this shrinkage. The potential mechanisms for this could be the activation of brain regions involved in attention and emotion regulation. This activation would then help 'grow' new connections - so the rationale is that the more neuronal connections we have, the longer it will take for them to die. Like building muscles to slow atrophy, it takes regular practice across many years (8 years in this study). So, that's potentially one way you could slow the natural progression of ageing. The same rationale applies to learning new things (language, instrument), going new places, playing team sports, doing puzzles, etc... Sources: Afonso et al. (2017). Greater Cortical Thickness in Elderly Female Yoga Practitioners. Frontiers in Ageing Neuroscience, 9, 201 Gothe et al. (2018). Differences in brain structure and function among yoga practitioners and controls. Frontiers in integrative neuroscience, 12, 26.