Practice Problem: Retrosynthesis of an Alcohol

[@armantab3487]

Thank you so much. This was the first problem I actually got.

[@MrTanmoyHacker]

Please sir, make more videos on retrosynthetic analysis... Because your style, I mean how teach is so unique & awesome & students can easily understood that. So I kindly request you to make more videos (may be on problems or theory) on this kind of analysis..🙏

[@wrestpinpeace]

A few months later, and now, you've become Chewbacca to me. The ultimate secret to doing the Kessel Run in that many Parsecs, is a Wookiee for a copilot. Thanks pal, -Han Solo

[@annieregan4940]

This is probably a stupid question but my professors throw the phrase 'work-up' around a lot and I don't think I've ever heard it defined - does 'acidic workup' just mean that you're carrying out the reaction in an acidic solvent? Thank you!

[@ProfessorDaveExplains]

No it's a great question! Teachers always do that in lecture and neglect to realize that without having done much lab work, it's really hard to understand. Workup is when you quench the reaction when it's finished. So you do a reaction, like say a Grignard, and you're supposed to get an alcohol, but actually you are getting an oxyanion. You have OMgBr on the substrate. Then let's say all the Grignard reagents have reacted. Acidic workup is when you toss in some dilute acid like ammonium chloride, all the oxyanions get protonated in an instant to give the alcohol product, and the reaction is complete, no more chemistry will happen given the introduction of water to solution. That's how we do chemistry, but we never learn that stuff in lecture!

[@nehasathe2159]

Sir your videos are helping for my exam .. very nice videos.

[@THEaIexaIvarez]

wow thank you so much you are awesome

[@myway58]

what if the alcohol is 3rd order and we start with an isopropyl halide?

[@ucdiaries8064]

you are solving easy questions only.take more examples and explain