Protein Folding Mechanism

[@Shannu_1903]

I just love the fact that u did everything precisely and did not miss the important stuff...but yet saving time....thank you so much!

[@hussainbiology]

thanks for appreciation..Glad it helps

[@Mohit-px4do]

Excellent presentation..to the point no deviation..its fast nd accurate...it saves me a lot of time during my pg preparation for biochemistry..thank u

[@hussainbiology]

Thanks bro for the appreciation...... Keep supporting and Sharing to others...

[@mithakhantanoli1076]

@@hussainbiology hmm

[@vibzzlab]

THANK YOU SO MUCH. This really helped me save time in biochemistry for my NEET PG preparation

[@Ahmadkhan-bq2hc]

Great sir mashallh. At the moment preparing IIT JAM , yr videos are really helpful. Thanks a lot

[@hussainbiology]

thanks for appreciation...Glad to know that it helps ✌️

[@innate-videos]

Great vid! Presentations don't get much clearer than this!

[@hussainbiology]

thanks for appreciation Sir

[@studybuddies9252]

Oh god ..i dont have words to thank u sir... May Allah subhanwatala bless u and give u the mightest rewards for putting so much efforts and then providing the content for free..

[@studybuddies9252]

Moreever u being from Kashmir is such a inspiration...

[@tumnekahakaise221]

Very well explained. I am proud of your work it seems.. Amazing! Subscribed right away!

[@hussainbiology]

Thanks Manyata for appreciation...... Glad to know that it helps

[@apurvakmr]

Beta sheets have several beta strands with inter strand H bond. At minimum level, beta strands are a secondary structure

[@aamir122a]

Well presented, understood the protein folding ( at least at a basic level ) in one go.

[@hussainbiology]

Thanks for appreciation

[@galapagosworm3813]

Concise and Precise. Well Done.

[@hussainbiology]

Thanks buddy for appreciation....Keep sharing and supporting

[@directedbyanam]

Great Video. Very detailed with what was most important from these processes!

[@hussainbiology]

thanks for appreciation..Glad it helps ✌️

[@varshamk575]

Seriously Sir👍its just awsum way of explaining da things...takes no tym to feed in mind. Beautifully way of presenting through diagram by making it colourfull & neat. Eye catching👌handwriting n diagram. Am going to suggest frndz to for dis channel. Thank you🙏

[@hussainbiology]

thanks Varsha for appreciation..Glad to know that it helps..... Keep sharing and supporting ✌️✌️

[@shakilmuhammad4947]

beautiful accent, very soothing to hear

[@hussainbiology]

Thanks for appreciation...Glad to know that it helps.

[@shivangiarya7222]

Excellent presentation...its help me a lot 🙏🙏🙏🎉.

[@hussainbiology]

Glad to hear that

[@seethal9625]

Crisp and clear ❤ thank you so much ❤️

[@priyanshisharma2172]

All video Just awesome for quick understanding ❤❤😊

[@hussainbiology]

thanks for appreciation..Glad it helps..

[@shirse9331]

Ohh sir...thank you...sir I have a request..can you please make the lecture video on the topic of ""Thermodynamics of protein folding""

[@rimshakhan2672]

Wonderful work sir. It helped me in my presentation

[@hussainbiology]

thanks for appreciation..Glad it helps ✌️

[@meenaramalingam8874]

I took notes from your explanation and diagram only !! Thank you !

[@hussainbiology]

Thanks Meena for appreciation..... Really Glad to know that it helps,.,...

[@meenaramalingam4073]

@@hussainbiology My Pleasure ! Keep doing great!

[@hussainbiology]

Thanks Meena.... I need this kind of support ..Keep sharing and supporting

[@meenaramalingam4073]

@@hussainbiology Always for sure!

[@drsasmitadash6300]

Impressive .Subscribed right away

[@hussainbiology]

thanks for appreciation..Glad it helps..

[@varunnaidu9410]

Example for primary secondary tertiary and quaternary protein should have Been told

[@ramchandrasuthar2848]

Great analysis

[@aakifahaslam4623]

So well explained

[@hussainbiology]

thanks for appreciation..Glad it helps ✌️

[@RehanAli-ju2xn]

Very very very informative

[@Vladimir_protein]

I liked this video , thanks 👍

[@hussainbiology]

thanks for appreciation..Glad it helps....✌️

[@ryd5632]

Thank you!! Finally I understand it.

[@hussainbiology]

Thanks for appreciation......it is so amazing to see that my work is helping....

[@priyakshinath635]

Thank you for ds video.. Its good n easy to undrstand.. N also easy to prepare

[@hussainbiology]

Thanks Priyakshi for appreciation....Glad to know that it helps

[@priyakshinath635]

@@hussainbiology thank you sir

[@georgejoseph1430]

awesome job man! keep it up!

[@hussainbiology]

Thanks George for appreciation..Glad to know that it helps.

[@sonasunil5607]

Great job sir 👌

[@hussainbiology]

thanks for appreciation

[@tuna8014]

Thank you,sir🙏

[@michaeleisenberg7867]

Dear Dr. Hussain, Another superb video! Thank you. Have scientists tried to predict how a polypeptide will fold? Does the technology exist for a scientist to build de novo a functioning protein or enzyme?

[@hussainbiology]

Thanks for appreciation...Yes the technology exits

[@avicennawater]

The real question is really how does the polypeptides know it’s path to final shape in less than milliseconds let alone knowing what does the cell need to make such protein

[@michaeleisenberg7867]

@@avicennawater My guess is if you connected the same peptides in the same order they would fold the same way every time. It is because of the acid and base charges at each end of the individual amino acids, and the R groups. I think quantum mechanics and thermodynamics attempts to explain the mechanism of atomic interactions such as folding. It happens super fast. If you believe in evolution those proteins would not be here, nor you or I, if they did not fold into a functioning protein. Polypeptides evolved thru trial and error. The ones that folded into useful proteins were selected to stay. The duds were not promoted. Also chaperone proteins evolved (the same way) to help some proteins fold correctly. Not all proteins need the help of chaperones. Usually, if a protein folds incorrectly it is ubiquitinated and sent to the garbage heap (the proteasomes).

[@rakshitatambe8627]

Thank you sir very nicely explained 🤗

[@hussainbiology]

thanks for appreciation

[@TheeBotany]

Excellent. Thank you

[@Alchemist_171]

Are hydrophobic effects necessary for stability of a protein or is it just H-bonding? Particularly asking because I came across such question and I answered H-bond. Wondering if I was right.

[@rimplekour3882]

Well done sir

[@hussainbiology]

✌️🙏

[@srividyaamirishetty5724]

Super to easily understood

[@hussainbiology]

thanks for appreciation..Glad to know that it helps

[@asnanaval]

Is there any videos of molten globule state of protein

[@hussainbiology]

Not yet... Asna

[@wafaawardah3264]

Oh wow. Amazing video. Thank you very much.

[@hussainbiology]

Thanks Wafaa For appreciation......It really makes me happy when i get comments like that.... 😊

Thank Mr. Hussain

[@hussainbiology]

my pleasure

[@nifatjan7458]

Vry helpful......thnx a lot sir

[@hussainbiology]

you are welcome...

[@nasibakhontillaboeva5752]

thank yooou so much,now everything is clear to me!🤗

[@hussainbiology]

thanks for appreciation..Glad it helps ✌️

[@sportsadda006]

Thanku so much 🤗🤗

[@georgelacey4816]

Very complicated process explained simply.

[@hussainbiology]

Thanks Lacey for appreciation.........

[@luljetegecaj8195]

Nicely explained..thanks so much!! :)

[@hussainbiology]

Thanks for appreciation....Glad to know that it helps

[@dr.sayyediliyas1199]

Thank you so much

[@hussainbiology]

Thanks doc for appreciation

[@hussainbiology]

Thanks doc for appreciation

[@excitegamer5084]

hope so my lecture of tomorrow will be good❤️🥹

[@dr.doha_harby]

Wow👌👌

[@hussainbiology]

Thanks Doha for appreciation... Keep sharing and supporting 😊

[@hananerose8669]

Hi can I ask you what mines a floded three dimensional region of a protein that forms the basic unit of tertiary structure

[@verybad746]

Great job, love the accent :D

[@hussainbiology]

Thanks dear,,,,, glad to know that you love the accent......

[@samanthajoanamariemallari968]

Whoah! Thank you🥺 this is very informative ❤️

[@hussainbiology]

thanks for appreciation

[@ashutoshdwivedi3472]

Superb.

[@hussainbiology]

thanks for appreciation

[@beinghuman4457]

What will happen if hydrophobic region is kept on outer surface instead of hydrophilic part of protein?

[@madoaj653]

Do u have any website to uppload your pictures?

[@hussainbiology]

No sir

[@hananerose8669]

Hi what mines a floded three dimensional region of a protein that forms the basic unit of tertiary structure

[@hussainbiology]

unable to understand ur question ??

[@hananerose8669]

@@hussainbiology i found it its domain

[@hussainbiology]

@@hananerose8669 okay great...

[@prashantj50]

Thanks

[@kaipabingwit3276]

THANKS MATE!

[@hussainbiology]

U are welcome Buddy...Keep supporting

[@KomalKumari-jw6lz]

Which bonding involves in target proteins interacting with chaperones?

[@rahinadalvi8787]

Do fibrous protein exist in quaternary structure conformation or only globular proteins. And if yes den how polar and non polar separation occurs?

[@apurvakmr]

They do. Best example us the triple helical arrangement of collagen

[@kaayy6]

Omg thank you so much 😭 ! Now i have ideas how to discuss my part in our reporting😭😭

[@hussainbiology]

thanks for appreciation...Glad to know that it helps ✌️

[@KenJackson_US]

Are chaperone proteins universal? That is, do they help any protein fold correctly? Or is there one unique chaperone per problematic protein?

[@zohalalemi4322]

thank you so so so much! a real life saver!

[@hussainbiology]

Thanks Zohal for appreciation...Glad to know that it helps

[@ramelakoumrouyan4664]

Nice lecture! Are there any exceptions in the boy where 2ndary structure proteins are functional? (2ndary is when the bonds like disulfide and others form no?)

[@hussainbiology]

Hi Ramela , first of all thanks for appreciation........Now talking about proteins,,,,, I think Apolipoprotein E found to play crucial role in Alzheimer's disease has got functional secondary structure in the form of linear Alpha helices. ( still i am not 100% sure ). Thanks again

[@hussainbiology]

Also watch this video also kzbin.info/www/bejne/Zoepd2pjfN6LZpI

[@chaus0808]

Nice video.....keep it up!!!

[@hussainbiology]

Thanks bro.....Keep supporting

[@saadathsbiology9871]

Ur the best man keep it up

[@hussainbiology]

Thanks brother for appreciation

[@muhdhasni3682]

I think for B sheets, the hydrogen bonding is presence in interchain right ?

[@hussainbiology]

There will always be intra interactions..... Like intramolecular hydrogen bonds between beta sheets..... If you say interchain , that means two different molecule ( chains) form hydrogen bonds but in Beta sheets we always have same molecule and we will always form intramolecular hydrogen bonds.

[@avicennawater]

How do amino acids or cell in the process of forming fold to get to the ultimate final shape that cell needed to perform certain function ? I am alluding to the protein folding problem

[@फोकसलीफे]

Nice

[@hussainbiology]

Thanks for appreciation...

[@farispawan8756]

Excellent

[@hussainbiology]

thanks for appreciation

[@tahirtantary7438]

Informative

[@hussainbiology]

Thanks Tahir for appreciation....Glad to know that it helps

[@christianjoshuabanayat202]

why does the protein dont fold sometimes?

[@MotoDocADV]

How is this effected by Deuterium

[@alyssum1426]

What is parsley?

[@drsasmitadash6300]

Impressive

[@hussainbiology]

thanks

[@Sanp_bee]

👍👍👍👍👍nice

[@hussainbiology]

Thanks bro.....

[@mohd.saleembhat5658]

Nice ppt keep it up.......

[@hussainbiology]

Thanks Saleem.....

[@jyotidubey4890]

Thank you🥺💖

[@hussainbiology]

You’re welcome 😊

[@KARTAVYA_KR]

I think beta-pleated protein have intermolecular H bonding, by the way nicely presentated.

[@hussainbiology]

Yes....I have only stated intramolecular. BTW thanks for informing what is missing here.

[@ronaldvidal8036]

Nice.

[@kuldeepsinghshekhawat1389]

Thanx nice explenation of this topic sir but sir esko hindi m explanation dalo na sir plz

[@pharmacistalaa7079]

when the next vedio I want it, please...

[@kanicasharma1105]

Sir can we write this process under lipidation??....

[@hussainbiology]

Kanica U can't ,write this for Lipidation...... Lipidation is different process

[@kanicasharma1105]

@@hussainbiology thanks sir.... Btw ur videos are really very helpful....

[@hussainbiology]

@@kanicasharma1105 Thanks KANICA , it really inspires me when i get to know that my work helps,,,,Thanks,,,,Keep sharing and supporting

[@ohmnanon222]

New subscriber

[@pyrrho314]

I did like it.

[@hussainbiology]

thanks

[@ramchandrasuthar2848]

Very nice SIR

[@hussainbiology]

thanks dear

[@lazysuzy32598]

do beta sheets have intra or inter molecular h-bonding please answer

[@hussainbiology]

intermolecular

[@neelujain6807]

Can you plz make vedio in hindi

[@YeomraX]

long live india

[@edthoreum7625]

same professor as shomu's biology?

[@hussainbiology]

Yes , like him but i try to make short videos.

[@edobenu]

nice

[@hussainbiology]

Thanks Edoardo....

[@satyamdounde1351]

Ty sir

[@hussainbiology]

welcome

[@gayatribehera4075]

all are zoology biology students

[@raginiborkotoky1473]

7:17 what did he say ?

[@hussainbiology]

Proteases launch the attack on Protein , to get away with the protein,.... apologies for my weird pronunciation..... and my speed

[@raginiborkotoky1473]

@@hussainbiology Thankyou. This video was very helpful.

[@aratimaurya8464]

👌

[@hussainbiology]

Thanks for appreciation

[@ibrahimansari6753]

Please pronounced occurs correct

[@qn5595]

👍

[@hussainbiology]

🙏

[@saramalik5440]

Are u a Kashmiri, prolly from Kupwara

[@hussainbiology]

Yes Kashmiri ( no Bla)

[@saramalik5440]

Yes cud make it from your accent

[@saramalik5440]

I studied from st Joseph’s there

[@Abhisheksingh-di1pz]

Bhai tu muh se paan nikalkrr padha, gutka paan baad m kha lio, ya tu birthly totala h...

[@hussainbiology]

Birthyly he totla hai bhai.... Kya kare

[@Lightbulb909]

Polding

[@riyasharma6050]

Thank you so much

[@hussainbiology]

most welcome

[@karcicegi5366]

Thanks

[@hussainbiology]

you are welcome....Andrea Keep sharing and supporting

[@tahirtantary7438]

Nice