Purine nucleotide synthesis- AMP and GMP

[@binijajayakumar298]

What to say sir. Unlike your presentation. In our college- days our teachers don't explain like this. From this I learn a lot. Thank you sir. God bless you

[@Zagarex]

So much love for Dr Rajesh Jambhulkar, From Nigeria....... I love your lectures Sir....

[@DrChandrua999]

this is one of the chapter where our muggingup talent should be used very well..

[@Reeltonic360]

Entire biochem😢

[@Akshay88-21]

​@@Reeltonic360mera bhi exam he 2 din se mug up ker raha hy😂

[@Reeltonic360]

@@Akshay88-21 me to give up karke sirf previous year question paper PE aagyi😂

[@Akshay88-21]

@@Reeltonic360 😆haha nahi mera abhi 10 baje paper hen ek bar revison nahi Kiya to kuch nahi likh pavunga structure sab mix up ho jayenga

[@Reeltonic360]

@@Akshay88-21 All the best yaaar, hope wahi aaye jo tum padhe ho😂

[@Rinchatt]

sir you the only one who inspire me and make interest in biochemistry. your approach is very nice.

[@srilakshmiravindran4432]

Very true🤩🤩

[@arnabbandyopadhyay4551]

💓💓

[@sayanmisra5842]

Thank you so much sir Before this, I could never remember this pathway. But after seeing this video I can very easily do so now. Thank you sir once again for making things so simplified & easy.

[@khushiarora8865]

Sir I was about to leave this subject... scrolling you tube for free videos...you are boon to medicos....you are planting saplings like me . The first year students strong foundation....make more interesting biochemistry videos sir....tysm sir👍

[@sakshiagrawal5770]

Are these lectures enough for biochemistry nucleotide metabolism plzzzz reply🙏

[@madhurirampalli3492]

I found interest in biochemistry only bcoz of u sir.Thank u so much for the video

[@manjusheeba3961]

Sir thanks, during these lock down its very help full From kerala

[@komalrajpoot2419]

Best teacher of biochemistry😍love from Pakistan

[@soniapain7784]

Loved the magic in the middle... Where you waved your hand and all the short forms of the intermediates appeared 😂

[@SrotaSamal]

Again thanks for this type of method use which is a simplest way to remember

[@drmannysuccess1024]

you are genius to remember all the names

[@srilakshmiravindran4432]

Iam really thankful to God becoz i got ur channel thank u soooo much for making biochemistry interesting from a nightmare😍🤩🤩 god bless u sir 😍😍 ur each and every word is precious....❤❤❤

[@deepikapriyadarshini4140]

Thanks sir for taking efforts to make the concept clear and building up our interest and make it easy for us to study biochemistry without any hindrance 🙏👍 the way you teach in details is student friendly to grasp 😊👍

[@SrotaSamal]

Thank you very much sir for helping me to understand this chapter by a wonderful lecture and easiest way to understand 💫

[@farwajahangir6904]

Thank u so much sr for such a nice explanation..From Pakistan

[@khushikumawat367]

Sir I'm also a student of MUSH ....GMC ambajogai Maharashtra .... Well done sir ....your channel is the one of the best tutorial chennal on KZbin....I really enjoy your videos on different topics ....they are not only short tutorial but also knowledgeable 👍👍👍👍

[@kidsjourney6269]

kzbin.info/aero/PLNjEiJWqU7ft7XN42E6hhMKzmpc4woawF

[@nareshkumawat9096]

Ha

[@JJ-sv9jb]

Beautifully explained..hats off to you 👏

[@74.santhoshkumar.m80]

You teaching so nice and valuable

[@dhruvpatel4774]

Thank you so much sir... For making biochemistry interesting.. 🙌

[@sumeethsreeramoju1092]

Sir thank you very much 🙏🙏 Iam going to pass my exams only because of your classes. once again thank u so much sir

[@adaritridev5362]

Sir in naming of purine it should be anti-clockwise sir but u said as a clockwise and u named in anti-clockwise sir but sir u videos r very excellent very helpful for fast revisions

[@violason811]

See description

[@somanathkittur5416]

Correct

[@king.sports1707]

Purine 1st ring Anti clockwise And Purine 2nd ring clockwise

[@sanjaygodara3612]

Thanx a lot sir This is very helpful for our university exam which will be conducted after lockdown 😇

[@swastiknag9220]

Same here

[@abdulkadarhakim4206]

Super ... fabulous explanation... understood ths at once...keep up the good work sir..

[@kidsjourney6269]

kzbin.info/aero/PLNjEiJWqU7ft7XN42E6hhMKzmpc4woawF

[@vinaypatil9181]

👌👌👌sir, very useful, I will pass biochem bcoz of u.

[@wearepwians9877]

Thank you very much sir. Sir please continue giving us such amazing lectures sir, you are making mbbs life little soft ❤

[@ankushrathi1710]

Thankyou sir for providing free knowledge

[@tejesmundhe4643]

Sir you teach very good I like your all videos which are very usefull

[@Rinchatt]

sir i am a first year student now. so sir can you add some extra topics like cancer,nutrition,bioinformatics etc? it is my humble request to you sir.

[@kidsjourney6269]

kzbin.info/aero/PLNjEiJWqU7ft7XN42E6hhMKzmpc4woawF

[@VBJyoti-qr9iy]

You are such a gem, thanku so much sir god bless you😊😇

[@debasmitde8801]

It is indeed a tough but underrated subject.

[@fakru1409]

Ur helping me a lot sir.......❣️👍🏻

[@Kaur_2343]

😯😯😯thnks a million sir🙏🙏🙏this topic is vry difficult to remembr all the stps bt u made it vry easy to remembr.....🙏🙏🙏🙏

[@parthadas4313]

Memorising power hands off sir 🙏🏻🙏🏻🙏🏻🙏🏻

[@najeebahmad9740]

Thank u Sir i was waiting for this topic ...☺

[@sanjoyrudrapal2344]

Sir your videos are too good.

[@dr.jangamtharun7449]

Super uncle ... Tq for this wonderful lectures

[@bidyutpatra9211]

Awesome explanation sir......Thank you sir🙏🙏🙏

[@michaelshekoni6095]

Thank you so much, sir, God bless you!

[@suryacs3050]

Very helpful...well explained...thank you sir 🙏

[@priyagoyal9686]

Purine numbered in anti-clockwise direction

[@hunteroTube]

God bless you Dr.

[@sumitpokhrel3625]

0:28 I GUESSS WE SHOULD NUMBER IT IN A ANTI CLOCKWISE DIRECTION ????????????

[@Oktofalldown]

Thnk uu sirr u teach really well

[@mannannohria3079]

Beautiful lecture sir thank you ❤️❤️

[@adnanfaiz3875]

Do we need to remember each and every step or can we just say from 5-phosphoribosylamine to IMP is a nine step process requiring Gly, Glu, Asp and a couple of ATPs? Edit:Thanks for this video

[@Rajesh_Jambhulkar]

Write whatever you recollect at the time of exam Bcoz it is very difficult pathway to remember Do not forget headings Site, steps, regulation, energetic etc

[@zeeshan3577]

Sir sources of atoms in purine ring .. Lipponcott mein numbering different ki hue hai... Plz Explain. 1 Carbon is glutamine not Aspartate

[@indiankpopper4759]

@@zeeshan3577 Lippincott has numbered the purine ring according to the order in which the atoms have been added during _de novo_ synthesis. If you refer to figure 22.3 (of the 7th south asian edition), you can see the purine ring being numbered according to this video.

[@zeeshan3577]

@@indiankpopper4759 Thanks

[@DrRahulsenn]

सबका मालिक ekhi है Jambulkar Sir in Bioc❤️🙌

[@Rajesh_Jambhulkar]

Sabka Malik 1@ साईबाबा

[@anwarhusain811]

Very good explanation sir

[@radhakrishnanravichandran534]

Awesome explanation sir...tq sir...

[@USA.donkey847]

Sir Great vry great person 👏👏👏👏🙏🙏👍👍👍👍

[@smitpatel5921]

Sir thanks for the support to us

[@reetikamedhi2486]

THANK YOU SO MUCH SIR 😇

[@nareshkumawat9096]

Ha

[@tejesmundhe4643]

Sir I want some more case studies on corresponding topics

[@Tannyyyyyyyyyyy]

Thank you so much Sir 🙏

[@piyzim]

Is this a part of mbbs syllabus

[@vasumathim8682]

Thank u very much sir. Ur class is very easy to understand. 🙏

[@numankhan4027]

Thank u sir and love form Pakistan

[@chiemerieenebe4346]

You didn't mention the enzyme in the 8th rxn sir

[@akashkalita5905]

Shouldn't the last step involving nucleotide reductase have NTP as substrate instead of NDP?

[@د.محمدبهجت]

thank you, it makes it easy, thank you.

[@sandeepchoudhary7855]

Explanation 🔥🔥🔥🔥

[@kwizeraprosper8437]

Thank you so much Dr

[@yes_stretch_no_stress]

Thank you very much sir😇

[@manjaykumarsingh1751]

Best nice 👌. thanks sir

[@khadijawaheed1353]

Well explained 👍

[@arthikamiriyala1319]

In vasudevan they have mentioned that 1st step i.e,step 0 (where PRPP is synthesized) will not be included in de novo synthesis it will be a preparatory or preliminary step but here u r saying as 11 steps by including that step 0 ?????

[@biplobahmed8782]

Sir In step 7 carboxylation reaction with help of the Biotin need ATP. Then It will be Total 6 steps that need ATP. You said 5 Steps. Which will be right?

[@chingarirao3352]

Shouldn't it be glutamine (Gln) rather than glutamate(Glu) in the second step...formation of PRamine

[@antaraghosh5616]

Thank you sir😄

[@shahbaz9231]

Sir do we really need to remember all the steps for synthesis? is such question asked in exam?

[@Rajesh_Jambhulkar]

There are different types of paper setter. Such questions should not be asked in exam. Clinical significance should be preferred over chemistry part

[@shahbaz9231]

Biochemistry by Dr Rajesh Jambhulkar Alright Sir. Thank You.

[@nidaiqbal4359]

Thanku sr, it is easy now

[@Popmemes-w1d]

mind bloooowing

[@suhanan735]

Is this is the denovo pathway

[@kxrosheart9613]

Does purine biosynthesis is an energy intensive pathway as compared to pyrimidine biosynthesis?

[@brunaaquino5996]

Perfect!

[@vidushichandra9757]

Sir, for salvage pathway of purine nucleotide, do we need to write denovo syn as well?

[@Rajesh_Jambhulkar]

No need

[@musizforu4081]

hi vidushi did you wrote DR. rajesh sir lectures in notes?

[@tejasvisakhamuri1380]

Thanks you so much 🙏

[@Sakti-i8m]

Ribose 5 phosphate converted into phosphoribosyl pyrophasphate with help of ribosephosphatepyrophosphate kinase enzyme.

[@khizu2k]

thank you,so much sir

[@prateekpanda4224]

The purines are named in anticlockwise diretion not clock wise

[@Rajesh_Jambhulkar]

Yes👍

[@prateekpanda4224]

@@Rajesh_Jambhulkar but you are doing good job 👌

[@mulagalakshmicharitha6029]

Sir u said at the beginning that to number purine in clockwise direction...bt in video it seems like u started in anti clockwise direction...pls clarify this to me.. I'm a bit confused

[@Rajesh_Jambhulkar]

Correction is there -anticlockwise direction

[@mulagalakshmicharitha6029]

@@Rajesh_Jambhulkar thank you

[@bisandas6212]

Sir please upload salvage pathway video

[@mishtikundu4832]

Purines ki no. Anticlockwise hoti h u said clockwise

[@arjunb2504]

Sir 8s the first step i mean the syn of prpp isn't known as preparatory step (and is known as step 0)

[@dilawaix2709]

excellent sir

[@tahiransari3917]

Very helpful sir

[@fakru1409]

Sir I want ur hand written notes ...of biochemistry..🙏🏻

[@Soumya-gl4db]

Sir , how synthetic nucleotides are used as drugs?

[@MomentsUntold]

Thnk u Sir really helpful.

[@sereshkasoni1001]

Sir ye naam kese yaad kre

[@tvengatesantvengatesan5516]

Sir can you put lecture on inosine monophosphate dehydrogenase, please

[@mlt2waqarahmad20]

Great sir

[@lekshmischandran3295]

Sir do we need to remember all the steps?

[@pratheekgmenon7163]

Super trick sir

[@aditipatnaik2832]

sir I could not see the inhibitors of purine synthesis after 6-mercaptopurine...could you please write it hear in the comments

[@kidsjourney6269]

kzbin.info/aero/PLNjEiJWqU7ft7XN42E6hhMKzmpc4woawF

[@sakshiagrawal5770]

Can anyone tell me ,that are these 4 lectures enough for nucleotide metabolism ,plzzzz any one

[@SatyamKumar-ms9yv]

16:21 8:02

[@mbbsknowledge7066]

Awesome !

[@umangchaudhari7234]

Sir salvage pathway ka video chahiye plzz

[@asgharbughio6462]

Sir genetics k liye satyanarayan biochemistry parhain ???

[@Rajesh_Jambhulkar]

Read Harper if possible, Satyanarayana is also ok

[@asgharbughio6462]

@@Rajesh_Jambhulkar thanks sir