Fatty Acid Synthesis

  Рет қаралды 384,454

Dirty Medicine

Dirty Medicine

5 жыл бұрын

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

Пікірлер: 148
@ezikeadaobi
@ezikeadaobi 4 жыл бұрын
Biotin also serves as a coenzyme for the rate limiting enzyme; ACC(Acetyl-CoA Carboxylase). Great video👌.
@cuttingedgetechsongsmovies9662
@cuttingedgetechsongsmovies9662 11 ай бұрын
Teach me
@Dmhiz
@Dmhiz 4 ай бұрын
💯
@michaelsrowland
@michaelsrowland 2 ай бұрын
What is a rate limiting enzyme?
@frameshift_mutation
@frameshift_mutation 2 ай бұрын
@@michaelsrowland The slowest enzyme in the pathway
@clarissabethmore1711
@clarissabethmore1711 4 жыл бұрын
I think this video is by far THE most simplified version of fatty acid synthesis. Thank you sooooooooooo much!!!
@jessydecastro4686
@jessydecastro4686 4 ай бұрын
!!!
@nurulaliahrizal
@nurulaliahrizal 4 жыл бұрын
Thank you very much! I love the tip you shared about memorizing the rate-limiting enzyme. fatty ACC-id synthesis A-Acetyl C-CoA C-Carboxylase
@lana89001
@lana89001 4 жыл бұрын
This is gonna sound weird...but your voice makes me become so much more focused. Thank you for the video!
@harishsha1346
@harishsha1346 2 жыл бұрын
It's not weird I felt the same too..
@khadijah3343
@khadijah3343 3 жыл бұрын
Your videos are so amazing! Hours of lectures that I've barely understood makes sense completely :))
@leobarca678
@leobarca678 4 жыл бұрын
You are one of the few people that are so great at explaining such heavy stuff. Thank you so much, your videos are very helpful.
@argumentumadbaculum
@argumentumadbaculum 5 жыл бұрын
All your biochemistry videos are pure gold. Thanks a lot.
@maxbilo6191
@maxbilo6191 3 жыл бұрын
14:50 Citrate to Palmitate 17:10 Summary Slide of the net equation 17:45. Final Slide
@lisagonzalez2902
@lisagonzalez2902 3 жыл бұрын
Once more, an amazing video. It's even better because you have a lot of repetition so it helps for information to sink in.
@WhiteCoatPending
@WhiteCoatPending 3 жыл бұрын
your videos are always clear, concise and so helpful You are very much appreciated!
@priyam1550
@priyam1550 3 жыл бұрын
Thank you for making these painful topics easy to understand!
@duai7090
@duai7090 4 жыл бұрын
I can’t describe how much you made my life easier. My prof made things quite complicated to understand. Thank you 🙌🏼💛
@CathyMiscala
@CathyMiscala 4 жыл бұрын
You just earned a subscriber. Great job explaining this. Thanks!
@eturley7533
@eturley7533 Жыл бұрын
THANK YOU! This helped so much. I was wasting hours trying to learn this, but you made it so easy.
@alvinscharles498
@alvinscharles498 2 ай бұрын
Linolenic acid = the first "n" is third counting backwards (Omega 3) Linoleic acid = the first "n" is sixth counting backwards (Omega 6)
@anamariem8715
@anamariem8715 3 жыл бұрын
Oh WOW that is by far the best explanation of this topic . I don’t think I will have fun any where else studying biochemistry . Thanks a lot for the help.
@brandofett017
@brandofett017 3 жыл бұрын
Your voice and humor reminds me a lot of the channel Casually Explained. Love the videos!
@catfish7257
@catfish7257 3 жыл бұрын
I'm really having trouble to understand fatty acid synthesis explained by my lecturer, surprisingly when you explain it, it wasnt that hard!
@Jord40
@Jord40 4 жыл бұрын
Greatest of all time
@rhymez3606
@rhymez3606 4 жыл бұрын
Your channel help me allot in Biochemistry,now things became smooth
@thevegandragon4676
@thevegandragon4676 4 жыл бұрын
Brilliant video and explanation! Thank you soo much!
@user-po4cu7rb5z
@user-po4cu7rb5z 4 ай бұрын
I LOVE DIRTY BIOCHEM LIKE NOTHING ELSE IN MEDICAL STUDIES! DIRTY MED IS THE ONE THING WHICH WAS BEST EVER SOURCE WHICH MUST HAVE GIVEN ME SO MANY POINTS IN MY STEP 1❤
@anouded
@anouded 4 жыл бұрын
Your videos are GREAT :)) Many respect from Jordan
@yarenparlak1210
@yarenparlak1210 Жыл бұрын
This is the first time I've watched this channel but it won't be the last. English is not my main language but i understand more clearly than my lesson.
@ThatViolistKatie
@ThatViolistKatie 3 жыл бұрын
Even though this is for med students, this is awesome for MCAT studying too! It’s more than you need to know but I love to think about the big picture not just memorizing things.
@felipesolares
@felipesolares 2 жыл бұрын
Is there any way to watch the videos in order? The KZbin playlist doesn't put them in order and it's a bit confusing. Thank you for such amazing content. You are a life saver.
@yourwellbeing95
@yourwellbeing95 4 жыл бұрын
Countless thankx for sharing your knowledge..
@Salam_1965
@Salam_1965 4 жыл бұрын
Excellent video and outstanding teacher
@iabdullah4126
@iabdullah4126 2 жыл бұрын
man you are the real GOAT
@medicousa141
@medicousa141 2 жыл бұрын
This is pure gold
@sililly1379
@sililly1379 5 жыл бұрын
Thank you so much.
@vimalfestus8398
@vimalfestus8398 3 жыл бұрын
Today I binge watched all of ur videos🙌🙌
@mercifulserventurdu1753
@mercifulserventurdu1753 3 жыл бұрын
Wowww man you are just amazing, i have watched so many videos, but i stopped at yours, you explained so well and in an easy way 🌺👏 hat off 🎩
@naginakhan1ify
@naginakhan1ify 3 жыл бұрын
This isn't Dirty Medicine but Shining Medicine.. love the explanation. Thanks
@user-pk5mk9hi2m
@user-pk5mk9hi2m 5 ай бұрын
The citrate shuttle is like that of the malate shuttle where oxaloacetate should first be converted to malate, which can come out of mitochondria and then get reconverted to oxaloacetate for gluconeogenesis.
@ananyasharma172
@ananyasharma172 Жыл бұрын
you're effortless
@sherykhan3722
@sherykhan3722 2 ай бұрын
Really helpful ! develop understanding and concept you really explain it in simplest way
@giraybozkaya1377
@giraybozkaya1377 3 жыл бұрын
Thank you for the informative video. I noticed a mistake in the example of polyansaturated fatty acid. I remember that the double bonds between carbon atoms should be spaced at three carbon intervals, but the double bonds in the example are not spaced. Maybe you may think to change the example.
@kehalilmengistie3462
@kehalilmengistie3462 4 жыл бұрын
Thank you.
@kayallen7603
@kayallen7603 2 ай бұрын
The name of this process is gluconeogenesis . Your body does this to remove excess sugar/starch (they're the same thing) out of your bloodstream because the excess is TOXIC hyperglycemia. but too little is also deadly hypoglycemia.
@DrKat45
@DrKat45 23 күн бұрын
Excellent ❤,thank you.
@ND-zj2xe
@ND-zj2xe 3 ай бұрын
I’m so proud of my body that it remembers how all these processes work so perfectly … I would have never done that well by myself 😅
@hama297
@hama297 Жыл бұрын
Great vidoe great explanation,you don’t know how much you helped me thanks alottt
@udennaebii1585
@udennaebii1585 2 жыл бұрын
Glad I watched this one . Thanks Dirty.
@lucindadewaal9511
@lucindadewaal9511 4 жыл бұрын
THANK YOU
@derricknarhsormenah9383
@derricknarhsormenah9383 2 жыл бұрын
Great lecture! Thank you Bro
@nimraaslam7715
@nimraaslam7715 3 жыл бұрын
You are the best!
@tamunotonyeedward2544
@tamunotonyeedward2544 2 ай бұрын
Thank you so much sir. Your video said it all. ❤
@juaquannadavis9168
@juaquannadavis9168 Жыл бұрын
Well done.
@monika246
@monika246 4 жыл бұрын
Huge respect🙏
@Jumanajum_
@Jumanajum_ 2 жыл бұрын
you saved my life thanks
@emmanuelmwale5719
@emmanuelmwale5719 2 ай бұрын
You are the best
@derogatory.
@derogatory. Жыл бұрын
A true legend.
@jojoo98alth33
@jojoo98alth33 3 жыл бұрын
thank you you save my grades
@hassanalikhan5523
@hassanalikhan5523 2 жыл бұрын
Good explanation
@fgnsdfnbnd
@fgnsdfnbnd 3 жыл бұрын
EPA means 20 carbons and DHA means 22 carbons. A grass fed cow makes more omega 3 FA's than a grain fed cow (grain fed makes more omega 6 versus grass fed) BUT a pinky size slice of salmon has equal amounts of omega 3 as 8 pounds of grass fed beef.
@muneebtakesmedicine
@muneebtakesmedicine Жыл бұрын
accha
@TheUnXplainer
@TheUnXplainer 3 жыл бұрын
Thanks!
@mohammedfuadalusifiy7734
@mohammedfuadalusifiy7734 Жыл бұрын
Thank you so much 💓
@Mohamed.AbdelNasser.
@Mohamed.AbdelNasser. 6 ай бұрын
thanks
@salwaalmargny4685
@salwaalmargny4685 9 ай бұрын
Thank you so much
@JoshDanielGuitar
@JoshDanielGuitar 3 жыл бұрын
Don't forget that an important cofactor of Acetyl CoA Carboxylase is biotin (vitamin B7)
@dinayounis6473
@dinayounis6473 2 жыл бұрын
great video❤❤❤thank you
@DrPilot23
@DrPilot23 3 жыл бұрын
"guys an galls" thank a million sir
@rosemarka9639
@rosemarka9639 2 жыл бұрын
Amaaaazing,thank U so much ❤️❤️❤️❤️❤️
@manalhu1262
@manalhu1262 4 жыл бұрын
THANK U
@aliiraq9655
@aliiraq9655 3 жыл бұрын
Awesome ..
@user-ur9dk1mo3o
@user-ur9dk1mo3o 3 ай бұрын
Please turn on the Translation
@azuratriesnewstuff
@azuratriesnewstuff Жыл бұрын
You're a legend
@loveleenp.7311
@loveleenp.7311 4 жыл бұрын
This video was so helpful!! Thanks so much!
@agh6452
@agh6452 4 жыл бұрын
Omeg 3 I recommended everyday for my patients
@samjardavid6160
@samjardavid6160 Жыл бұрын
Penjelasannya keren banget...
@medicallifewithjohn8343
@medicallifewithjohn8343 4 жыл бұрын
Awesome
@kemigishamichelle5263
@kemigishamichelle5263 2 жыл бұрын
Wonderful video....🍓🍒
@shonyagura8508
@shonyagura8508 3 жыл бұрын
Most fats in the body come from fats in food and not from glucose which is mainly converted to glycogen by insulin and stored in the liver and muscles. After exhausting the synthesis of glycogen, then excess glucose is converted to protein or fats depending in the body's needs
@strongDr
@strongDr Жыл бұрын
Lol 😆
@michaelsrowland
@michaelsrowland Ай бұрын
The body converts excess carbohydrates into triaglycerols which are stored in the adipocytes
@michaelsrowland
@michaelsrowland Ай бұрын
Not in England where people eat 2000g of carbs a day and spend all day sitting at a computer or in their car or watching tv
@regminamuna1711
@regminamuna1711 3 жыл бұрын
Highly appreciate from Nepal🇳🇵
@strongDr
@strongDr Жыл бұрын
Keti Ko Keti Ko....
@Devil-kp2ek
@Devil-kp2ek Жыл бұрын
Please start recording vedios bcz it is very useful for us
@santhitapornklinthong9253
@santhitapornklinthong9253 Жыл бұрын
Your lecture is wonderful. I have some questions. How many ATP will happen from the fatty acid synthesis and how many cycle occur until the palmitic synthesis complete.
@kayallen7603
@kayallen7603 2 ай бұрын
w6 is what you usually get from terrestrial meat w3 come from oceanic fishes like sardine/mackerel/salmon "hence fish on Friday"
@Poiuytrew.Q
@Poiuytrew.Q 4 жыл бұрын
Maybe acetyl coA cant freely leave the mitochondria because if it did it would not as readily enter TCA.
@kimberjaneblake8736
@kimberjaneblake8736 4 жыл бұрын
thanks boo
@georgeklucsarjr1988
@georgeklucsarjr1988 2 жыл бұрын
Not a student, but like to learn. Is palmitate the only saturated fat made, or can there be other carbon length saturated fats made too? I know like butter and coconut oil, have several carbon length saturated fats ( I have no idea on how these are made though )
@chiahsuantsauo8375
@chiahsuantsauo8375 3 жыл бұрын
Wouldn’t the oxaloacetate be outside of the mitochondria which means it can’t take place in TCA? It’s not like the NADH generated in glycolysis or pyruvate metabolism that can utilize aspartate malate shuttle or glycerol phosphate shuttle to renter mitochondria
@santyguita
@santyguita 4 жыл бұрын
Great video, thanks.. This is why orange juice increases your triglycerides..
@siegmac3267
@siegmac3267 4 жыл бұрын
Because of citrate?
@sgill4833
@sgill4833 3 ай бұрын
Why does vinegar lower glucose response? Something to do with Acetyl Coa?
@princetandukar9290
@princetandukar9290 3 жыл бұрын
At 10:29, why cant the acetyl CoA straight go into Fatty acid synthesis in the cytoplasm after glycolysis? Why does it have to go through the citrate shuffle??
@Clevemac
@Clevemac 3 ай бұрын
"citrate is easy to remember, because in the presence of citrate, what the hell are you gonna do with it, other than convert it?" lmao
@inspiringvideosmsm5763
@inspiringvideosmsm5763 2 жыл бұрын
do we need to remember the equation of these pathways for step 1 ??
@karandeepkaur5211
@karandeepkaur5211 3 жыл бұрын
You made this topic so so so easy ...thank you alot💛
@redpilledbachelor7776
@redpilledbachelor7776 2 ай бұрын
What about Epinephrine? Woild it inhibit FA sythesis as well?
@daniellesan6466
@daniellesan6466 2 жыл бұрын
This great, but is not detalied enough for my exam in romania :(
@salam95159
@salam95159 4 жыл бұрын
May you activate Subtitles in English. Thanks
@giftchulu3523
@giftchulu3523 Жыл бұрын
Palmitate is a 16 carbon molecule
@mahakhan9762
@mahakhan9762 4 жыл бұрын
this video is amazing for mcat prep! thanks
@chisomchimezie
@chisomchimezie 3 жыл бұрын
Is it 6 molecules of water in the final reaction or 7?
@vinitdasilva
@vinitdasilva 3 жыл бұрын
Nice vid! 11:54 - the TCA cycle image out of the mitocondria confused me.. Isn't the TCA cycle an intramitocondrial cycle?
@salmanabashir1613
@salmanabashir1613 3 жыл бұрын
Vinitdasilva: from my little research oxaloacetate (impermeable to the mitochondrial membrane) can be converted into malate ( permeable) by the enzyme malate dehydrogenase. Then malate can either be moved into the mitochondria to take part in the TCA cycle or malate can be converted to pyruvate by a malic enzyme - this reaction can produce NADPH which we need in fatty acid chain synthesis. I hope that helped, I am just a first year med student soooo if I did make a mistake please let me know.
@cherryberry3850
@cherryberry3850 Жыл бұрын
Same question.
@bhumikachauhan333_
@bhumikachauhan333_ 2 жыл бұрын
🙌🙌💯
@Jumanajum_
@Jumanajum_ 2 жыл бұрын
dose always fatty acid synthesis start with glucose?
@alaaabdelsalamalamin5619
@alaaabdelsalamalamin5619 2 жыл бұрын
In each cycle we use 2 NADPH , I need 6 cycle to form the palmitate . That mean i use 12 NADPH , from where come the other 2 NADPH ??
@luna.kashyap1313
@luna.kashyap1313 4 жыл бұрын
I just love u
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