Respiration: Stage One - Glycolysis

[@jilareguy]

I don't usually write comments on KZbin, but I have to say, this is by far the best video I've seen so far on this topic and it has really helped me understand so much more. I hope you have more videos explaining the other stages of Cellular Respiration. Thank you very much!

[@MrPollockBiology]

Thanks for the kind words! Hopefully by now you've found my other respiration vids!

[@papermuffin3912]

This is one of the BEST explanation of glycolysis I've seen so far So concise and clear

[@michaelad3367]

SO MUCH BETTER THAN CRASH COURSE AND BOZEMAN SCIENCE!!! My teacher has always said fructose biphosphate, so would we get the mark in the exam for saying phosphorylated glucose?

[@hannahbayz]

thanks, i was struggling to understand the biochemistry of unit 4, until i viewed these videos

[@MrPollockBiology]

Thanks, glad they helped!

[@keshmeshnakhuutt9555]

This is amazing stuff! You've explained this extremely well. Thanks a lot and keep up the good work.

[@zhengmaggie8684]

You seriously make the best explainations. Thank you so much sir.

[@johntough7936]

when the 4 ADP molecules come to undergo phosphorolation, there are only 2xtriose phosphate molecules which each donate one phosphate... where do the 2 other phosphates come from to attach to the remaining 2xADP molecules...

[@aryanstanley3529]

After much digging, the answer appears to be that the two extra phosphates originate from H2PO4- (dihydrogen phosphate), which is readily available in the cytosol. The phosphates are first donated by H2PO4- to the 3 carbon molecule (at this stage, intermediates between triose phosphate and pyruvate), then removed by ADP later to form ATP. See diagram: upload.wikimedia.org/wikipedia/commons/a/a0/Glycolysis.svg In short, there are phosphate-donating molecules just floating around the cytoplasm, which are happy to give over their phosphate groups.

[@thetwinnies5970]

great video, just wanted a quick summary video before a test and was exactly what i needed :) thank you xx

[@kyleowens470]

Amazing video , thankyou

[@naturesgirl3078]

3:23 ohhhh. Now I understand. Thanks for the video 👍👍

[@nicoleserrano1055]

I finally get this! Thank youuuu!

[@kalumthomson5638]

Will the examiners accept phosphorylated glucose even though it's actually fructose bisphosphate? Thanks!

[@georgiav9507]

Really really helpful, thanks! Your videos are great! :)

[@aryanstanley3529]

Mr Pollock, where DO the other two phosphates come from? I'm not studying AQA Biology and am studying/revising respiration for other reasons, but the appearance of two more phosphate groups not bound to the 3-carbon molecules is confusing me and most descriptions seem to gloss over this. (Great video, btw)

[@whatthehell359]

in itttttttt

[@samparnham9276]

Aryan Stanley.... the hydrolysis of ATP, creating ADP Pi - there are only 2 ATP molecules, so the extra 2 phosphates come from the reaction of 2ATP turning into 2ADP Pi

[@aryanstanley3529]

Thanks for the replies, but I don't feel like anyone has satisfactorily answered the question yet. At the end of glycolysis, 4 x ATPs are formed, meaning 4 x phosphates are required. I know that 2 x phosphates came from the triose phosphate molecules, which in turn came from the 2 x ATP molecules that were "used" at the beginning. So that still leaves the question as to where the OTHER two phosphates came from.

[@aryanstanley3529]

For others reading this question, I think I finally stumbled across the answer: The two extra phosphates originate from H2PO4- (dihydrogen phosphate), which is readily available in the cytosol. The phosphates are first donated by H2PO4- to the 3 carbon molecule (at this stage, intermediates between triose phosphate and pyruvate), then removed by ADP later to form ATP. See diagram: upload.wikimedia.org/wikipedia/commons/a/a0/Glycolysis.svg

[@suhail1200]

U get 2H+ ions too right ?

[@isabellemay9071]

Thank you so much!!

[@heatherlivesey9452]

Really useful for Edexcel SNAB topic 7 too! Thank you!

[@MasterNinja786]

why is glucose unreactive (sorry if its a stupid question)

[@THEGIRLKISSERPROJECT]

this is so so helpful thank you

[@mariam.a941]

OMG u just make it looks like the easiest thing ever and u really really helped me. THANK YOU

[@whatthehell359]

why 4 ATP come in?

[@vinesybaby]

Great video, The only slightly confusing aspect, when ATP is invested in stage one, it almost sounds as if you have said that two ATP have being used. Your animation makes it look like that. Aside from that, really helped. Thank you.

[@ElderBeanzHLH]

+ash cartwright Its because 2 ATP's are used. It is to give the glucose 2 phosphates to the glucose so it can become reactive, and therefore when it splits, a phosphate group is on both of the 'splitted glucose' which is TP

[@ridevo613]

for the exam I have classroom notes about glucose being converted first into glucose 6 phosphate then fructose 6 phosphate and then fructose 1,6-biphosphate. Do we need to know all this for exam or is it okay if we just say glucose is phosophorylated to become fructose 1,6-biphosphate?

[@majak.t.135]

4:33 All good till now ...But, 'dont worry about 2 extra phosphates and where they came from ' got me saying : Waaaaat??? How should I not worry if another two are thre and I have no clue How they got there ? ....Anyway...willl continue watching ...

[@Playlistlit]

well done.

[@mohammadaniyal]

Thank you sir

[@mikaosola8009]

My guy Mr Pollock

[@slimqt9224]

LEGEND

[@بريطانيابالعربي-ش3ب]

Simple and easy to understand Subscribe ❤

[@runa3625]

my head hurtie mr pollock :(

[@hnltte3696]

hello thx

[@jrester8331]

tenk yow

[@callumbryant4331]

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