Ribosomes: structure and function

Ribosomes are cell organelles with a peculiar structure and function. In this video, will talk about many things ribosomes, especially their roles in protein production and the differences between the types of ribosomes.
We will cover the following:
00:00 Intro
00:34 Definition of ribosomes
02:25 Structure of ribosomes
06:08 Protein synthesis
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[@user-ir4re8th9u]

Everybody needs a teacher like you mann❤

[@JoaosLab]

Oh thank you so much! So kind of you! ❤

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Not joking i had terrible misconceptions, doubts and quaries about rrnas like it solved them all . i love your channel bcuz of this and youre now one of my 4 subscribers 🎉❤❤❤❤❤​@JoaosLab

[@swastikahore4583]

The video helps me a lot to have a clear concept about Ribosome . Thanks a lot.

[@JoaosLab]

You're very welcome! 😊

[@kelliknight1132]

Great information. Sometimes you need those extra pieces to put the whole puzzle together. My microbiology prof left a few holes and you filled them so i understand, now.

[@JoaosLab]

So happy to hear that! I am glad these videos are helping you learn these topics. We have a lot of fun producing them. ❤

[@potatochip190]

I think it's good enough he wanted to explain them, my prof didn't even bother explaining 🤣

[@nimraakhann]

Probably the best explanation of ribosome! Thank u sir!

[@JoaosLab]

Oh thank you so much, Nimra! 😊🙌

[@msnewnewgirl]

I was looking all around to get the basic defintion of the function and everyone was using terms I didnt understand!but you using simple words "It helps the cell make the proteins it needs" helped so much. Thank you God bless you.

[@JoaosLab]

Your comment made my day! Thank you so much! This is why we make these videos. ❤😊

[@mijinyawabashir5280]

What a great presentation!

[@arinomacaroni6316]

Hadn't heard about these! Thank you! 😄

[@JoaosLab]

You're very welcome! These little guys deserve some attention.. and a video. 😊

[@laolu1098]

Man thanks have been looking for a material to simplify this for me bro you did well

[@JoaosLab]

So glad to hear this was helpful! 🙌

[@anjalidalai6825]

seriously sir your explanation is too good just cleared my doubts so easily... thank you sir

[@JoaosLab]

You are very welcome, Anjali! Stay tuned for the next ones that I will be publishing in the next weeks. 🙌

[@hridayasrivastava7879]

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[@JoaosLab]

Thank you! ❤🙌

[@jawairiazahid8864]

Both your animation and your speaking style is outstanding 👍. It is the best explanation of ribosomes.

[@JoaosLab]

Thank you so much for the kind words! It means a lot to me ❤

[@premellghjerhanne2804]

what a feel-good lecture. you made it easier for me to understand

[@JoaosLab]

So happy to read your comment! Thank you! ❤

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This is a very nice video. Enjoyed a lot! Thank you

[@JoaosLab]

Glad you enjoyed it, Nafisa! 😊

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[@JoaosLab]

Thank you for your kind words! Stay tuned for more videos! ❤

[@edwinkarunasena9180]

Detailed and well explained

[@JoaosLab]

Thank you! 😊

[@AmirTalipov]

Great explanation: simple and clear.

[@JoaosLab]

Thank you so much! ❤️

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Love Joaos energyyyyyy

[@JoaosLab]

Thank you! 😊❤

[@mariarahman2232]

This video deserves more views! Love from Bangladesh ❤️🇧🇩

[@JoaosLab]

Thank you so much, Maria! Welcome to the channel! ❤

[@kakajan8334]

I am so thankful sir this video made the concept so clear

[@JoaosLab]

You're very welcome!

[@dianhendrayanti7147]

nice video to learn complicated process! thank you

[@JoaosLab]

You are welcome, Dian! 😊

[@sejal5235]

Thanks for the best explainating

[@JoaosLab]

You are most welcome! ❤

[@shanayakhan4145]

Learning easy way for us sir thank full

[@pronoytripathy4047]

It's an excellent explanation...yes science is a fun becoz of u . thanks a ton!

[@JoaosLab]

This comment made my day. Thank you for the kind words! ❤

[@hibayahiya8013]

Wow! I was confused but everything’s clear! And the jokes are quite funny too and thanks for making science more interesting!!

[@JoaosLab]

Happy to hear that! Thank you for the kind words! 😊

[@ridhi4186]

I have a test on 70S and 80S Ribosomes in a few hours lol. Thanks for finally helping me understand what a ribosome even is :)))

[@JoaosLab]

Best of luck! 🙌

[@ridhi4186]

@@JoaosLab Thank you!!! I got full marks on the test :)))

[@mmm-vk2er]

Thani you for this video !

[@JoaosLab]

You are very welcome! 😊

[@Kaurharleen_42]

Thank you sir 🙏.. this video helps me alot 😇

[@JoaosLab]

You're very welcome! 🙌

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He is good, why don't people watch his videos. He deserves more than 100m subs.

[@JoaosLab]

Thank you so much for the kind words! I believe that in time, and with support like yours, people talking about and sharing the videos, this will help us build a larger community. 🙌

[@alikhorram6668]

that was really good and useful thanks alot

[@JoaosLab]

You're welcome! 🙌

[@gm_prince]

Thank you sir!❤ Watching from Bangladesh💖

[@JoaosLab]

You're very welcome! ❤

[@kalebasnake9127]

I love all of your video but when I was learning at school our textbook implied that ribosomes are made in the cytoplasm but the subunits (RNA& Protein) are produced in nucleolus and facilitated to the cytosol for assembly of ribosomes. What do you have to say on this?

[@adityasinha1921]

Helped a lot thanks

[@JoaosLab]

You're very welcome! ❤

[@user-rw2ne6hr3h]

Brilliant! And funny.

[@JoaosLab]

Thank you, Val! ❤

[@johnlamphier3515]

This is how teaching biology should be.bring it to life

[@JoaosLab]

That's exactly the goal! Thank you ❤

[@AndrewPick6]

Great video. I think it would be informative to include the fact that the anticodon on the tRNA (which binds to the mRNA codon) specifies which amino acid it will carry.

[@JoaosLab]

Thank so much, Andrew! That's a good point. I am planning to create a video in the future where I will cover that topic in more detail. So stay tuned!

[@khanhnhutranle4457]

Love the video🥰

[@JoaosLab]

Thank you! ❤

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[@JoaosLab]

Thank you! Science is indeed beautiful. ❤😊

[@aashkaurjosan_1]

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[@JoaosLab]

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[@JoaosLab]

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[@JoaosLab]

You're welcome! 😊

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[@JoaosLab]

You're very welcome! And thank you for the kind words! 😊

[@tamilboy5541]

this really helped me to learn. Thanks a million!!!!. And also I wanted to make such videos in my native language. So, can you please tell me which software did you use to create these videos?

[@JoaosLab]

So happy to hear that! You're very welcome. 😊 We use mainly AEs to animate these videos.

[@veronicacosta4237]

Muito bom seu vídeo! Ameiiiiii

[@JoaosLab]

Muito obrigado, Veronica! 🙏

[@khalilarsalani393]

Thanks a lot i got more information about ribosomes

[@JoaosLab]

You're welcome! 😊

[@ayeshasiddiqui7191]

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[@JoaosLab]

Thank you! 😊

[@giyuu4003]

Thank You

[@JoaosLab]

You're very welcome! 😊

[@KHUTSOPRECIOUSMLOTSHWA]

nice lecture..may i have other functions of ribosomes

[@Studyneet.]

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[@JoaosLab]

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[@JoaosLab]

You are very welcome! ❤

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Thank you for this video.

[@JoaosLab]

My pleasure!

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[@JoaosLab]

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[@JoaosLab]

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[@JoaosLab]

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[@JoaosLab]

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[@JoaosLab]

Glad you liked it! 🙌

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[@JoaosLab]

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How does the phone call at 5:25 work actually inside a cell?

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[@JoaosLab]

So happy to hear that! 😊

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[@JoaosLab]

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[@JoaosLab]

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[@JoaosLab]

So glad to hear! Welcome to the channel! ❤🙌

[@rukhsarahmadi2025]

Omg the way u teach is awsome can u be my prof fr

[@JoaosLab]

Thank you so much for the kind words! 😊❤

[@vijjalaxamikumari2516]

Sir why are prokaryotic are only one rrna

[@susanbenishaa3912]

How to calculate 70s 80s ribosome subunit

[@farzivardhan]

Can we call ribosomes cell organelles since we say organelles are not present in prokaryotic cells ? 2:35

[@JahidulIslam12184]

In our book, 70S ribosome has 3 rRNAs of 23S, 16S, 5S. And 80S ribosomes contain 80 types of proteins.

[@JoaosLab]

The numbers may vary depending on the book/reference you use. So use those that is recommended by your instructor. 😊

[@beautifulgurl5803]

❤

[@mdshahriaahmedshawon7631]

Sir, in some source, it's says, "The overall structure comprises a large 50S subunit, composed of 23S rRNA, 5S rRNA, and 28 ribosomal proteins, and a small 30S subunit composed of 16S rRNA and 20 ribosomal proteins." (www.ncbi.nlm.nih.gov/pmc/articles/PMC7546915/#:~:text=The%20overall%20structure%20comprises%20a,rRNA%20and%2020%20ribosomal%20proteins.) But in your video, you says that in 30S subunit there are 16S and 21 protein and in 50S subunit, there are 5S and 31 protein. So which information is correct? (I'm weak in English, so please try to understand my language)

[@JoaosLab]

Hi Shahria, This number might differ slightly between references. The ones I have used mentioned the numbers I listed in the video. For example, this one: www.shorturl.at/dpSU1 🙂

[@mdshahriaahmedshawon7631]

@@JoaosLab Thanks sir 🙂

[@user-vp4wh8co9d]

I like the accent 😎

[@heba1956]

aren't you the guy from kenhub???

[@JoaosLab]

Yes! I am one of the cofounders of Kenhub. This is my personal channel. Welcome! 😊

[@inhabitantofearth]

Where does the tRNA come from? And what happens to the mRNA after the protein is made, where does it go?

[@JoaosLab]

tRNA molecules are transcribed from specific genes in the nucleus, carry amino acids to the ribosomes, and participate in protein synthesis. mRNA molecules are transcribed from DNA and serve as templates for protein synthesis. Once the protein is made, the mRNA is degraded, and the ribosomes can be reused for further protein synthesis. I hope this helps answer your questions. 😊

[@koko-uk1rp]

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[@Musical_World69]

I think ribosome is not an organelle It's just a macromolecule which is found in cytosol

[@JoaosLab]

It's definitely debatable. Ribosomes are complex macromolecular structures found in the cytosol and attached to the endoplasmic reticulum. While they are essential for protein synthesis and are often referred to as organelles, they differ from traditional organelles as they are not membrane-bound. This information can also differ a lot between references. Some of the main references consider them non-membrane-bound organelles, others just macromolecules.

[@Valentino016]

I was confused about Ribosomes and I didnt want to read the text book so I came here

[@JoaosLab]

Welcome to the channel!

[@SasiKala-kr1vg]

You are explaining those while making joke its cool😊😊😂🤣

[@JoaosLab]

I am so glad you liked the humor! 😊 I love to laugh, so just wanted to bring that to the videos as well.

[@vivekshukla7007]

23s rna was missing

[@user-ni7ww9cn2t]

The ribosomes isn't organelles, because they aren't membrane bounded. As it is mentioned in Campbell chapter 7 edition 11

[@JoaosLab]

Organelles can be membrane-bound or they can also be non-membrane-bound, but they are still organelles. 😊

[@mimosveta]

I think of fishes, cause riba is fish in slavic languages..

[@cyriljanda253]

1/3 sugar, 1/3 spice and 1/3 everything nice...just kidding! 😀

[@JoaosLab]

Gotta love some powerpuff girls!! ❤

[@darkesthawk889]

Ribosomes are technically not an organelle since they do not have a double membrane, but can be considered a ‘non-membranous organelle’

[@JoaosLab]

Organelles can be membrane bound or non-membrane bound. Ribosomes are non-membrane bound organelles, but they are still organelles. 😊

[@khutejakhanum1127]

They r nt organelles bc they dnt ve membrane they r structures

[@JoaosLab]

Not all organelles are membrane-bound. 😊

[@mariamemad6]

Man how come you are so underrated 😭😭😭 great video btw, I am a first year medical school student and thanks to you my suffering with histology ended just now 🥹🤍🤍

[@JoaosLab]

Thank you, Mariam! That means so much to me. 😊 I am also glad these are useful to you in medical school. Stay tuned for more video coming out in the next weeks.