Electron transport chain

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Harvard Online

Harvard Online

6 жыл бұрын

From our free online course, “Cell Biology: Mitochondria”: www.edx.org/course/cell-biolo...
Harvard Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implications for mitochondrial disease inheritance.
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Пікірлер: 2 000
@HarvardOnline
@HarvardOnline 5 жыл бұрын
Learn more in our free online course, “Cell Biology: Mitochondria”: harvardx.link/pwnt
@letsbehonest4221
@letsbehonest4221 4 жыл бұрын
I am from Australia .. May i do this course .. and how hard is the exam. .I am not an educated person, I work as a Roadie (event set up for bands and other events) but would love an opportunity to learn some thing new.
@higherresolution4490
@higherresolution4490 3 жыл бұрын
Has the animator mistakenly shown Complex II as transmembrane instead of being part of the Citric Acid Cycle in the Matrix? I love the video. Just wondering if the mistake is on my part.
@SeaJay_Oceans
@SeaJay_Oceans 3 жыл бұрын
I would say that now, a key difference between biology and technology is stability at room temperature. You can turn off a computer and turn it on weeks later and it's still works. But you can't 'shut down' a living being, and restart them weeks later - their molecules break down and degrade, too fragile.
@geraldbamberger927
@geraldbamberger927 3 жыл бұрын
Outstanding work. Thank you for this magnificent legacy, Dr. Lue.
@100nirosta
@100nirosta 2 жыл бұрын
please remove the reality under the microscope. Show the real nature, not this fictional graphics.
@LavenderTheArj
@LavenderTheArj 4 жыл бұрын
I remember when I was studying biochemistry II in my bachelor's degree, desperately looking for a video on this on the night before the final exam, didn't find one and had to memorize it the old fashioned way, all I'm saying is that what you're doing is extremely valuable for a lot of students, best of luck.
@sortof3337
@sortof3337 4 жыл бұрын
Hello, I have a question for you. There is a news about a company called Solar foods, which apparently converts C02, h20 and electricity to make single celled proteins. I am a software engineer but very disturbed by the fact that I can't find anything about this. Wouldn't it be creating life out of soup or could the be just using microorganisms?
@PriyageethKS
@PriyageethKS 4 жыл бұрын
@@sortof3337 single-celled protein🙄
@Cazy243
@Cazy243 4 жыл бұрын
@@sortof3337 There's no such thing as a single celled protein. Proteins are macromolecules made of amino acids and they make up parts of cells, but they themselves aren't cells. Maybe you meant to say that they were designing a way to synthesize simple proteins?
@2bdocvarun
@2bdocvarun 4 жыл бұрын
Was thinking the same
@rajarshigupta6207
@rajarshigupta6207 3 жыл бұрын
There are single celled proteins which are being used by astronauts for their protein requirements. It is made by microbes like spirullina They have way more protein content than meat
4 жыл бұрын
Imagine a whole biochemistry book animated like this... I wish I'd be alive till then :'(
@vblaas246
@vblaas246 4 жыл бұрын
Not a whole book, but the ibook EO Wilson's Life on Earth comes very close. Same animators. More people should get to know of it. It is great.
@LouieAblett
@LouieAblett 4 жыл бұрын
@@vblaas246 thanks so much, I've got it now and installed itunes u so I can do all the assignments. I can't believe it's free
@vblaas246
@vblaas246 4 жыл бұрын
@@LouieAblett You're very welcome :) Check pdb101 (protein data base) if you're looking for more specific background information.
@vblaas246
@vblaas246 4 жыл бұрын
@Sakurako Hikari Yes, I'm thinking at the Cardboard Demo app by google by which you rotate objects (masks and vases) by rotating your head. Create the scene with mMaya plugin and use Unity to render the scene. Have been thinking about making a website for that, must be cheap though.
@kathrinat9824
@kathrinat9824 4 жыл бұрын
@@vblaas246 hey would you know any way to get it on android
@noelsrx376
@noelsrx376 3 жыл бұрын
This is physics, chemistry and biology combined in one! And I love it!!
@hugodaniel8975
@hugodaniel8975 3 жыл бұрын
I wish there were more black, women and lgbt in science
@Hexnilium
@Hexnilium 3 жыл бұрын
I would add computer science / engineering here as well. It's functioning as a molecular machine, and starting to work with information at a computational level.
@carmenmoldoveanu4897
@carmenmoldoveanu4897 3 жыл бұрын
@@hugodaniel8975 they have first to define themselves.
@gameslayer404
@gameslayer404 2 жыл бұрын
@@Hexnilium lies
@gameslayer404
@gameslayer404 2 жыл бұрын
@@jacky9575 Cause life is better then machines and stuff, and has absolutely no correlation to it.
@killianoshaughnessy1174
@killianoshaughnessy1174 4 жыл бұрын
I am amazed at the complexity of being alive.
@kxmode
@kxmode 2 жыл бұрын
(Psalms 139:1) "O Jehovah, you have searched through me, and you know me." (Psalms 139:14) "I praise you because in an awe-inspiring way I am wonderfully made. Your works are wonderful, I know this very well." 🙂
@dr.cheeze5382
@dr.cheeze5382 2 жыл бұрын
@@kxmode ok and? no really, do you seriously think quoeting some old book full of so many contradictions and compleatly ficticuous facts is going to make me belive in a being that doesn't need to even exist to explain the universe?
@MegaBlack077
@MegaBlack077 2 жыл бұрын
​@@dr.cheeze5382 is there a reason why the redox centers are perfectly aligned clusters of different atoms?
@Haven_city_civilian
@Haven_city_civilian 2 жыл бұрын
Me too.
@casualbird7671
@casualbird7671 2 жыл бұрын
@@MegaBlack077 yes, the ones that weren't didn't survive :>
@hasen_judi
@hasen_judi 4 жыл бұрын
"and this is why we have to breath oxygen" was a mind blowing moment for me.
@denislavvladimirov4977
@denislavvladimirov4977 4 жыл бұрын
it's mind blowing how God made it friend :) He is like that... : D
@javsw.1878
@javsw.1878 4 жыл бұрын
Denislav Vladimirov dont claim god for this, it’s evolution that made us this way
@hasen_judi
@hasen_judi 4 жыл бұрын
@@javsw.1878 Sure, whatever
@maryweprin
@maryweprin 4 жыл бұрын
Perhaps God and evolution are not different. Billy
@Verspassungsschutz
@Verspassungsschutz 4 жыл бұрын
@@maryweprin which god? Vishnu? Thor? Ra?
@nickmagrick7702
@nickmagrick7702 4 жыл бұрын
the visual explanation really helps a lot.
@hosoiarchives4858
@hosoiarchives4858 Жыл бұрын
0:29 inner mitochondrial membrane 0:47 key role is to separate protons, inner from outer protons 1:08 ATP synthase, makes ATP. Uses proton flow to work 2:24 Complexes 1, 3 and 4 pump protons out 2:49 complexes get energy from electrons 3:18 complex 1 uses NADH and reduces it
@pasqualethene
@pasqualethene 10 ай бұрын
Thanks. Bruh no replies
@Mala-tg1lg
@Mala-tg1lg 14 күн бұрын
Thanks
@lilyilyily323
@lilyilyily323 2 жыл бұрын
RIP prof lue, this video is just one of many thousands of wonderfully helpful, selfless things he contributed to the world during his too-short lifetime.
@aryansaeedi7618
@aryansaeedi7618 4 жыл бұрын
My god what a beautiful video. Very clear and well explained. I’m in love with this channel.
@SachinSharma-id9kd
@SachinSharma-id9kd 4 жыл бұрын
@arin saeedi HI DEAR!
@muhammadtayab1909
@muhammadtayab1909 3 жыл бұрын
You are nice
@muhammadtayab1909
@muhammadtayab1909 3 жыл бұрын
@@SachinSharma-id9kd f
@grantfryer407
@grantfryer407 2 жыл бұрын
why you say God?
@MarceloCostaoficial
@MarceloCostaoficial 2 жыл бұрын
@@grantfryer407 HOW CAN YOU NOT? If you can't see GODs desing on that you are blind
@Ronin777z
@Ronin777z 3 жыл бұрын
The animation was incredibly helpful in understanding the material. My mind tends to wander during lessons so the visual aspect was immensely helpful.
@yvonnemoreno8805
@yvonnemoreno8805 3 жыл бұрын
This is amazing. It puts all these concepts we're inundated with and makes it more clear. As a visual learner, I wish there were more animated videos like this!
@Roger-go6jc
@Roger-go6jc Жыл бұрын
This is just awesome. I'm 69 now and still doing paediatric nursing, but started my career in Pathology. I remember pawing through my Biochemistry text to sit exams and trying to memorise the Krebs Cycle, which is all part of this. But the process I did on a page that showed chemical energy utilised for cellular respiration has just blown right off the page. This visual takes me into a Mitochondria and starts to put the cycle into a visual sense. What a wonderful progression in knowledge we have. Now lets not forget who we are and what a beautiful planet we have.
@NewWesternFront
@NewWesternFront Жыл бұрын
who are we
@comamiday462
@comamiday462 2 ай бұрын
lol u may now at least something @@NewWesternFront
@lucachirico4183
@lucachirico4183 2 жыл бұрын
I watched this video 3 years ago for the First time, when I was studying biochemistry for the exam of the bacheloor degree. Now I've just re-watched it to review the topic at all for work, and it's gorgeous like ever. I think immagines and videos can teach better then thousand of a book's pages. Colours and animations are for me the best way to rember and put every feature in our brain.
@Lisargarza
@Lisargarza 2 жыл бұрын
Learned all this stuff in grad school 40 years ago, but it was more like a concept, a chemical formula written on a page. To see it spring to life as an animated video is astounding. Thanks for posting.
@prestonburton8504
@prestonburton8504 4 ай бұрын
i was simply struggling to get through it - and i hated it. but it was still something i wanted to learn later as it was a void. He found a way that i could visualize and understand it. This is teaching!
@divinephanes
@divinephanes 3 жыл бұрын
I remember seeing this in my first year bio class, it blew my mind when I first saw it and it still does. Thank you for this!
@andychow5509
@andychow5509 4 жыл бұрын
Wow. Amazing how much progress and knowledge we are starting to have access to. Never saw anything like this when I was growing up.
@makaylamoore8831
@makaylamoore8831 4 жыл бұрын
Such a great, clear explanation! Videos like this remind me why I love biology so much. Life is amazing.
@antoniodimaggio5658
@antoniodimaggio5658 4 жыл бұрын
i was about to write the same thing!
@kritikathakur5895
@kritikathakur5895 3 жыл бұрын
We want animations like this really. They helps us to have a deep insight in the topics. Thanks
@SoirEkim
@SoirEkim 4 жыл бұрын
I may not be fully aware of what it took to put this information together. Yet, I love learning in this way and the visuals are mesmerizing. Therefore I would willingly watch several days worth of videos like this. Excellent! Thank you.
@maryamfazal3180
@maryamfazal3180 2 жыл бұрын
No other video could convey the concept that this video has conveyed. Best video ever, I'll never forget ETC ever again.
@matthewmayorga2855
@matthewmayorga2855 5 жыл бұрын
This is the best visual explanation of the ETS I have seen on youtube
@mindyourbussines8698
@mindyourbussines8698 3 жыл бұрын
Enfermedad de transmisión sexual.
@mrkoelle
@mrkoelle 2 жыл бұрын
Agree
@Bananappleboy
@Bananappleboy 2 жыл бұрын
@@mindyourbussines8698 why
@mikethespike056
@mikethespike056 2 жыл бұрын
@@mindyourbussines8698 SIII JAJAJ
@umu-i-d2785
@umu-i-d2785 4 жыл бұрын
This happens a few Trillion times a second in our bodies. No big deal!
@mikkirefur
@mikkirefur 4 жыл бұрын
Nope, not for a loving intelligent creator - but people prefer to listen to the darkness of the enemy and deny the existence of the engineer of life. ridiculous.
@elbretto6062
@elbretto6062 4 жыл бұрын
@@mikkirefur what
@koaoi9172
@koaoi9172 4 жыл бұрын
@@mikkirefur how many shrooms did you ingest
@jtktomb8598
@jtktomb8598 4 жыл бұрын
@@mikkirefur u okay ? having visions ?
@jacobkudrowich
@jacobkudrowich 4 жыл бұрын
@@mikkirefur insane how you can see this and take it as proof of your god
@trainerbrock2428
@trainerbrock2428 2 жыл бұрын
Videos like this are the future of molecular biology education at all levels. Great video!!
@MrZooganopolos
@MrZooganopolos 3 жыл бұрын
That was a lovely and descriptive review! Thanks for taking the time to make such a great video!
@rolandoe.diazolivom.d.4777
@rolandoe.diazolivom.d.4777 4 жыл бұрын
Congratulations for this excellent video. Next up, please: The microscopic machinery of the outer mitochondrial membrane. This is the gatekeeper preventing a massive influx of H+ and other cations in the surrounding matrix from entering the inner mitochondrial matrix.
@jayski9410
@jayski9410 3 жыл бұрын
I wish we could have had visualizations like this back when I was a pre-med student in the 1970's. All we had were acronyms, arrows, and line drawings. The best analogy I can come up with is a wrist watch - in my day we could look at the watch face but just read about what made the hands go around; this animation is like opening up the back of the watch and finally seeing all the gears and springs in action.
@dielaughing73
@dielaughing73 2 жыл бұрын
I studied this stuff in the 90s and the technology had barely progressed. I am in awe at what has been achieved since then. This is very, very important work.
@michaelK.3272
@michaelK.3272 Жыл бұрын
This is one of the most informative videos I have ever seen. Excellent quality. Thank you!
@jadhavaniket100
@jadhavaniket100 2 жыл бұрын
I was searching for a perfect explanation for the ETC and couldn't find any. Came to KZbin and saw your video and was blown away. Thank you so much. It shows that it has taken immense efforts to create this amazing video. Thank you once again..
@igoralencar4817
@igoralencar4817 4 жыл бұрын
This is so beautiful. I've been looking at it for five hours.
@stephenarmiger8343
@stephenarmiger8343 2 жыл бұрын
Reading Brian Greene’s book, Until the End of Time. He does an admirable job explaining this. I appreciate this attempt to help us understand the situation in three dimensions!
@amira6405
@amira6405 Жыл бұрын
I just clicked on this video. 10 seconds in and I am welcomed by a voice I recognize. The voice of a fellow Jamaican (RIP to Robert Lue). It's so surreal how just a voice can connect you to someone and now to a video I am wholly excited to watch and learn from.
@audreya7543
@audreya7543 6 күн бұрын
This is easily the most clear-cut and visually useful aid I could find online to look at the ETC complexes 1-4. I can't thank you enough for this resource!
@iainmacdonald8379
@iainmacdonald8379 4 жыл бұрын
I'm reading The Vital Question by Nick Lane and this video really helped me to understand respiration, particularly redox. Fantastic book, by the way.
@peterschmidt1453
@peterschmidt1453 3 жыл бұрын
We can thank Drew Berry for pioneering the animation of this invisible world, his ability to visualise these subatomic processes has made these animations possible.
@AyeshMedic
@AyeshMedic 2 жыл бұрын
This was Amazing!!! The most distinct video of it's type. I was having so much trouble in ETC and here it is in such an easy way. Good Job.
@ectogamut
@ectogamut 4 жыл бұрын
5:19 The shark tooth ghosts show up, get their eyeballs, and leave.
@Biliana_Stanimirova
@Biliana_Stanimirova 4 жыл бұрын
I am not the only one thinking the same. The shark tooth ghost is my spirit animal! :D Its so little and cute
@COUNTERSTRICKGAME
@COUNTERSTRICKGAME 4 жыл бұрын
What 😂
@uzaysezen7319
@uzaysezen7319 4 жыл бұрын
nice one!!!!! :) :) :)
@benjaminfranklin5137
@benjaminfranklin5137 4 жыл бұрын
@@Biliana_Stanimirova don't get it
@blazednlovinit
@blazednlovinit 4 жыл бұрын
@@Biliana_Stanimirova * Pacman Will Remember This ( ? )
@fzka_
@fzka_ 4 жыл бұрын
This is such a good visual explanation. Thanks!
@lorrainecamilly7354
@lorrainecamilly7354 2 жыл бұрын
É um dos melhores vídeos sobre o assunto que eu vi, muito didático. Excelente!
@raplopez4258
@raplopez4258 2 жыл бұрын
What makes this video stand out is not just the breaks, but the respect for the student, BY GIVING US 5-30 SECOND BREAKS TO JUST RELAX THE BRAIN!!!! (*Cough to all you other science videos/teachers out there cough cough*)
@vedantbhardwaj7582
@vedantbhardwaj7582 4 ай бұрын
I'm a medical student at King's College London, and honestly this has helped me sooo much with actually being able to visualise how Oxidative Respiration actually occurs! Thanks!!!!!!!!
@prernakumari7273
@prernakumari7273 4 ай бұрын
Medical student also study botany..?
@vedantbhardwaj7582
@vedantbhardwaj7582 4 ай бұрын
@@prernakumari7273 this type of process is also what happens in human/animal cells, so it is something we cover in medical sciences.
@hridyansh-san5270
@hridyansh-san5270 2 күн бұрын
​@@prernakumari7273 why are you stupid? This happens in all eukaryotic cells containing mitochondria!!
@jesusmiguelalvarezfernande8761
@jesusmiguelalvarezfernande8761 2 жыл бұрын
Just the opposite of what happens during photosynthesis in chloroplasts. What a wonderful balance!
@NewWesternFront
@NewWesternFront Жыл бұрын
we are the plants. the plants are we. forward backward with the trees. vroom skeet skloom dbbdhfjskkdf
@evanquinn6092
@evanquinn6092 4 жыл бұрын
This was an amazing video, you didn’t skip info and make it confusing thank you
@user-gn3sy7mq6w
@user-gn3sy7mq6w 2 жыл бұрын
This is extremely helpful for me !!!!!!! Super grateful for the master piece that you produced !
@geofractal
@geofractal 4 жыл бұрын
This is incredibly amazing. It is also amazing that humans can figure this out -- very smart humans, that is.
@turquoisecoleman6006
@turquoisecoleman6006 4 жыл бұрын
Geo Fractal well it's more like 'The Apple doesn't fall far from the Tree ' . (of life) ... right ? if you get me .? 🤗
@larscp
@larscp 3 жыл бұрын
Compare to the nature, then we are still monkeys
@bili4591
@bili4591 2 жыл бұрын
That’s more amazing than the fact that human can figure this out. Its impossible to build this for any human this is the creation
@maxjurish2589
@maxjurish2589 Жыл бұрын
Very smart God, that is!
@brandon-pz2ye
@brandon-pz2ye Жыл бұрын
Can figure it out but also immediatly forget all of it when talking about profitable things like cancer, diabetes, heart disease.
@rachelchristiansen9218
@rachelchristiansen9218 4 жыл бұрын
I was literally feeling so screwed over my biochem exam because i could NOT grasp this concept. This was so clear and easily explained and I feel way more confident going into my test, and better yet it was INTERESTING and easy to continue to watch. Thanks!!
@XFz2nLDWo73x95
@XFz2nLDWo73x95 2 жыл бұрын
Did you pass? lol
@sunilnale
@sunilnale Жыл бұрын
@@XFz2nLDWo73x95 Hope So 🙃
@saysHotdogs
@saysHotdogs Жыл бұрын
@@sunilnale we still waiting
@user-pt8zt8ip3b
@user-pt8zt8ip3b 10 ай бұрын
Như trên 🤩
@abhinabachakraborty7207
@abhinabachakraborty7207 3 жыл бұрын
Dont have words to appreciate enough how beautifully this video has been made 🥰
@TommyTumma
@TommyTumma 4 ай бұрын
Professor Lue’s microbiology course at Harvard was really easy to understand. The hallmark of a great teacher. I recommend taking his full online class for free!
@judas611
@judas611 Ай бұрын
How do I find this course? Do you have a link?
@greggrobinson5116
@greggrobinson5116 2 жыл бұрын
Seeing this chemistry written out as reactions is impressive enough, but seeing it animated is just astonishing! And to think that this is going on effortlessly in every one of our cells all the time is downright religious.
@edehc
@edehc 2 жыл бұрын
INSANE IN THE MEMBRANE! AND ALL OF THIS IS HELD TOGETHER BY DIFFERENCES IN ELECTRICAL CHARGES? JUST WOW…
@myblueparadise5807
@myblueparadise5807 Жыл бұрын
This is the best animation I've seen so far....I just have no words to appreciate you❤
@letsgo4834
@letsgo4834 2 жыл бұрын
Beautiful. I wish I’d had this type of material from which to learn and review years ago.
@mingngyt
@mingngyt 4 жыл бұрын
This was beautiful. amazing music and lesson.
@saisasori1073
@saisasori1073 4 жыл бұрын
Yes Ming ning ding,ho chi new, ho Lee 🐮
@iwantafreetrial7611
@iwantafreetrial7611 4 жыл бұрын
@@saisasori1073 wtf
@chetan6984
@chetan6984 3 жыл бұрын
@@iwantafreetrial7611 ming ping chow pee lee✊🏼✊🏼
@PheedPhil
@PheedPhil 2 жыл бұрын
Great video. Haven't seen a better animation anywhere else. And very accurate too, with the exception of one small detail (which most text books also get wrong). FADH2 is not the electron donor to complex II, it is physically attached to the first protein of the complex (a flavoprotein). Succinate is the electron donor (CII is called succinate dehydrogenase) and CII oxidizes it to fumarate in the Krebs cycle, passing the electrons to it's FAD, and onward into the complex.
@vitoria96634
@vitoria96634 Жыл бұрын
It's amazing you have such knowledge :D glad to know!
@sunilnale
@sunilnale Жыл бұрын
@@vitoria96634 Do You Difference between NADPH and NADH. Similarly between FADH and FADH2. my textbook is Using them alternatively... 😑
@AnuragTarmaster
@AnuragTarmaster 8 ай бұрын
@@sunilnale Sorry this is 6 months late but to answer your question they are just two different electron carriers. For every NADH the electron transport chain can produce 2.5 ATP, whereas for every FADH2 the ETC can produce 1.5 ATP. Like @PheedPhil said, succinate dehydrogenase catalyzes the reduction of FAD whereas isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, and malate dehydrogenase catalyze the reduction of NAD+ in the citric acid cycle.
@sunilnale
@sunilnale 8 ай бұрын
@@AnuragTarmaster Thanks... I am Still Giving Same Exam... Thanks for Explaltion... Have a Good Day/ Night... ☺️
@BPLeroyLotusEvora
@BPLeroyLotusEvora 3 жыл бұрын
Absolutely fantastic educational video about the mechanisms of mitochondrial energy production!
@ngc-ho1xd
@ngc-ho1xd 4 жыл бұрын
Life is the ultimate Rube Goldberg machine, that in essence performs a task very similar to Maxwell's deamon. It's so beautiful!
@ffghjj9996
@ffghjj9996 4 жыл бұрын
ngc 4594 found paul davies youtube account
@lenn939
@lenn939 4 жыл бұрын
Nothing in humans violates the second law of thermodynamics.
@danteseluvathingal5292
@danteseluvathingal5292 5 жыл бұрын
That was amazing.thanku soo much
@sangitasharma4692
@sangitasharma4692 9 ай бұрын
This is one of the best animation video i have ever seen with such a great and clear explanation
@johnathanh9369
@johnathanh9369 2 жыл бұрын
I start off watching videos then I dig into the textbook so then I can imagine it. This allows me to memorize and understand it better.
@samp-w7439
@samp-w7439 2 жыл бұрын
The fact that this is constantly going on in our bodies is insane. The fact that people have somehow figured out all the details and intricacies of this tiny and complicated processes is on a whole other level!
@nikitasid4947
@nikitasid4947 4 жыл бұрын
That feeling when you read an offline paper book on Mitochondria and then KZbin recommends you this.
@blazednlovinit
@blazednlovinit 4 жыл бұрын
It's okay, youtube just enjoys listening to you breathe at night.
@Bman-1970
@Bman-1970 3 жыл бұрын
Your household appliances hooked into the internet may have suggested it.
@anushkapande2085
@anushkapande2085 2 жыл бұрын
@@blazednlovinit that sounds oddly threatening im terrified
@brucejohnson5786
@brucejohnson5786 3 жыл бұрын
Dude this just blew my mind. Thanks, it really clears things up
@JohnHillEU
@JohnHillEU Жыл бұрын
Very newly interested in biochemistry and it's amazing to see the similarity in the proton concentration gradient has with the mechanisms at play in silicon transistors!
@rodneywar
@rodneywar 4 жыл бұрын
Thank you for sharing this highly educational video.
@kirschkern8260
@kirschkern8260 4 жыл бұрын
Amazing, you tube is the biggest Libraru or best University/school. Sad they will block or bann it. They try to make it payable.
@snowwhite2038
@snowwhite2038 3 жыл бұрын
@@kirschkern8260 seriously....... Why don't they want poor people to get educated for free
@dickmorhead6165
@dickmorhead6165 4 жыл бұрын
I have my mother's eyes and my mother's mitochondria.
@peacenow42
@peacenow42 4 жыл бұрын
Moms share like that.
@rutvin8763
@rutvin8763 3 жыл бұрын
@Sumanoharam Jha "X has their mother's eyes" is a common expression. Ask before going on a pointless rant.
@rutvin8763
@rutvin8763 3 жыл бұрын
@Sumanoharam Jha Yes, it was; dumb comments need addressing.
@rthmjohn
@rthmjohn 4 жыл бұрын
Hands down, best video on the ETC on KZbin.
@JMYaden
@JMYaden Ай бұрын
These clever animations really make this whole fascinating process come alive. Thank you! I will take your free online course!
@writer24x7
@writer24x7 4 жыл бұрын
4:26 A small amount of energy is released? Energy in what form? How the complex harnesses this energy?
@kaukabbhatti1661
@kaukabbhatti1661 3 жыл бұрын
To be honest, this is the best animation I have seen on this subject.
@lenz5362
@lenz5362 3 жыл бұрын
fr fr
@amelalghwel
@amelalghwel Жыл бұрын
Thank you so much for this video! I'm studying Biochemistry II and this is the very first time I understand completely how electron transport chain works. Thank you very much for your efforts.
@aylinm5439
@aylinm5439 Жыл бұрын
I love how he stops occasionally, so the knowledge sinks in. Thank you so much, helped alot.
@fotoflo
@fotoflo 4 жыл бұрын
4:26 - "a small amount of energy is released each time an electron is passed between redux centers" -- in what form is the energy released and stored?
@switchthechannel6317
@switchthechannel6317 4 жыл бұрын
Complex 1?
@AlecPerkey
@AlecPerkey 4 жыл бұрын
as i understand, its a physical conformation change of the protein (depending on which point the electron currently is) which allows movement or "pumping" of the protons into the intermembrane space. So the energy is stored via in the pH (electrical) gradient difference on either side of the membrane. I don't think Randy's answer of 'photons' is right, the electron isn't changing energy states, its just moving along different atoms on a transmembrane protein ending up on the other side of the membrane, changing pH see en.wikipedia.org/wiki/Chemiosmosis#In_mitochondria and en.wikipedia.org/wiki/Oxidative_phosphorylation#Electron_and_proton_transfer_molecules
@marijnstollenga1601
@marijnstollenga1601 4 жыл бұрын
Basically in kinetic energy in the protein complex, that then somehow pumps protons to the other size of the membrane. The energy is then stored essentially in the higher electron potential between the membrane and is harnessed by allowing the electrons to flow and create ATP. ATP is the final power storage that is essentially used everywhere in the body.
@May4thbwithu
@May4thbwithu 4 жыл бұрын
Look up the photoelectric effect first demonstrated by Einstein I believe.
@goku21youtub
@goku21youtub 4 жыл бұрын
@@marijnstollenga1601 the right answer , people who try to solve this with physics will get nowhere, but ,its not really kinetic energy either the molecule gets reconfigured
@rcarmisin3465
@rcarmisin3465 4 жыл бұрын
I got so lost watching this video, it was 20 minutes later until i realized i was staring at the wall. lol :)
@tomorourke6301
@tomorourke6301 2 жыл бұрын
Since I've gotten Clean and Sober, this has become my all-time favorite video...feels like a Plato's mystery school subset....
@kalldr6355
@kalldr6355 2 жыл бұрын
Thank you so much for this, you're saving lives out here
@An0nim0u5
@An0nim0u5 5 жыл бұрын
Please can you guys make a video on Photosynthesis as well...???
@kirschkern8260
@kirschkern8260 4 жыл бұрын
Exyst somewhere for sure.
@abdulekimhuseen3971
@abdulekimhuseen3971 3 жыл бұрын
Please can you guys make a video photosynthesis as well.........?
@howtogaintime739
@howtogaintime739 4 жыл бұрын
What a beautiful little world, wish I could see it up close.
@turquoisecoleman6006
@turquoisecoleman6006 4 жыл бұрын
HowToGainTime Well you get to Experience it !! Which is even better . of course some would have to be done in Slow Mo !! 😜
@TheLoucM
@TheLoucM 4 жыл бұрын
Thats the weirdest part to me... because if you were to shrink enough too try too see it up close, you wouldnt see anything, because atoms and molecules are almost entirely empty and dont really emit or reflect photons at this scale (only emits photons when an electron loses energy). Add to that that we see by having photons reflecting on surfaces. We basically see our world only because of the scale at which we operate as an organism. In short, at this molecular scale, ''seeing'' means nothing. Animations like this is basically just like seeing the real thing for us hoomans, as its the only way for us to be able to interpret it and see it as something we can make sens of... if that makes sens ?
@rafiqshah2022
@rafiqshah2022 3 жыл бұрын
Become antman
@howtogaintime739
@howtogaintime739 3 жыл бұрын
@@rafiqshah2022 I dont want to become mediocrity
@Margo296
@Margo296 2 жыл бұрын
Finally I understood what the electron transport chain is! Thank you so much
@apothecurio
@apothecurio Жыл бұрын
The jump from atomic particles make a thing that is deemed as a system that sustains itself had always fascinated me and ,as a lowly layman, found it hard to actually find where I could find that info. This is the perfect start. Amazing.
@denisa.6793
@denisa.6793 4 жыл бұрын
oh my god, i praise the author, incredibly helpful
@mikkirefur
@mikkirefur 4 жыл бұрын
The author of course is the Lord God in heaven above. Clearly our current understanding of biology has proven life is designed.
@RetrogradeBeats
@RetrogradeBeats 4 жыл бұрын
Mikki Refur no
@pigeonlove
@pigeonlove 4 жыл бұрын
@@mikkirefur evolution, trial and error, chance mutations and adaptions, not gods
@peacenow42
@peacenow42 4 жыл бұрын
I praise everyone this is the most intellectually cognizant conversations ever on KZbin comments maybe.
@zhou_sei
@zhou_sei 4 жыл бұрын
@@mikkirefur that's not what i take away from it. actually, the more i learn, the less i believe in an invisible magic wand-waver in the sky.
@IzzytMe
@IzzytMe 2 жыл бұрын
So I can actually harness quantum energy in each cell of my body, simply by breathing oxygen and my teacher said I'm no good at physics. That can't be right!
@nikhatreena2461
@nikhatreena2461 3 жыл бұрын
Out of world work,,such a hard topic explained in a cool fashion,,kudos to your work and thank you so much 🔥🔥
@nsbd90now
@nsbd90now Жыл бұрын
I like biology and I really like modern animations of biological processes. Absolutely amazing! I subscribed.
@hanadiam8910
@hanadiam8910 4 жыл бұрын
(صنع الله الذي أتقن كل شيء) سبحان الله Thank you for this very informative video!
@rodschmidt8952
@rodschmidt8952 4 жыл бұрын
When the gradient is insufficient and the mitochondria no longer produce ATP, the cell can become starved of energy and -- become cancerous? Are not small amounts (~5%) of ATP always produced elsewhere in the cell by fermentation?
@jamesralston5293
@jamesralston5293 4 жыл бұрын
Death occurs
@demonking86420
@demonking86420 4 жыл бұрын
Depends on the organism. Some organisms aren't facultative anaerobes.
@kirschkern8260
@kirschkern8260 4 жыл бұрын
I also though on cancer. But maybe it shows other results or symptoms.
@kirschkern8260
@kirschkern8260 4 жыл бұрын
I heared omega 3 fat or faty acids are importsnt to kerp the Membrane strong. Anf the industrial fats in cookies are destroyinh the Membrane. Making the Metochondria "leaking" Protond. So it produce less Energy ir get useless at all.
@jamesralston5293
@jamesralston5293 4 жыл бұрын
@@kirschkern8260 it is now thought that this weakening of the membrane is the root cause of diabetes
@partypao
@partypao 4 жыл бұрын
Wow!! Now I've finally understand it!! Books can never explain a complex process as this!
@sinayasharabi8302
@sinayasharabi8302 Жыл бұрын
I have recently been obsessed with animations of this theme, they are simply fascinating.
@redemptivememelord6283
@redemptivememelord6283 3 жыл бұрын
For once I read it as "Electron transport chan" and I thought I'd meet a molecular biology waifu
@alessboo17
@alessboo17 3 жыл бұрын
HAAAHAHAHAHAHAH
@maxattacks25
@maxattacks25 Ай бұрын
You might’ve seen Cells at Work already, but this reminds me of that 😂
@catmom1322
@catmom1322 2 жыл бұрын
This is terrific! I wish we had had something like this when I was i n grad school, but I'm thinking some of this may have been discovered after I graduated. Either way, I'm loving this!
@semexambcma
@semexambcma 3 жыл бұрын
Just mind blowing. thanks you all of the team.
@BramMichaelson
@BramMichaelson 4 жыл бұрын
I think I've seen all this before when I got REALLY high.
@peacenow42
@peacenow42 4 жыл бұрын
When you go back there, maybe you bring some post-its and tag some of the molecules. To say you were there.
@ferid9k
@ferid9k 3 жыл бұрын
1:40 thats actually just a theory.We still dont know how atp synthase works
@servetbozdag2359
@servetbozdag2359 2 жыл бұрын
MaşaAllah Ferid. I heard that we just know one percent of the human body maybe less
@nithichotechongrungruang3778
@nithichotechongrungruang3778 4 жыл бұрын
Thank you, we're all very grateful of what you did.
@malorie1042
@malorie1042 3 жыл бұрын
Love these videos. So so so much easier to understand & learn.
@neigeepierrot4694
@neigeepierrot4694 4 жыл бұрын
Amazing this happens everyday
@goku21youtub
@goku21youtub 4 жыл бұрын
every nanosecond, trillions of times in just a single living being
@goku21youtub
@goku21youtub 4 жыл бұрын
@As It is physics= assembler chemistry/atomic and molecular level = c++ life = error doesnt compute
@mikkirefur
@mikkirefur 4 жыл бұрын
@As It is I would think, analogically speaking, both. low level super efficient machine language, and high level OO designs.
@mikkirefur
@mikkirefur 4 жыл бұрын
Thank God, literally, for that !
@Rek-55
@Rek-55 4 жыл бұрын
@As It is at old age there processes not ideal...
@oleksiyalkhazov9201
@oleksiyalkhazov9201 4 жыл бұрын
Science is the best mystery and greatest magic in the multiverse
@jerryo1228
@jerryo1228 Жыл бұрын
Excellent video, with very complex processes; explained clearly and easily to understand.
@sweetpea7270
@sweetpea7270 2 жыл бұрын
incredibly helpful, and great animations, THANK YOU SO MUCH
@xinchen3547
@xinchen3547 3 жыл бұрын
Respect to the masterpiece of the Creator, and the marvelous job of the makers of this video.
@cynthiaalbrecht3248
@cynthiaalbrecht3248 2 жыл бұрын
That is what leaps out at me, that this degree of complexity, not to mention the homochirality of the sugars and amino-acids, points to Creation by means of technology far more advanced than that employed by humans.
@leonardsipula1063
@leonardsipula1063 2 жыл бұрын
@Hemlock Cocktail Archeology is based on Science. Archaeology has proved more than 50 people from the bible to be real. EVIDENCE IS THERE YOU JUST HAVEN'T LOOKED FOR IT.
@davidtompkins5000
@davidtompkins5000 2 жыл бұрын
@Hemlock Cocktail Xin Chen was indicating that the electron transfer chain is evidence of design. The video narrator himself remarks twice the similarity to power plants. Those are designed by engineers. A consistent interpretation of the mitochondrial process would be that it was engineered. That's the argument.
@guilhermeg1182
@guilhermeg1182 4 жыл бұрын
Where did the H+ íons come from? Is it from the water?
@umu-i-d2785
@umu-i-d2785 4 жыл бұрын
If I remember correctly from NADH
@kirschkern8260
@kirschkern8260 4 жыл бұрын
Fat or Faty acids play a big role too. But they build the membrane i think.
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