RISK OF TWINS WHEN TRANSFERRING 2 EMBRYOS

[@locsofnature]

I understand the risks with multiples but those same risks come with natural multiple pregnancies.

[@karalewis8654]

When an embyro splits it will result in identical twins. Identical twins are higher risk than non identical twins because they often share a placenta. Non identical twins will have 2 placenta providing nutrition to the baby vs both babies have to compete for them same resources. The chances of an embyro splitting after a frozen embyro transfer is 1%. The chances of an embyro splitting when conceiving naturally is only .3% which is alot less likely. Most twins that are conceived naturally are not identical which makes them lower risk (1/3 are identical vs 2/3 are not).

[@locsofnature]

@@karalewis8654 this makes perfect sense thanks for the insight

[@Luckyforus686]

@@karalewis8654when two embryos are implanted we are usually talking about non-identical twins though. Two sacs. Lower risk.

[@JesuisFlay]

@@karalewis8654ohhhh

[@ishmish6155]

Hmmmm. I wish I watched her video before I conceived and I would have chose one embryo at a time and wouldn’t have lost my day old baby. Twins are HIGH RISK.! I was one of those who felt doctors were exaggerating. But again I did one embryo and it didn’t stick. Maybe I was hyper stimulated. Then we did two. I had hyperemesis. Meaning I did not eat or drink I was given a pic line . I threw up 20 times a day . I had blood infection. My water broke at 19 weeks with my baby girl. I gave birth at 26 weeks and she didn’t survive . The boy survived. I would have chose one baby first and then the other. It’s been almost two years but the grief is still in my heart. You just get used to the pain but it doesn’t go away Pls do one embryo to anybody reading this. If it splits then that’s out of your control and you did your best ❤️

[@CharlotteG754]

I’m doing IVF and I want to have twins. This is due to my age, and a number of other considerations. I would prefer to hear the risk % of those bad outcomes as I would expect them not to be very high.

[@SarahTiffanyPark]

I had a double embryo transfer last month and only 1 attached! I am now 6 weeks 3 days & had my first ultrasound yesterday

[@marthamorales80]

Did you test your embryos? I didn’t test mine and I can’t decide if I should do 1 or 2 embryos for my next transfer. Our first one failed and was a chemical.

[@SarahTiffanyPark]

@@marthamorales80 No, I had a fresh transfer so we didn’t test the embryos. They were both 5 day blastocysts & my fertility Dr said the quality was great.

[@SarahTiffanyPark]

@@marthamorales80 This is my second pregnancy, my daughter was spontaneous but my partner has low sperm morphology so we just went for IVF. My Dr said It’s always best to transfer 2, so if i were you I’d do 2 for sure! You have a better chance of having a live birth ❤

[@laylawatkins2660]

Do you know if it is possible to use your own embryos as well as your partners at the same time?

[@LollyMadikiza-xw4ok]

​@@laylawatkins2660good question

[@ColeiView]

What if you want to have twins?

[@caramecabe]

Thank you for sharing! Would you consider making a video on fertility and weight? How weight (overweight, obesity) corresponds to fertility?

[@tineline]

Thank you for the video! It's a question we're facing now. After two years of trying, having had an tubic pregnancy we just found out that my other tube is also not functional. On one hand I'd love to have twins so I'm finally done with the getting pregnant part. But on the other hand I want the best chances for baby and me. For me the psychological part weights in too.

[@tsizzle]

Thank you Dr. Anu for the info regarding risks of transferring 2 embryos for twins with IVF. A follow up question: given that a woman is 40, and she definitely wants 2 kids. Is it more risky to have twins with IVF or to have one baby first with a single embryo transfer and then wait until a later time to do a second frozen embryo transfer? How good might the 2nd frozen embryo be for future transfer and what are the additional costs? Thanks again.

[@Luckyforus686]

I’m curious where the 50% statistic for twins you mentioned came from. I’ve been researching and finding varying results in the studies but 20-30% seems to be the most common. Also, a lot of the complications you mentioned are for identical twins which only has a 1% occurrence of getting from IVF with two embryos.

[@bashlea]

Ah yes the person who’s “researched” and is more informed than the specialist who works in the field daily. Good thing you were here to correct her

[@amreetdhillon2311]

I really enjoy your videos! I'm starting IUI in March, your video's are very informative and to the point.. thanks!

[@AnuKathiresanMD]

So happy to hear that! Thank you for this message! Best of luck!

[@TheAudi27]

Thanks for the information. Would love to know the stats for the risk.

[@NatalieNumie]

Thank you but if you put in 2 embryos doesn’t it raise the success rate of pregnancy from that 70% success rate you were speaking about with one embryo?

[@CharlotteG754]

If you didn’t genetically pre-screened your embryos - that is still a gamble - but as she said it is also a 50% chance to have twins.

[@tiffyvivo9429]

I’m transferring two 💗💙

[@ruthtriesgolf]

Me too!

[@florrodriguez3479]

Did you ask your doctor if 2 embryos could be transfer or the doctor suggested 2 to be transfer? I ask because I would like to do 2 embryo transfer but I have a feeling my doctor would say no.

[@nesrinealoui6324]

Hello home fyou are Well @tiffy Vivo but dit four embryos still ok ?

[@ilovemyvdub]

Hello, how was your success?

[@lajupeinstyle]

I am doing my 3rd transfer in a few days ( second FET), I am fed up with miscarriages (I had two:7th and 11th week). I have six embryos in the freezer and thinking of getting two back. PGD here is not available unless you have chromosomes abnormalities. I would love to become a mom of one or two healthy babies next year. Do you think two would be better?

[@iamashleylbrown]

There are other tests you can take to narrow down the issue you might be experiencing. I hope you’ve made progress in the last year since writing this.

[@KS-cl8br]

Prefer twins. Having a sibling for your kid is great.

[@samma4122]

But not everyone is able to PGT and most insurances don’t approve this testing. It would be helpful if you included numbers based on IVF without testing and how the numbers/chances change with age

[@AnuKathiresanMD]

Though insurance doesn't always cover it, I still strongly recommend PGT. If patients are unsuccessful after first transfer, we will discuss option for PGT, which after embryos have been frozen is more procedures to put the embryo through and less ideal. For more information on number of embryos to transfer with and without PGT, please see ASRM guidelines: www.asrm.org/globalassets/asrm/asrm-content/news-and-publications/practice-guidelines/for-non-members/guidance_on_the_limits_to_the_number_of_embryos_to_transfer.pdf

[@samma4122]

@@AnuKathiresanMD thanks! PGT was over 5k and cost prohibitive for us. The link is super helpful.

[@AnuKathiresanMD]

@@samma4122 Glad it was helpful. Best of luck!

[@AnuKathiresanMD]

I would also consider another perspective: not doing PGT can also result in more attempts at transfer, whereas doing PGT could be fewer transfer attempts ultimately. From this perspective, PGT can be considered more cost effective (because of less investment in time and cost with transfers). Again, best of luck!

[@samma4122]

@@AnuKathiresanMD when transfers are covered by insurance spending that 5k is harder when you’re already paying for sperm. I also know a number of people who have had failed cycles or miscarriages with PGT embryos. It’s all very hard on whomever is going through it and I know doctors are doing as much as they and science can. It’s just so hard to know what the best choices are - although hopefully with more accessible info and a good team of doctors one has a solid plan.

[@lydianamukasa8089]

For my friend they transferred 3 embryos and only one implanted

[@cindylou4677]

If I'm doing a fresh transfer and place 2 embryos is there an increase risk of multiple gestations?

[@SarahTiffanyPark]

I had a double embryo transfer last month and only 1 attached! I am now 6 weeks 3 days & had my first ultrasound yesterday

[@HALANBRAZIL]

So you guys are against twins to the point of not put 2 embryos?

[@CharlotteG754]

Yeah but it also is age of a mother driven - I think after 35 or later there is a chance to have twins if you want more kids but running out of time

[@kareBare9999]

Hi Anu, can you tell me the definition of a morula? Can it also be called an M1 and M2? I’ve seen the term used before. Can you tell me whether an M1 and M2 embryo has a good chance of implanting?

[@Dreamytresses]

M1 is am immature egg. M2 is mature.

[@emanmosharafa558]

to be born prematurely, I think the chance is 50%, but how common is it for one of the twins to need surgery?

[@babydooll84]

I’m not infertile but I want to do Ivf for twins!

[@dynasticrawford2621]

So do I. I also want to do IVF treatment to conceive twins

[@maryhenderson1166]

@@dynasticrawford2621 same here!

[@tiffyvivo9429]

Same

[@bubbleslovesmichael81958]

Same

[@remyasyam8511]

Same

[@ChaoticBluez]

I’ve had 4 failed IUIs, 1 failed IVF cycle (doc only accessed 1 ovary as fibroid blocking other ovary so had 1 day 3 embryo that failed), 2nd IVF (other doc got to both ovaries) where 1 blast lead to etopic pregnancy, 1 blast in me now pretty sure it’s a failed one, 2 4CB frozen. As 4CB is considered poor graded, I’m thinking of transferring both next time, it feels like a waste of time putting 1 by 1, would save money if they both aren’t going to implant anyway and at least I can do another fresh sooner after all I am 40 years old, started this at 38, any one got any thoughts on if I should implant both as I’m not sure? Is implanting 2 more likely going to stop 1 potentially good embryo from implanting? All I see mostly is only transfer 1.

[@amirahariana5136]

You change your mind and all other things you just said come to India Delhi 14 billion people. Age is just a number

[@Amazinggrace-925]

Hi Anu, I have 2 questions. 1) if the ovulation shows strong positive in OPk (day - 9) does it mean that the egg will be released for sure only in 24 to 48 hours? Or can the egg release vary to different days like day example - day 15 or 16 or day 6 or 7- others days than LH peak? 2)short period cycle (like 23days) are difficult to conceive? Every month it happens correctly on day 23. Trying for 10 months no success. Can you also do a video on foods to eat - men and women while TTC

[@AnuKathiresanMD]

1) The egg should release about 24-36 hrs after LH surge. It should not vary too much beyond that. 2) that cycle length is still considered normal.

[@hijamamarjit9061]

Ma'am embryo is good but not implantation what is the next step

[@EdisonChau]

Very helpful and to the point

[@RohitKumar-wd3te]

Sir I have one baby already and I am going through IVF process i don't want twin pregnancy. But if I opt single ambrion transfer den possibility will be less as compared to twin ambrion transfer. Please suggest me wat sud i opt single ambrion tranfer or twin? Also i want to know if both ambrion survived den is there any treatment available so that out of two, one can be abored.

[@manalahmed7114]

I haven’t tested my embryos. I’m 26 years old and my IVF process is going great, I only have 6 embryos. I’m so confused if I should transfer 1 or 2? I don’t want a negative pregnancy test but also scared about the risk. Please help

[@JusticeFoorAll]

What did you end.up doing

[@carolynsager9922]

Could a short period (2-3 days) be a reason for concern?

[@AnuKathiresanMD]

No, overall cycle length is more important (ie meaning cycles come every 21-35 days).

[@ricardocolon8711]

Great video

[@vanshikavashisht5086]

Thank you for the video. my doctor transferred 3 Blastocyst 2 days back 4aa, 4 aa, 3aa. Lining was 8.2mm on 12th day from periods. Done laparoscopy and hysteroscopy, prp, lipid, ivig and tb treatment also. What will be the chances of conception. I'm 37. First ivf

[@myvarisu]

My embro 3ab 3ab

[@myvarisu]

3ab it's will get successful ahh mam

[@osasmason5289]

Thank you so much

[@knawani07]

What a crappy and a scary explanation..

[@saradhabhaskaran9638]

I think u r an Indian. Why don't u speak Indian accent madam???

[@ChaoticBluez]

What an odd question….Maybe because she was born and raised in America?

[@karlaescobar9908]

Thats not very nice. Why does it matter!?

[@DanielleCarr01]

So does this mean no fertility center will place two embryos at once?

[@SarahTiffanyPark]

I had a double embryo transfer but only 1 attached