RNA interference (RNAi) Animation || miRNA || siRNA || mRNA regulation

[@KevinBolsajian]

I watched at least 15 videos but nobody explained it as clear as you did. Thank you so much🙏🏻

[@RethinkBiology]

Thank you so so much 🥰 keep supporting

[@Shubh7677]

Same here mam

[@RethinkBiology]

Take love ❤️

[@rsingh2001]

You don't know how much it helped me ... THANKYOU SO MUCH 🙏🏻🙏🏻 .. such a clear explanation

[@mirzafarhanghazi]

It was the best and simplest explaiination of RNAi , thank you 😊

[@RethinkBiology]

That's a great honour

[@frankcarrijo]

Very good. Thank you

[@muhammadumarjogezai7353]

Best way of explanation 👍 Thank you so much 😇

[@RethinkBiology]

Thank you! Keep supporting!

[@ayumentari2091]

The best explanation video ever, so clear and complete! Thank you so muchh 🙏🙏🙏

[@RethinkBiology]

Thanks a lot to you too dear 😊

[@adnankhanthebest]

Your way of explaining the concepts is very good.

[@RethinkBiology]

Thanks a lot

[@ibrahimmicheal7473]

This is quite simple....thanks much!

[@RethinkBiology]

Glad it was helpful!

[@schoolbioresearch9853]

Tq so much , I enjoyed watching this 😍😍❤❤

[@RethinkBiology]

So glad!

[@prernaghangas2197]

Absolutely amazing. Thankyou 🙂

[@ashishdangi7946]

Thanks for your efforts👏👏👏

[@RethinkBiology]

Thank you 😊

[@neeloferjan5397]

Amazing 🤩,thanku so much

[@AjaySingh-fh8bz]

very nice

[@katiek9361]

literally slay thank u so much

[@laraibsanjrani1523]

Great, I really appreciate it. You explained it very well 👍🏻

[@RethinkBiology]

Glad you liked it

[@saykar0393]

Great.... !

[@DemetriMaude]

good video :)

[@punm1983]

Superb

[@RethinkBiology]

Thanks a lot, please share if you liked our videos

[@ikinehir]

Thank you, thank you!

[@vladimirputin965]

Thank you❤

[@RethinkBiology]

You're welcome 😊

[@Rome-j1h]

عاش اميتاب باتشان و الله تاليها كمنا نفهم على الهنود 😅

[@pramods3630]

Mam I have a doubt in which condition miRNA and siRNA will gets activated

[@vladimirputin965]

The information is from which book?

[@ayuchaudhary4135]

Hey can you tell me about RITS comples

[@RethinkBiology]

The RITS (RNA-induced initiation of transcriptional gene silencing) complex contains siRNAs and is the major effector of RNA interference. Heterochromatin assembly is associated with large-scale chromatin condensation to regulate a variety of chromosomal processes, such as centromere formation. Below is the link for a Cell article, you may find useful. We will try to make a video on that too. www.cell.com/molecular-cell/pdf/S1097-2765(04)00057-7.pdf

[@ayuchaudhary4135]

@@RethinkBiology thanks

[@joshualaraclure4863]

Isn't AGO1 for miRNA ?

[@nandani6945]

How to apply in plant.. ?

[@RethinkBiology]

RNA interference is a natural process that plants use to regulate gene expression and defend against viruses and other pathogens. It involves the production of small RNA molecules that bind to specific messenger RNA (mRNA) targets and prevent them from being translated into proteins. There are different types of small RNAs, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), that have different origins and functions in plants. To apply RNA interference in plants, researchers can use various methods to introduce small RNAs or their precursors into plant cells. For example, they can use genetic engineering to insert DNA sequences that encode for small RNAs or hairpin RNAs (hpRNAs) into the plant genome. These sequences can be driven by constitutive or inducible promoters to produce small RNAs in a specific tissue or time. Alternatively, they can use viral vectors to deliver small RNAs or hpRNAs into plant cells through infection. These vectors can be modified to reduce their pathogenicity and increase their specificity. Another method is to use spray-induced gene silencing (SIGS), which involves spraying synthetic small RNAs or hpRNAs onto plant leaves. These molecules can enter the plant cells through natural openings or wounds and trigger RNA interference. The applications of RNA interference in plants are diverse and promising. RNA interference can be used to study gene function, improve crop traits, enhance stress tolerance, and control pests and diseases. For example, RNA interference can be used to silence genes that are involved in flowering, fruit ripening, seed development, nutrient uptake, photosynthesis, and hormone signaling. This can help researchers understand the roles of these genes and create plants with desirable characteristics. RNA interference can also be used to silence genes that are essential for the survival or virulence of plant pathogens, such as viruses, bacteria, fungi, nematodes, and insects. This can help plants resist infections and reduce crop losses. If you want to learn more about RNA interference in plants, you can check out these sources: (1) RNA Interference Technology in Plants: Mechanisms and ... - Springer. link.springer.com/chapter/10.1007/978-981-16-6974-3_10. (2) RNA Interference Past and Future Applications in Plants - MDPI. www.mdpi.com/1422-0067/24/11/9755. (3) RNA Interference- Definition, Mechanism & Applications - BYJU'S. byjus.com/biology/rna-interference/. (4) Exploiting RNA Interference Mechanism in Plants for Disease ... - Springer. link.springer.com/chapter/10.1007/978-3-030-35955-3_10. (5) RNAi: What is its position in agriculture? | Journal of Pest Science. link.springer.com/article/10.1007/s10340-020-01238-2.

[@srijandey87]

Are you bengali?

[@merajbegum5978]

Better not to add music!

[@RethinkBiology]

See our latest videos, we don't add music 😬

[@NITISHKUMAR-un2no]

Background music is disgusting

[@RethinkBiology]

Visit our newest videos with no background music

[@warmedpuma2024]

It was a good choice of music, so be quiet jit.