Nano-medication should be the last-ditch treatment for diabetic foot ulcer. If excessive glucoses in the blood can't be brought into cells for utlization, it's impossible to cure diabetic foot ulcer. Nanoparticles of nano-medication are amphiphilic, i.e. hydrophilic as well as lipophilic. Through caveolae, endocytosis, nanoparticles can piggy-back glucoses into cells, without insulin.