Roy Parker (U. Colorado Boulder/HHMI) Part 1: mRNA Localization, Translation and Degradation

www.ibiology.org/genetics-and...
Part 1
The control of mRNA production and function is a key aspect of the regulation of gene expression. In the first part of this lecture, I will discuss how in eukaryotic cells, the control of mRNA localization, translation and degradation in the cytoplasm allow for the proper regulation of the amount, duration, and location of protein production. The basic mechanisms of these processes are understood and reveal that the mechanisms of localization, translation, and degradation are interconnected. The unique properties of each mRNA are dictated by its intrinsic interactions with cellular machines, as well as its complement of mRNA specific RNA binding proteins and miRNAs. Strikingly, mRNPs are dynamic and can be modulated by protein modifications as well as by modification of the mRNA itself, thereby providing a diversity of targets for the regulation of mRNA function in response to extracellular signals.
In 2012, Roy Parker joined the University of Colorado, Boulder after many years at the University of Arizona.

[@medielijah]

My teacher spent more than 3x the time this lecture took to record but I ended up understanding less than 1/3. Excellent review, thanks a lot. Was starting to give up on this subject. But after watching this I am so motivated again, many thanks.

[@Quantumash1]

Thanks a lot Sir This video is very helpful in understanding mRNA localization, translation and degradation.

[@darioc.ramirezphdmsc2684]

Elegant and comprehensive lecture!!! Loved it, sure my students will appreciate it as well

[@ysviewpoint]

Enjoyed it! Looking forward to part two.

[@WorldCollections]

After watching this, I get the feeling our professor is deliberately trying to confuse us. How important is to organize information! Thanks!

[@sageman1458]

very informative thanks

[@Quantumash1]

Sir Is it possible that the videos be broken up into shorter parts. i.e., less than 30 minute parts?

[@bhnsina]

Goood video and he reminds me of the professor in The walking dead season1, Any1 else seeing it? :D

[@makaylabrandon5841]

these people are theives stole from louise brandon justiceeeeeeeeeeeeee!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

[@trafalgar22a8]

This presenter has unclear diction.