We Got Our DNA Tested, Here's How It Actually Works

Trace and Amy get their DNA test results, and we talk to an expert about how scientists actually get genetic information out of DNA.
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Read More:
How does DNA testing work?
www.bbc.co.uk/science/0/20205874
"Parental, forensic and genetic testing look for similarities in the genetic markers between two biological samples. Because all cells in the body contain exactly the same DNA, samples can be taken from almost anywhere in the body, including skin, hair follicles, blood and other bodily fluids."
How is genetic testing done?
ghr.nlm.nih.gov/primer/testin...
Once a person decides to proceed with genetic testing, a medical geneticist, primary care doctor, specialist, or nurse practitioner can order the test. Genetic testing is often done as part of a genetic consultation. Genetic tests are performed on a sample of blood, hair, skin, amniotic fluid (the fluid that surrounds a fetus during pregnancy), or other tissue.
The family history: the first genetic test, and still useful after all those years?
www.nature.com/gim/journal/v14...
"The family history has its origins in genealogy and over the past century has become embedded in clinical practice. Its importance in specialized circumstances is unquestioned but largely untested. Moreover, the relevance of the family history to common diseases, especially in an era of genomic markers that convey risk and the emphasis on 'personalized medicine,' must be given careful scrutiny."
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Written by: Trace Dominguez

[@TraceDominguez]

I don’t know if you caught that bit about Maple Syrup Urine Disease, but we spent so much time looking into it later! I wanted to share it, but it didn’t make it into the video. MSUD a super-rare dietary disorder and it is fascinating. People who have MUSD must have a special diet their whole lives, because their body cannot process certain amino acids (protein building blocks). It affects 1 in 185,000 infants worldwide and *can* cause serious problems if it goes untreated. The fact that Amy, a Canadian, had a disorder with the name "maple syrup" really caught us off-guard, but hopefully, the fact that Amy is a carrier can help raise awareness! Vaya con science!

[@ursaltydog]

And btw.. which test did you two take? the 23andme or another one? And if it was 23andme, did you take the 99 or 199 version, and how satisfied were you?

[@yyyyyyyyyroto]

Trace Dominguez What complications?

[@ursaltydog]

Is Amy sure she doesn't already have this issue, instead of being merely a carrier? The reason I ask is, that mutations in the specific genes that create MSUD, cause the body not to be able to break down proteins from particular, protein-rich foods such as dairy products, meat, soy, gluten, eggs, nuts, whole grains, seeds, Mutation in any of these genes reduces or eliminates the function of the enzyme complex, preventing the normal breakdown of isoleucine, leucine, and valine. She's already been identified as lactose intolerant... Tell her to be aware of any symptoms that may indicate a late onset of the disorder in herself.

[@monkeyemperor1223]

Maple syrup urine disease is an inherited disorder in which the body is unable to process certain protein building blocks (amino acids) properly. The condition gets its name from the distinctive sweet odor of affected infants' urine and is also characterized by poor feeding, vomiting, lack of energy (lethargy), and developmental delay. If untreated, maple syrup urine disease can lead to seizures, coma, and death.

[@Meirstein]

It's the $199 23andme. The $99 version doesn't do health or carrier reports.

[@universeq6r]

My DNA test showed I'm 30% Mexican, so I built a wall around my DNA and made my amino acids pay for it.

[@yvonnew2688]

President Donald J. Trump 😂

[@eman0828]

President Donald J. Trump Mexican is not a race 😂 Mitt Romney's father is Mexican and is he's white.

[@palebluedot7435]

Eman 08 do mexicans have a certain appearencr

[@palebluedot7435]

Eman 08 yes but agian when someonr says mexican do they typically think of a specific mezo american look ? ya when someone says Mexican they mean mezo american. technically race is such a fluid word it can mean specific mezos from mexico or the entire modern gene pool of mezo so yes you can be racist toward mexicans and you can have mexican DNA also is german a race .... no but it will show up as part of your dna origin so yes you can test DNA and it can comback mexican mexico isnt as mixed as the carribean

[@eman0828]

pale blue dot​​​ Again Mexican is a nationality, you can be black, white, native American, Asian mixed race. Ask the same question what does an American look like, are they all white people? 😂😂😂 just like I said about Mitt Romney's father and he's a white Mexican born. Christina Aguleria's father is Ecuadorian and she's white. My father is a white boy with blonde hair and blue eyes with the last name Ortiz and his grandparents are from Puerto Rico. Even Trace Dominguez is mostly white as he's a White Caribbean just like my father as Trace looks like someone from Spain.

[@Master_Therion]

I'm so sad. I failed my DNA test :(

[@ImAFanboy]

Master Therion Damn

[@keriezy]

Master Therion Funnier because of your name. Dumb dumb dumb dumb dumb! But I liked it too!

[@AnfalasHerdsman]

what you mean? is this a joke i didnt get ? please dont be cruel guys ;-;

[@Master_Therion]

Soufiane Artwood Yes, it's a joke. You can't "fail" a DNA test. It's not like a test you take at school. ^_^

[@AnfalasHerdsman]

Master Therion hahaha got it!

[@NerdRate]

Vsauce Michael here: "you guys want some spit facts?"

[@jamesfra1311]

Adi Witko Ohohohohoh yes please my dude

[@hiftylonghead892]

Adi Witko GREAT MEME 10/10

[@AnfalasHerdsman]

mman i laughed my ass off so loud , thanx

[@rivercat962]

Where did you get your specific DNA kits and which lab provided the results in the format you showed us in this video?

[@200odd300]

where did spit facts come from??

[@gimmethemtoes]

hears "maple syrup urine disease", pauses video, opens new window, googles maple syrup urine disease, then goes back to youtube, searches for maple syrup urine disease videos

[@danielwilliams967]

just did, scrolled thru comments to see if anyone else had... Hello.

[@humanity3.090]

Glad you are "staying curious".

[@CLmssan]

Naaah, medical student, already knows the disease, doesn't pause the video

[@nasser314]

I like how the DNA thingy becomes Yellow when it hovers over Asia

[@danielfloyd.]

lool. Not all of Asia is yellow though so thats just a stereotype

[@SuviTuuliAllan]

No, they turn red when they drink alcohol.

[@ekscholl]

Suvi-Tuuli Allan lmao

[@thearchitect3497]

João Pedro Nasser haha

[@thearchitect3497]

João Pedro Nasser not all Asians are yellow tho.

[@jamesfra1311]

Dna test just came in, I'M A FUCKING LEMON

[@shawnf.672]

james Fra im a potato

[@MadameRaven1]

james Fra I'm supposed to be Emperess of Earth.

[@josephleece682]

Mother Raven I'm supposed to usurp your throne and lead the people into effectively individually self governed

[@juubes5557]

Don't worry about it. 95% of American population are vegetables all their life.

[@KuraSourTakanHour]

james Fra Lemongrab?

[@nishitdua]

don't trust an edited comment

[@SandlotRider]

Epimenides' paradox?

[@MrC0MPUT3R]

I don't trust you...

[@pingu4238]

you can trust me though.

[@alexturlais8558]

Nishit Dua what if you spell something wrong

[@Ethan_Roberts]

This means that... I shouldn't trust you but you're right meaning you could have created a quantum paradoxical super wormhole dividing some part of space time into two halves and completely stopping the universe from expanding which in-turn gravity collapses the boundary of the universe and will make the big crunch a reality. wow

[@Mr._Lechkar]

The final episode to be branded as DNews. R.I.P. DNews 2012 - 2017

[@ItsTrueFilms]

ive done this exact thing still waiting to see if im retarted

[@apple54345]

Do you like spoilers?

[@carlsson614]

Ha

[@Anmar__]

Judging by the name, I could tell.

[@sbritton1313]

are you a liberal?

[@jgill3881]

Lmao

[@rs4runner]

If you don't mind sharing, can you link us to the DNA service that you used for the video?

[@princessbuttercup8954]

I would like to do a DNA test but I can't figure out which one to use. I tried to find info in the description of the one Trace and Amy used but couldn't find it. Any suggestions please?

[@639426]

What company or where did you get the DNA testing? I found one for Ancestry.com but i don't want to just learn where i am from but also get likely hoods of diseases, or any current traits. Can you leave a link?

[@Vibinator]

Dnews used 23 and me (its in the tags)

[@carrieonabaldwin6089]

JD M 23andme.com

[@danbreckenridge1337]

Love at its finest 5:55

[@heartlessgaming2250]

How did you guys get the DNA test kits. And are the results that came later part of the deal when you got your test kits?

[@mezosistolic]

Could you please tell me what test did you use. What firm? From which company? There are a lot of tests on the market and I want just the right one, or the most complex.

[@capriaricho]

Im Ethiopian and I did a DNA test a while ago and my biggest two areas was East Africa and Middle Eastern/North Africa. Then I found out I had European in me and < 0.1% Native American (What!?). Im not sure if I should trust in the Native part but a lot of people related to me on 23andme have Native American and Oceanian 🤗 I had a bit unassigned but DNA test for East Africans are a bit sketchy (because most don't have as much testings on us) so it's hard to know if the results are accurate enough lol.

[@ibrahimabdullahi5698]

geo . zephyr same with Somalis, it's an ancient admixture

[@adolfodef]

There is unconclusive evidence of certain species of plants native from central and north america being present on ritual burials on Africa as far as 8000 years ago [with Tutankamon´s cocaine_in_his_hair being just the most famous]. It would not be impossible for any ship able to cross the Mediterranean Sea on a regular basis to do the same through the Atlantic with a lower probability of success (and back with some imported people in them to replace the lost crew members).

[@andrep4805]

geo . zephyr I'm African-American, and I had trace amounts of Melanesian Bantu, and Caucuses, which I suspect could be East African or Madagascar ancestry. I used Ancestry.com and they focus on West Africa. I look forward to the reference populations expanding.

[@rainyday4970]

Native Americans ARE Asian, by heritage. They migrated across the Beringian land bridge (that used to exist between Siberia and Alaska) thousands of years ago. Then they spread out through all of the Americas (North, Central, & South America). I wish these DNA test websites would include this human history lesson in their explanations, because I have seen it confuse a shitload of people.

[@rainyday4970]

Google "mongoloid", darling. It is a controversial term for "Asian"! & The Mongols themselves WERE Asian!

[@AnEpicNguyen]

Maple syrup? She is Canadian… 😄

[@Karthik-ll5kv]

Jimmy Nguyen maple taste good.

[@ksub91]

Doctor Sanders has a wonderful accent and voice, it's so soft, he should start make audiobooks.

[@zoeblake6740]

Hey. Where can we get this done? The most detailed version. I want to get one! I'm in the UK :)

[@tougenomikado]

I can just imagine.... waking up... smelling that breakfast smell.... running towards the kitchen..... "wow mom ... you made pancakes!!"...... ... "No that was just your sister peeing her pants" =(

[@LulitaInPita]

Ian Enciso dead lmfao

[@TheCRAZYEYES1000]

Ian Enciso My pee smells like cheerios guess that meens i got Hunnynut Pee Disease

[@cooliipie]

This is a thing? I have it lol

[@RoryRose_]

Is is Friday yet!? I wanna play Zelda...

[@RoryRose_]

Yeah! that comment wasn't related to the video! DEAL WITH IT!

[@RoryRose_]

I'm dabbing.

[@jluna231]

M Martin sick invite

[@FieryKitsune1]

Hop over to Australia. We get Friday 12 hours sooner.

[@eugenio5774]

where did you get the kits? me and my boyfriend want very badly to have our dna tested, we're uber curious about it!

[@Theuntamedlover]

You guys geeking out over your genes makes me smile :D. Thank you.

[@contingenceBoston]

Aw man, Amy is wicked cute.

[@Jakub680]

Contingence Why the "awww man"

[@liberalbias4462]

No one uses the word wicked.

[@charlesstjohn1233]

I’d tap. Unconscious of course

[@aquamarinedream8304]

I am: 29% Spanish 26% Native American 14% great britain 13% Irish 9% Italy/Greece

[@SRC-lo2nc]

K

[@ImperiaGin]

Aweosme video really did a good job of explaining the process.

[@sebbysebbseb]

This was really interesting. Im gonna get a kit myself, thanks!

[@mayhemdiscordchaosohmy573]

I would like to ask you at D News a perplexing question. (Perplexing for me at least) Earlier this year, San Francisco was treated to an unusual sunset, the "Belt of Venus" could be seen on the western horizon and ALSO the eastern horizon! How the HECK does that happen?!? It was beautiful, apparently...although the vid I seen didn't do it justice!

[@MrJherime]

Wow that woman is exceptionally beautiful. #smitten (Trace is exceptionally beautiful too, I just don't swing that way.)

[@MadFluffysterXaines]

But if there was a playground nearby, I'd swing with Trace :D

[@japaris75]

Well, I swing that way and I wonder if DNA can tell if we are to have good looking children or parents or if we are good looking. Trace is very good looking.....just saying

[@WilliamMerzlak]

MrJherime There's a DNews video where you get to see her practicality naked. just with a little black bar over her nipples and vagina. It was something to do with sleeping naked I think.

[@cadenrolland5250]

Amy Shira Teitel Check Amy out on Twitter: twitter.com/astVintageSpace Vintage Space here on KZbin as well

[@maxsimes]

betcha kevin sapcey swings that way

[@fullmetalfunk]

What service did you guys use for the DNA testing? I'd like to do it.

[@ozdergekko]

So much fun! I just *love* Amy!

[@alexbautistakrayzieb]

THE BIGGER PICTURE: WE'RE ALL RELATED!!!

[@selihter]

It has to be because I am not from an ape lol

[@qqq1701]

Can we get my DNA say I'm supposed to marry Selena Gomez? Then I can go to her and say I'm sorry but it's science, we have to hook up. Let's make the best of it.

[@qqq1701]

k

[@qqq1701]

Why not?

[@ernestomartinez6745]

qqq1701 this is poorly written

[@Arduex2020]

What "brand" test kit did you use?

[@rubenyoranpc]

Where can I get one of those kits and how much are they?

[@zellustar2756]

The last video of DNews in my book. For now. Unless they brought back the usual fun and love in their videos just like this. RIP.

[@Whichendup]

But where did you get tested and how can we get tested if we wish also.

[@robertct06]

DeathbyDoughnut 23 and me

[@noahtheiring858]

What DNA test kit did you use? Is something like this available to the public?

[@Owlswing39]

What testing service was used for the tests in the video?

[@talideon]

"Maple Syrup Urine Disease" AKA being Canadian. :-)

[@rainyday4970]

Actually it's a deadly disorder. It can also lead to serious mental & physical disabilities, if it is not caught in babies fast enough!

[@miyo7376]

I love genetics. Sciencium just uploaded a really cool video on 6 DNA as well. Might make a video about genetics on my channel.

[@NateCrownwell]

this was awesome, what is a good company to get the test done?

[@aci25tv]

How much it will be to get this test done? I am interesting in having this test done.

[@juubes5557]

How much did it cost?

[@DA-bm2mj]

Illidan Stormrage any chance it gets cheaper substantially in the near future?

[@maryfoxx6019]

Alot.

[@tseries6622]

23andme costs around $60-70 Ancestry costs closer to $100

[@Luke.Raistrick]

Why did u guys change the name to seeker

[@AnhTrieu90]

Where did you guys ordered your genetic test kits?

[@Q.Lawrence]

My apologies if I missed it, what company did you use for your testing? I did the same thing but the results weren't as detailed.

[@sapointi]

always thought trace was Cuban. pretty positive he's Cuban now. those results were really similar to my Cuban grandpa's results

[@eman0828]

Sapa Inti it wouldn't surprise me as his results are typical of a white Caribbean. He's whiter than my grandfather that is also mostly Iberian as I'm 7% Native American as I'm three generations from Mayagüez, Puerto Rico. Trace and I could possibly be distantly related since these island populations are known to be Endogamy populations. I have several thousands of Endogamy Puerto Rican cousin matches.

[@sapointi]

Eman 08 yeah my sisters dad is Puerto Rican he also got thousands of cousin matches, while my Cuban grandpa didn't even have a hundred and my Ecuadorian family had under 100 too. but my Cuban grandpa's dna is really close to trace, 95% European, 3% north African,

[@HairyBottom]

Sapa Inti Most Cubans today are white. Anything below about 25% means nothing.

[@johnnyd6953]

HairyBottom not really, especially if the 25% is from something like African

[@eman0828]

HairyBottom​​​ 1/4 is pretty significant to be considered "Mixed" race. 2% not so much. A lot of White Puerto Ricans are in the 60-70℅ European range but they are still multiracial compared to one coming straight out of Spain as they are not your Charlie Sheen "White". Charlie Sheens real name is Carlo's Estevéz that is 100% European of Irish/Galician. My father looks just as white as Charlie Sheen with the last name Ortiz a blonde blue eye but he's multiracial generationally mixed of European/African/Taino.

[@houchi69]

Maple syrup urine disease...sounds like a disease I wouldn't mind having...

[@robertct06]

houchi69 apparently people can die from the disease if they eat to much of a certain type of food

[@cerezabay]

If left untreated it can lead to Seizures, Coma, or Death. Have fun.

[@paulwebb2078]

houchi69 oh gad

[@houchi69]

Well...I don't have it...so, thanks! :)

[@ingmarhendriks8172]

That was informative and funny! Thanks. Great video.

[@edo471]

Is there a video of the whole reading the results? I'm interested :D @seeker

[@Curtis006]

I want that moray eel shirt

[@michaeltheatlantean5329]

Well, it's a good thing they have all of your DNA files on record now. Don't be surprised when you see your long lost "twin" brother walking around.....

[@AadharTyagi]

KingGhostDragon I don't see the problem, it would be so cool

[@michaeltheatlantean5329]

Nah, I'm not for sale and neither is my DNA, Your DNA are the basic blocks to what and who you are. While you're entitled to your opinion, Don't say I didn't warn you when your identity no longer belongs to you.

[@AaronHerbst]

identical twins do not have matching fingerprints

[@nickroy681]

I'm a little late on this but what company did you guys go through for the testing?

[@SeriouslyLeslie]

They did the DNA video!!! Yay! I requested this a few months ago.

[@bobbybillyson7457]

Why is the name seeker?

[@deltainfinium869]

The last good video on this channel. Rip DNews. You will be missed.

[@comon44444]

Which DNA testing kit did you use? I kinda want to do this!

[@theFameWolf]

What company did you use? I see no links or references

[@rodylermglez]

This is kind of an horoscope with a tinge of science.

[@vishalSharma-wh3hr]

carrier which one at&t or Verizon 😁

[@dallasparty316]

vishal Sharma T MOBILE

[@haveoneonme]

vishal Sharma giffgaff

[@charlessalalila382]

vishal Sharma either, I don't live in U.S. ✌🏼️

[@volka2199]

vishal Sharma I have American Telegraph and Telephone company.

[@TheCRAZYEYES1000]

verizon because i live in montana and that stuff speads like wildfire

[@louissimanovich]

Which kit or company did you use I can't find a link

[@GrimmWarrior19]

Okay so where did you guys buy your test kits at?

[@Gustavo_Ramos]

want Dnews back '-'

[@splayjose2782]

This is last video of discovery news

[@Saphyu]

Where did you guys test your DNA?

[@dw4467]

Is there any reason why a Dnews video is on Seeker's channel? Did someone mess up?

[@Derpuwolf]

Why is this channel called Seeker all of the sudden?

[@spotfleri5779]

i thought this channel is called Dnews.

[@soomhun9239]

AmplifireZ it was seekers whole the time.. :/

[@JoseGonzalez-rt5fk]

Anyone know the best site to order and test my DNA?

[@Cyrah_]

You guys used the 23&Me services?

[@ZeusTheImortal]

Guess no one pointed this out but Here lies the last DNews video

[@Kivalt]

2:59 But I thought race was a social construct!

[@BrotherAlpha]

It is. DNA can be used to tell if you are German vs. British. That doesn't mean German and British are two different races.

[@zkerekere5096]

Kivalt clearly it's not

[@PabloBatistaArq]

Kivalt he did not say that race exists. it just happens that geographic isolation keeps certains genes in a area

[@SuviTuuliAllan]

Did nazi that coming...

[@volka2199]

Kivalt Depends how you define race there are many different groups of humanity like the mongoloids, Caucasians, etc... If they want to call it a race they can. Each "race" has fundamental differences in face structure and pigmentation.

[@albastrea90]

what is the name of the kit used?

[@MonkeMane]

Just wondering when trace is coming back to D news plus? Or seeker plus whatever you want to call it

[@zapfanzapfan]

"Maple Syrup Urine Disease" must be the most Canadian thing I've ever heard of :-)

[@jookpook3535]

The grey haired guy in the office has such a sexy voice (said suducdevly)

[@tseries6622]

Take 330 seductively**

[@sharath9893]

That guy is so calm

[@mslovely0914]

What DNA kit did ya guys used?

[@patrikkivekas5261]

Hey what's the deal with your branding/channel name? Did you start out as Seeker Daily and switch to DNews and now you're Seeker again? Pick a name and stick with it? :)

[@DoctaOsiris]

I think you two need to get a room and get it over and done with! 😂

[@Jakub680]

Orion Osiris lol

[@michaelphillips7750]

Trace would put it in the wrong hole.

[@HapZungLam]

How do I get the test. And how much to do it?

[@Yes-df3xx]

One of the funnier D-News episodes! Also, why did you change the name of your channel?

[@Gibbo1337]

I dont care about DNA i care about DNEWS WOOOOOOOOOOOOOOOOOOO kill me tomorrow

[@Vikas.03]

dont worry kakashi pain is coming to leaf 2mrw😏

[@maryfoxx6019]

its still science and everyone else liked it so :-p

[@kalebzeroone9585]

WTF WHY IS YOUR CHANNEL CALLED "SEEKER"????!!!??!?!?? wtffff

[@DarkGaming251]

The background music in the video is fire. Seriously.

[@theman1860]

What kit did you use?

[@Justgoodvids]

Link to ordering the kit from the same company?

[@greenthumbbe]

Hi , i would like to know ,how and where can i sent my spit sample ? Would love to help the science community .....thx

[@KennyKenJm]

how do I order one of those kits?

[@OutlawMaxV]

Dr. Stephans voice is sooo milky smooth, and that slight accent, I could listen to him all day!

[@kimoykalinago4154]

does anyone know where I can get one of these DNA kits from??????? I want to trace my roots

[@Julia76087]

where did you order your kit?

[@cutsceneenjoyerzz]

Where can we get this type of test??

[@johnfortich]

Where do we order the kit?

[@DodgeThis]

Where did you get the kit?

[@JoseMartinez-df2db]

Which DNA service did you use?

[@viktoriaj.5973]

Where did you order this test from?

[@JacksLostThought]

they never said which kits they used, I would really like to know.