Side Effects of Biologic Medications

Vicky Ruffing, RN, shares some useful information on possible side effects when using biological medications.

[@isayc2208]

I'm 58 years old. I've been injecting Humira and taking Methotrexate tablets for almost 20 years. These did not prevent me from having complex wrist replacement and many surgeries to correct that replacement. One of the side-effect is that I developed scars in my lungs and wrongly diagnosed with ILD (interstitial lung disease). I also keep getting coughs and cold. My immune system was so weak. I learned about Ketogenic diet on KZbin from proper medical doctors who believes in alternative treatment and food as medicine and fasting. I stopped all my medication and been doing Ketogenic diet for maybe 2 years now. I lost weight, no more knee pains, no inflammation (or very minimal in my thumbs), I'm able to walk my dog to the forest near us everyday without a fail while doing some stretching. I felt stronger and more cheerful. Maybe not for everyone but it works for me. I hope people and real medical doctors will find time learning about it.

[@uresla6321]

Happy for you! I wish i find proper treatment for my AS 😭😭

[@MarceloPaciorek]

Same here. I got PsA, and Im on a plant-free diet.

[@gnothiseauton8684]

I’ve just been offered it- but at 49 I’m not going to risk messing around with my immune system not to mention the other risks- I think I’m going to stick with diet adjustments, ketogenic alternatives, exercise and fasting. I’m too nervous

[@dongskijyu8583]

Same here

[@tiportangeles2696]

My Dr. is pushing Humira on me, I said, Hell NO! Even if it were free, still Hell to the NO!

[@karendeaderick6017]

My husband got a pacemaker pocket infection, it had to be removed and placed on the other side of his chest, all the leads had to be removed also. Be very careful with these types of medications!

[@Allia90]

I been on Enbrel for 7 years and the only thing i would get was kidney infections from time to time, overall it helped me put my RA in remission. I got off of it 9 years ago, still in remission this days.

[@sublimerecipes9909]

Now are you having body pains???did you take enbrel for 7 years and how it helped you?

[@baboom007]

@@sublimerecipes9909 i think she is dead

[@Allia90]

@@sublimerecipes9909 Sorry for the late reply for some reason it never showed your reply. If it still helps: I still have body pains but is mostly caused by the whole damage RA did to my body for 2 years i was without treatment at all, i was 13 years old when my RA started and did a lot of damage to my joints. If i wasn't starting Enbrel when everything else did not have any result on me i would probably be in a wheel chair now. I am 30 years old now and i'm doing pretty good, i hurt at times when the weather changes or if i make more efforts but i rarely get inflammation in my body, just my ankles if i walk for too long.

[@Allia90]

@Shaqeeta Cobb Any medicine is a risk. That does not mean it will happen to you. Even a painkiller has a ton of adverse reactions and could cause you a heart attack. Plus doctors keep you under observation while you are taking Enbrel or any other biologics. Like blood test, Lungs Scan etc.

[@Allia90]

@@baboom007 Nu am murit nu. Si nici nu am de gand :)

[@LewyLewy2008]

Very helpful, thank you.

[@cherielatson9573]

Thank you ma'am, this info is very helpful.

[@blankblank5524]

Thanks so much.This was very informative 🌟

[@austinwest8202]

My treatment progression over 6 years of crohn's was prednisone, remicade (infusion every 8 weeks, worked for 4 weeks). After my presenting symptoms progressed from diarrhea to crohn's related arthritis attacks, I was on Humira. This was very for 2+ years until I had my second Moderna covid vaccination. I went into a flare less than 24 hours after having no reactions to the first or second injections. The flare lasted for nearly 7 months. We switched to Stelara and it has been very effective for the past year. I am convinced there was a connection with the moderna/humira and my flare. When I received my infusion for Stelara, the nurse was emphatic that I was correct as she had a friend who experienced the same reaction. Your take?

[@n.r.s5534]

Currently on entyvio and Im suffering from chest infection and severe bone ache that wakes me up from my sleep

[@manikyamusharani9086]

My uncle is having fever for the last 25 days. He had biological injections 6 months ago. All fever work up including CT scans are normal, except mild thrombocytopenia. Please suggest further course

[@annlyon.2040]

Is Truxima one of these ? I just found out that my doctor want s me to have infusion of this. I hate drug reactions ! I can hardly take pills for my RA !

[@filipinophreak]

Im on tremya, ive had several headaches and diarrhea..

[@Marreroortiz]

What about if i have AUTOINMMUNE HEPATITIS ?

[@ThatsSoAlixNews]

Taking benlysta infusion experiencing sore throat..running nose just all sudden

[@mariastephenson839]

Cosentyx can cause this symptoms?

[@HopeinJesus1987]

The stakes are very high. I pray I will be OK, very nervous as I just started Humira today 🙏

[@donnamontanarella2403]

I will say a prayer for you. God bless and protect you dear.

[@HopeinJesus1987]

@@donnamontanarella2403 🙏🙏💛💛💛

[@rezstitution]

any updates?

[@palafox2237]

Sudden cessation of enbrel (very 1st biologic) for rheumatoid AR caused palmoplantar pustular psoriasis. To treat THAT the dermatologist tried Cyclosporine - affected my liver function - stopped. Cosentyx caused severe esophageal thrush - stopped. Can't tell me the side effects are rare! If you can live without biologics & they are not absolutely necessary DON'T AGREE to ANY of them.

[@HopeinJesus1987]

Thank you for sharing. I truly hope you are doing better now. Blessings to you 🙏

[@brody5211]

Weight gain is a given on these

[@jeffwolf8018]

I've tried 6 or 7 different biological monoclonal antibodies for Crohn's in every last one of them either does nothing at all or destroys me. Strangely enough the worst one was the last one I tried and was stelara. That left me with no energy and bed bound for weeks at a time for almost 9 months. I think I took it three times.

[@bmc5075]

Any one starting or on cimzia

[@rca6576]

My mother was on Remicade for her RA. She got histoplasmosis and died. My husband has RA and I'm seriously worried about him taking any biologics.

[@LyubomirLalovMulti]

This is glorious, I've been looking for "lupus side effects medication" for a while now, and I think this has helped. Have you ever come across - Denmelia Jansabella Builder - (should be on google have a look )? It is a good one of a kind guide for discovering how to treat lupus without the headache. Ive heard some incredible things about it and my friend got cool results with it.

[@lavitra.]

@@LyubomirLalovMulti shut up scam

[@donnamontanarella2403]

I am so sincerely sorry for the loss of your mother. I can understand why you are concerned about your husband. I pray that he finds relief. I had an anaphylactic reaction to Remicade with my second treatment after I had only gotten the equivalent of a tablespoon (30 cc's) .

[@susanswope4924]

This is insane ,if you have heart failure?????Thanks I had migraines for years and my toes went numb.

[@phxbarb]

severe depression, panic attacks and anxiety can also occur. Never do Humira if you have any depressive symptoms in your history. Very bad sinus infection required antibiotics to get rid of it.

[@HopeinJesus1987]

Thank you for sharing. I am nervous as I started this treatment just today 😓

[@tdeviller]

@@HopeinJesus1987 I started humira July 1st ( for crohn's and inflammatory arthritis in my si joints ) and already feel so much better/less pain! I feel great so far as in no side effects. This drug has given me my life back 🙂

[@HopeinJesus1987]

@@tdeviller Tania, that is so wonderful to hear! It give me hope 🙏

[@uresla6321]

@@HopeinJesus1987 how are you now🥺 my AS getting worse day by day rheumatologist suggested me Humira but I’m so scared for it’s side effects 😭😭 I’m female age 42

[@uresla6321]

@@tdeviller happy for you Tania!i give me hope🥺🥺 i have ankylosis spondylitis 😭😭

[@donaldtenn-2572]

I was on Humira(Adalimumab) for 15 years. The only issue I noticed was, as stated, my immune system was considerably lower, and, after about 12 years it was not as effective. Then the unknown variables with what was then called the Coronavirus came about and I just quit taking the Humira. I KNOW MY BODY, I told my doctors and they also agreed, "That is probably a good idea" Now, 15 months later, just had my 3rd shot of Enbrel(Etanercept). I have read reviews in Amgen's data stating some people have positive reactions to Enbrel after 1 or 2 weeks. I believe a positive outlook is important, but, I also believe that is asking a bit much. I am going with the majority review being 3 months! As a matter of record, after the first 3 months on Humira, I felt much better!

[@lavitra.]

Hello, can you update us on how it's been working for you?

[@SkySweetie]

Would you mind updating?

[@uresla6321]

Can update your experience now please

[@reneemartel8802]

I've been on hadmila started in November.. it's making me fat.

[@timlee4527]

I take humira. The injection site is zero,,,the pain is non existent. My experience

[@rahulchoudhary8295]

Who many years you take

[@MA-xd9zl]

I wish it was like that with me, always swelled on site and very painful, stoped taking a year ago

[@RJ67.]

@@MA-xd9zl did it help at.all

[@MA-xd9zl]

@@RJ67. I took to help my inflammation go away, after a year it got smaller but the doctor said not enough and changed me to stelara. Stelara was horrible for me, didn’t help at all and the side effects were worse than my crohn. Because of that I stoped taking in March.

[@donnamontanarella2403]

I have been on Humira for about 3 months for Crohn's Disease. It has caused severe nausea and problems with my tendons getting swollen and sore. My body pains out of control.have been I have been feeling terrible with no improvement in any GI symptoms. I was put on Humira because I have another fistula. It took a while for me to figure out that it was the Humira causing my symptoms because I have fibromyalgia and other issues. I will never take it again!his last injection had the worst side effects. Even my Humira nurse was unaware of some of the side effects. Has anyone else had tendonitis or flu like symptoms? If so, how long did the symptoms last after the last shot? Did you do anything to treat it beside discontinuing the medication? Thank you in advance!

[@patriciabakewell712]

My 25 year old son has acute ulcerative colitis, dr has recommended this treatment and another med similar. Ive been researching and came across your story. Thank you for sharing. This is so confusing and scary. Hope you are feeling much better.

[@HopeinJesus1987]

I'm truly sorry this has been your experience. I hope you find the treatment that will help improve your quality of life. I just started Humira today, and I'm quite nervous 😓

[@donnamontanarella2403]

@@patriciabakewell712 I'm sorry I did not see your comment until now. Thank you for responding. I discontinued Humira 5 mo. ago. It's suppose to stay in your system for 5 mo. My Achilles tendon remains swollen, painful and has lumps on it. I was suppose to see a specialist but got Covid and had to reschedule. There is no improvement yet! I hope your son finds relief from his UC. It's so hard to have such devastating disease. Watching your child suffer is a living hell. I am so sorry you are both going through this. God bless you both!

[@donnamontanarella2403]

@@HopeinJesus1987 I sincerely hope that you get relief. Feel better dear.

[@HopeinJesus1987]

@@donnamontanarella2403 Thank you and you as well 🙏 ❤️

[@raleighamelia7895]

Took my first dose of enbrel a couple days ago. Was fine in the first day but then developed flu like symptoms. I had the flu a week or so before starting, so this is just great how it came back 😒 has anyone else experienced this? I’m hoping these symptoms go away within the week. I also work with 18 month-4 years old every day so it’s really not the best either when all of the kids r sick rn

[@mipimipi166]

How do uou manage on bilogical treatment?how long was the flue after the dose?

[@josephjames259]

I took Actemra for 10 years. Had to stop because my white cell count would drop.

[@stefanieaguilar6574]

Hi Joseph, please can you give me your number, so that I can contact you absurdo actmera. Please, thank you.

[@loridennis2989]

Yes, the medication DOES cause infection!

[@manicmandownup]

You’re a doctor? She said the medication makes it harder to fight off an infection…that’s well known with biologics.

[@jaxsage5767]

Am disappointed in Johns Hopkins. This video is far from being the best instructive video. Not mention of the manner in which to squeeze and hold the skin and the need for the injection to be at a 45º angle. What about the option of allowing the medication to sit for 20 minutes to allow for it to warm after removing from the fridge? It would also be better to actually show a person injecting the Stelara after pointing out the best body locations for the injection.

[@jeffwolf8018]

Through a bunch of research I've done. I've determined that I am too sick to handle biological monoclonal antibodies. You need a certain amount of good health to be able to handle this stuff. Some of my conditions are brutal headaches, itchy, nearly zero appetite, full body rashes that I've been to many dermatologists for and every one of them has failed me. The only thing that seems to help reduce the rashes is organic coconut oil from the supermarket.. and I don't hesitate to go on top of my head all the way to my feet with this stuff.. then I have to hide from my dog because he'll try to lick me clean. And then there's the can't get out of bed zero energy or ambition weeks at a time. If not for months.. there was only one of them that worked a little bit and that was remicade. When I had a flare up on remicade and they put Imran on me on top of the remicade and that was the end of that it blew my whole body up into a rash that was so bad that at night time I didn't realize but I was scratching throughout the night to the point where I was bleeding everywhere in bed.. the worst areas are generally my shins my face forehead and around my eyes, however it's the entire body those are just the worst areas..

[@theodorekountouris4487]

Amazing the biological drugs i try Enbrel consetyx simphoni sulphazaline double edge swords are the side effects are or can be serious i get glucose 2,9 hypo early morning allergic reactions wizzing laryngitis aspergilosis " and high flare of psoriasis on my feet down, PSA high levels even thyroid cancer wow a coctail of events enjoy the ride

[@soysurreal]

I am very worried about my mom. Her medicine metrotexate has got her liver and lungs affected. Now doctors recommended biological drugs. Is there any natural medicine instead of all these, it just seems to get patients worst.

[@typsygypsy70]

@@soysurreal No.

[@shekharpatil8118]

@@soysurreal go for ayurveda treatment

[@donaldtenn8225]

@@soysurreal I believe and I have read several studies stating that Methotrexate does assist with biologic medicines. I was hesitant to use methotrexate when my wife and i were planning to have a child but tried it afterwards and I did suffer adverse effects and had to quit. I have heard and read both good and bad about Methotrexate, I am of the belief that it is a necessary evil. BEST TO YOU AND YOUR MUM!

[@evanchornaby1280]

@@donaldtenn8225 Agreed life is incredibly unfair sometimes

[@tedteddy1802]

Wow