Sjögren Syndrome - Dry eyes, Dry mouth, Arthritis - Rheumatology Series

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Sjögren Syndrome is an autoimmune systemic disease.
Sjögren syndrome is a clinical triad of dry eyes, dry mouth and arthritis.
Sicca syndrome is dry eyes, and dry mouth, but NO arthritis.
Symptoms of Sjögren (Sjogren) syndrome include dry eyes (xeroophthalmia), dry mouth (xerostomia), arthritis, dry skin (xerosis cutis), dry vagina, painful intercourse (dyspareunia), autoimmune thyroiditis, monoclonal gammopathy, lymphoma (usually marginal zone lymphoma, aka MALToma which is a B-cell Non-Hodgkin's lymphoma).
Sjögren Syndrome affects the minor salivary glands, the lacrimal glands, the lymph nodes, the thyroid glands, the vaginal lubrication glands, the sebaceous glands,...etc.
Sjögren syndrome serum antibodies include anti-SS-A (Anti-Ro) and Anti-SS-B (anti-La).
Sjögren Syndrome is an autoimmune disease characterized by the presence of autoantibodies that attack the salivary glands (causing dry mouth or xerostomia), the lacrimal glands (causing dry eyes aka xerophthalmia or keratoconjunctivitis Sicca), and the joints (causing an inflammatory arthritis).
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Sjögren Syndrome is an autoimmune disease characterized by the presence of autoantibodies that attack the salivary glands (causing dry mouth or xerostomia), the lacrimal glands (causing dry eyes aka xerophthalmia or keratoconjunctivitis Sicca), and the joints (causing an inflammatory arthritis).
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[@MedicomaMedLecturesOnline]

You really have inspired me man!!!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@imcrazyforwar]

I just got diagnosed with this shit, and it's mildly infuriating that it took years to get a diagnosis. I had so many doctors I saw tell me "maybe lose weight and you'll stop feeling this way and all your symptoms will go away" instead of just ordering the test. it's one of the reasons I'm in medical school, well pre-med right now, so that somebody else doesn't have to deal with that same thing and get some actual answers.

[@MedicosisPerfectionalis]

I wish you all the success in the world!

[@imcrazyforwar]

@@MedicosisPerfectionalis and thank you for making these videos, it helps break down and teach all of these subject into an easy and sometimes funny way to understand. Thank you for doing these

[@MedicosisPerfectionalis]

The pleasure is all mine!

[@charki40]

I have sjogrens and RA that has progressed and is painful but I could not stop laughing at your entertaining and highly informative video. Thank you : )

[@ultraviolent1914]

I hope you get well soon sir

[@mewena9998]

I hardly comment on videos but I have to say THANK YOU FOR THIS CHANNEL. As a medical student with visual memory and the need to understand what I learn, I am deeply deeply grateful to have found your videos.

[@MedicosisPerfectionalis]

I am honored!

[@jaehokim9266]

My man said "shutup! i got chu~". LOL. Pure comedy. Amazing videos. Literally this is perfectionalis explanation, bravo. And lastly, don't listen to the haters, my Egyptian brother. Stay strong, carry on.

[@MedicosisPerfectionalis]

Thank you so much 😊

[@Supsup516]

Getting case 3 asap made me want to watch more!! YOU ARE A LEGEND FOR THES VIDS!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@jenny64342]

you said strongly negative birefringent, bt marked on strongly positive birefringent for gout...I didn't get it

[@MedicosisPerfectionalis]

Gout is strongly negative, Pseudogout is weakly positive.

[@Sammy.a1287]

He made a lil mistake

[@mercyz6252]

Amazing teacher!!! God bless you abundantly!

[@MedicosisPerfectionalis]

Thank you so much 😊

[@preciousmene1736]

Lmfao, if you are a mediocre student you'll memorize the triad and if you are a superb medical student you will memorize the octagon. I feel low-key manipulated. We move regardless. Thank you so much for these amazing videos. Enjoying them all the way from South Africa.

[@MedicosisPerfectionalis]

Thank you so much! I appreciate you!

[@maryamjavaid]

13:57 periodontal = periodontium = supporting structure of the tooth = gingiva+alveolar bone+ ligaments(pdl)+cementum. :D

[@ThatsWhy-]

How would you relate between Sjögren and its effects on polyurea, polydipsia, insipidus diabetes and/or aldosteron? Explain the connected dots...

[@hxcjessikaa]

Thank you for doing this video , I have Sjögren’s syndrome 🙋🏻‍♀️

[@MedicosisPerfectionalis]

Oh! I am so sorry to hear that!

[@hxcjessikaa]

Medicosis Perfectionalis it’s OK I’m learning to live with it thanks for doing these informative videos!

[@msblaze3516]

I have it also

[@Voop12345]

Sjrogen is not that bad in real life. Most of patients have a normal life (I have Sjrogen for more than 17 years) and my eyes are severely dry but with OTC tears drop I'll get back to normal...😁 no need to be sorry

[@kateskeys]

👍🏼👍👍🏽👍🏿🌟🌟🌟Im no where near the medical field -but I love these videos. I learn a lot and love the humor. THANKS!

[@MedicosisPerfectionalis]

My pleasure!

[@loayibrahim1855]

you said that CPPD has weakly positive birefringent and gout has strongly positive.but when I was studying rheumatology from USMLE books they say gout has negative birefringent and CPPD has positive birefringent ????

[@MedicosisPerfectionalis]

Gout is strongly negative...Pseudogout is weakly positive.

[@MedicomaMedLecturesOnline]

Another Great video!!! Medicosis perfectionalis you rock!!!!

[@miracduruk1034]

Thanks a lot for your videos Dr. I benefit from your videos a lot.

[@MedicosisPerfectionalis]

My pleasure 😇

[@JosePerez-xv8im]

As always, great work

[@MedicosisPerfectionalis]

Thank you!

[@eroconka92]

Like wtf...this is art 😍 11/10

[@MedicosisPerfectionalis]

Thank you ☺️

[@ashabalam1425]

Nice lecture

[@MedicosisPerfectionalis]

Thank you so much!

[@doctorbase2364]

hi medicosis guy , i have a qst when talking about SS do we have monoclonal or polyclonal hypergammaglobulnemia and why ?? pls answer in comments not on ur videos and thankkk u sooooooooooooooooooooo much ur the best !

[@demekeeligo64]

best teacher ever

[@MedicosisPerfectionalis]

Thank you 😊

[@pratikshamishra1820]

medicine is fun...when I learn from ur videos.....keep it up. Love from India😍❤

[@MedicosisPerfectionalis]

Thank you 😊

[@elizabethv7411]

Amazing teacher

[@MedicosisPerfectionalis]

I am honored!

[@javiercb100]

GOD OF MEDICINE ...... YOU ARE JUST AMAZING

[@MedicosisPerfectionalis]

Thank you 🙏

[@sarahalfurais5394]

Amazing, thank you so much

[@MedicosisPerfectionalis]

Sarah Alfurais You’re very welcome 😊

[@mohrma]

Very informative video. Thanks for you.

[@MedicosisPerfectionalis]

My pleasure 😇

[@mohrma]

@@MedicosisPerfectionalis I am Arheumatologist and I have interested so much in your videos, you made it very easy and lovely, so please we need more new videos about the rheumatic diseases. With my best regards.

[@deepwithin6517]

AlhamduliAllah Thank you

[@مروةمحمد-ع9ي9ج]

Great educational video.

[@MedicosisPerfectionalis]

Thank you 🙏

[@NICHOLASGAMER007]

Isn’t it type 2 hypersensitivity ?

[@knightmist3971]

3:55 I guess I'm not the only one who knows the right answer but still highlights the wrong one

[@rekhakadam6393]

Thank you!!!! 😊.

[@nadafares6164]

Amazing!! 💚💚💚💚💚💚

[@MedicosisPerfectionalis]

Thank you!!

[@sahilkhatri541]

Title should be Freakin Sjogrens syndrome Btw video was great..

[@MedicosisPerfectionalis]

Haha 😂

[@abbybluemusic]

i've seen a vlog of a Swedish woman here on yt who has Sjörgen and shares her thoughts on it, it was so sad to see her unhappy in some vids :с

[@MedicomaMedLecturesOnline]

😭 I think i have watched her vlogs!!

[@MedicosisPerfectionalis]

I am so sorry to hear that! Autoimmune diseases are really bad!

[@sevval2544]

thank you very very much..

[@MedicosisPerfectionalis]

You are most welcome!

[@whatsonmymind4848]

I have a question: When I wake up in the morning I have a dry throat and mouth, my hands are swollen and sweaty, I’m not rested at all and my joints hurt as hell and I’m extremely stiff. Also my eyes are dry and hurt. However the dryness goes away over the day when I drink something, only the swollen hands and joint pain stays and fluctuate. What do you guys think? I’m so clueless and I hate going to sleep... since I wake up in so much pain...help

[@stfu7308]

So did you get the doctor to check it out?

[@guptamala5]

Same here

[@هاجرأميرحمدي]

You are a great teacher

[@MedicosisPerfectionalis]

Thank you 🙏

[@asmaaadel4321]

Promising 👏

[@محمداحمدعطيهجوده]

Please complete the seris

[@MedicosisPerfectionalis]

I will!

[@محمداحمدعطيهجوده]

@@MedicosisPerfectionalis all love

[@sihamreguemali5358]

ماهو اسم المرض بالعربي وشكرا

[@MedicosisPerfectionalis]

متلازمة شوجرن.

[@زينبالربيعي-ذ7ج]

My profesor uses primary and secondary classification 😂😂😂😂😂

[@MedicosisPerfectionalis]

Haha 😂 It’s ok!

[@b2650]

Actually gout is strongly NEGATIVE birefringent not positive

[@MedicosisPerfectionalis]

True! Gout is strongly negative…Pseudogout is weakly positive.

[@samyu3130]

gout is negatively birefringent

[@MedicosisPerfectionalis]

Yup

[@danielgoldsmith9755]

Super fast but really educational and entertaining.

[@nidhaan3752]

Even my self suffering frm sjhogrns syndrome

[@Sarah-og1rq]

Freakin gud 👍

[@MedicosisPerfectionalis]

Thank you 🙏

[@samanthatrussell476]

Can you please be my doctor? haha

[@kashifali-ec7fr]

U r ♥️

[@MedicosisPerfectionalis]

Thank you so much 😊

[@ericabrown4838]

🤣🤣🤣 @ Shut up

[@MedicosisPerfectionalis]

:)

[@OOOOOOOKKKKKKK69]

Auto immune disease is more common in females. This man saved me hours of studying :-)

[@MedicosisPerfectionalis]

Wow 🤩 I am happy to hear that! Moreover, immunodeficiency diseases are more common in males.