Scleroderma (Systemic Sclerosis) - Signs, Symptoms, Pathophysiology - Rheumatology

Scleroderma (Systemic Sclerosis) | Learn the Basics.
Scleroderma (Systemic Sclerosis) is a condition characterized by skin thickening, hardening, Raynaud's phenomenon, esophageal dysmotility, bilateral interstitial lung fibrosis,...etc.
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[@MedicosisPerfectionalis]

🧪🥵😰Acid-Base Course: www.medicosisperfectionalis.com/products/p/acid-base-disturbances-course/

[@ayattaher3728]

"The type of education you have recieved" is what made you who you are today.Egypt's healthcare system is totally messed up for sure, yet the thing I'm quite sure of is that Egypt has amazing, brilliant, and experienced professors that I am proud that I have been taught by them, and will never deny the value of the information they gave me wherever I completed my postgrads, they will always be a reason for who I am !

[@hippiemama41]

I was diagnosed with systemic sclerosis w/ ILD in Dec 2019, at 37yr. I found your channel today and I only wish I found it early. Thank you for all the information you provide as it helps me and many other's like me understand our diagnosis more.

[@MedicosisPerfectionalis]

Thank you 🙏 I wish you the best of luck!

[@nicolevintagepigeon6313]

I found your channel while going through the rheumatology work up last year. That playlist has been a GOD send!! 1 year later, you make the video of my diagnosis💜💜you are literally the greatest medical channel EVER💜💜

[@MedicosisPerfectionalis]

Wow 🤩 It’s such an honor to be able to help you! Thank you so much! Good luck 🍀 and stay strong! Anytime you have any questions, please let me know!

[@nicolevintagepigeon6313]

I’m back again because I have heart involvement that my local hospital had no clue about. Please future medical professionals: don’t ignore invisible illnesses. Tons of us are suffering while progressing to the point that people may ever notice. Going to any medical setting not specializing in my people is often tesunatixing

[@khdr4165]

Oh finally😁❤ actually i haven't asked you yet about the rest of rheumatology playlist but honestly i was gonna ask you haha. Because the other day i had to look up through the whole youtube for Osteoporosis and Osteomalcia and these stuff, and wasn't statisfied cuz i only enjoy your videos seeiously! Thanks alot❤

[@MedicosisPerfectionalis]

You’re very welcome, my dear!

[@stanislavas4720]

It’s a shame that I can only leave one like. This was a masterpiece of a lecture!😂👏

[@MedicosisPerfectionalis]

Thank you so much!

[@SassyO100]

I’m very early in my Sclerderma journey. I’m at the stage of suspected SSc due to having more blood investigation done. It’s been a long road to get to Rheumatology. I’m just researching to get insight into how I can make early lifestyle changes to help myself. Thank you for educating us.

[@MedicosisPerfectionalis]

I wish you all the best!

[@ghufran9479]

إبداع بحق 👏شكرا دكتور فعلا انت فخر للعرب تحية لك من العراق 🇮🇶

[@MedicosisPerfectionalis]

🙏🙏🙏

[@someonenotyou]

I used to watch Netflix during my study breaks, now I just watch your videos. haha please make a podcast! #productivity

[@MedicosisPerfectionalis]

Haha 😂 Wow 🤩...Thank you! I will give it a thought!

[@elmagnifico2022]

almost every topic can be found here,really!!! thank you🌌🌌🌌

[@MedicosisPerfectionalis]

My pleasure 😇

[@oshyobass8678]

مشالله تبارك الله ربي يحفظك ابداع ...في ميزان حسناتك انا ندعيلك في ضهر الغيب ويشهد الله اني في امس الحاجه للعلم ومعنديش مقدره ماليه لكن انت سهلت عليا اسئل الله ان يجعل علمك شفيعا لك في الاخره وعني انا جزاك الله كل الخير

[@MedicosisPerfectionalis]

🙏

[@gustavoluizon1528]

Terrific!! Amazing video, thank you!

[@MedicosisPerfectionalis]

My pleasure 😇

[@HenHousegirl.1]

And I’m really happy that you said we had a mask like face, nice dude!!!

[@michelenichele294]

I’ve suffered from Raynaud’s for the past 50 years, at least, and always referred to it as the “red, white, and blue disease.” Even though I was born in Paris, I became a U.S. citizen at age 15. Just wanted to say, though, the French describe their flag 🇫🇷 as “blue, blanc, rouge.” (Blue being the color closest to the flagpole.) But, as a proud American 🇺🇸, Raynaud’s will always be the “red, white, and blue” disease to me. P.S.: your work is spectaculaire!👏🏻🙏

[@MedicosisPerfectionalis]

Thank you, Michele!

[@sakshipandey1711]

i was about to sleep but now i am even more excited to study for my test. thankssss. I loved your humor level ;)

[@MedicosisPerfectionalis]

Thank you 🙏 Good luck 🍀

[@rokiaamr4312]

Bro really thank you so much you are freaking amazing your unique way is very interesting I escape from my pooring college lectures to your pretty ones u always make it simple abs easy 💜💜🥺I owe to you too much I ma really very grateful for your presence all love from Egypt..

[@MedicosisPerfectionalis]

Thank you so much 😊

[@karinapertiz7815]

I need you to make videos explaining everything about everything, 'cause man, you're great, thank you for your hard work. Greetings from México 💚🤍❤ I love your videos!

[@miahender7991]

Nicely done and summarized! That saved us reading million of years in the book hahaha BUT what is the answer for the question??? diferential dagnosis with mask-like fascies?

[@DoctorsHub]

Nicely explained everything about scleroderma.

[@MedicosisPerfectionalis]

Thank you 🙏

[@demekeeligo64]

I love the way you teach. Thank you

[@MedicosisPerfectionalis]

My pleasure 😇

[@sakthipriyakurmapu9383]

People can crack any entrance exam with clear concepts conveyed by you, Sir! Love your sense of humour, btw!!

[@MedicosisPerfectionalis]

Thank you so much 😊 Would you please help me by sharing?

[@sakthipriyakurmapu9383]

@@MedicosisPerfectionalis Definitely, Sir.

[@army-dp8nj]

مصر فخورة بيك يا دكتور شكرا خالص

[@MedicosisPerfectionalis]

Thank you 🙏

[@Sowhat29]

دا دكتور مصري! فخر العرب أقسم بالله 😭😭😭😂😂😂😂🔥🔥

[@MedicosisPerfectionalis]

Thank you 🙏

[@esraaabdel_shakoor6609]

استحالة يكون مصري 😂😂😂😂😂😂

[@MedicosisPerfectionalis]

أنا مصري وبابا مصري 🇪🇬 يا دكتورة إسراء 😊

[@foodiesworldUSA]

I have a q on this topic .. I saw someone posted on usmle forum that what is the annual screening for someone coming in with digital ulceration and have SS?

[@dartajamul7846]

Again ist view... Thanks buddy for such a beautiful playlist. 💝💝

[@MedicosisPerfectionalis]

Wow 🤩 You're such a nice person!

[@muhammadahmad1251]

U r requested plz to make a video in SLE

[@mennak113]

Really fantastic !big thanks

[@MedicosisPerfectionalis]

My pleasure, Menna! Would you please help me by sharing?

[@DrMnike-]

Great video! My mother died because of renal complications of Systemic Scleroderma 20 years ago

[@MedicosisPerfectionalis]

I am so sorry! My condolences!

[@ranacottage5764]

My father too died because of scleroderma

[@ayattaher3728]

And I have a question. since ACE inhibitors are C/I in CKD or renal artery stenosis since in vasoconstricts the renal affrent arteriole, how does ACE inhibitors work for scleroderma since it involves a pathophysiology similar to renal artery stenosis (pre-renal).

[@nikita8294]

you're the only one who can make me want to study when i'm burnt out and get nauseous after opening a book

[@MedicosisPerfectionalis]

Wow 🤩 I am honored!

[@chriswagner7857]

This video was very different. I don't know why, it seemed like you were jumping around quite a bit but. Thank you for the content.

[@MedicosisPerfectionalis]

Thank you so much for your honest feedback! It’s just an intro...More scleroderma videos are coming soon.

[@amineaboutalib]

@@MedicosisPerfectionalis I LOOOOVE THIS WAY OF TEACHING

[@lillyrocks2011]

It's a shame there's any medication yet against the extra collagen production. I hope scientists can find something against it, it's one of the most terrible thing that happens with this awful disease.

[@isacontreras3399]

WOWW THANK YOUU

[@MedicosisPerfectionalis]

My pleasure 😇

[@user-tz1zr6kh9k]

You are the best🖤

[@MedicosisPerfectionalis]

Thank you 🙏

[@samajbhanproduction1520]

What is the solution please tell me medication my mother has systemic sclerosis she can't even handle a glass of water wrist doesn't close

[@zainabmahdy3551]

Wonderful ✨

[@MedicosisPerfectionalis]

Thank you 🙏

[@MAHMOUDALHAJALI]

good job.... thank you

[@MedicosisPerfectionalis]

My pleasure 😇

[@MAHMOUDALHAJALI]

@@MedicosisPerfectionalis Case 1: The 32-year-old patient is evaluated for fatigue and low fever (started 8 weeks ago), which associates with edema and pain in the joints of the hands. bilaterally, accompanied by morning sickness (about 2 hours). In the last 2 weeks, he received treatment with Naproxen, with the improvement of symptoms. In the last week, leg edema appeared and he gained 4.5 kg in weight. During the physical examination: BP=152/96 mmHg, malar rash, pain and edema in the joints of the hands, and calf edema that leaves a well. Biological: ESR = 88 mm/h, hematocrit 38%, complement (C3, C4 low), creatinine 1.1 mg/dI, ANA high titer (1/320), positive anti-Sm, and anti-dcDNA antibodies. Urine examination: protein +**, red blood cells = 0, Leukocytes = 0. Proteinuria = 4 g/24h What is the next diagnostic step? A. Antiphospholipid needle dosage B. CT abdomen and pelvis C. Renal biopsy D. Renal arteriography E. Electrophoresis of serum and urinary proteins what do you think? should be a renal biopsy to confirm the nephrotic syndrome I am lost and l have a rheumatology exam next week :)

[@karanmishra3761]

I think ESR is low in Scleroderma ?

[@Aiman3471]

I guess Raynaud’s phenomenon is not the initial finding in “diffuse” scleroderma

[@nicolevintagepigeon6313]

I’m dying....”romance novel”💜💜😂😂😂😂

[@MedicosisPerfectionalis]

Haha 😂

[@sunilshevkani6652]

Coz of quality content generated from guys like you, the chaotic web 2.0 made some sense to content consumers like myself.. I wish 3.0 coupled with AI/ML will give you more space and wings.. Humbled!

[@MedicosisPerfectionalis]

Haha 😂 Thank you 😊

[@kb5654]

I can’t deal with the silliness of such a serious disease. Especially since IVE BEEN DIAGNOSED

[@HenHousegirl.1]

My thoughts exactly!!!

[@rehambakkar2861]

Big like before watching But;when will you continue your rheumatology playlist?? 😄😄

[@MedicosisPerfectionalis]

Haha 😂

[@litanysttar4653]

So amusing thx 😂❤

[@MedicosisPerfectionalis]

My pleasure!

[@hibaaldubaai5140]

You are amazing

[@MedicosisPerfectionalis]

Thank you!

[@RebeccaSong]

I’m super offended that you drew a picture of me. 😭 (diagnosed with diffused systemic scleroderma at 11 years old aka as my doctor likes to say “the most severe form of scleroderma” he’s seen. I need a new doc lol)

[@fatmamohammed6924]

Impressive 👏👏👏 proud to be Egyptian 👌👌👌💪💪💪

[@MedicosisPerfectionalis]

Thank you 🙏

[@F9oo9h]

You should be .. what a great nation ❤

[@theJenhha99]

Limited is systemic. It is the updated name for CREST

[@ThatsWhy-]

I like it *

[@Allpmpjkdmmp]

Scleroderma cannot make the skin as it was before, can it be light and thin ???

[@mdam1543]

"get your head out of your sigmoid" 😭 I'm gonna use this from now

[@MedicosisPerfectionalis]

Haha 😂

[@dr-nouran-a7med.]

you have CT 🙂I can swear you are egyption pro😂😂😂😂 مش عارفه هتفهم العربي ولا لا بس عاش يا دكترة الشرح حلو جدا 👏👏

[@MedicosisPerfectionalis]

🙏🙏🙏

[@mahmoudahmed-hf6mb]

dude I swear ur a legend and I utterly got stonished when i found out that ur Egyptian

[@MedicosisPerfectionalis]

حبيبي يا دَكترَه 😊

[@coremanishmehta]

Crest syndrome.. first question should be limited system sclerosis.. I guess!

[@Dr_Sri_Harsha_Guthikonda]

the prof. story!!! hehe....that's too familiar!

[@MedicosisPerfectionalis]

;)

[@RebeccaSong]

“freaking scleroderma” 🤣

[@MedicosisPerfectionalis]

:)

[@rahuldmello9668]

Was that education in Germany by any chance?

[@MedicosisPerfectionalis]

What do you mean?

[@rahuldmello9668]

@@MedicosisPerfectionalis Sorry, for some reason I thought you were German. My bad. :)

[@OriginalJayden]

My mom has this, she isnt going to live long anymore

[@fabulosa002]

10/10

[@MedicosisPerfectionalis]

Thank you 🙏

[@audreyroberts3607]

Why he sound like robin Williams accent in mrs. Doubtfire ? Lol

[@razanathamneh7906]

perfect explanation ,But i'm confused now , in toronto notes and uworld question's note , they said that scleroderma is a non-inflammatory autoimmune disease , while in this video and on google they say it is an inflammatory condition ! is there something that i miss or can't understand ? Thanks in advance

[@hdh2179]

amazingg

[@MedicosisPerfectionalis]

Thank you 😊

[@saeedrkhan1372]

Ur good name teacher

[@MedicosisPerfectionalis]

Thank you!

[@johnmarston8532]

What did you say that velcore...... Rattles of death

[@MedicosisPerfectionalis]

The word rales came from an old French term: “Rales de la mort”...which means “rattles of death.”

[@johnmarston8532]

@@MedicosisPerfectionalis oh thanks bro...

[@amineaboutalib]

I think that you meant that one of the most common side effects of paracetamol are headaches

[@RFN871]

❤️

[@MedicosisPerfectionalis]

Thank you 😊

[@sandrakomatt3642]

Man😂😂😂... I love you... 🤣🤣🤣

[@MedicosisPerfectionalis]

Thank you 😊

[@hannahrosa5485]

You're hilarious. Killer accent. Ya. I'm back, poor you.

[@HenHousegirl.1]

The way you describe everything is totally insensitive to people who actually have scleroderma. The whole time I was listening to you I was thinking geez guy, could you please try to think about what you are saying? It was almost like you were making fun of us or using it as a joke! Not funny. I do have interstitial lung disease, I do have lines around my lips, I do have the shiny skin, all of which you joked about! Thanks, nice job….

[@user-oc3gd7ob9s]

Making fun of a life threatening desease is not funny.

[@mocn192]

Wow 0

[@MedicosisPerfectionalis]

Thank you!

[@mixinitupNY]

✔️👨🏻‍⚕️✔️🤪

[@MedicosisPerfectionalis]

Haha 😂

[@jesustsan]

😂😂

[@MedicosisPerfectionalis]

:)

[@roseuj]

Friend died within 2 years.

[@MedicosisPerfectionalis]

I am sorry!

[@mayalqahtani1184]

@@MedicosisPerfectionalis r u from Egypt?

[@muzamilmehmood3195]

Mask like faces PARKINSON'S DISEASE MYOTONIC DYSTROPHY SS

[@sberznji]

Could be .depression . Schizophrenia