Smooth Muscle Contraction | Excitation Contraction Coupling | Nerve Muscle Physiology

✨This is my best attempt at simplifying how smooth muscle contracts and relaxes. I talk about the different ways calcium enters the cell, the steps of contraction and relaxation and a little bit about some of the special features. I hope it helps! ☀️
🌟What's in this video?
0:00 - Intro
0:09 - Skeletal Muscle Recap
2:02 - Smooth Muscle Calcium Entry
6:51 - Smooth Muscle Contraction
9:10 - Smooth Muscle Relaxation
10:05- Special Features (Latch-Bridges, Stress Relaxation)
11:16 - Regulation of contraction
✨ Other videos you may need:
🔅Structure of Smooth Muscle : • Structure of Smooth Mu...
🔅Structure of Skeletal Muscle: • Structure of Skeletal ...
🔅Structure of a Sarcomere: • Structure of a Sarcome...
🔅Neuromuscular Junction: • Neuromuscular Junction...
🔅Nerve-Muscle Physiology :
• Nerve & Muscle Physiology
💫 For more videos like this, subscribe to my channel!
Byte Size Med: / @bytesizemed
📚Factual References & for Further Reading:
- Guyton and Hall Textbook of Medical Physiology
- Ganong’s Review of Medical Physiology
- Boron and Boulpaep Medical Physiology
- Costanzo’s Textbook of Physiology
- Openstax Anatomy and Physiology
openstax.org/details/books/an...
- Openstax Biology
openstax.org/details/books/bi...
(The last two are links to open-source references. They are NOT affiliate links)
🌤 Note:
These are just a collection of my notes. So use them the way you would use borrowed notes from a friend. 📝
The images in this video are hand-drawn for illustration and explanation only.✍️ Hence, they may not be anatomically accurate. I am just one person making these videos. If there are any errors, that is unintentional. I try super hard to avoid them. Please let me know if you find any, so it gets clarified for other viewers. Science constantly evolves and changes. New discoveries are made everyday. So some of the information in these videos may become outdated. If you notice that, please let me know so I can update them.
⚡️Disclaimer:
These videos are NOT a substitute for a medical textbook. Textbooks are written by experts (which I do not claim to be), edited, proofread and referenced. Please use them.
The information has been sourced from multiple references as mentioned above. I draw all the pictures myself. But if I have inadvertently infringed on any copyright, that is completely unintentional. I only make these videos to impart education. If I have accidentally violated copyright in any way, do let me know so I can make the necessary changes or give credit to anyone who is owed the same.
These videos are NOT intended for patient education. They are NOT a substitute for diagnosis and treatment by a licensed medical professional. Always seek the advice of a qualified health care provider for any questions you may have regarding any medical condition, so that they can address your individual needs.
🔅They are ONLY meant to help students of medicine and health sciences with studying, and should be used for just that purpose and absolutely nothing else.
Byte Size Med. All Rights Reserved.

[@aryamantalwar2913]

Thank you so much!! You might or might not realise but never have I ever seen such a video with this level of simple and lucid explanation on physiology. Please keep up the good work. God bless you!!

[@hazin67597]

Have watched so many videos on KZbin none of them has been so precise and concise as yours.

[@fluxgrots]

Great video, though a think a clarification regarding skeletal muscle contraction is needed: The breaking down of ATP is not directly coupled to the power stroke. Rather, the ATP-ase activity of the myosin head occurs before contraction, cocking the myosin head back like a spring. When the myosin head combines with actin, the already cleaved ADP+phosphate ion is released and the energy that came from breakdown of ATP is released in the power stroke.

[@ShreeyaSirulu5]

Thanks for uploading these lectures You’re covering each and every point in a very less time period 😊

[@keyvampni7427]

I can't believe I spend two days trying to figure out how this works. Honestly I only clicked on the video cause I thought "Might as well procrastinate in a way that makes me think I am learning for the exam" You managed to get me to understand a for me really confusing topic in 12 min. And with visuals that are not trying to confuse me but actually are showing just as much as I need to understand without being too rudimentary. And all the while it didn't simplify so much it got unusable to me but also neither did you try and make everything sound overly complicated. Thanks a lot!

[@bytesizemed]

Thank you! I’m so happy to hear that it helped you!😊

[@wanmohdnaimwanmohdruslan642]

Thank you! Really clear demarcation between skeletal and smooth muscle contraction

[@sachchidanandwattamwar1237]

Great, honesty, sincerity and genuinity of teacher always reciprocated by adorability though people referring to it as a, " skill " 🙏🏻🙏🏻thanks

[@ekenmauma7053]

Please write it here

[@tiratira9409]

you are best medicine lessons channel so far . This really helped me so much i took hours to figure this out

[@chinisoli2849]

OMG I was waiting for a video on this topic for soo long! Thank you so much 💜

[@poopsikins5779]

Love it. Clear, concise, yet has the required depth.

[@mirriammwenda3678]

You are really of great help! This has been my savior channel this semester ☺️❤️❤️ thank you so so much!!❤

[@richaiajankie3454]

This made this the contraction of smooth muscle crystal clear for me. Thank you

[@lynnmungai]

Lovely content

[@mosesraja1976]

I was literally searching for this video ….and I am extremely satisfied…thanks a lot ❤

[@catherinehubbard1382]

This was extremely helpful, thank you!

[@10SoccerCrazy]

I don't understand how u are able to make this topic so simple.. god damm.. you are great, Byte Size Med!! thank you! :)

[@matsuko981]

It was a really a great explanation. Thanks for the hard work.

[@anamihalache8312]

Thank you for your work!!!! Keep going!!❤❤

[@jessynyirongo4672]

Thank you so much for this clear explanation

[@isamaemmanuella8052]

It really was, thank you ❤️

[@kizzamoses8095]

I now understand these things thanks so much

[@aaronkabwe3773]

Thank you so much my great professor

[@Shahi7Khan]

Mam I m Not Sure Whether I can Say this Or Not But After Watching This Vedio I must say That I Just Love you 🤣

[@banyllarymbai6507]

thank you sm 💖

[@Cheeruppy6166]

thank you it was really helpful

[@josetrujillo738]

Great video

[@angadminhas3002]

The best out there 🙌🏻

[@soujanya1119]

Perfect video tht I needed thankyou🤍

[@iammanojnarayan]

Thank you 🥰🥰🥰

[@ka1ser66]

this helped me to pass my exam about muscles

[@eir_study6941]

This actually helped me in cramming for my SGD thank you T-T

[@Dr_Rajesh_JIPMER]

Thank you so much ma'am ❤❤

[@jawariyafatima2405]

It was really good

[@NehalChauhan-sh6wr]

Awesome

[@Abdulrahman-lp7dz]

you are a legend

[@pikapanda2255]

Clear explanations waiting for more videos specially in GIT

[@DrWOF]

6:48 "in addition to the replenishing the stores, the calcium in the *sarcoplasm* also rises." Sorry if this is obvious, but she meant to say *cytoplasm*.

[@user-de1qv5qs9q]

Amazing video

[@rabiasaleh1683]

a great vedio really.

[@himanshu8362]

Doing amazing, fabulous, fantastic 😍 work. I have never such a nice explaination....thanks a lot

[@bytesizemed]

Thank you😊

[@user-mm5gj1tk3n]

Great video!!! May I ask a question that if there are any calcium ions released from the mitochondria? Is the mechanism of it as same as that from SR? Thanks a lot!!!😍

[@MIMH92]

Thank you for the informative video. Does that mean reducing calcium allows smooth muscles to relax? I'm trying to understand sphincter of oddi dysfunction in which the sphincter spasms and can't relax to release the bile

[@joyaljosephjojo9082]

Top video

[@abhaykairati7067]

Very good explantion please make same vedio on cardiac muscle alo

[@Lyl22-ux8og]

Thank you so much ❤ Could you tell me what is the app that you use it, please!❤

[@irenehanna9260]

No words to say , this is amazing

[@bytesizemed]

Thank you😊

[@bio366geethasankar7]

😊🙏🙏

[@aasemahsan]

IP3 Calponin Myosin Light Chain Kinase Latch-bridges

[@bhadran04jmmc]

❤

[@kwameboyesomuah1386]

So does this mean calmodulin and Mlck is not in involved in the contraction of skeletal muscles

[@easy-peasy9906]

12:03 how is myosin phosphorylation and dephosphorylation Calcium independent mechanism when both the enzymes are activatedby calcium+calmodulin complex ? Plz throw some light on it

[@ST-tp4xr]

I noticed there was no mention of Caldesmon?

[@shraddhasingh8207]

how you made this video..is it ppt?

[@davidmosesansumana]

It's only God 🙏 will bless you.

[@bio366geethasankar7]

🙏🙏🙏🙏🙏🙏

[@davidmosesansumana]

Can u please direct me to a better explanatory Anatomy channel like yours🥺😩

[@zcetin755]

You are the best of the best with no discussion,thanks!!🤍

[@bytesizemed]

Thank you😊