Smooth Muscle

[@bayyoonful]

from all the way in the middle east, precisely Jordan, I want to thank you with all my heart! you helped me through my second physiology exam and now tomorrow is the final one< thank you so much!

[@alyaman81]

here the same story 😂😂😂

[@ginger4289]

Unlike cardiac or skeletal muscle, smooth muscle is not striated because it does not consist of sarcomeres. Instead, a network of different filaments are found throughout the entire cell body and this helps the cell contract. The three types of filaments are thin filaments, thick filaments and intermediate filaments. Thin filaments are usually connected to regions called dense bodies while the thick filament is found in between thin filaments. The movement of the thick and thin filaments causes the dense bodies to move together, which in turn pulls on the intermediate filaments, which brings all the dense bodies inside the cell closer together. This ultimately causes the cell to shrink and this is known as the muscle contraction. Smooth muscles can be arranged into two ways. We have single-unit smooth muscle, also known as visceral smooth muscle and we also have multi-unit smooth muscle. Single-unit smooth muscles consist of a collection of different smooth muscle cells that are connected via gap junctions. Only a few of these muscles are actually innervated by a neuron. When a signal arrives at the innervated smooth muscle, the gap junctions cause the other cells to contract in a uniform fashion. Therefore, single-unit smooth muscles contract together, as a single unit. These smooth muscles are also capable of myogenic activity. Multi-unit smooth muscle consist of a bundle of smooth muscle cells that are all innervated by a neuron. This means that the contraction of a muscle in a multi-unit system is independent of the contract of some adjacent cell. Smooth muscles are control by the autonomic nervous system and are found in places like blood vessels, stomach, small intestine, uterus, bladder and many other places. Smooth muscles are uninucleated, which means that they have one nucleus per cell.

[@maryam000002]

I don't know how but you always make things simpler and easier THANK YOU SO MUCH!!!

[@AKLECTURES]

The Mariam Thanks! :)

[@buckleyj44ify]

Thank you so much for your lectures, I study, read, re-watch my Professor's lecture and then defer to yours as back up and further foundation for my exams! I really appreciate your ability to clearly explain these extremely complex topics!!

[@andrewm2786]

"we have no way to control smooth muscle" *morning coffee has entered the chat*

[@jeremieerikssonlefebvre2647]

Thanks man, Ive watched a lot of lectures online. But I have to say you are a step ahead of all. You break it down very well and articulate everything nicely, which leaves no doubt for the viewer. Thanks again!

[@james4727]

You and the people over at crash course are the sole reason I am coping with a and p and bio xD thanks so much

[@shuvo265]

best lecture i have ever seen

[@dinisridamayanti4682]

thank you, your explanation is very clear. I want to ask permission to use this video to help my student understand the physiology of smooth muscle

[@hanifabdullah1992]

Beautifully explained. So understandable and clear.

[@paulklink2129]

Thank you for this video. It helped me out a bit.

[@gal304]

you are great! greetings from an Israeli student

[@AKLECTURES]

גל פ all the way from Israel! awesome! glad you liked the lecture! have a great one :)

[@ranaabaidulrehman4286]

You are making the topics easy for us👌🏻thank u for being so helpful for us. I really abhore the dislikers over here. Because these are the best presentations, even more than are delivered in our colleges 😊

[@hamoteinelalelei5152]

Thank you for this. Today is my test and man this helps alottt

[@bikram05]

Are you medico?

[@drastichaudhari]

Why are we paying the colleges? I should make my tuition payable to u!! Thanks for everything man!

[@RohanKumar-nj6bb]

🤣🤣🤣🤣🤣🤣🤣🤣

[@guswiens1597]

Thank you so much, it is so hard to find a video that explains well. Thank you

[@فاطمةقاسمعبدالباري]

الله يعطيك العافية خوية

[@luuchian2013]

The best lecture I've listened to. Thank you for all the detailed information :)

[@AKLECTURES]

chi an Luu Awesome to hear! You're welcome.

[@abdullahtown]

Fantastic explanation. Keep up the good work man

[@AKLECTURES]

Dula K Thanks! Will do :-)

[@shelllyshelly]

Desmin and vimentin are found in all muscles, as they are part of the mesenchymal origin, that's the only correction I would make, other than that amazin. I like your videos!

[@rasheedel-okka4427]

to be more specific desmin and vimentin is found in in vascular smooth muscles while desmin is only found in other normal smooth muscle cells like intestine :)

[@marwafayez8063]

very good lecture you make it easier thak you

[@mostafasalahel-din3683]

Thank you very much for your great efforts

[@emrekocoglu8546]

So much police sirens in your videos, I heard them several times in different ones, what's rly happening there? :D

[@maradelevingne6039]

So passionate. Much more informative than how my professor in General Physiology explains his lectures T--T Please be our professor lol. Thanks for this vid!

[@emilyvercammen2680]

Very helpful! You have beautiful handwriting!!

[@AKLECTURES]

Thanks Emily! :)

[@tranphuongtrang9594]

Hi. Why does a smooth muscle cell have only one nucleus?

[@Poshgirl26]

Thankyou for the video, and how does relaxation occur?

[@carlosvasconcelos4463]

Basically the amount of Ca+ is reduced. How? brack to ER or Out of the cell. Hope it helped :)

[@carlosvasconcelos4463]

Other way to achieve is also reducing P-Myosin

[@drseanyarkoni5267]

to be more specific, an enzyme called MLCP - myosine light chain phospatase induces the dissociation of myosine from actin.

[@hayfaashamer8258]

It is very good lecture , Thank you

[@trinityvong1037]

YOU ARE A LEGENDDDD!!!!

[@Youkimilosa]

Hi, I got a question. On smooth muscle cell thin filaments, do we find actine, tropomyosine and troponine? Does Calcium intervene in the same way than in skeletal and cardiac muscles? As there are no sarcomere structure, I was wondering about the other differences that can be seen. Thanks again.

[@syedtauha4001]

You're the FATHER OF SCIENCE

[@kennyqueen7861]

hi, thanks for this wonderful explanation. so after i got the fundamental knowledge from here, i went to read further on the cytoplasm membrane and its compose of the caveoli, can u pls explain its function. thanks

[@DapaChrons]

desmin and vimentin, in case anyone was wondering about the spelling

[@amnamehmood7659]

thanks a ton! From Pakistan ✌

[@gorgeousgirl7166]

can the single units of smooth muscles can be ether controlled by the NS or can b under the non nervous control ?

[@dikeledimonyepao743]

thank you so much...

[@Ing00]

awesome video!!

[@hendezzat3429]

Amazing! ❤️

[@EnsiklopediaAhmadFauzi]

waww,,,,, Thank U so much... U're cooll dude ... I am agree with @chi an luu

[@AKLECTURES]

Fauzi Ahmad thanks! :)

[@منهاجالحياة-ك8ث]

+AK LECTURES (Andrey K) thank you so much can you explain atrophy and hypertrophy of skeletal muscle please?

[@farahalomar125]

Thanks❤️❤️❤️❤️

[@kikibear12146]

AMAZINGGG VIDEOO!!!!!

[@sciencenerd7639]

very nice

[@muhammadrais6777]

thanks bro keep it up

[@itstanii_5649]

"And what that means is..."

[@Cass_i]

I think you mean : " And what that meeeaans is"

[@isaactrujillo8119]

good though, thanks for the info!

[@ifrahhussein5344]

Does the heart have smooth muscle ?

[@yuhgghuh4068]

Why is smooth muscle not striated?

[@girlgame1957]

U are my degree saver😭

[@sumayamozumder1654]

Is that a siren?

[@AKLECTURES]

Sumaya Mozumder Yes, I live by a hospital in the city :) very busy streets!

[@Victormusicworld]

i love you. Can i order an AK lectures tshirt to romania? :D thx

[@danielc.6156]

8:16 screenshot for notes :)

[@AKLECTURES]

you can also just download them from my website :)

[@jakeatherly5243]

Can you really do this for a living with 27k views and staff? I mean I love your lectures, they are incredible, but how can you survive in this economy on KZbin money?

[@AKLECTURES]

I can't and I don't. I have yet to get a penny from KZbin :)

[@jakeatherly5243]

+AK LECTURES (Andrey K) I have an enormous amount of respect for what you do. Thanks for the in depth lectures.

[@RenZara28]

Thank you for making our lives better huhu

[@khaledha2050]

💚💚🔥

[@isaactrujillo8119]

very fast

[@gorgeousgirl7166]

can the single units of smooth muscles can be ether controlled by the NS or can b under the non nervous control ?

[@DanielPena-nv2nj]

Yes - Smooth muscle can be controlled by a number of different stimuli, such as hormones (CCK, gastrin, histamine), pressure in blood vessels, stretching (very important!),changes in temperature, pH, O2 and CO2 levels.